Cryptococcus gattii virulence composite: candidate genes revealed by microarray analysis of high and less virulent Vancouver island outbreak strains

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Cryptococcus gattii virulence composite: candidate genes revealed by microarray analysis of high and less virulent Vancouver island outbreak strains is …
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P819ADS bibcode2011PLoSO...616076N
P356DOI10.1371/JOURNAL.PONE.0016076
P932PMC publication ID3020960
P698PubMed publication ID21249145
P5875ResearchGate publication ID49768910

P50authorPopchai NgamskulrungrojQ59695826
John R PerfectQ64932411
Wieland MeyerQ36702877
Tania SorrellQ37839159
P2093author name stringJennifer Price
P2860cites workCell wall assembly in Saccharomyces cerevisiaeQ24549234
A rare genotype of Cryptococcus gattii caused the cryptococcosis outbreak on Vancouver Island (British Columbia, Canada)Q24558831
Spread of Cryptococcus gattii in British Columbia, Canada, and detection in the Pacific Northwest, USAQ24652835
Two sporulation-specific chitin deacetylase-encoding genes are required for the ascospore wall rigidity of Saccharomyces cerevisiaeQ27932891
The glyoxylate cycle is required for fungal virulenceQ28206225
The fatal fungal outbreak on Vancouver Island is characterized by enhanced intracellular parasitism driven by mitochondrial regulationQ28253787
A New Species of Filobasidiella, the Sexual State of Cryptococcus neoformans B and C SerotypesQ30052289
Characterization of Cryptococcus neoformans variety gattii SOD2 reveals distinct roles of the two superoxide dismutases in fungal biology and virulenceQ33212634
Yeast beta-glucan synthesis: KRE6 encodes a predicted type II membrane protein required for glucan synthesis in vivo and for glucan synthase activity in vitroQ33326054
The trehalose synthesis pathway is an integral part of the virulence composite for Cryptococcus gattiiQ33490038
Cas3p belongs to a seven-member family of capsule structure designer proteinsQ33560210
Emergence and pathogenicity of highly virulent Cryptococcus gattii genotypes in the northwest United StatesQ33565424
Molecular typing of Cryptococcus neoformans: taxonomic and epidemiological aspectsQ38558615
Recapitulation of the sexual cycle of the primary fungal pathogen Cryptococcus neoformans var. gattii: implications for an outbreak on Vancouver Island, CanadaQ39011044
Epidemiologic differences between the two varieties of Cryptococcus neoformansQ39154213
Gene transfer in Cryptococcus neoformans by use of biolistic delivery of DNAQ39885245
Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans.Q40384960
Biochemical and physiological effects of sterol alterations in yeast--a reviewQ40550822
Multispecies outbreak of cryptococcosis on southern Vancouver Island, British Columbia.Q40560602
Transcription factor STE12alpha has distinct roles in morphogenesis, virulence, and ecological fitness of the primary pathogenic yeast Cryptococcus gattiiQ41487634
Divergence of protein kinase A catalytic subunits in Cryptococcus neoformans and Cryptococcus gattii illustrates evolutionary reconfiguration of a signaling cascadeQ41878122
Cryptococcal phospholipases: a novel lysophospholipase discovered in the pathogenic fungus Cryptococcus gattiiQ41895204
Isolation and characterisation of the phospholipase B gene of Cryptococcus neoformans var. gattiiQ42597540
Fatty acid synthesis is essential for survival of Cryptococcus neoformans and a potential fungicidal targetQ42627763
Cryptococcus neoformans variety gattiiQ44136176
Isolation of a CDC28 homologue from Cryptococcus neoformans that is able to complement cdc28 temperature-sensitive mutants of Saccharomyces cerevisiae.Q44849074
A H2O2-producing glyoxal oxidase is required for filamentous growth and pathogenicity in Ustilago maydisQ45172398
The CRH family coding for cell wall glycosylphosphatidylinositol proteins with a predicted transglycosidase domain affects cell wall organization and virulence of Candida albicans.Q46200244
Characterization of B-type cyclins in the smut fungus Ustilago maydis: roles in morphogenesis and pathogenicity.Q47315711
Taxonomic studies on Filobasidiella species and their anamorphs.Q50716596
Regional pattern of the molecular types of Cryptococcus neoformans and Cryptococcus gattii in Brazil.Q54515631
Same-sex mating and the origin of the Vancouver Island Cryptococcus gattii outbreakQ57255677
Novel gene functions required for melanization of the human pathogenCryptococcus neoformansQ58023611
Global VGIIa isolates are of comparable virulence to the major fatal Cryptococcus gattii Vancouver Island outbreak genotypeQ58034853
Association between fertility and molecular sub-type of global isolates ofCryptococcus gattiimolecular type VGIIQ58034914
Molecular epidemiology of clinical and environmental isolates of theCryptococcus neoformansspecies complex reveals a high genetic diversity and the presence of the molecular type VGII mating type a in ColombiaQ58034938
Signal transduction pathways regulating differentiation and pathogenicity of Cryptococcus neoformansQ62845835
Reduction of the in vivo virulence of Candida albicans by pretreatment with subinhibitory azole concentrations in vitroQ70412755
Epidemiology of cryptococcosis in France: a 9-year survey (1985-1993). French Cryptococcosis Study GroupQ71554754
Genome-wide analysis of gene expression regulated by the yeast cell wall integrity signalling pathwayQ73265537
First report of Cryptococcus neoformans var. gattii serotype B from GreeceQ74257930
Molecular analysis of 311 Cryptococcus neoformans isolates from a 30-month ECMM survey of cryptococcosis in EuropeQ83332740
Transcriptional network of multiple capsule and melanin genes governed by the Cryptococcus neoformans cyclic AMP cascadeQ33719196
Urease as a virulence factor in experimental cryptococcosisQ33886908
Molecular analysis of CPRalpha, a MATalpha-specific pheromone receptor gene of Cryptococcus neoformansQ33904315
Detection and identification of fungal pathogens by PCR and by ITS2 and 5.8S ribosomal DNA typing in ocular infectionsQ33973144
Amphotericin B and fluconazole affect cellular charge, macrophage phagocytosis, and cellular morphology of Cryptococcus neoformans at subinhibitory concentrationsQ33975989
Molecular typing of IberoAmerican Cryptococcus neoformans isolatesQ33984407
Exploration of whole-genome responses of the human AIDS-associated yeast pathogen Cryptococcus neoformans var grubii: nitric oxide stress and body temperature.Q34005390
Comparative gene genealogies indicate that two clonal lineages of Cryptococcus gattii in British Columbia resemble strains from other geographical areas.Q34097624
Genetics of Ustilago maydis, a fungal pathogen that induces tumors in maizeQ34399178
Superoxide dismutase influences the virulence of Cryptococcus neoformans by affecting growth within macrophagesQ34532068
Virulence of Cryptococcus neoformans. Regulation of capsule synthesis by carbon dioxideQ34547882
Transcription factor Nrg1 mediates capsule formation, stress response, and pathogenesis in Cryptococcus neoformans.Q34718557
Genetics of Cryptococcus neoformansQ34995484
Sterols in microorganismsQ35048964
The Cryptococcus neoformans MAP kinase Mpk1 regulates cell integrity in response to antifungal drugs and loss of calcineurin functionQ35128586
Peroxisome function regulates growth on glucose in the basidiomycete fungus Cryptococcus neoformansQ35641052
Fungal cell wall chitinases and glucanasesQ35837894
Biochemical and molecular characterization of the diphenol oxidase of Cryptococcus neoformans: identification as a laccaseQ36105023
Cryptococcus neoformans: a sugar-coated killer with designer genesQ36213349
Cell-cycle control of gene expression in budding and fission yeastQ36312193
Induction of Capsule Growth inCryptococcus neoformansby Mammalian Serum and CO2Q36376167
Lipid metabolism in Cryptococcus neoformansQ36476667
Antifungal agents: mode of action in yeast cellsQ36590496
Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulenceQ36657718
Genetic association of mating types and virulence in Cryptococcus neoformansQ36958159
Cryptococcus gattii: Emergence in Western North America: Exploitation of a Novel Ecological Niche.Q37111315
Cryptococcus gattii isolates from the British Columbia cryptococcosis outbreak induce less protective inflammation in a murine model of infection than Cryptococcus neoformansQ37355898
Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarrayQ37579804
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectCryptococcus gattiiQ149791
P304page(s)e16076
P577publication date2011-01-13
P1433published inPLOS OneQ564954
P1476titleCryptococcus gattii virulence composite: candidate genes revealed by microarray analysis of high and less virulent Vancouver island outbreak strains
P478volume6

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