Nanosizing of a poorly soluble drug: technique optimization, factorial analysis, and pharmacokinetic study in healthy human volunteers.

scientific article

Nanosizing of a poorly soluble drug: technique optimization, factorial analysis, and pharmacokinetic study in healthy human volunteers. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2147/IJN.S63395
P932PMC publication ID4069131
P698PubMed publication ID24971006
P5875ResearchGate publication ID263513744

P50authorIbrahim ElsayedQ57053266
P2093author name stringAhmed Hassen Elshafeey
Aly Ahmed Abdelbary
P2860cites workWorld Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjectsQ28300546
Buparvaquone mucoadhesive nanosuspension: preparation, optimisation and long-term stabilityQ30832367
Selection of reliable reference genes for qPCR studies on chondroprotective actionQ33275599
Development of an oral rutin nanocrystal formulationQ33396383
Modeling and comparison of dissolution profilesQ34215811
Nanosuspensions: a promising drug delivery strategy.Q35826447
Nanosuspensions in drug deliveryQ35876031
Effect of particle size on solubility, dissolution rate, and oral bioavailability: evaluation using coenzyme Q₁₀ as naked nanocrystalsQ36404933
Nanosizing--oral formulation development and biopharmaceutical evaluationQ36865278
A novel preparation method for drug nanocrystals and characterization by ultrasonic spray-assisted electrostatic adsorptionQ37233330
Top-down production of drug nanocrystals: nanosuspension stabilization, miniaturization and transformation into solid products.Q37249988
Nanocrystal technology, drug delivery and clinical applications.Q37319937
Development of lipid nanoparticles of diacerein, an antiosteoarthritic drug for enhancement in bioavailability and reduction in its side effectsQ39224874
Optimization of pellets containing solid dispersion prepared by extrusion/spheronization using central composite design and desirability functionQ41650065
Risperidone solid dispersion for orally disintegrating tablet: its formulation design and non-destructive methods of evaluationQ42923477
Comparison of nanomilling and coprecipitation on the enhancement of in vitro dissolution rate of poorly water-soluble model drug aripiprazoleQ44639623
Enhancing the bioavailability of ABT-963 using solid dispersion containing Pluronic F-68.Q45121177
Preparation of hydrocortisone nanosuspension through a bottom-up nanoprecipitation technique using microfluidic reactors.Q45989955
Advantages of celecoxib nanosuspension formulation and transformation into tablets.Q46019773
Solubility increases associated with crystalline drug nanoparticles: methodologies and significanceQ46188911
Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipineQ46582675
Preparation and characterization of an oridonin nanosuspension for solubility and dissolution velocity enhancementQ46837639
Influence of experimental parameters on the characteristics of poly(lactic acid) nanoparticles prepared by a double emulsion methodQ47758963
Statistical optimization of medium components and growth conditions by response surface methodology to enhance phenol degradation by Pseudomonas putida.Q50959372
Third international conference on harmonization of technical requirements for registration of pharmaceuticals for human use--a toxicologist's perspective.Q53366676
A screening study of surface stabilization during the production of drug nanocrystalsQ59285630
Production and characterisation of highly concentrated nanosuspensions by high pressure homogenisationQ73701609
Micronization: a method of improving the bioavailability of poorly soluble drugsQ74727268
Clinical pharmacokinetics of diacereinQ77634758
Dissolution rate studies. II. Dissolution of particles under conditions of rapid agitationQ79452313
Physicochemical characterization and dissolution study of solid dispersions of diacerein with polyethylene glycol 6000Q83748227
Enhanced dissolution and oral bioavailability of aripiprazole nanosuspensions prepared by nanoprecipitation/homogenization based on acid-base neutralizationQ84991817
Effect of fixed aqueous layer thickness of polymeric stabilizers on zeta potential and stability of aripiprazole nanosuspensionsQ87407226
P275copyright licenseCreative Commons Attribution-NonCommercial 3.0 UnportedQ18810331
P6216copyright statuscopyrightedQ50423863
P407language of work or nameEnglishQ1860
P921main subjectpharmacokineticsQ323936
P304page(s)2943-2953
P577publication date2014-06-17
P1433published inInternational Journal of NanomedicineQ6051502
P1476titleNanosizing of a poorly soluble drug: technique optimization, factorial analysis, and pharmacokinetic study in healthy human volunteers
P478volume9

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cites work (P2860)
Q37527859A quality by design approach on polymeric nanocarrier delivery of gefitinib: formulation, in vitro, and in vivo characterization.
Q38661401A top-down technique to improve the solubility and bioavailability of aceclofenac: in vitro and in vivo studies.
Q42204107Are We Using Slow-Acting Symptomatic Chondroprotective Drugs Conscious Enough?
Q64984261Bioavailability Enhancement of Poorly Water-Soluble Drugs via Nanocomposites: Formulation⁻Processing Aspects and Challenges.
Q40970686Chitosan-coated diacerein nanosuspensions as a platform for enhancing bioavailability and lowering side effects: preparation, characterization, and ex vivo/in vivo evaluation
Q48105405Enhancement of pharmacokinetic and pharmacological behavior of ocular dorzolamide after factorial optimization of self-assembled nanostructures.
Q52647214Fabrication of novel elastosomes for boosting the transdermal delivery of diacerein: statistical optimization, ex-vivo permeation, in-vivo skin deposition and pharmacokinetic assessment compared to oral formulation.
Q64972547Implementing Central Composite Design for Developing Transdermal Diacerein-Loaded Niosomes: Ex vivo Permeation and In vivo Deposition.
Q58738523Oleic Acid Nanovesicles of Minoxidil for Enhanced Follicular Delivery
Q89909601Optimization, characterization and in vitro/vivo evaluation of azilsartan nanocrystals
Q49874284Preparation and evaluation of PCL-PEG-PCL micelles as potential nanocarriers for ocular delivery of dexamethasone
Q43216548Preparation, optimization, and in vitro simulated inhalation delivery of carvedilol nanoparticles loaded on a coarse carrier intended for pulmonary administration
Q58698851Self-nanoemulsifying drug-delivery systems for potentiated anti-inflammatory activity of diacerein
Q64087626Use of transethosomes for enhancing the transdermal delivery of olmesartan medoxomil: in vitro, ex vivo, and in vivo evaluation

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