Herpesvirus saimiri

scientific article

Herpesvirus saimiri is …
instance of (P31):
scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1098/RSTB.2000.0780
P932PMC publication ID1088444
P698PubMed publication ID11313011
P5875ResearchGate publication ID12021809

P2093author name stringFleckenstein B
Fickenscher H
P2860cites workIsolation of HIV type 1 from long-term nonprogressors in Herpesvirus saimiri-immortalized T cellsQ78170071
The collagen repeat sequence is a determinant of the degree of herpesvirus saimiri STP transforming activityQ95789811
Induction of a novel cellular homolog of interleukin-10, AK155, by transformation of T lymphocytes with herpesvirus saimiriQ22253378
Human IL-17: a novel cytokine derived from T cellsQ24304404
CTLA-8, cloned from an activated T cell, bearing AU-rich messenger RNA instability sequences, and homologous to a herpesvirus saimiri geneQ24315956
Tap: a novel cellular protein that interacts with tip of herpesvirus saimiri and induces lymphocyte aggregationQ24336654
Selective expression of a protein-tyrosine kinase, p56lyn, in hematopoietic cells and association with production of human T-cell lymphotropic virus type IQ24608015
T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokinesQ24678115
Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcomaQ28242984
TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleusQ28276214
Suppression of the human immunodeficiency virus long terminal repeat by CD8+ T cells is dependent on the NFAT-1 elementQ28291717
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptorQ28609151
Herpesvirus ateles gene product Tio interacts with nonreceptor protein tyrosine kinasesQ30175764
The Lck binding domain of herpesvirus saimiri tip-484 constitutively activates Lck and STAT3 in T cellsQ30175910
Mutation of the Lck-binding motif of Tip enhances lymphoid cell activation by herpesvirus saimiri.Q30176261
Downregulation of Lck-mediated signal transduction by tip of herpesvirus saimiriQ30192907
Distinct functional domains of STP-C488 of herpesvirus saimiriQ30419972
Herpesvirus ateles DNA and Its Homology with Herpesvirus saimiri Nucleic AcidQ33542373
Herpesvirus saimiri strategies for T cell stimulation and transformation.Q33595561
Tumour induction with DNA of oncogenic primate herpesvirusesQ33676473
Substitution of ras for the herpesvirus saimiri STP oncogene in lymphocyte transformationQ33782629
Antiapoptotic herpesvirus Bcl-2 homologs escape caspase-mediated conversion to proapoptotic proteinsQ33787044
Transformation to continuous growth of primary human T lymphocytes by human T-cell leukemia virus type I X-region genes transduced by a Herpesvirus saimiri vectorQ33854474
Type C virus particles in a cord T-cell line derived by co-cultivating normal human cord leukocytes and human leukaemic T cellsQ34253011
Expression of IL-2 and IL-4 in T lymphocytes transformed by herpesvirus saimiriQ34310375
The family Herpesviridae: an update. The Herpesvirus Study Group of the International Committee on Taxonomy of VirusesQ34380188
Mouse IL-17: a cytokine preferentially expressed by alpha beta TCR + CD4-CD8-T cellsQ34403468
Impairment of mycobacterial immunity in human interleukin-12 receptor deficiencyQ34469625
An integral membrane protein (LMP2) blocks reactivation of Epstein-Barr virus from latency following surface immunoglobulin crosslinkingQ35000168
STP and Tip are essential for herpesvirus saimiri oncogenicityQ39642318
Herpesvirus saimiri-transformed human CD4+ T-cell lines: an efficient target cell system for the analysis of human immunodeficiency virus-specific cytotoxic CD8+ T-lymphocyte activity.Q39642465
The complement control protein homolog of herpesvirus saimiri regulates serum complement by inhibiting C3 convertase activityQ39870476
Immortalization of human T cells expressing T-cell receptor gamma delta by herpesvirus saimiriQ39872839
The A+T-rich genome of Herpesvirus saimiri contains a highly conserved gene for thymidylate synthase.Q35607156
Inhibition of intracellular transport of B cell antigen receptor complexes by Kaposi's sarcoma-associated herpesvirus K1Q35834640
A herpesvirus saimiri protein required for interleukin-2 independence is associated with membranes of transformed T cellsQ35842059
A herpesvirus saimiri membrane protein required for interleukin-2 independence forms a stable complex with p56lckQ35853952
Identification of a herpesvirus Saimiri cis-acting DNA fragment that permits stable replication of episomes in transformed T cellsQ35856906
Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytesQ35868015
Functional phenotype of transformed human alphabeta and gammadelta T cells determined by different subgroup C strains of herpesvirus SaimiriQ35879209
The herpesvirus saimiri ORF50 gene, encoding a transcriptional activator homologous to the Epstein-Barr virus R protein, is transcribed from two distinct promoters of different temporal phasesQ35880026
Genetic variation of herpesvirus saimiri subgroup A transforming protein and its association with cellular srcQ35883455
Herpesvirus saimiri encodes a functional homolog of the human bcl-2 oncogeneQ35884417
Activation of STAT transcription factors by herpesvirus Saimiri Tip-484 requires p56lckQ35891536
Conservation of gene organization in the lymphotropic herpesviruses herpesvirus Saimiri and Epstein-Barr virusQ36305748
Herpesvirus saimiri strain 11 immortalizes a restricted marmoset T8 lymphocyte subpopulation in vitroQ36352890
Herpesvirus ateles and herpesvirus saimiri transform marmoset T cells into continuously proliferating cell lines that can mediate natural killer cell-like cytotoxicityQ36375578
An apparently new herpesvirus from primary kidney cultures of the squirrel monkey (Saimiri sciureus).Q36508210
Herpesvirus saimiri. II. Experimentally induced malignant lymphoma in primatesQ36508614
Herpesvirus ateles, a new lymphoma virus of monkeysQ36522729
The superantigen-homologous viral immediate-early gene ie14/vsag in herpesvirus saimiri-transformed human T cells.Q36548648
Structure of nonintegrated, circular Herpesvirus saimiri and Herpesvirus ateles genomes in tumor cell lines and in vitro-transformed cellsQ36596809
Transformation of human T-cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cellsQ36687176
Regulation of the herpesvirus saimiri (HVS) delayed-early 110-kilodalton promoter by HVS immediate-early gene products and a homolog of the Epstein-Barr virus R trans activatorQ36688920
Herpesvirus saimiri oncogene STP-C488 encodes a phosphoproteinQ36693738
Role of human T-cell leukemia virus type 1 X region proteins in immortalization of primary human lymphocytes in cultureQ36699176
Primary structure of the herpesvirus saimiri genomeQ36701076
Karyotypic characterization of human T-cell lines immortalized by Herpesvirus saimiriQ36763313
Complete nucleotide sequence of the mouse CTLA8 geneQ36801895
Identification and characterization of the herpesvirus saimiri oncoprotein STP-C488Q36828959
Deletion mutants of herpesvirus saimiri define an open reading frame necessary for transformationQ36829775
Herpesvirus saimiri strains from three DNA subgroups have different oncogenic potentials in New Zealand white rabbitsQ36830147
Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptorsQ36852093
Nononcogenic deletion mutants of herpesvirus saimiri are defective for in vitro immortalization.Q36858457
Conservation of sequence and function between the product of the 52-kilodalton immediate-early gene of herpesvirus saimiri and the BMLF1-encoded transcriptional effector (EB2) of Epstein-Barr virusQ36872354
Organization of the thymidylate synthase gene of herpesvirus saimiriQ36883640
Immediate-early transcription of Herpesvirus saimiriQ36893726
Herpes-Type Virus and Chromosome Marker in Normal Leukocytes after Growth with Irradiated Burkitt CellsQ43805008
Human T cell leukemia/lymphoma virus type I infection of a CD4+ proliferative/cytotoxic T cell clone progresses in at least two distinct phases based on changes in function and phenotype of the infected cellsQ43869119
Transplantation and Cytogenetic Studies of Herpesvirus saimiri-Induced Disease in Marmoset Monkeys2Q44290650
A region of the Herpesvirus saimiri genome required for oncogenicityQ45056211
The immunoreceptor tyrosine-based activation motif of Epstein-Barr virus LMP2A is essential for blocking BCR-mediated signal transductionQ45760793
Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmissionQ45774865
Transformation of human leukocytes by cocultivation with an adult T cell leukemia virus producer cell lineQ45793427
Functional alterations of herpes simplex virus-specific CD4+ multifunctional T cell clones following infection with human T lymphotropic virus type I.Q45847194
Herpesvirus saimiri-based gene delivery vectors maintain heterologous expression throughout mouse embryonic stem cell differentiation in vitro.Q45866572
Functional long-term thymidine kinase suicide gene expression in human T cells using a herpesvirus saimiri vectorQ45867362
Interleukin-17.Q47912598
A gene for dihydrofolate reductase in a herpesvirusQ48327700
Herpesvirus saimiri immortalization of alpha beta and gamma delta human T-lineage cells derived from CD34+ intrathymic precursors in vitro.Q51109689
Herpesvirus saimiri-transformed macaque T cells are tolerated and do not cause lymphoma after autologous reinfusion.Q53409919
Engagement of the CD4 receptor inhibits the interleukin-2-dependent proliferation of human T cells transformed by Herpesvirus saimiri.Q53473062
Epithelial tumours induced by a herpesvirus oncogene in transgenic mice.Q53474920
Immortalization with herpesvirus saimiri modulates the cytokine secretion profile of established Th1 and Th2 human T cell clones.Q53477168
Herpesvirus-transformed cytotoxic T-cell linesQ53571300
The gene product encoded by ORF 57 of herpesvirus saimiri regulates the redistribution of the splicing factor SC-35.Q53930982
The glycosylphosphatidylinositol-anchored CD59 protein stimulates both T cell receptor ζ/ZAP-70-dependent and -independent signaling pathways in T cellsQ58659242
An alternative pathway of T-cell activation: A functional role for the 50 kd T11 sheep erythrocyte receptor proteinQ58960509
Superantigen functionQ59019526
Conformational and Biochemical Differences in the TCR·CD3 Complex of CD8+VersusCD4+Mature Lymphocytes Revealed in the Absence of CD3γQ62024094
Atypical X-Linked Severe Combined Immunodeficiency Due to Possible Spontaneous Reversion of the Genetic Defect in T CellsQ63859659
Immortalization of human T cell clones by Herpesvirus saimiri. Signal transduction analysis reveals functional CD3, CD4, and IL-2 receptorsQ63859667
Herpesvirus ateles: properties of an oncogenic herpesvirus isolated from circulating lymphocytes of spider monkeys (Ateles sp.).Q68365871
Structural organization of the conserved gene block of Herpesvirus saimiri coding for DNA polymerase, glycoprotein B, and major DNA binding proteinQ68449645
Isolation of Herpesvirus saimiri from blood of squirrel monkeys (Saimiri sciureus)Q68642408
Pathologic Features of Herpesvirus ateles Lymphoma in Cotton-Topped Marmosets (Saguinus oedipus)2Q69380521
Herpesvirus ateles immortalizes in vitro a CD3+CD4+CD8+ marmoset lymphocyte with NK functionQ69816802
Activation of a myelin basic protein-specific human T cell clone by antigen-presenting cells from rhesus monkeysQ71577760
Defective actin reorganization and polymerization of Wiskott-Aldrich T cells in response to CD3-mediated stimulationQ73894658
Phenotypical and functional characterization of Herpesvirus saimiri-immortalized human major histocompatibility complex class II-deficient T lymphocytesQ74460081
Anti-apoptotic strategies of lymphotropic virusesQ77454770
Herpesvirus saimiri Tip-484 membrane protein markedly increases p56lck activity in T cellsQ39877694
A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation.Q39880612
Primary structure of the alcelaphine herpesvirus 1 genome.Q39880813
Enhanced downregulation of Lck-mediated signal transduction by a Y114 mutation of herpesvirus Saimiri tip.Q39881073
Association of the viral oncoprotein STP-C488 with cellular ras.Q40017684
Mononuclear Cell Fraction Carrying Herpesvirus saimiri in Persistently Infected Squirrel Monkeys 2 3Q40034336
Inhibition of complement-mediated cytolysis by the terminal complement inhibitor of herpesvirus saimiri.Q40038846
Phenotypic and functional consequences of herpesvirus saimiri infection of human CD8+ cytotoxic T lymphocytes.Q40047708
The presence ofherpesvirus saimiri genomes in virus-transformed cellsQ40058479
New member of the multigene family of complement control proteins in herpesvirus saimiriQ40066082
Selectable recombinant herpesvirus saimiri is capable of persisting in a human T-cell lineQ40104126
trans activation of the thymidylate synthase promoter of herpesvirus saimiri.Q40104786
Immortalization of human T cells by Herpesvirus saimiriQ40611273
The molecular biology of leukocyte chemoattractant receptorsQ40661169
Superantigens and retroviral infection: insights from mouse mammary tumor virusQ40759821
A novel CD18 genomic deletion in a patient with severe leucocyte adhesion deficiency: a possible CD2/lymphocyte function-associated antigen-1 functional association in humans.Q40774385
Distinct transcriptional and functional properties of the R transactivator gene orf50 of the transforming herpesvirus saimiri strain C488.Q40898975
T cell-derived suppressive activity: evidence of autocrine noncytolytic control of HIV type 1 transcription and replicationQ40914860
Herpes virus saimiri transformation of T cells in CD3 gamma immunodeficiency: phenotypic and functional characterization.Q40920243
Induction of apoptosis in Herpesvirus saimiri-immortalized T lymphocytes by blocking interaction of CD28 with CD80/CD86.Q40928129
CD2-mediated CD59 stimulation in keratinocytes results in secretion of IL-1alpha, IL-6, and GM-CSF: implications for the interaction of keratinocytes with intraepidermal T lymphocytesQ40952222
Assessment of Herpesvirus saimiri as a potential human gene therapy vectorQ40972532
Herpesvirus saimiri transformation of HIV type 1 suppressive CD8+ lymphocytes from an HIV type 1-infected asymptomatic individualQ41047644
Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirusQ41050488
A human T-cell leukemia virus Tax variant incapable of activating NF-kappaB retains its immortalizing potential for primary T-lymphocytesQ41050877
Constitutive activation of TCR signaling molecules in IL-2-independent Herpesvirus saimiri-transformed T cells.Q41060150
Activation induces apoptosis in Herpesvirus saimiri-transformed T cells independent of CD95 (Fas, APO-1).Q41077466
Herpes viral cyclin/Cdk6 complexes evade inhibition by CDK inhibitor proteins.Q41079253
Isolation and characterization of transformed human T-cell lines infected by Epstein-Barr virusQ41104640
Herpesvirus saimiri-immortalized human T-cells support long-term, high titred replication of human immunodeficiency virus types 1 and 2.Q41107776
Herpesvirus saimiri CD59--baculovirus expression and characterisation of complement inhibitory activityQ41112067
Growth transformation of antigen-specific T cell lines from rhesus monkeys by herpesvirus saimiriQ41121405
Generation of herpes virus saimiri-transformed T-cell lines from macaques is restricted by reactivation of simian spuma virusesQ41121421
Derivation of herpesvirus saimiri-transformed CD8+ T cell lines with noncytotoxic anti-HIV activityQ41124356
The latent membrane protein 2 gene of Epstein-Barr virus is important for efficient B cell immortalizationQ41154270
Herpesvirus saimiri-transformed human CD4+ T cells can provide polyclonal B cell help via the CD40 ligand as well as the TNF-alpha pathway and through release of lymphokinesQ41156391
Synthesis of the CC-chemokines MIP-1alpha, MIP-1beta, and RANTES is associated with a type 1 immune response.Q41158653
In vitro immortalization of Old World monkey T lymphocytes with Herpesvirus saimiri: its susceptibility to infection with simian immunodeficiency virusesQ41205848
Herpesvirus saimiri immortalized gamma delta T cell line activated by IL-12.Q41205935
Selective activation of T cell kinase p56lck by Herpesvirus saimiri protein tip.Q41239646
Suppression of activation of the human immunodeficiency virus long terminal repeat by CD8+ T cells is not lentivirus specificQ41276077
The product of the Herpesvirus saimiri open reading frame 1 (tip) interacts with T cell-specific kinase p56lck in transformed cellsQ41361412
A cytotoxic CD40/p55 tumor necrosis factor receptor hybrid detects CD40 ligand on herpesvirus saimiri-transformed T cellsQ41404352
Polyclonal B cell activation induced by herpesvirus saimiri-transformed human CD4+ T cell clones. Role for membrane TNF-alpha/TNF-alpha receptors and CD2/CD58 interactions.Q41427108
Virus-encoded cyclinQ41431627
Cytokine dependence of human to mouse graft-versus-host diseaseQ41459235
Herpes virus saimiri-transformed human T lymphocytes: normal functional phenotype and preserved T cell receptor signallingQ41539412
Herpesvirus saimiri transformed human T cell lines: a permissive system for human immunodeficiency virusesQ41549916
Resistance of human fibroblasts to c-fos mediated transformationQ41549978
Interleukin-17 and its receptorQ41609403
Persistence of Selectable Herpesvirus Saimiri in Various Human Haematopoietic and Epithelial Cell LinesQ41673086
A pair of selectable herpesvirus vectors for simultaneous gene expression in human lymphoid cellsQ41678565
CD59 functions as a signal-transducing molecule for human T cell activationQ41679464
The divergence between two oncogenic Herpesvirus saimiri strains in a genomic region related to the transforming phenotypeQ41732638
CD2-mediated autocrine growth of herpes virus saimiri-transformed human T lymphocytesQ42192977
Differential expression of two immediate early genes of herpesvirus saimiri as detected by in situ hybridizationQ42543278
Asynchronous expression of the immediate-early protein of herpesvirus saimiri in populations of productively infected cells.Q42543432
A single major immediate-early virus gene product is synthesized in cells productively infected with herpesvirus saimiri.Q42543448
Analysis of nucleotide sequence of the rightmost 43 kbp of herpesvirus saimiri (HVS) L-DNA: General conservation of genetic organization between HVS and Epstein-Barr virusQ42599044
Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59Q42603024
Gene expression in cells infected with gammaherpesvirus saimiri: properties of transcripts from two immediate-early genesQ42615612
IL-2 independent growth and cytotoxicity of herpesvirus saimiri-infected human CD8 cells and involvement of two open reading frame sequences of the virusQ42617218
Herpesvirus saimiri open reading frame 14, a protein encoded by T lymphotropic herpesvirus, binds to MHC class II molecules and stimulates T cell proliferation.Q42628997
A Herpes saimiri oncogene causing peripheral T-cell lymphoma in transgenic mice.Q42629340
Identification of a cis-acting element within the herpesvirus saimiri ORF 6 promoter that is responsive to the HVS.R transactivatorQ42658578
Herpesvirus saimiri encodes homologues of G protein-coupled receptors and cyclinsQ43566357
Synthesis of bovine growth hormone in primates by using a herpesvirus vectorQ36895157
Classification of herpesvirus saimiri into three groups based on extreme variation in a DNA region required for oncogenicityQ36896856
Herpesvirus saimiri-induced lymphoblastoid rabbit cell line: growth characteristics, virus persistence, and oncogenic propertiesQ36904336
Construction of replication-competent Herpesvirus saimiri deletion mutants.Q36911716
Herpesvirus saimiri DNA in a lymphoid cell line established by in vitro transformationQ36913448
Deletion of DNA sequence in a nononcogenic variant of Herpesvirus saimiriQ36917047
In vitro immortalization of marmoset cells with three subgroups of herpesvirus saimiri.Q36919601
Herpesvirus saimiri strain variabilityQ36922745
Stable growth transformation of human T lymphocytes by herpesvirus saimiriQ36939191
Use of virion DNA as a cloning vector for the construction of mutant and recombinant herpesvirusesQ37251335
Methylation of Herpesvirus saimiri DNA in lymphoid tumor cell linesQ37339666
Transformation of human umbilical cord blood T cells by human T-cell leukemia/lymphoma virusQ37348020
Identification of transforming genes of subgroup A and C strains of Herpesvirus saimiriQ37575749
Specific oncolytic activity of herpesvirus saimiri in pancreatic cancer cells.Q38275092
Role of cellular tumor necrosis factor receptor-associated factors in NF-kappaB activation and lymphocyte transformation by herpesvirus Saimiri STP.Q39550436
Enhanced replication of M-tropic HIV-1 strains in Herpesvirus saimiri immortalised T-cells which express CCR5.Q39556363
Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirusQ39575857
Stimulation of cyclin-dependent kinase activity and G1- to S-phase transition in human lymphocytes by the human T-cell leukemia/lymphotropic virus type 1 Tax protein.Q39577374
The immediate-early gene product encoded by open reading frame 57 of herpesvirus saimiri modulates gene expression at a posttranscriptional levelQ39577543
Endogenous production of beta-chemokines by CD4+, but not CD8+, T-cell clones correlates with the clinical state of human immunodeficiency virus type 1 (HIV-1)-infected individuals and may be responsible for blocking infection with non-syncytium-indQ39577563
The open reading frame (ORF) 50a gene product regulates ORF 57 gene expression in herpesvirus saimiriQ39577750
Herpesvirus saimiri transforms human T-cell clones to stable growth without inducing resistance to apoptosis.Q39579218
T-cell lymphoma caused by herpesvirus saimiri C488 independently of ie14/vsag, a viral gene with superantigen homology.Q39579661
A role for herpesvirus saimiri orf14 in transformation and persistent infectionQ39579812
The interleukin-17 gene of herpesvirus saimiri.Q39582413
Antiapoptotic activity of the herpesvirus saimiri-encoded Bcl-2 homolog: stabilization of mitochondria and inhibition of caspase-3-like activity.Q39582480
Primary structure of the Herpesvirus ateles genomeQ39589112
Activation of lymphocyte signaling by the R1 protein of rhesus monkey rhadinovirusQ39589857
Herpesvirus saimiri vFLIP provides an antiapoptotic function but is not essential for viral replication, transformation, or pathogenicityQ39593823
Identification of the R1 oncogene and its protein product from the rhadinovirus of rhesus monkeysQ39594264
The activation domain of herpesvirus saimiri R protein interacts with the TATA-binding protein.Q39596816
Transformation of marmoset lymphocytesin vitro withherpesvirus atelesQ39600476
P433issue1408
P407language of work or nameEnglishQ1860
P1104number of pages23
P304page(s)545-567
P577publication date2001-04-01
P1433published inPhilosophical Transactions of the Royal Society BQ2153239
P1476titleHerpesvirus saimiri
P478volume356