CD40 signaling in macrophages induces activity against an intracellular pathogen independently of gamma interferon and reactive nitrogen intermediates

scientific article

CD40 signaling in macrophages induces activity against an intracellular pathogen independently of gamma interferon and reactive nitrogen intermediates is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.73.5.3115-3123.2005
P932PMC publication ID1087328
P698PubMed publication ID15845519

P50authorCarlos S. SubausteQ45702144
P2093author name stringJose-Andres C Portillo
Matthew Wessendarp
Rosa M Andrade
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The CD40/CD40 ligand interaction is required for resistance to toxoplasmic encephalitis.Q34003535
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Preferential activation and expansion of human peripheral blood gamma delta T cells in response to Toxoplasma gondii in vitro and their cytokine production and cytotoxic activity against T. gondii-infected cellsQ35751460
Nitric oxide produced during murine listeriosis is protectiveQ35775501
Macrophage oxygen-dependent antimicrobial activity. II. The role of oxygen intermediatesQ36342907
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Reactivation of latent leishmaniasis by inhibition of inducible nitric oxide synthaseQ36366480
CD40 Signaling Is Impaired in L. major–infected Macrophages and Is Rescued by a p38MAPK Activator Establishing a Host-protective Memory T Cell ResponseQ36370688
Inducible nitric oxide is essential for host control of persistent but not acute infection with the intracellular pathogen Toxoplasma gondiiQ36377044
Intracellular antimicrobial activity in the absence of interferon-gamma: effect of interleukin-12 in experimental visceral leishmaniasis in interferon-gamma gene-disrupted miceQ36377093
Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharideQ38318972
Regulation of biosynthesis of nitric oxide.Q40389134
Structural characteristics of CD40 ligand that determine biological functionQ40397892
IL-4-activated STAT-6 inhibits IFN-gamma-induced CD40 gene expression in macrophages/microgliaQ40841314
CD40-CD40 ligand interaction is central to cell-mediated immunity against Toxoplasma gondii: patients with hyper IgM syndrome have a defective type 1 immune response that can be restored by soluble CD40 ligand trimerQ41669050
Novel human immunodeficiencies reveal the essential role of type-I cytokines in immunity to intracellular bacteriaQ43487749
Release of nitric oxide during the T cell-independent pathway of macrophage activation. Its role in resistance to Listeria monocytogenesQ44378254
Altered immune responses in mice lacking inducible nitric oxide synthaseQ44662136
Decreased resistance of TNF receptor p55- and p75-deficient mice to chronic toxoplasmosis despite normal activation of inducible nitric oxide synthase in vivoQ44728471
Pathogen-specific induction of CD154 is impaired in CD4+ T cells from human immunodeficiency virus-infected patientsQ45701450
Divergent role for TNF-alpha in IFN-gamma-induced killing of Toxoplasma gondii and Salmonella typhimurium contributes to selective susceptibility of patients with partial IFN-gamma receptor 1 deficiencyQ50107286
Factors involved in regulating primary and secondary immunity to infection with Histoplasma capsulatum: TNF-alpha plays a critical role in maintaining secondary immunity in the absence of IFN-gamma.Q52039631
Production of nitric oxide (NO) is not essential for protection against acute Toxoplasma gondii infection in IRF-1-/- mice.Q52518296
Disruption of CD40-CD40 ligand interactions results in an enhanced susceptibility to Leishmania amazonensis infection.Q52519428
IL-4 neutralization or TNF-alpha treatment ameliorate disease by an intracellular pathogen in IFN-gamma receptor-deficient mice.Q52522760
The role of CD40L in T cell-dependent nitric oxide production by murine macrophages.Q52541962
Murine CD8+ cytotoxic T lymphocytes lyse Toxoplasma gondii-infected cells.Q54283162
Inhibition of macrophage and endothelial cell nitric oxide synthase by diphenyleneiodonium and its analogs 1Q55042584
Activated macrophages destroy intracellular Leishmania major amastigotes by an L-arginine-dependent killing mechanismQ67267340
Cytokine gene expression after in vivo primary immunization with goat antibody to mouse IgD antibodyQ67701284
IFN-gamma-induced L-arginine-dependent toxoplasmastatic activity in murine peritoneal macrophages is mediated by endogenous tumor necrosis factor-alphaQ67724002
Microbiostatic effect of murine-activated macrophages for Toxoplasma gondii. Role for synthesis of inorganic nitrogen oxides from L-arginineQ68739930
Protective role of CD40 in Leishmania major infection at two distinct phases of cell-mediated immunityQ71066501
CD40 ligand is required for protective cell-mediated immunity to Leishmania majorQ71066505
Altered responses to bacterial infection and endotoxic shock in mice lacking inducible nitric oxide synthaseQ71694221
Deleterious effect of HIV-1 plasma viremia on B cell costimulatory functionQ73496374
T lymphocyte and monocyte interaction by CD40/CD40 ligand facilitates a lymphoproliferative response and killing of Cryptococcus neoformans in vitroQ73812495
CD40/CD40 ligand interactions in the host defense against disseminated Candida albicans infection: the role of macrophage-derived nitric oxideQ78022357
CD154 activates macrophage antimicrobial activity in the absence of IFN-gamma through a TNF-alpha-dependent mechanismQ79353958
P433issue5
P407language of work or nameEnglishQ1860
P304page(s)3115-3123
P577publication date2005-05-01
P1433published inInfection and ImmunityQ6029193
P1476titleCD40 signaling in macrophages induces activity against an intracellular pathogen independently of gamma interferon and reactive nitrogen intermediates
P478volume73

Reverse relations

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