| scholarly article | Q13442814 |
| P2093 | author name string | Bryan L Roth | |
| Werner Sieghart | |||
| James M Cook | |||
| Shengming Huang | |||
| Samarpan Majumder | |||
| Terry Clayton | |||
| Joachim Ramerstorfer | |||
| Miroslav M Savić | |||
| Roman Furtmüller | |||
| Rahul V Edwankar | |||
| Marija M Milinković | |||
| Srdan Joksimović | |||
| P2860 | cites work | Molecular and neuronal substrate for the selective attenuation of anxiety. | Q51376038 |
| Benzodiazepine actions mediated by specific gamma-aminobutyric acid(A) receptor subtypes. | Q51434685 | ||
| Diazepam impairs acquisition but not performance in the Morris water maze. | Q51714959 | ||
| Laminar compartmentalization of GABAA-receptor subtypes in the spinal cord: an immunohistochemical study | Q71038900 | ||
| Benzodiazepine site inverse agonists and locomotor activity in rats: bimodal and biphasic influence | Q83843803 | ||
| Cloning of cDNA sequences encoding human alpha 2 and alpha 3 gamma-aminobutyric acidA receptor subunits and characterization of the benzodiazepine pharmacology of recombinant alpha 1-, alpha 2-, alpha 3-, and alpha 5-containing human [...] | Q24316082 | ||
| PWZ-029, a compound with moderate inverse agonist functional selectivity at GABA(A) receptors containing alpha5 subunits, improves passive, but not active, avoidance learning in rats | Q24644631 | ||
| Morris water maze: procedures for assessing spatial and related forms of learning and memory | Q28296351 | ||
| A single histidine in GABAA receptors is essential for benzodiazepine agonist binding | Q28572645 | ||
| Removing obstacles in neuroscience drug discovery: the future path for animal models | Q28755229 | ||
| Selective anxiolysis produced by ocinaplon, a GABA(A) receptor modulator. | Q28972575 | ||
| Pharmacological Properties of DOV 315,090, an ocinaplon metabolite | Q33343725 | ||
| Positioning of the alpha-subunit isoforms confers a functional signature to gamma-aminobutyric acid type A receptors. | Q34337736 | ||
| Evidence-based guidelines for the pharmacological treatment of anxiety disorders: recommendations from the British Association for Psychopharmacology | Q34465555 | ||
| GABA-A receptors: a viable target for novel anxiolytics? | Q34477287 | ||
| GABA-based therapeutic approaches: GABAA receptor subtype functions | Q34479365 | ||
| The anxioselective agent 7-(2-chloropyridin-4-yl)pyrazolo-[1,5-a]-pyrimidin-3-yl](pyridin-2-yl)methanone (DOV 51892) is more efficacious than diazepam at enhancing GABA-gated currents at alpha1 subunit-containing GABAA receptors | Q34565964 | ||
| Pharmacodynamic and pharmacokinetic effects of TPA023, a GABA(A) alpha(2,3) subtype-selective agonist, compared to lorazepam and placebo in healthy volunteers. | Q34580269 | ||
| Are GABAA receptors containing alpha5 subunits contributing to the sedative properties of benzodiazepine site agonists? | Q34613452 | ||
| NS11394 [3'-[5-(1-hydroxy-1-methyl-ethyl)-benzoimidazol-1-yl]-biphenyl-2-carbonitrile], a unique subtype-selective GABAA receptor positive allosteric modulator: in vitro actions, pharmacokinetic properties and in vivo anxiolytic efficacy | Q34827155 | ||
| World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders - first revision | Q34865036 | ||
| Antiseizure activity of novel gamma-aminobutyric acid (A) receptor subtype-selective benzodiazepine analogues in mice and rat models | Q37164117 | ||
| Target site occupancy: emerging generalizations from clinical and preclinical studies | Q37420913 | ||
| Identification of receptor domains that modify ligand binding to 5-hydroxytryptamine2 and 5-hydroxytryptamine1c serotonin receptors | Q38325476 | ||
| Endogenous [3H]flunitrazepam binding in human embryonic kidney cell line 293. | Q41359876 | ||
| The differential role of alpha1- and alpha5-containing GABA(A) receptors in mediating diazepam effects on spontaneous locomotor activity and water-maze learning and memory in rats | Q41812558 | ||
| GABA(A) receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. | Q42497057 | ||
| Comparison of the effects of zaleplon, zolpidem, and triazolam at various GABA(A) receptor subtypes | Q44136555 | ||
| GABA(A) receptor alpha-1 subunit deletion alters receptor subtype assembly, pharmacological and behavioral responses to benzodiazepines and zolpidem. | Q44170008 | ||
| Simple and sensitive liquid chromatography/tandem mass spectrometry method for the determination of diazepam and its major metabolites in rat cerebrospinal fluid | Q44351512 | ||
| Properties of single sodium channels translated by Xenopus oocytes after injection with messenger ribonucleic acid | Q44719504 | ||
| Requirement of alpha5-GABAA receptors for the development of tolerance to the sedative action of diazepam in mice. | Q44999261 | ||
| Bidirectional effects of benzodiazepine binding site ligands in the elevated plus-maze: differential antagonism by flumazenil and beta-CCt | Q45121437 | ||
| Research in anxiety disorders: from the bench to the bedside | Q46071253 | ||
| Evidence for a significant role of alpha 3-containing GABAA receptors in mediating the anxiolytic effects of benzodiazepines. | Q46807874 | ||
| Contribution of specific binding to the central benzodiazepine site to the brain concentrations of two novel benzodiazepine site ligands. | Q48135683 | ||
| Molecular basis for the GABAA receptor-mediated tonic inhibition in rat somatosensory cortex | Q48414314 | ||
| Testing the NMDA, long-term potentiation, and cholinergic hypotheses of spatial learning | Q48474421 | ||
| Factor analysis of spatiotemporal and ethological measures in the murine elevated plus-maze test of anxiety | Q48794263 | ||
| The effect of subunit composition of rat brain GABAA receptors on channel function | Q48875490 | ||
| Ethopharmacological analysis of rat behavior on the elevated plus-maze. | Q51131827 | ||
| P433 | issue | 2 | |
| P304 | page(s) | 376-386 | |
| P577 | publication date | 2010-01-13 | |
| P1433 | published in | Progress in Neuro-Psychopharmacology & Biological Psychiatry | Q15616665 |
| P1476 | title | Novel positive allosteric modulators of GABAA receptors: do subtle differences in activity at alpha1 plus alpha5 versus alpha2 plus alpha3 subunits account for dissimilarities in behavioral effects in rats? | |
| P478 | volume | 34 |
| Q26774869 | A Review of the Updated Pharmacophore for the Alpha 5 GABA(A) Benzodiazepine Receptor Model |
| Q35158189 | A novel α5GABA(A)R-positive allosteric modulator reverses hyperactivation of the dopamine system in the MAM model of schizophrenia |
| Q30429949 | Allosteric modulation of GABA(A) receptor subtypes:effects on visual recognition and visuospatial working memory in rhesus monkeys [corrected]. |
| Q30405706 | Behavioral effects of the benzodiazepine-positive allosteric modulator SH-053-2'F-S-CH₃ in an immune-mediated neurodevelopmental disruption model |
| Q36252609 | Benzodiazepine-induced spatial learning deficits in rats are regulated by the degree of modulation of α1 GABA(A) receptors |
| Q92861516 | Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia |
| Q52685000 | Design and Synthesis of Novel Deuterated Ligands Functionally Selective for the γ-Aminobutyric Acid Type A Receptor (GABAAR) α6 Subtype with Improved Metabolic Stability and Enhanced Bioavailability. |
| Q88692610 | Different Benzodiazepines Bind with Distinct Binding Modes to GABAA Receptors |
| Q37881426 | Dopamine system dysregulation by the hippocampus: implications for the pathophysiology and treatment of schizophrenia |
| Q37718469 | Enhancing the function of alpha5-subunit-containing GABAA receptors promotes action potential firing of neocortical neurons during up-states |
| Q34540561 | Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit |
| Q38820230 | Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors |
| Q37180253 | GABAA receptor modulation by piperine and a non-TRPV1 activating derivative |
| Q35175354 | Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia |
| Q35675641 | Lifelong CRF overproduction is associated with altered gene expression and sensitivity of discrete GABA(A) and mGlu receptor subtypes. |
| Q38219577 | Presynaptic dopaminergic function: implications for understanding treatment response in psychosis |
| Q40165591 | Role of gamma-aminobutyric acid type A (GABAA) receptor subtypes in acute benzodiazepine physical dependence-like effects: evidence from squirrel monkeys responding under a schedule of food presentation. |
| Q36487793 | Search for α3β₂/₃γ2 subtype selective ligands that are stable on human liver microsomes |
| Q37428156 | Sex-Dependent Anti-Stress Effect of an α5 Subunit Containing GABAA Receptor Positive Allosteric Modulator. |
| Q37718608 | Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: the approximated activation of receptor subtypes may explain behavioral effects |
| Q98288525 | Synthesis of chiral GABAA receptor subtype selective ligands as potential agents to treat schizophrenia as well as depression |
| Q48107345 | Tolerance liability of diazepam is dependent on the dose used for protracted treatment |
| Q37856292 | Use of multicomponent reactions in developing small-molecule tools to study GABAA receptor mechanism and function |
| Q61449922 | Zolpidem Activation of Alpha 1-Containing GABA Receptors Selectively Inhibits High Frequency Action Potential Firing of Cortical Neurons |
| Q39364167 | α7-nAChR agonist enhances neural plasticity in the hippocampus via a GABAergic circuit |
| Q42044694 | βCCT, an antagonist selective for α(1)GABA(A) receptors, reverses diazepam withdrawal-induced anxiety in rats |
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