review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1006/EXCR.1999.4695 |
P698 | PubMed publication ID | 10579920 |
P2093 | author name string | Bos JL | |
Zwartkruis FJ | |||
P2860 | cites work | Activation of the ERK/MAPK pathway by an isoform of rap1GAP associated with G alpha(i) | Q22010516 |
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 157-165 | |
P577 | publication date | 1999-11-01 | |
P1433 | published in | Experimental Cell Research | Q1524289 |
P1476 | title | Ras and Rap1: two highly related small GTPases with distinct function | |
P478 | volume | 253 |
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Q28211197 | A CalDAG-GEFI/Rap1/B-Raf cassette couples M(1) muscarinic acetylcholine receptors to the activation of ERK1/2 |
Q34577068 | Activation and function of the Rap1 GTPase in B lymphocytes |
Q28216348 | Activation of Ras/Erk pathway by a novel MET-interacting protein RanBPM |
Q57372155 | Activation of the Rap GTPases in B Lymphocytes Modulates B Cell Antigen Receptor-induced Activation of Akt but Has No Effect on MAPK Activation |
Q42824829 | C3G mediated suppression of malignant transformation involves activation of PP2A phosphatases at the subcortical actin cytoskeleton. |
Q40876374 | CalDAG-GEFIII activation of Ras, R-ras, and Rap1. |
Q28208774 | Characterisation of PDZ-GEFs, a family of guanine nucleotide exchange factors specific for Rap1 and Rap2 |
Q24302347 | Characterization of p87C3G, a novel, truncated C3G isoform that is overexpressed in chronic myeloid leukemia and interacts with Bcr-Abl |
Q46711244 | Coordinate regulation of forskolin-induced cellular proliferation in macrophages by protein kinase A/cAMP-response element-binding protein (CREB) and Epac1-Rap1 signaling: effects of silencing CREB gene expression on Akt activation |
Q39458220 | Coordinated regulation of Rap1 and thyroid differentiation by cyclic AMP and protein kinase A. |
Q30167857 | Crk family adaptors-signalling complex formation and biological roles |
Q89604978 | Cross-Talk in Nucleotide Signaling in Glioma C6 Cells |
Q28205761 | Crosstalk between cAMP and MAP kinase signaling in the regulation of cell proliferation |
Q34162513 | Cyclic AMP-independent involvement of Rap1/B-Raf in the angiotensin II AT2 receptor signaling pathway in NG108-15 cells |
Q39459257 | Cyclic AMP-mediated inhibition of cell growth requires the small G protein Rap1. |
Q44641792 | Depolarization-induced signaling to Ras, Rap1 and MAPKs in cortical neurons |
Q34189296 | Dictyostelium: an ideal organism for genetic dissection of Ras signalling networks. |
Q35046114 | Differential effects of P2Y1 and P2Y12 nucleotide receptors on ERK1/ERK2 and phosphatidylinositol 3-kinase signalling and cell proliferation in serum-deprived and nonstarved glioma C6 cells |
Q30168118 | Differential interaction of Cbl with Grb2 and CrkL in CD2-mediated NK cell activation |
Q28350048 | Dmrt1 expression is regulated by follicle-stimulating hormone and phorbol esters in postnatal Sertoli cells |
Q34325514 | Drosophila PDZ-GEF, a guanine nucleotide exchange factor for Rap1 GTPase, reveals a novel upstream regulatory mechanism in the mitogen-activated protein kinase signaling pathway |
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Q37125689 | Endothelial signaling in paracellular and transcellular leukocyte transmigration |
Q40600338 | Enhancement of migration and invasion of hepatoma cells via a Rho GTPase signaling pathway |
Q34792821 | Epac and PKA: a tale of two intracellular cAMP receptors |
Q40524023 | Epac- and Ca2+ -controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors |
Q40074070 | Essential role of Pyk2 and Src kinase activation in neuropeptide-induced proliferation of small cell lung cancer cells |
Q41769175 | Exoenzyme S shows selective ADP-ribosylation and GTPase-activating protein (GAP) activities towards small GTPases in vivo |
Q53349753 | Extracellular signal-regulated kinase-dependent proliferation is mediated through the protein kinase A/B-Raf pathway in human uveal melanoma cells. |
Q38698390 | Feedback regulation of G protein-coupled receptor signaling by GRKs and arrestins. |
Q34300201 | Focal adhesions require catalytic activity of Src family kinases to mediate integrin-matrix adhesion |
Q35096692 | GTPases and T cell activation |
Q36369648 | Gene expression profiling of B cell chronic lymphocytic leukemia reveals a homogeneous phenotype related to memory B cells. |
Q37858400 | Glycosides, depression and suicidal behaviour: the role of glycoside-linked proteins. |
Q28212652 | Guanine nucleotide exchange factors CalDAG-GEFI and CalDAG-GEFII are colocalized in striatal projection neurons |
Q28567778 | High glucose stimulates synthesis of fibronectin via a novel protein kinase C, Rap1b, and B-Raf signaling pathway |
Q41849600 | Hormonal regulation of phospholipase Cepsilon through distinct and overlapping pathways involving G12 and Ras family G-proteins |
Q33940377 | Identification of the mechanisms regulating the differential activation of the mapk cascade by epidermal growth factor and nerve growth factor in PC12 cells |
Q44270689 | Immunosuppressant FK506 induces neurite outgrowth in PC12 mutant cells with impaired NGF-promoted neuritogenesis via a novel MAP kinase signaling pathway |
Q35723724 | Impaired fertility and spermiogenetic disorders with loss of cell adhesion in male mice expressing an interfering Rap1 mutant |
Q37980724 | Inhibition and termination of physiological responses by GTPase activating proteins |
Q34623801 | Integration of calcium and Ras signalling. |
Q30164414 | Involvement of Crk Adapter Proteins in Regulation of Lymphoid Cell Functions |
Q39457285 | Lipopolysaccharide-induced activation of beta2-integrin function in macrophages requires Irak kinase activity, p38 mitogen- activated protein kinase, and the Rap1 GTPase |
Q22253953 | Mechanism of regulation of the Epac family of cAMP-dependent RapGEFs |
Q24545607 | Mechanism of the spatio-temporal regulation of Ras and Rap1. |
Q37417286 | Mechanisms of biphasic insulin-granule exocytosis - roles of the cytoskeleton, small GTPases and SNARE proteins |
Q43772601 | Nonisotopic methods for detecting activation of small G proteins |
Q38258281 | Of von Willebrand factor and platelets |
Q24804169 | Phosphorylated guanine nucleotide exchange factor C3G, induced by pervanadate and Src family kinases localizes to the Golgi and subcortical actin cytoskeleton |
Q37117611 | Phosphorylation of Rap1GAP, a striatally enriched protein, by protein kinase A controls Rap1 activity and dendritic spine morphology |
Q51060718 | Phosphorylation of the guanine-nucleotide-exchange factor CalDAG-GEFI by protein kinase A regulates Ca(2+)-dependent activation of platelet Rap1b GTPase. |
Q34534438 | Prospects for anti-ras drugs |
Q34988793 | Rap1 GTPase activation and barrier enhancement in rpe inhibits choroidal neovascularization in vivo |
Q41856499 | Rap1 activation plays a regulatory role in pancreatic amylase secretion. |
Q40835253 | Rap1 is activated by erythropoietin or interleukin-3 and is involved in regulation of beta1 integrin-mediated hematopoietic cell adhesion |
Q39587210 | Rap1 mediates galanin receptor 2-induced proliferation and survival in squamous cell carcinoma |
Q36322667 | Rap1 promotes cell spreading by localizing Rac guanine nucleotide exchange factors |
Q50335779 | Rap1 regulation of RIAM and cell adhesion. |
Q42166594 | Rap1A positively regulates T cells via integrin activation rather than inhibiting lymphocyte signaling |
Q34282328 | RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. |
Q34146651 | Ras and Rap control AMPA receptor trafficking during synaptic plasticity |
Q28345022 | Region-specific transcriptional response to chronic nicotine in rat brain |
Q28565555 | Regulation of dendritic spine morphology by SPAR, a PSD-95-associated RapGAP |
Q32065078 | Regulation of p42/p44 MAPK and p38 MAPK by the adenosine A(1) receptor in DDT(1)MF-2 cells. |
Q22253952 | Regulatory proteins of R-Ras, TC21/R-Ras2, and M-Ras/R-Ras3 |
Q28343294 | Requirement for C3G-dependent Rap1 activation for cell adhesion and embryogenesis |
Q43715902 | Requirement of Ras for the activation of mitogen-activated protein kinase by calcium influx, cAMP, and neurotrophin in hippocampal neurons. |
Q28266829 | Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors |
Q40756969 | Role for adapter proteins in costimulatory signals of CD2 and IL-2 on NK cell activation |
Q35168497 | Roles of 5'-AMP-activated protein kinase (AMPK) in mammalian glucose homoeostasis |
Q37257440 | SKAP-55, SKAP-55-related and ADAP adaptors modulate integrin-mediated immune-cell adhesion |
Q34331449 | Signal transduction via the growth hormone receptor |
Q36358082 | Signaling axis in schwann cell proliferation and differentiation |
Q37138723 | Small G proteins as key regulators of pancreatic digestive enzyme secretion. |
Q37068484 | Small G proteins exhibit pattern sensitivity in MAPK activation during the induction of memory and synaptic facilitation in Aplysia |
Q30168090 | T cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein |
Q30671262 | Temporal phases of activity-dependent plasticity and memory are mediated by compartmentalized routing of MAPK signaling in aplysia sensory neurons |
Q34618563 | The AF-6 Homolog Canoe Acts as a Rap1 Effector During Dorsal Closure of the Drosophila Embryo |
Q24683045 | The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain |
Q91579024 | The Mystery of Rap1 Suppression of Oncogenic Ras |
Q42213386 | The Small GTPase Rap1b: A Bidirectional Regulator of Platelet Adhesion Receptors |
Q79185264 | The effects of parathyroid hormone fragments on bone formation and their lack of effects on the initiation of colon carcinogenesis in rats as indicated by preneoplastic aberrant crypt formation |
Q37295364 | The interactome of the amyloid beta precursor protein family members is shaped by phosphorylation of their intracellular domains |
Q24671706 | The junctional multidomain protein AF-6 is a binding partner of the Rap1A GTPase and associates with the actin cytoskeletal regulator profilin |
Q44061979 | The role of cAMP-dependent signaling in receptor-recognized forms of alpha 2-macroglobulin-induced cellular proliferation |
Q30009350 | The small GTPase Rap1 promotes cell movement rather than stabilizes adhesion in epithelial cells responding to insulin-like growth factor I. |
Q33967880 | Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathways |
Q34572219 | Transgenic analysis of thymocyte signal transduction |
Q43571780 | cAMP and calcium ionophore induce outgrowth of neuronal processes in PC12 mutant cells in which nerve growth factor-induced outgrowth of neuronal processes is impaired |
Q34638723 | cAMP pathway in podocytes |
Q45032460 | cAMP-dependent oncogenic action of Rap1b in the thyroid gland |
Q33411711 | von Willebrand factor mutation promotes thrombocytopathy by inhibiting integrin αIIbβ3. |
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