The large delta antigen of hepatitis delta virus potently inhibits genomic but not antigenomic RNA synthesis: a mechanism enabling initiation of viral replication

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The large delta antigen of hepatitis delta virus potently inhibits genomic but not antigenomic RNA synthesis: a mechanism enabling initiation of viral replication is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.74.16.7375-7380.2000
P932PMC publication ID112257
P698PubMed publication ID10906190

P2093author name stringM M Lai
L E Modahl
P2860cites workSingle-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform ExtractionQ25938986
A specific base transition occurs on replicating hepatitis delta virus RNAQ28276497
A bacteriophage T7 RNA polymerase/promoter system for controlled exclusive expression of specific genesQ29547324
Growth of human hepatoma cells lines with differentiated functions in chemically defined mediumQ29617962
Transcription of hepatitis delta antigen mRNA continues throughout hepatitis delta virus (HDV) replication: a new model of HDV RNA transcription and replicationQ33784917
Assembly of hepatitis delta virus particlesQ33932270
RNA-Dependent replication and transcription of hepatitis delta virus RNA involve distinct cellular RNA polymerasesQ33965067
Hepatitis delta virus RNA editing is highly specific for the amber/W site and is suppressed by hepatitis delta antigenQ33994301
Hepatitis delta virus: protein composition of delta antigen and its hepatitis B virus-derived envelope.Q34050505
Molecular cloning and sequencing of a human hepatitis delta (delta) virus RNA.Q34186049
A pseudoknot ribozyme structure is active in vivo and required for hepatitis delta virus RNA replicationQ35858952
Isoprenylation masks a conformational epitope and enhances trans-dominant inhibitory function of the large hepatitis delta antigenQ36633321
Packaging of hepatitis delta virus RNA via the RNA-binding domain of hepatitis delta antigens: different roles for the small and large delta antigens.Q36636013
Ribonucleoprotein complexes of hepatitis delta virus.Q36647583
Oligomerization of hepatitis delta antigen is required for both the trans-activating and trans-dominant inhibitory activities of the delta antigenQ36685289
Role of two forms of hepatitis delta virus antigen: evidence for a mechanism of self-limiting genome replicationQ36784241
Initiation of replication of the human hepatitis delta virus genome from cloned DNA: role of delta antigenQ36827216
Regulation of polyadenylation of hepatitis delta virus antigenomic RNAQ36827823
Interaction between Kb and Q4 gene sequences generates the Kbm6 mutationQ36910005
Polyadenylation of the mRNA of hepatitis delta virus is dependent on the structure of the nascent RNA and regulated by the small or large delta antigenQ37585927
The large form of hepatitis delta antigen is crucial for assembly of hepatitis delta virusQ37597959
Hepatitis delta antigen mediates the nuclear import of hepatitis delta virus RNA.Q39578229
Genotype-specific complementation of hepatitis delta virus RNA replication by hepatitis delta antigen.Q39578987
Isoprenylation mediates direct protein-protein interactions between hepatitis large delta antigen and hepatitis B virus surface antigen.Q40048765
trans-dominant inhibition of human hepatitis delta virus genome replicationQ40062945
The molecular biology of hepatitis delta virusQ40421998
Characterization of mRNA for hepatitis delta antigen: exclusion of the full-length antigenomic RNA as an mRNA.Q41003023
Identification of the functional regions required for hepatitis D virus replication and transcription by linker-scanning mutagenesis of viral genomeQ41071965
RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminaseQ41206734
Promoter-selective transcriptional defect in cell cycle mutant ts13 rescued by hTAFII250.Q41487995
A unique conformation at the carboxyl terminus of the small hepatitis delta antigen revealed by a specific monoclonal antibodyQ41562285
Inhibition of Cellular RNA polymerase II transcription by delta antigen of hepatitis delta virusQ42459935
Characterization of a new genotype II hepatitis delta virus from TaiwanQ42647849
Antigens of hepatitis delta virus in the liver and serum of humans and animalsQ45829626
A human monoclonal antibody that recognizes viral polypeptides and in vitro translation products of the genome of the hepatitis D virusQ45847931
P433issue16
P921main subjecthepatitis delta virusQ1607636
P304page(s)7375-7380
P577publication date2000-08-01
P1433published inJournal of VirologyQ1251128
P1476titleThe large delta antigen of hepatitis delta virus potently inhibits genomic but not antigenomic RNA synthesis: a mechanism enabling initiation of viral replication
P478volume74

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cites work (P2860)
Q64266123A review on hepatitis D: From virology to new therapies
Q30485092An overview of triple infection with hepatitis B, C and D viruses
Q24564116By inhibiting replication, the large hepatitis delta antigen can indirectly regulate amber/W editing and its own expression
Q39683279Genomic but not antigenomic hepatitis delta virus RNA is preferentially exported from the nucleus immediately after synthesis and processing
Q26775635Hepatitis B and Delta Virus: Advances on Studies about Interactions between the Two Viruses and the Infected Hepatocyte
Q36891082Hepatitis Delta Virus RNA Encoding the Large Delta Antigen Cannot Sustain Replication due to Rapid Accumulation of Mutations Associated with RNA Editing
Q40274405Hepatitis delta virus antigen is methylated at arginine residues, and methylation regulates subcellular localization and RNA replication
Q33967322High prevalence of hepatitis delta virus among patients with chronic hepatitis B virus infection and HIV-1 in an intermediate hepatitis B virus endemic region.
Q36509331Interaction and replication activation of genotype I and II hepatitis delta antigens
Q39684855Large hepatitis delta antigen is not a suppressor of hepatitis delta virus RNA synthesis once RNA replication is established
Q36765645Molecular epidemiology of hepatitis D virus circulating in Southwestern Nigeria.
Q34740997Molecular epidemiology of hepatitis D virus infection among injecting drug users with and without human immunodeficiency virus infection in Taiwan
Q40245846Molecular interactions between hepatitis B virus and delta virus
Q36163276RNA replication without RNA-dependent RNA polymerase: surprises from hepatitis delta virus
Q45392641Role of hepatitis B virus, hepatitis D virus and other determinants on suppression of hepatitis C viraemia in HIV infected patients with chronic HCV infection: a longitudinal evaluation
Q34335875Rolling circle replication of hepatitis delta virus RNA is carried out by two different cellular RNA polymerases
Q43655020Selective strand annealing and selective strand exchange promoted by the N-terminal domain of hepatitis delta antigen
Q33845329The conserved serine 177 in the delta antigen of hepatitis delta virus is one putative phosphorylation site and is required for efficient viral RNA replication
Q36898876Transcription of subgenomic mRNA of hepatitis delta virus requires a modified hepatitis delta antigen that is distinct from antigenomic RNA synthesis
Q45382875Vaccine efficacy and immune response to swine influenza virus challenge in pigs infected with porcine reproductive and respiratory syndrome virus at the time of SIV vaccination

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