A Ty1 integrase nuclear localization signal required for retrotransposition

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A Ty1 integrase nuclear localization signal required for retrotransposition is …
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scholarly articleQ13442814

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P356DOI10.1128/MCB.18.2.1105
P8608Fatcat IDrelease_on4ibkbvazcc7o6eb2lgd4pvxi
P932PMC publication ID108823
P698PubMed publication ID9448008

P2093author name stringMoore SP
Garfinkel DJ
Rinckel LA
P2860cites workActive nuclear import of human immunodeficiency virus type 1 preintegration complexesQ24564507
The Vpr protein of human immunodeficiency virus type 1 influences nuclear localization of viral nucleic acids in nondividing host cellsQ24564509
The nuclear localization signal of the matrix protein of human immunodeficiency virus type 1 allows the establishment of infection in macrophages and quiescent T lymphocytesQ24564711
HIV-1 infection of nondividing cells through the recognition of integrase by the importin/karyopherin pathwayQ24642513
Role of the basic domain of human immunodeficiency virus type 1 matrix in macrophage infectionQ24673913
Nuclear targeting sequences--a consensus?Q27860997
Invading the yeast nucleus: a nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivoQ27929507
Improved method for high efficiency transformation of intact yeast cellsQ28131608
Immunofluorescence methods for yeastQ28131617
A nuclear localization signal within HIV-1 matrix protein that governs infection of non-dividing cellsQ28249434
Nucleocytoplasmic transportQ28275907
HIV nuclear import is governed by the phosphotyrosine-mediated binding of matrix to the core domain of integraseQ28291170
Phosphorylation of residue 131 of HIV-1 matrix is not required for macrophage infectionQ28302074
Two interdependent basic domains in nucleoplasmin nuclear targeting sequence: identification of a class of bipartite nuclear targeting sequenceQ29547917
Specific enzymatic amplification of DNA in vitro: the polymerase chain reactionQ29618837
Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytesQ29619514
Integration of murine leukemia virus DNA depends on mitosisQ34051046
Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complexQ34057841
Comparative mutagenesis of nuclear localization signals reveals the importance of neutral and acidic amino acidsQ34396948
Expression and partial purification of enzymatically active recombinant Ty1 integrase in Saccharomyces cerevisiaeQ35077531
Subcellular localization of avian sarcoma virus and human immunodeficiency virus type 1 integrasesQ35876147
Zinc folds the N-terminal domain of HIV-1 integrase, promotes multimerization, and enhances catalytic activityQ35922636
Human immunodeficiency virus type 1 viral protein R localization in infected cells and virionsQ36654319
Efficient Homologous Recombination of Ty1 Element cDNA When Integration Is BlockedQ36666908
Functional organization of the retrotransposon Ty from Saccharomyces cerevisiae: Ty protease is required for transpositionQ36786045
Proteolytic processing of pol-TYB proteins from the yeast retrotransposon Ty1Q36797578
Residues critical for retroviral integrative recombination in a region that is highly conserved among retroviral/retrotransposon integrases and bacterial insertion sequence transposasesQ36815395
Single-step selection for Ty1 element retrotranspositionQ37389260
How proteins enter the nucleusQ37632736
Positional information within the Mu transposase tetramer: catalytic contributions of individual monomersQ38358053
The slow infection caused by visna virusQ39371180
Passage through mitosis is required for oncoretroviruses but not for the human immunodeficiency virusQ40037960
The regulation of protein transport to the nucleus by phosphorylationQ40375235
Nuclear localization signals (NLS).Q40780737
Complementation between HIV integrase proteins mutated in different domainsQ40873688
Human immunodeficiency virus infection of cells arrested in the cell cycleQ41531689
Ty1 in vitro integration: effects of mutations in cis and in transQ41885565
Productive human immunodeficiency virus type 1 (HIV-1) infection of nonproliferating human monocytesQ41994305
In-frame linker insertion mutagenesis of yeast transposon Ty1: mutations, transposition and dominanceQ42602230
Intracellular transport of the murine leukemia virus during acute infection of NIH 3T3 cells: nuclear import of nucleocapsid protein and integrase.Q42824697
Strand exchange protein 1 from Saccharomyces cerevisiae. A novel multifunctional protein that contains DNA strand exchange and exonuclease activitiesQ43422132
Reverse transcriptase activity and Ty RNA are associated with virus-like particles in yeastQ43603969
Retroviral integrase functions as a multimer and can turn over catalyticallyQ44439274
Multimerization determinants reside in both the catalytic core and C terminus of avian sarcoma virus integraseQ45790359
The DNA intermediate in yeast Ty1 element transposition copurifies with virus-like particles: cell-free Ty1 transpositionQ45841053
Ty element transposition: reverse transcriptase and virus-like particlesQ45848654
A specific terminal structure is required for Ty1 transpositionQ68459474
Ty elements transpose through an RNA intermediateQ70078812
Negative charge at the casein kinase II site flanking the nuclear localization signal of the SV40 large T-antigen is mechanistically important for enhanced nuclear importQ72185085
The SPT3 gene is required for normal transcription of Ty elements in S. cerevisiaeQ72405342
P433issue2
P407language of work or nameEnglishQ1860
P304page(s)1105-1114
P577publication date1998-02-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleA Ty1 integrase nuclear localization signal required for retrotransposition
P478volume18

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cites work (P2860)
Q33957578A new member of the Sin3 family of corepressors is essential for cell viability and required for retroelement propagation in fission yeast
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Q35054036Coordinate nuclear targeting of the FANCD2 and FANCI proteins via a FANCD2 nuclear localization signal
Q38294642Dimerization of the DYT6 dystonia protein, THAP1, requires residues within the coiled-coil domain
Q40846853Directing proteins to nucleus by fusion to nuclear localization signal tags
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Q41783121Expression of an active form of recombinant Ty1 reverse transcriptase in Escherichia coli: a fusion protein containing the C-terminal region of the Ty1 integrase linked to the reverse transcriptase-RNase H domain exhibits polymerase and RNase H acti
Q39603659Frameshift signal transplantation and the unambiguous analysis of mutations in the yeast retrotransposon Ty1 Gag-Pol overlap region
Q37333915Functional analysis of N-terminal residues of ty1 integrase
Q31150177Functional genomics reveals relationships between the retrovirus-like Ty1 element and its host Saccharomyces cerevisiae.
Q27932614Fus3 controls Ty1 transpositional dormancy through the invasive growth MAPK pathway
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Q41899907Host factors that affect Ty3 retrotransposition in Saccharomyces cerevisiae
Q31117182Increase in Ty1 cDNA recombination in yeast sir4 mutant strains at high temperature
Q43733396Inhibition of reverse transcription in vivo by elevated manganese ion concentration
Q39528946Integrase mediates nuclear localization of Ty3.
Q34485584Intracellular trafficking of retroviral genomes during the early phase of infection: viral exploitation of cellular pathways
Q27929507Invading the yeast nucleus: a nuclear localization signal at the C terminus of Ty1 integrase is required for transposition in vivo
Q24562936LEDGF/p75 determines cellular trafficking of diverse lentiviral but not murine oncoretroviral integrase proteins and is a component of functional lentiviral preintegration complexes
Q31965068Libraries of green fluorescent protein fusions generated by transposition in vitro
Q39548812Mutations in nonconserved domains of Ty3 integrase affect multiple stages of the Ty3 life cycle
Q33546898New lines of host defense: inhibition of Ty1 retrotransposition by Fus3p and NER/TFIIH.
Q33671175Nuclear import of human immunodeficiency virus type-1 preintegration complexes.
Q37513942Nuclear localization signals and human disease
Q27933256Nucleotide excision repair/TFIIH helicases RAD3 and SSL2 inhibit short-sequence recombination and Ty1 retrotransposition by similar mechanisms
Q33959010Nup124p is a nuclear pore factor of Schizosaccharomyces pombe that is important for nuclear import and activity of retrotransposon Tf1.
Q64388709Patching broken chromosomes with extranuclear cellular DNA
Q73931519Possible regulatory function of the Saccharomyces cerevisiae Ty1 retrotransposon core protein
Q35185882Retrotransposon suicide: formation of Ty1 circles and autointegration via a central DNA flap
Q27938075Retrotransposons. An RNA polymerase III subunit determines sites of retrotransposon integration.
Q36225316Reverse transcriptase and integrase of the Saccharomyces cerevisiae Ty1 element
Q46235556Ribosome Biogenesis Modulates Ty1 Copy Number Control in Saccharomyces cerevisiae.
Q41827820Role of integrase in reverse transcription of the Saccharomyces cerevisiae retrotransposon Ty1.
Q27676772Structural basis of high-affinity nuclear localization signal interactions with importin-α
Q39528168Targeting of the yeast Ty5 retrotransposon to silent chromatin is mediated by interactions between integrase and Sir4p
Q52376071The Mediator co-activator complex regulates Ty1 retromobility by controlling the balance between Ty1i and Ty1 promoters.
Q33969162The Sgs1 helicase of Saccharomyces cerevisiae inhibits retrotransposition of Ty1 multimeric arrays
Q36898954The T body, a new cytoplasmic RNA granule in Saccharomyces cerevisiae
Q35441519The Ty1 LTR-retrotransposon of budding yeast, Saccharomyces cerevisiae
Q41173696The Ty1 integrase protein can exploit the classical nuclear protein import machinery for entry into the nucleus
Q24816846The cell cycle independence of HIV infections is not determined by known karyophilic viral elements
Q33947325The yeast Ty virus-like particles
Q54260521The yeast Ty1 retrotransposon requires components of the nuclear pore complex for transcription and genomic integration.
Q33725396Transposable elements in Drosophila
Q39679321Ty1 Integrase Interacts with RNA Polymerase III-specific Subcomplexes to Promote Insertion of Ty1 Elements Upstream of Polymerase (Pol) III-transcribed Genes
Q34572716Ty1 copy number dynamics in Saccharomyces
Q36542538Ty1 gag enhances the stability and nuclear export of Ty1 mRNA.
Q34127303Ty1 integrase overexpression leads to integration of non-Ty1 DNA fragments into the genome of Saccharomyces cerevisiae
Q39601419Ty1 proteolytic cleavage sites are required for transposition: all sites are not created equal
Q37410670Ty3 nuclear entry is initiated by viruslike particle docking on GLFG nucleoporins
Q66679726Viral Appropriation: Laying Claim to Host Nuclear Transport Machinery
Q45428036Virus-like particle formation in Drosophila melanogaster germ cells suggests a complex translational regulation of the retrotransposon cycle and new mechanisms inhibiting transposition
Q33890305Viruses, microorganisms and scientists meet the nuclear pore. Leysin, VD, Switzerland, February 26-March 1, 1998.
Q74764328Yeast retrotransposons: finding a nice quiet neighborhood

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