Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun

scientific article published on May 1, 1998

Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/MCB.18.5.2815
P953full work available online athttp://mcb.asm.org/cgi/content/abstract/18/5/2815
https://europepmc.org/articles/PMC110660
https://europepmc.org/articles/pmc110660?pdf=render
https://europepmc.org/articles/PMC110660?pdf=render
https://journals.asm.org/doi/pdf/10.1128/MCB.18.5.2815
https://www.tandfonline.com/doi/pdf/10.1128/MCB.18.5.2815
P932PMC publication ID110660
P698PubMed publication ID9566900
P5875ResearchGate publication ID13713369

P2093author name stringR. Pope
M. Birrer
B. Thimmapaya
S. Ness
A. Zagariya
R. Lovis
S. Mungre
P2860cites workAmerican Journal of PhysiologyQ2160146
Enhanced IL-1 beta and tumor necrosis factor-alpha release and messenger RNA expression in macrophages from idiopathic pulmonary fibrosis or after asbestos exposureQ23923004
A nuclear factor for IL-6 expression (NF-IL6) is a member of a C/EBP familyQ24310416
Activation of cAMP and mitogen responsive genes relies on a common nuclear factorQ24313652
NF-IL6 and AP-1 cooperatively modulate the activation of the TSG-6 gene by tumor necrosis factor alpha and interleukin-1Q24609459
Interaction and functional collaboration of p300 and C/EBPβQ24644296
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin ResistanceQ28131660
Calcium-regulated phosphorylation within the leucine zipper of C/EBP betaQ28209974
Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritisQ28239197
Interaction of nuclear proteins with an AP-1/CRE-like promoter sequence in the human TNF-alpha geneQ28244716
Phosphorylated CREB binds specifically to the nuclear protein CBPQ28265019
Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cellsQ28276215
Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptorQ28286827
Macrophage differentiation-specific expression of NF-IL6, a transcription factor for interleukin-6Q28288190
Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factorQ28288345
Phosphorylation at threonine-235 by a ras-dependent mitogen-activated protein kinase cascade is essential for transcription factor NF-IL6Q28609813
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistanceQ29012156
The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factorQ31076639
Protein kinase A and C site-specific phosphorylations of LAP (NF-IL6) modulate its binding affinity to DNA recognition elementsQ34152141
C/EBP beta regulation of the tumor necrosis factor alpha geneQ34188989
The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipaseQ34216687
Expression of a tumor necrosis factor-alpha transgene in murine lung causes lymphocytic and fibrosing alveolitis. A mouse model of progressive pulmonary fibrosisQ35750477
The pathophysiology of tumor necrosis factorsQ36135208
Genetic analysis of the human tumor necrosis factor alpha/cachectin promoter region in a macrophage cell lineQ36356530
Identification of a novel cyclosporin-sensitive element in the human tumor necrosis factor alpha gene promoterQ36362429
Effect of tumor necrosis factor alpha on insulin-dependent diabetes mellitus in NOD mice. I. The early development of autoimmunity and the diabetogenic processQ36363681
Regulation of the pro-B-cell-specific enhancer of the Id1 gene involves the C/EBP family of proteinsQ36565352
Multiple Control Elements Mediate Activation of the Murine and Human Interleukin 12 p40 Promoters: Evidence of Functional Synergy between C/EBP and Rel ProteinsQ36570254
Fos and Jun repress transcription activation by NF-IL6 through association at the basic zipper regionQ36643268
Multiple forms of C/EBP beta bind the EFII enhancer sequence in the Rous sarcoma virus long terminal repeatQ36657531
Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interactionQ36689762
The transactivating domain of the c-Jun proto-oncoprotein is required for cotransformation of rat embryo cellsQ36744547
CRP2 (C/EBP beta) contains a bipartite regulatory domain that controls transcriptional activation, DNA binding and cell specificityQ37619789
Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcriptionQ38304818
C/EBP, NF-kappa B, and c-Ets family members and transcriptional regulation of the cell-specific and inducible macrophage inflammatory protein 1 alpha immediate-early geneQ38316488
Synergistic activation of the chicken mim-1 gene by v-myb and C/EBP transcription factors.Q38319512
Autocrine growth induced by kinase type oncogenes in myeloid cells requires AP-1 and NF-M, a myeloid specific, C/EBP-like factorQ38331502
Tumor necrosis factor alpha gene regulation in activated T cells involves ATF-2/Jun and NFATpQ40018125
Transcriptional induction of collagenase-1 in differentiated monocyte-like (U937) cells is regulated by AP-1 and an upstream C/EBP-beta siteQ41111005
Effect of 1-beta-D-arabinofuranosylcytosine on apoptosis and differentiation in human monocytic leukemia cells (U937) expressing a c-Jun dominant-negative mutant protein (TAM67).Q41201413
Autocrine regulation of collagenase gene expression by TNF-alpha in U937 cellsQ41255334
Regulation of the human TNF promoter by the transcription factor Ets.Q41358666
JNK is involved in signal integration during costimulation of T lymphocytes.Q41461688
Constitutive cJun expression induces partial macrophage differentiation in U-937 cellsQ41477513
Induction of tumor necrosis factor alpha production by human hepatocytes in chronic viral hepatitisQ41486203
Myb and NF-M: combinatorial activators of myeloid genes in heterologous cell typesQ41558201
The regulation of the human tumor necrosis factor alpha promoter region in macrophage, T cell, and B cell linesQ41594643
A nuclear factor for interleukin-6 expression (NF-IL6) and the glucocorticoid receptor synergistically activate transcription of the rat alpha 1-acid glycoprotein gene via direct protein-protein interactionQ42127094
Transactivation by NF-IL6/LAP is enhanced by phosphorylation of its activation domainQ43498366
Novel mechanism of C/EBP beta (NF-M) transcriptional control: activation through derepressionQ53014939
Suppression of oncogene-induced transformation by a deletion mutant of c-junQ53481195
Stimulation of c-Jun activity by CBP: c-Jun residues Ser63/73 are required for CBP induced stimulation in vivo and CBP binding in vitroQ57888777
Adenovirus E1A 13S gene product upregulates tumor necrosis factor geneQ64382881
Cyclosporin a modulation of tumor necrosis factor gene expression and effects in vitro and in vivoQ68457746
Analysis of IL-1 and TNF-alpha gene expression in human rheumatoid synoviocytes and normal monocytes by in situ hybridizationQ68632086
CCAAT/enhancer binding protein is involved in the expression of the tumour necrosis factor gene in human monocytesQ71311025
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectregulation of gene expressionQ411391
P304page(s)2815-2824
P577publication date1998-05-01
P1433published inMolecular and Cellular BiologyQ3319478
P1476titleTumor necrosis factor alpha gene regulation: enhancement of C/EBPbeta-induced activation by c-Jun
Tumor Necrosis Factor Alpha Gene Regulation: Enhancement of C/EBPβ-Induced Activation by c-Jun
P478volume18

Reverse relations

cites work (P2860)
Q447287275-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside inhibits proinflammatory response in glial cells: a possible role of AMP-activated protein kinase.
Q46366717A ceramide-1-phosphate analogue, PCERA-1, simultaneously suppresses tumour necrosis factor-alpha and induces interleukin-10 production in activated macrophages
Q36764540A novel polyamine analog inhibits growth and induces apoptosis in human breast cancer cells.
Q35747453Activator protein-1 activation in acute lung injury
Q40646180Adjacent sequence controls the response polarity of nitric oxide-sensitive Sp factor binding sites
Q33539762An NF-kappaB-dependent role for JunB in the induction of proinflammatory cytokines in LPS-activated bone marrow-derived dendritic cells
Q38669274Apoptosis Repressor with Caspase Recruitment Domain Ameliorates Amyloid-Induced β-Cell Apoptosis and JNK Pathway Activation.
Q33997219Arsenic carcinogenesis in the skin
Q59360479C6orf106 is a novel inhibitor of the interferon-regulatory factor 3-dependent innate antiviral response
Q37425262CCAAT/enhancer-binding proteins and the pathogenesis of retrovirus infection
Q40174568CEBPbeta, JunD and c-Jun contribute to the transcriptional activation of the metastasis-associated C4.4A gene.
Q22010670CHOP enhancement of gene transcription by interactions with Jun/Fos AP-1 complex proteins
Q34488816Calcineurin/nuclear factor of activated T cells and MAPK signaling induce TNF-{alpha} gene expression in pancreatic islet endocrine cells
Q39114351Chromatin loop organization of the junb locus in mouse dendritic cells
Q38083084Curcumin: an orally bioavailable blocker of TNF and other pro‐inflammatory biomarkers
Q47777739Cytokine expression in meconium-induced lungs
Q58181079Different Mitogen-activated Protein Kinase Signaling Pathways Cooperate to Regulate Tumor Necrosis Factor α Gene Expression in T Lymphocytes
Q43773093Dominant-negative TAK1 induces c-Myc and G0exit in liver
Q40955358Down-regulation of tumor necrosis factor alpha expression by activating transcription factor 2 increases UVC-induced apoptosis of late-stage melanoma cells
Q34443338Downregulation of c-Jun expression by transcription factor C/EBPalpha is critical for granulocytic lineage commitment
Q77983574Early activation of hepatic NFkappaB and NF-IL6 in polymicrobial sepsis correlates with bacteremia, cytokine expression, and mortality
Q43728690Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha
Q33999522Effects of calorie restriction on polymicrobial peritonitis induced by cecum ligation and puncture in young C57BL/6 mice
Q40811142Efficacy of adenoviral TNF alpha antisense is enhanced by a macrophage specific promoter.
Q33275849Ets-2 and C/EBP-beta are important mediators of ovine trophoblast Kunitz domain protein-1 gene expression in trophoblast
Q28374532FK506 prevents stroke-induced generation of ceramide and apoptosis signaling
Q34279351Function and regulation of AP-1 subunits in skin physiology and pathology
Q38313605Glucocorticoids suppress tumor necrosis factor-alpha expression by human monocytic THP-1 cells by suppressing transactivation through adjacent NF-kappa B and c-Jun-activating transcription factor-2 binding sites in the promoter
Q36629269High-mobility group box proteins modulate tumor necrosis factor-alpha expression in osteoclastogenesis via a novel deoxyribonucleic acid sequence
Q38294353Inhibitory role of TGIF in the As2O3-regulated p21 WAF1/CIP1 expression
Q40247529Interleukin-1beta and tetradecanoylphorbol acetate-induced biosynthesis of tumor necrosis factor alpha in human hepatoma cells involves the transcription factors ATF2 and c-Jun and stress-activated protein kinases
Q35671253Is there a future for TNF promoter polymorphisms?
Q35051206Macrophages and post-burn immune dysfunction
Q33870198Macrophages require constitutive NF-kappaB activation to maintain A1 expression and mitochondrial homeostasis
Q40931785Mechanistic aspects of green tea as a cancer preventive: effect of components on human stomach cancer cell lines
Q40876050Molecular mechanisms of tumor necrosis factor alpha gene expression in monocytic cells via hyperglycemia-induced oxidant stress-dependent and -independent pathways
Q34888292NF-kappa B-dependent assembly of an enhanceosome-like complex on the promoter region of apoptosis inhibitor Bfl-1/A1
Q64058915Natural Products and Obesity: A Focus on the Regulation of Mitotic Clonal Expansion during Adipogenesis
Q39329261Phospholipase C-δ1 regulates interleukin-1β and tumor necrosis factor-α mRNA expression
Q53215780Pretreatment of Rho Kinase Inhibitor Inhibits Systemic Inflammation and Prevents Endotoxin-Induced Acute Lung Injury in Mice
Q39135113Promoter identification and transcriptional regulation of the metastasis gene MACC1 in colorectal cancer
Q34984246Propolis augments apoptosis induced by butyrate via targeting cell survival pathways
Q38313106Prostaglandin E2 stimulates p53 transactivational activity through specific serine 15 phosphorylation in human synovial fibroblasts. Role in suppression of c/EBP/NF-kappaB-mediated MEKK1-induced MMP-1 expression
Q35177662Role of Jun and Jun kinase in resistance of cancer cells to therapy
Q45852576Sequence Characterization of S100A8 Gene Reveals Structural Differences of Protein and Transcriptional Factor Binding Sites in Water Buffalo and Yak
Q37767172TNFα in myocardial ischemia/reperfusion, remodeling and heart failure
Q37755216Targeting signaling pathways with small molecules to treat autoimmune disorders.
Q53398196The constitutive activation of the CEF-4/9E3 chemokine gene depends on C/EBPbeta in v-src transformed chicken embryo fibroblasts
Q37983666The macrophage response towards LPS and its control through the p38MAPK–STAT3 axis
Q37696067Transcriptional control of the TNF gene
Q30847471Woodchuck lymphotoxin-alpha, -beta and tumor necrosis factor genes: structure, characterization and biological activity
Q39676079c-Jun and hypoxia-inducible factor 1 functionally cooperate in hypoxia-induced gene transcription.

Search more.