Pharmacodynamics of piperacillin alone and in combination with tazobactam against piperacillin-resistant and -susceptible organisms in an in vitro model of infection

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Pharmacodynamics of piperacillin alone and in combination with tazobactam against piperacillin-resistant and -susceptible organisms in an in vitro model of infection is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AAC.38.10.2351
P932PMC publication ID284743
P698PubMed publication ID7840569
P5875ResearchGate publication ID15357794

P2093author name stringDudley MN
Zinner SH
Medeiros AA
Gilbert DH
Pivarnik P
Strayer AH
P2860cites workComparative in vitro activities of piperacillin-tazobactam and ticarcillin-clavulanateQ35343060
Comparative in vitro and in vivo activities of piperacillin combined with the beta-lactamase inhibitors tazobactam, clavulanic acid, and sulbactamQ35360429
Comparative activity of beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with beta-lactams against beta-lactamase-producing anaerobesQ35575783
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate, and sulbactam combined with ampicillin and broad-spectrum penicillins against defined beta-lactamase-producing aerobic gram-negative bacilliQ35650267
Continuous infusion of beta-lactam antibioticsQ35656806
Dose ranging and fractionation of intravenous ciprofloxacin against Pseudomonas aeruginosa and Staphylococcus aureus in an in vitro model of infectionQ35818681
Influence of beta-lactamase inhibitors on the potency of their companion drug with organisms possessing class I enzymesQ36754084
Piperacillin-tazobactam versus imipenem-cilastatin for treatment of intra-abdominal infectionsQ36758337
Dissemination of the novel plasmid-mediated beta-lactamase CTX-1, which confers resistance to broad-spectrum cephalosporins, and its inhibition by beta-lactamase inhibitorsQ39817435
Kinetic interactions of tazobactam with beta-lactamases from all major structural classesQ39865634
Meeting the challenges of beta-lactamasesQ40884630
Determinants of the activity of beta-lactamase inhibitor combinationsQ40884640
The in-vitro activity of piperacillin/tazobactam, ciprofloxacin, ceftazidime and imipenem against multiple resistant gram-negative bacteriaQ44039660
Antibacterial activity of piperacillin and tazobactam against beta-lactamase-producing clinical isolates.Q54335837
Transferable resistance to third-generation cephalosporins in clinical isolates of Klebsiella pneumoniae: identification of CTX-1, a novel beta-lactamase.Q54401131
In-vitro bacterial killing kinetics of ticarcillin/clavulanic acid.Q54411156
Single-dose pharmacokinetics of piperacillin and tazobactam in patients with renal diseaseQ67485735
In vitro effect of YTR (tazobactam) on plasmid and chromosomally mediated beta-lactamasesQ68459304
Determination of tazobactam and piperacillin in human plasma, serum, bile and urine by gradient elution reversed-phase high-performance liquid chromatographyQ69360876
Comparative activities of the beta-lactamase inhibitors YTR 830, clavulanate and sulbactam combined with extended-spectrum penicillins against ticarcillin-resistant Enterobacteriaceae and pseudomonadsQ70148102
Dose Dependence of Piperacillin PharmacokineticsQ72758425
Therapy of soft tissue infections with piperacillin/tazobactamQ72956634
Efficacy, safety and tolerance of parenteral piperacillin/tazobactam in the treatment of patients with lower respiratory tract infectionsQ72956661
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectpharmacodynamicsQ725307
P1104number of pages6
P304page(s)2351-2356
P577publication date1994-10-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titlePharmacodynamics of piperacillin alone and in combination with tazobactam against piperacillin-resistant and -susceptible organisms in an in vitro model of infection
P478volume38

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cites work (P2860)
Q34680546Clinical correlation of the CLSI susceptibility breakpoint for piperacillin- tazobactam against extended-spectrum-beta-lactamase-producing Escherichia coli and Klebsiella species
Q36730017Combinatorial Pharmacodynamics of Ceftolozane-Tazobactam against Genotypically Defined β-Lactamase-Producing Escherichia coli: Insights into the Pharmacokinetics/Pharmacodynamics of β-Lactam-β-Lactamase Inhibitor Combinations.
Q35128789Efficacy of ampicillin-sulbactam is not dependent upon maintenance of a critical ratio between components: sulbactam pharmacokinetics in pharmacodynamic interactions
Q39844968Expression of the AsbA1, OXA-12, and AsbM1 beta-lactamases in Aeromonas jandaei AER 14 is coordinated by a two-component regulon
Q33559047Identification of optimal renal dosage adjustments for traditional and extended-infusion piperacillin-tazobactam dosing regimens in hospitalized patients.
Q35134525Importance of beta-lactamase inhibitor pharmacokinetics in the pharmacodynamics of inhibitor-drug combinations: studies with piperacillin-tazobactam and piperacillin-sulbactam.
Q34320027In vivo activities of ceftolozane, a new cephalosporin, with and without tazobactam against Pseudomonas aeruginosa and Enterobacteriaceae, including strains with extended-spectrum β-lactamases, in the thighs of neutropenic mice.
Q37625193Pharmacodynamic profiling of piperacillin in the presence of tazobactam in patients through the use of population pharmacokinetic models and Monte Carlo simulation
Q40288977Pharmacodynamics of ceftazidime plus the serine beta-lactamase inhibitor AM-112 against Escherichia coli containing TEM-1 and CTX-M-1 beta-lactamases
Q40325943Pharmacodynamics of β-lactamase inhibition by NXL104 in combination with ceftaroline: examining organisms with multiple types of β-lactamases
Q38664871Pharmacokinetics and pharmacodynamics in antibiotic dose optimization.
Q34462071Pharmacokinetics of piperacillin/tazobactam in cancer patients with hematological malignancies and febrile neutropenia after chemotherapy
Q43085417Pharmacokinetics-pharmacodynamics of tazobactam in combination with ceftolozane in an in vitro infection model
Q39001350Pharmacokinetics/pharmacodynamics of a β-lactam and β-lactamase inhibitor combination: a novel approach for aztreonam/avibactam
Q42109987Pharmacological basis of β-lactamase inhibitor therapeutics: tazobactam in combination with Ceftolozane
Q36439015Population Pharmacokinetics and Pharmacodynamics of Extended-Infusion Piperacillin and Tazobactam in Critically Ill Children
Q33798377Population pharmacokinetic analysis of piperacillin in burn patients
Q41139120Population pharmacokinetics and pharmacodynamics of piperacillin and tazobactam administered by prolonged infusion in obese and nonobese patients
Q36158212Population pharmacokinetics of piperacillin in the early phase of septic shock: does standard dosing result in therapeutic plasma concentrations?
Q34216623Pulmonary penetration of piperacillin and tazobactam in critically ill patients.
Q39783646Relationships between antimicrobial effect and area under the concentration-time curve as a basis for comparison of modes of antibiotic administration: meropenem bolus injections versus continuous infusions
Q40389902The pharmacodynamics of avibactam in combination with ceftaroline or ceftazidime against β-lactamase-producing Enterobacteriaceae studied in an in vitro model of infection
Q26796425The β-Lactams Strike Back: Ceftazidime-Avibactam
Q39120027What we may expect from novel antibacterial agents in the pipeline with respect to resistance and pharmacodynamic principles

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