XAV939: from a small inhibitor to a potent drug bioconjugate when delivered by gold nanoparticles

scientific article

XAV939: from a small inhibitor to a potent drug bioconjugate when delivered by gold nanoparticles is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1021/BC400271X
P8608Fatcat IDrelease_uvea6sahyzf6pd4qelszfyjoou
P932PMC publication ID4062623
P698PubMed publication ID24409808

P50authorLauren AustinQ80653461
P2093author name stringMostafa A El-Sayed
Megan A Mackey
Marwa M Afifi
P2860cites workTankyrase inhibition stabilizes axin and antagonizes Wnt signallingQ24316697
Wnt/beta-catenin signaling: components, mechanisms, and diseasesQ24630938
Wnt/beta-catenin signaling in development and diseaseQ27860784
Wnt and frizzled receptors as potential targets for immunotherapy in head and neck squamous cell carcinomasQ28202829
Wnt/β-catenin signalling in prostate cancerQ28269116
Determining the size and shape dependence of gold nanoparticle uptake into mammalian cellsQ29615461
Small molecule-mediated disruption of Wnt-dependent signaling in tissue regeneration and cancerQ29616163
A new nanotechnology technique for determining drug efficacy using targeted plasmonically enhanced single cell imaging spectroscopy.Q31112425
Cancer cell imaging and photothermal therapy in the near-infrared region by using gold nanorodsQ33233331
Noble Metals on the Nanoscale: Optical and Photothermal Properties and Some Applications in Imaging, Sensing, Biology, and MedicineQ62388562
Formation and Structure of Self-Assembled MonolayersQ77646341
The drug encapsulation efficiency, in vitro drug release, cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)-tocopheryl polyethylene glycol succinate nanoparticlesQ33237619
Tamoxifen-poly(ethylene glycol)-thiol gold nanoparticle conjugates: enhanced potency and selective delivery for breast cancer treatmentQ33516083
Nuclear targeting of gold nanoparticles in cancer cells induces DNA damage, causing cytokinesis arrest and apoptosisQ33525128
Nuclear targeted silver nanospheres perturb the cancer cell cycle differently than those of nanogoldQ34051464
The golden age: gold nanoparticles for biomedicineQ34081123
The gold standard: gold nanoparticle libraries to understand the nano-bio interfaceQ34316822
Expression of canonical WNT/β-CATENIN signaling components in the developing human lung.Q34356715
G1 cell-cycle control and cancerQ34368858
The effects of size, shape, and surface functional group of gold nanostructures on their adsorption and internalization by cellsQ34445676
Nanotechnology applications in cancerQ34619838
Defects in G1-S cell cycle control in head and neck cancer: a reviewQ34733424
Size-dependent in vivo toxicity of PEG-coated gold nanoparticlesQ35234739
Size-dependent antimicrobial properties of sugar-encapsulated gold nanoparticles synthesized by a green methodQ36499202
Gold nanoparticles in delivery applicationsQ37191739
Defining the role of integrin alphavbeta6 in cancerQ37550644
Nanomedicinal strategies to treat multidrug-resistant tumors: current progressQ37763152
New avenues to target Wnt/β-catenin signalingQ37812683
Nanomedicine.Q37821004
Role of canonical Wnt signaling in endometrial carcinogenesisQ37965633
The role of canonical WNT signaling pathway in oral carcinogenesis: a comprehensive review.Q37991676
The upcoming field of theranostic nanomedicine: an overviewQ38048806
Functionalized Gold Nanoparticles and Their Biomedical Applications.Q39203522
Nuclear targeting dynamics of gold nanoclusters for enhanced therapy of HER2+ breast cancerQ39448031
Size-dependent transfection efficiency of PEI-coated gold nanoparticlesQ39517970
Layer-by-layer coated gold nanoparticles: size-dependent delivery of DNA into cells.Q39565694
Gold nanoparticle sensitize radiotherapy of prostate cancer cells by regulation of the cell cycleQ39808184
Size-dependent cytotoxicity of gold nanoparticlesQ40061688
Peptide-conjugated gold nanorods for nuclear targetingQ40107238
The role of tamoxifen in combination with cisplatin on oral squamous cell carcinoma cell linesQ40309437
Induction of tumor-specific cytotoxicity and apoptosis by doxorubicinQ40427469
Synthesis and biological evaluation of dimeric RGD peptide-paclitaxel conjugate as a model for integrin-targeted drug delivery.Q40457486
Role of the alpha(v)beta6 integrin in human oral squamous cell carcinoma growth in vivo and in vitroQ43776784
Chitosan reduced gold nanoparticles as novel carriers for transmucosal delivery of insulinQ43834081
A quantum dot conjugated sugar ball and its cellular uptake. On the size effects of endocytosis in the subviral regionQ44909072
Rational and combinatorial design of peptide capping ligands for gold nanoparticlesQ45013356
Nanoparticle-mediated cellular response is size-dependent.Q47223945
Colloidal gold: a novel nanoparticle vector for tumor directed drug deliveryQ47325811
Design and potential application of PEGylated gold nanoparticles with size-dependent permeation through brain microvasculatureQ47374684
Activation of WNT family expression and signaling in squamous cell carcinomas of the oral cavityQ47880691
Aberrant activation of Wnt/β-catenin signaling pathway contributes to the sequential progression of DMBA-induced HBP carcinomas.Q51765264
P433issue2
P921main subjectnanoparticleQ61231
P304page(s)207-215
P577publication date2014-01-10
P1433published inBioconjugate ChemistryQ2343023
P1476titleXAV939: from a small inhibitor to a potent drug bioconjugate when delivered by gold nanoparticles
P478volume25

Reverse relations

cites work (P2860)
Q50068821Activation of PPARα by clofibrate sensitizes pancreatic cancer cells to radiation through the Wnt/β-catenin pathway
Q48692077Chemoradiotherapy Resistance in Colorectal Cancer Cells is Mediated by Wnt/β-catenin Signaling.
Q28077645Controlled actuation of therapeutic nanoparticles: an update on recent progress
Q33881254Future trends and emerging issues for nanodelivery systems in oral and oropharyngeal cancer
Q91658635Gene Expression Comparison between the Lymph Node-Positive and -Negative Reveals a Peculiar Immune Microenvironment Signature and a Theranostic Role for WNT Targeting in Pancreatic Ductal Adenocarcinoma: A Pilot Study
Q38797637Pre-clinical characterization of 4SC-202, a novel class I HDAC inhibitor, against colorectal cancer cells

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