review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | B Alex Merrick | |
Frank A Witzmann | |||
P2860 | cites work | Characterization of a stellate cell activation-associated protein (STAP) with peroxidase activity found in rat hepatic stellate cells | Q24291164 |
Absolute quantification of proteins and phosphoproteins from cell lysates by tandem MS | Q24680943 | ||
Discriminating different classes of toxicants by transcript profiling | Q24813403 | ||
Toxicoproteomics: a parallel approach to identifying biomarkers | Q24815922 | ||
Analyzing chromatin remodeling complexes using shotgun proteomics and normalized spectral abundance factors | Q27935763 | ||
The Her-2/neu gene and protein in breast cancer 2003: biomarker and target of therapy | Q28191663 | ||
Proteomic analysis of alternative protein tyrosine phosphorylation in 1,2-dichlorovinyl-cysteine-induced cytotoxicity in primary cultured rat renal proximal tubular cells | Q28573857 | ||
Proteomics profiling of nuclear proteins for kidney fibroblasts suggests hypoxia, meiosis, and cancer may meet in the nucleus | Q28576386 | ||
Toward the identification of liver toxicity markers: a proteome study in human cell culture and rats | Q28583284 | ||
Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants | Q28583445 | ||
Characterization of a gene encoding two isoforms of a mitochondrial protein up-regulated by cyclosporin A in activated T cells | Q28591382 | ||
In vivo effects of ozone exposure on protein adduct formation by 1-nitronaphthalene in rat lung | Q28752170 | ||
A model for random sampling and estimation of relative protein abundance in shotgun proteomics | Q29547316 | ||
Mass spectrometry as a diagnostic and a cancer biomarker discovery tool: opportunities and potential limitations | Q30751781 | ||
Mechanisms of hydrazine toxicity in rat liver investigated by proteomics and multivariate data analysis | Q30757712 | ||
Quantitative proteomic analysis of mouse liver response to the peroxisome proliferator diethylhexylphthalate (DEHP). | Q30761241 | ||
A mouse serum two-dimensional gel map: application to profiling burn injury and infection | Q30768000 | ||
An integrated proteomic approach to studying glomerular nephrotoxicity | Q30829397 | ||
Two-dimensional database of mouse liver proteins: changes in hepatic protein levels following treatment with acetaminophen or its nontoxic regioisomer 3-acetamidophenol | Q30885309 | ||
Role of biomarkers in identifying and understanding environmentally induced disease. | Q40662188 | ||
Renal and hepatic toxicity of trichloroethylene and its glutathione-derived metabolites in rats and mice: sex-, species-, and tissue-dependent differences. | Q43548284 | ||
Genomics and proteomics analysis of acetaminophen toxicity in mouse liver | Q43830368 | ||
Cyclosporine A-induced hypercalciuria in calbindin-D28k knockout and wild-type mice | Q44213005 | ||
Proteomic identification of potential susceptibility factors in drug-induced liver disease | Q44248240 | ||
Toxicogenomics of bromobenzene hepatotoxicity: a combined transcriptomics and proteomics approach | Q44356752 | ||
A correlation between a proteomic evaluation and conventional measurements in the assessment of renal proximal tubular toxicity | Q44376678 | ||
A potential biomarker of kidney damage identified by proteomics: preliminary findings | Q44565770 | ||
The pathogenic roles of tumor necrosis factor receptor p55 in acetaminophen-induced liver injury in mice | Q44616429 | ||
Early hepatic microvascular injury in response to acetaminophen toxicity | Q44616744 | ||
Proteomic analysis of phosphotyrosyl proteins in the rat brain: effect of butorphanol dependence | Q45034935 | ||
Key molecular events in puromycin aminonucleoside nephrosis rats | Q45055448 | ||
Mitochondrial permeability transition in acetaminophen-induced necrosis and apoptosis of cultured mouse hepatocytes | Q45108825 | ||
Innate immune system plays a critical role in determining the progression and severity of acetaminophen hepatotoxicity | Q45172577 | ||
The absolute quantification strategy: a general procedure for the quantification of proteins and post-translational modifications | Q45275572 | ||
A functional annotation of subproteomes in human plasma | Q46404977 | ||
Investigation of a hepatotoxicity screening system in primary cell cultures --"what biomarkers would need to be addressed to estimate toxicity in conventional and new approaches?". | Q46412881 | ||
Heat shock protein 27 is the major differentially phosphorylated protein involved in renal epithelial cellular stress response and controls focal adhesion organization and apoptosis | Q46535306 | ||
Comparison of label-free methods for quantifying human proteins by shotgun proteomics. | Q46568113 | ||
Isolation of rodent airway epithelial cell proteins facilitates in vivo proteomics studies of lung toxicity. | Q46633445 | ||
Proteomic analysis of proliferation and apoptosis in carbon tetrachloride induced rat liver fibrosis | Q46644081 | ||
Use of proteomic methods to identify serum biomarkers associated with rat liver toxicity or hypertrophy. | Q46650091 | ||
Identification of oxidative stress-related proteins for predictive screening of hepatotoxicity using a proteomic approach | Q46686559 | ||
Modulation of cytochrome C oxidase-va is possibly involved in metallothionein protection from doxorubicin cardiotoxicity | Q46689521 | ||
Saturation toxicokinetics of thioacetamide: role in initiation of liver injury | Q46720495 | ||
Reduction of cisplatin toxicity in cultured renal tubular cells by the bioflavonoid quercetin. | Q50522380 | ||
Statistical Analysis of Membrane Proteome Expression Changes inSaccharomycescerevisiae | Q57997776 | ||
Reference maps of mouse serum acute-phase proteins: Changes with LPS-induced inflammation and apolipoprotein A-I and A-II transgenes | Q58475257 | ||
Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells | Q68784186 | ||
Cyclosporine A decreases the protein level of the calcium-binding protein calbindin-D 28kDa in rat kidney | Q70929382 | ||
Effects of cyclosporine A on the rat liver and kidney protein pattern, and the influence of vitamin E and C coadministration | Q71583100 | ||
Compounds protective against renal tubular necrosis induced by D-serine and D-2,3-diaminopropionic acid in the rat | Q71628599 | ||
Proteomic analysis of rat kidney cortex following treatment with gentamicin | Q73142320 | ||
SELDI-TOF MS for diagnostic proteomics | Q73296199 | ||
Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment | Q73322671 | ||
Adaptation of protein carbonyl detection to the requirements of proteome analysis demonstrated for hypoxia/reoxygenation in isolated rat liver mitochondria | Q73575366 | ||
Proteome analysis of rat hepatic stellate cells | Q74071343 | ||
Increased protein synthesis after T cell activation in presence of cyclosporin A | Q74136644 | ||
Drug-induced liver injury | Q76383956 | ||
Regional protein alterations in rat kidneys induced by lead exposure | Q77799032 | ||
Proteomic Identification of a Large Complement of Rat Urinary Proteins | Q79279992 | ||
Proteomics of S-(1, 2-dichlorovinyl)-L-cysteine-induced acute renal failure and autoprotection in mice | Q80506973 | ||
A multiple reaction monitoring method for absolute quantification of the human liver alcohol dehydrogenase ADH1C1 isoenzyme | Q80782092 | ||
Comprehensive label-free method for the relative quantification of proteins from biological samples | Q81012916 | ||
Differential proteomics via probabilistic peptide identification scores | Q81267882 | ||
Joint EFPIA/CHMP SWP workshop: the Emerging Use of Omic Technologies for Regulatory Non-Clinical Safety Testing | Q81728686 | ||
Searching for potential biomarkers of cisplatin resistance in human ovarian cancer using a label-free LC/MS-based protein quantification method | Q82774331 | ||
Combination of 'omics' data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in rats and to identify potential biomarkers | Q30959523 | ||
Chemical effects in biological systems--data dictionary (CEBS-DD): a compendium of terms for the capture and integration of biological study design description, conventional phenotypes, and 'omics data | Q31003916 | ||
Molecular classification of liver cirrhosis in a rat model by proteomics and bioinformatics | Q31113677 | ||
A proteomic analysis of thioacetamide-induced hepatotoxicity and cirrhosis in rat livers | Q31125597 | ||
Changes in global gene and protein expression during early mouse liver carcinogenesis induced by non-genotoxic model carcinogens oxazepam and Wyeth-14,643. | Q31141170 | ||
Differential expression of cytosolic proteins in the rat kidney cortex and medulla: preliminary proteomics | Q31973032 | ||
Optimization of reversed-phase microcapillary liquid chromatography for quantitative proteomics | Q33199691 | ||
Clinical proteomics: revolutionizing disease detection and patient tailoring therapy | Q33202393 | ||
Toxicoproteomics: serum proteomic pattern diagnostics for early detection of drug induced cardiac toxicities and cardioprotection | Q33204056 | ||
Characterization of the secreted proteome of rat hepatocytes cultured in collagen sandwiches | Q33219624 | ||
Novel mass spectrometric methods for evaluation of plasma angiotensin converting enzyme 1 and renin activity | Q33221785 | ||
Overview of the HUPO Plasma Proteome Project: results from the pilot phase with 35 collaborating laboratories and multiple analytical groups, generating a core dataset of 3020 proteins and a publicly-available database | Q33221802 | ||
Robust enrichment of phosphorylated species in complex mixtures by sequential protein and peptide metal-affinity chromatography and analysis by tandem mass spectrometry. | Q33222165 | ||
Immunodepletion of albumin for two-dimensional gel detection of new mouse acute-phase protein and other plasma proteins | Q33222559 | ||
Effects of formaldehyde inhalation on lung of rats | Q33222574 | ||
Proteomics in renal research | Q33263714 | ||
Comparison of the specificity and sensitivity of traditional methods for assessment of nephrotoxicity in the rat with metabonomic and proteomic methodologies | Q33390018 | ||
Quantitation of acrolein-derived (3-hydroxypropyl)mercapturic acid in human urine by liquid chromatography-atmospheric pressure chemical ionization tandem mass spectrometry: effects of cigarette smoking | Q33437470 | ||
Validation and development of fluorescence two-dimensional differential gel electrophoresis proteomics technology | Q34099409 | ||
Role of macrophages and inflammatory mediators in chemically induced toxicity | Q34179549 | ||
The role of metabolic activation in drug-induced hepatotoxicity | Q34410432 | ||
Therapeutic roles of peroxisome proliferator-activated receptor agonists | Q34437323 | ||
Toxicoproteomics -- a new preclinical tool | Q34578614 | ||
Monitoring the effects of drug treatment in rat models of disease by serum protein analysis | Q34642368 | ||
A label-free quantification method by MS/MS TIC compared to SILAC and spectral counting in a proteomics screen | Q34759490 | ||
A toxicologist's guide to biomarkers of hepatic response | Q34761550 | ||
Protein arrays: the current state-of-the-art | Q35053985 | ||
Hepatotoxicity and Mechanism of Action of Haloalkanes: Carbon Tetrachloride as a Toxicological Model | Q35112180 | ||
Markers of genetic susceptibility in human environmental hygiene and toxicology: the role of selected CYP, NAT and GST genes. | Q35181964 | ||
Quantitative proteomic analysis of distinct mammalian Mediator complexes using normalized spectral abundance factors | Q35182494 | ||
The future of regulatory toxicology: impact of the biotechnology revolution | Q35185853 | ||
Proteomics and nephrotoxicity. | Q35598018 | ||
Transplantation: toxicokinetics and mechanisms of toxicity of cyclosporine and macrolides. | Q35647093 | ||
Mass spectral analysis in proteomics | Q35771577 | ||
Proteomics for protein expression profiling in neuroscience | Q35791534 | ||
Pharmacoproteomic approach to the study of drug mode of action, toxicity, and resistance: applications in diabetes and cancer | Q35863384 | ||
Proteomic approaches in brain research and neuropharmacology | Q35908585 | ||
Critical survey of quantitative proteomics in two-dimensional electrophoretic approaches. | Q35942807 | ||
Cell biology, chemogenomics and chemoproteomics | Q35962670 | ||
Toxicogenomics and systems toxicology: aims and prospects | Q35968452 | ||
Toxicoproteomics: proteomics applied to toxicology and pathology | Q35973576 | ||
Genomic and proteomic profiling for biomarkers and signature profiles of toxicity. | Q36016582 | ||
Unraveling kinase signaling pathways with chemical genetic and chemical proteomic approaches | Q36041806 | ||
The agony and ecstasy of "OMIC" technologies in drug development | Q36048330 | ||
Drug-induced hepatotoxicity: 2005. | Q36066824 | ||
Combinatorial biomarkers: From early toxicology assays to patient population profiling | Q36143394 | ||
A comprehensive listing of bioactivation pathways of organic functional groups | Q36173107 | ||
Complementary gene and protein expression studies and integrative approaches in toxicogenomics | Q36181783 | ||
Extracting meaning from functional genomics experiments | Q36185747 | ||
Application of emerging technologies in toxicology and safety assessment: regulatory perspectives | Q36205652 | ||
Introduction to the Food and Drug Administration (FDA) regulatory process | Q36219595 | ||
Drug-associated mitochondrial toxicity and its detection | Q36230338 | ||
Stable isotopes, mass spectrometry, and molecular fluxes: applications to toxicology | Q36280959 | ||
High-sensitivity C-reactive protein as a risk assessment tool for cardiovascular disease. | Q36297402 | ||
Pharmacogenomics and cardiovascular drugs: need for integrated biological system with phenotypes and proteomic markers | Q36326419 | ||
2D gel blood serum biomarkers reveal differential clinical proteomics of the neurodegenerative diseases | Q36381232 | ||
Pharmacogenomics and clinical biomarkers in drug discovery and development | Q36391992 | ||
Probabilistic assembly of human protein interaction networks from label-free quantitative proteomics | Q36446314 | ||
Genomic-based biomarkers of drug-induced nephrotoxicity | Q36545044 | ||
Systems biology approach to integrative comparative genomics | Q36731395 | ||
Hepatic gene expression and lipid homeostasis in C57BL/6 mice exposed to hydrazine or acetylhydrazine | Q38338365 | ||
Hepatic protein expression of lean mice and obese diabetic mice treated with peroxisome proliferator-activated receptor activators. | Q38355764 | ||
Cyclosporin A: action and side-effects | Q38616221 | ||
The nephrotoxicity of p-aminophenol. I. The effect on microsomal cytochromes, glutathione and covalent binding in kidney and liver | Q39693292 | ||
Tumor Necrosis Factor-alpha- and interleukin-1-induced cellular responses: coupling proteomic and genomic information | Q40132752 | ||
Comparative plasma proteome analysis of lymphoma-bearing SJL mice | Q40364333 | ||
Cytokines and toxicity in acetaminophen overdose | Q40387774 | ||
Use of a fluorescent phosphoprotein dye to characterize oxidative stress-induced signaling pathway components in macrophage and epithelial cultures exposed to diesel exhaust particle chemicals | Q40425153 | ||
Biomarker discovery in biological fluids | Q40444334 | ||
Mechanisms of the Formation and Disposition of Reactive Metabolites That can Cause Acute Liver Injury | Q40463530 | ||
Systems biology and new technologies enable predictive and preventative medicine. | Q40473946 | ||
P304 | page(s) | 367-400 | |
P577 | publication date | 2009-01-01 | |
P1433 | published in | EXS | Q27709924 |
P1476 | title | The role of toxicoproteomics in assessing organ specific toxicity | |
P478 | volume | 99 |
Q47641539 | An investigation of methyl tert‑butyl ether‑induced cytotoxicity and protein profile in Chinese hamster ovary cells |
Q36287496 | Increased liver-specific proteins in circulating extracellular vesicles as potential biomarkers for drug- and alcohol-induced liver injury |
Q33936338 | Proteomic alterations in mouse kidney induced by andrographolide sodium bisulfite |
Q34796767 | Proteomic analysis of kidney in rats chronically exposed to monosodium glutamate |
Q38266035 | Proteomics for systems toxicology |
Q37767386 | The future of toxicity testing |
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