| scholarly article | Q13442814 |
| review article | Q7318358 |
| P6179 | Dimensions Publication ID | 1043943583 |
| P356 | DOI | 10.1038/SJ.ONC.1203282 |
| P698 | PubMed publication ID | 10630637 |
| P5875 | ResearchGate publication ID | 12682987 |
| P2093 | author name string | C Wicking | |
| I Smyth | |||
| A Bale | |||
| P2860 | cites work | Characterization of two patched receptors for the vertebrate hedgehog protein family | Q22007983 |
| Sonic Hedgehog-induced activation of the Gli1 promoter is mediated by GLI3 | Q22009022 | ||
| Mammalian suppressor-of-fused modulates nuclear-cytoplasmic shuttling of Gli-1 | Q22010791 | ||
| Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis | Q24315133 | ||
| A mammalian patched homolog is expressed in target tissues of sonic hedgehog and maps to a region associated with developmental abnormalities | Q24315810 | ||
| Twenty proteins containing a C-terminal SOCS box form five structural classes | Q24317684 | ||
| Activating Smoothened mutations in sporadic basal-cell carcinoma | Q24318403 | ||
| The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog | Q24318676 | ||
| Mutation in GLI3 in postaxial polydactyly type A | Q24323153 | ||
| Mutations of the human homolog of Drosophila patched in the nevoid basal cell carcinoma syndrome | Q24336457 | ||
| Hedgehog signaling regulates transcription through cubitus interruptus, a sequence-specific DNA binding protein | Q24564920 | ||
| Regulation of patched by sonic hedgehog in the developing neural tube | Q24594414 | ||
| Mutations in the human Sonic Hedgehog gene cause holoprosencephaly | Q28116314 | ||
| Lessons from hereditary colorectal cancer | Q28131788 | ||
| Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein | Q28137935 | ||
| Developmental defects in Gorlin syndrome related to a putative tumor suppressor gene on chromosome 9 | Q28181962 | ||
| Compartment boundaries and the control of Drosophila limb pattern by hedgehog protein | Q28251499 | ||
| Activation of the transcription factor Gli1 and the Sonic hedgehog signalling pathway in skin tumours | Q28253060 | ||
| Identification of mutations in the human PATCHED gene in sporadic basal cell carcinomas and in patients with the basal cell nevus syndrome | Q28273158 | ||
| Mutations affecting segment number and polarity in Drosophila | Q28273492 | ||
| Human homolog of patched, a candidate gene for the basal cell nevus syndrome | Q28281033 | ||
| Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein | Q28281538 | ||
| PTCH gene mutations in invasive transitional cell carcinoma of the bladder | Q28284808 | ||
| The role of the human homologue of Drosophila patched in sporadic basal cell carcinomas | Q28288407 | ||
| Cholesterol modification of hedgehog signaling proteins in animal development | Q28291005 | ||
| Sonic hedgehog signaling is essential for hair development | Q28586200 | ||
| Altered neural cell fates and medulloblastoma in mouse patched mutants | Q28588056 | ||
| Sonic hedgehog is essential to foregut development | Q28591429 | ||
| Autoproteolysis in hedgehog protein biogenesis | Q28609804 | ||
| Suppressor of fused links fused and Cubitus interruptus on the hedgehog signalling pathway | Q28646646 | ||
| Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog | Q29615369 | ||
| Sonic hedgehog mediates the polarizing activity of the ZPA | Q29616565 | ||
| Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity | Q29616632 | ||
| HedgehogandBmpGenes Are Coexpressed at Many Diverse Sites of Cell–Cell Interaction in the Mouse Embryo | Q29618704 | ||
| SWiP-1: novel SOCS box containing WD-protein regulated by signalling centres and by Shh during development | Q33863869 | ||
| Floor plate and motor neuron induction by different concentrations of the amino-terminal cleavage product of sonic hedgehog autoproteolysis | Q34309695 | ||
| Sertoli cell signaling by Desert hedgehog regulates the male germline | Q34396888 | ||
| Biochemical evidence that patched is the Hedgehog receptor | Q34406394 | ||
| Isolation and characterization of human patched 2 (PTCH2), a putative tumour suppressor gene inbasal cell carcinoma and medulloblastoma on chromosome 1p32. | Q34490781 | ||
| Mutation hotspots due to sunlight in the p53 gene of nonmelanoma skin cancers. | Q36287125 | ||
| High levels of patched gene mutations in basal-cell carcinomas from patients with xeroderma pigmentosum | Q36338127 | ||
| The Wnt-1 (int-1) oncogene promoter and its mechanism of activation by insertion of proviral DNA of the mouse mammary tumor virus | Q36720153 | ||
| Nevoid basal cell carcinoma syndrome: review of 118 affected individuals | Q40678901 | ||
| Nuclear trafficking of Cubitus interruptus in the transcriptional regulation of Hedgehog target gene expression | Q40933908 | ||
| Somatic mutations in the human homologue of Drosophila patched in primitive neuroectodermal tumours | Q41099186 | ||
| Sonic hedgehog signaling by the patched-smoothened receptor complex | Q41607067 | ||
| Overexpression of ptc1 inhibits induction of Shh target genes and prevents normal patterning in the neural tube | Q41677627 | ||
| Cutaneous manifestations of chronic arsenicism: review of seventeen cases | Q41714328 | ||
| Basal cell carcinomas in mice overexpressing sonic hedgehog | Q42437252 | ||
| Skin cancer in chronic arsenicism | Q42440374 | ||
| Induction of basal cell carcinoma features in transgenic human skin expressing Sonic Hedgehog | Q42440751 | ||
| No evidence for the H133Y mutation in SONIC HEDGEHOG in a collection of common tumour types | Q42452827 | ||
| Mutations in the human homologue of the Drosophila patched gene in esophageal squamous cell carcinoma | Q42452938 | ||
| Keratin expression in basal cell carcinomas | Q42454007 | ||
| Rhabdomyosarcomas and radiation hypersensitivity in a mouse model of Gorlin syndrome | Q42455110 | ||
| Transducing Hedgehog: the story so far | Q42457520 | ||
| A frequent activated smoothened mutation in sporadic basal cell carcinomas | Q42467910 | ||
| Basal cell carcinoma: seven years' experience at the Institute of Dermatology in Bangkok | Q42493162 | ||
| Is human patched the gatekeeper of common skin cancers? | Q42522432 | ||
| smoothened encodes a receptor-like serpentine protein required for hedgehog signalling | Q42633905 | ||
| Cloning and characterization of the segment polarity gene cubitus interruptus Dominant of Drosophila | Q44212283 | ||
| Proteolysis That Is Inhibited by Hedgehog Targets Cubitus interruptus Protein to the Nucleus and Converts It to a Repressor | Q44894172 | ||
| Costal2, a novel kinesin-related protein in the Hedgehog signaling pathway | Q46906896 | ||
| The Drosophila smoothened gene encodes a seven-pass membrane protein, a putative receptor for the hedgehog signal | Q47070614 | ||
| Hedgehog stimulates maturation of Cubitus interruptus into a labile transcriptional activator | Q47070726 | ||
| A putative serine/threonine protein kinase encoded by the segment-polarity fused gene of Drosophila | Q47070991 | ||
| Secretion and localized transcription suggest a role in positional signaling for products of the segmentation gene hedgehog | Q47072178 | ||
| The product of hedgehog autoproteolytic cleavage active in local and long-range signalling | Q47072400 | ||
| Teratogen-mediated inhibition of target tissue response to Shh signaling | Q48004971 | ||
| Murine Model of Niemann-Pick C Disease: Mutation in a Cholesterol Homeostasis Gene | Q48047362 | ||
| Hedgehog and patched gene expression in adult ocular tissues | Q48048346 | ||
| The GLI gene is a member of the Kruppel family of zinc finger proteins | Q48327357 | ||
| Trends in survival from colonic cancer: the impact of subspecialization. | Q50910426 | ||
| Overlapping and non-overlapping Ptch2 expression with Shh during mouse embryogenesis. | Q52181378 | ||
| Control of compartmental affinity boundaries by hedgehog. | Q52559480 | ||
| GLI3 zinc-finger gene interrupted by translocations in Greig syndrome families | Q55670532 | ||
| GLI3 frameshift mutations cause autosomal dominant Pallister-Hall syndrome | Q55670535 | ||
| Nevoid basal cell carcinoma syndrome | Q72146597 | ||
| P433 | issue | 55 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 7844-7851 | |
| P577 | publication date | 1999-12-01 | |
| P1433 | published in | Oncogene | Q1568657 |
| P1476 | title | The hedgehog signalling pathway in tumorigenesis and development | |
| P478 | volume | 18 |
| Q34098937 | Aberrant Hedgehog ligands induce progressive pancreatic fibrosis by paracrine activation of myofibroblasts and ductular cells in transgenic zebrafish |
| Q42442038 | Alteration of the PATCHED locus in superficial bladder cancer |
| Q41790543 | An old friend with new skills: Imiquimod as novel inhibitor of Hedgehog signaling in basal cell carcinoma |
| Q37763105 | Basal cell carcinoma and the carcinogenic role of aberrant Hedgehog signaling |
| Q38920722 | Biodegradable polymeric micelles encapsulated JK184 suppress tumor growth through inhibiting Hedgehog signaling pathway |
| Q48224594 | Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma |
| Q37886155 | Classification of cell signalling in tissue development |
| Q28551761 | Clobetasol and Halcinonide Act as Smoothened Agonists to Promote Myelin Gene Expression and RxRγ Receptor Activation |
| Q37262785 | Co-activation of hedgehog and AKT pathways promote tumorigenesis in zebrafish |
| Q55456646 | Cross-Talk between Wnt and Hh Signaling Pathways in the Pathology of Basal Cell Carcinoma. |
| Q49929036 | Cytokeratin Profile of Basal Cell Carcinomas According to the Degree of Sun Exposure and to the Anatomical Localization. |
| Q38190332 | Deregulation of cell signaling in cancer |
| Q44463418 | Differences in the levels of Sonic hedgehog protein during early foregut development caused by exposure to Adriamycin give clues to the role of the Shh gene in oesophageal atresia |
| Q81422102 | Differential expression of Sonic hedgehog and Gli1 in hematological malignancies |
| Q26748692 | Differential role of Hedgehog signaling in human pancreatic (patho-) physiology: An up to date review |
| Q95936696 | Dual functions of Rack1 in regulating Hedgehog pathway |
| Q33584715 | Enhanced systemic immune reactivity to a Basal cell carcinoma associated antigen following photodynamic therapy |
| Q37599675 | Enhancement of anti-tumor immunity by photodynamic therapy |
| Q42509247 | Expression of the Sonic Hedgehog receptor "PATCHED" in basal cell carcinomas and odontogenic keratocysts |
| Q53396041 | Expression profiling of cancer-related genes in human keratinocytes following non-lethal ultraviolet B irradiation. |
| Q37456169 | FGFR2 abnormalities underlie a spectrum of bone, skin, and cancer pathologies |
| Q55473376 | GLI3 is not mutated commonly in sporadic medulloblastomas. |
| Q37725726 | Gastric carcinogenesis and the cancer stem cell hypothesis |
| Q38953562 | Genetic landscape of meningioma |
| Q52129573 | Genomic organization and embryonic expression of Suppressor of Fused, a candidate gene for the split-hand/split-foot malformation type 3. |
| Q42494781 | Germline mutations of the PTCH gene in families with odontogenic keratocysts and nevoid basal cell carcinoma syndrome |
| Q36674618 | Glioma-associated Oncogene 2 Is Essential for Trophoblastic Fusion by Forming a Transcriptional Complex with Glial Cell Missing-a |
| Q34132813 | Growth regulation by oncogenes--new insights from model organisms |
| Q26798191 | Hedgehog Signaling in the Maintenance of Cancer Stem Cells |
| Q92225035 | Hedgehog Signaling: An Achilles' Heel in Cancer |
| Q42502078 | Hedgehog acts as a somatic stem cell factor in the Drosophila ovary |
| Q29614405 | Hedgehog is an early and late mediator of pancreatic cancer tumorigenesis |
| Q24806020 | Hedgehog signal transduction proteins: contacts of the Fused kinase and Ci transcription factor with the kinesin-related protein Costal2. |
| Q37350250 | Hedgehog signaling in development and cancer. |
| Q52643337 | Immunohistochemical evaluation of Sonic Hedgehog signaling pathway proteins (Shh, Ptch1, Ptch2, Smo, Gli1, Gli2, and Gli3) in sporadic and syndromic odontogenic keratocysts. |
| Q28586660 | Immunolocalization of sonic hedgehog (Shh) in developing mouse lung |
| Q30993804 | In silico mining of EST databases for novel pre-implantation embryo-specific zinc finger protein genes |
| Q54550236 | Inhibition of hedgehog signaling induces monocytic differentiation of HL-60 cells. |
| Q37980076 | Intraosseous carcinoma of the jaws: a clinicopathologic review. Part III: Primary intraosseous squamous cell carcinoma |
| Q36158929 | Molecular aetiology and pathogenesis of basal cell carcinoma |
| Q34577342 | Molecular and genetic aspects of odontogenic lesions. |
| Q92817234 | Molecular characteristics of meningiomas |
| Q35790118 | Multiple gene expression analyses in paraffin-embedded tissues by TaqMan low-density array: Application to hedgehog and Wnt pathway analysis in ovarian endometrioid adenocarcinoma |
| Q24524157 | Notch signalling is linked to epidermal cell differentiation level in basal cell carcinoma, psoriasis and wound healing |
| Q38360694 | Novel genes regulated by Sonic Hedgehog in pluripotent mesenchymal cells |
| Q36752431 | Ornithine decarboxylase is a target for chemoprevention of basal and squamous cell carcinomas in Ptch1+/- mice |
| Q28585174 | Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis |
| Q34578601 | Paediatric embryonic brain tumours. biological and clinical relevance of molecular genetic abnormalities |
| Q52102705 | Patched 1 conditional null allele in mice. |
| Q34276828 | Rab23, a negative regulator of hedgehog signaling, localizes to the plasma membrane and the endocytic pathway |
| Q36524716 | Repurposing antipsychotics as glioblastoma therapeutics: Potentials and challenges |
| Q39030031 | Role of CRD-BP in the growth of human basal cell carcinoma cells |
| Q42290547 | Role of Hedgehog-Gli1 signaling in the enhanced proliferation and differentiation of MG63 cells enabled by hierarchical micro-/nanotextured topography |
| Q53404327 | Senescence bypass screen identifies TBX2, which represses Cdkn2a (p19(ARF)) and is amplified in a subset of human breast cancers. |
| Q40723935 | Several PATCHED1 missense mutations display activity in patched1-deficient fibroblasts |
| Q39089523 | Significance and prognostic value of Gli-1 and Snail/E-cadherin expression in progressive gastric cancer |
| Q37204746 | Significance of the hedgehog pathway-associated proteins Gli-1 and Gli-2 and the epithelial-mesenchymal transition-associated proteins Twist and E-cadherin in hepatocellular carcinoma |
| Q33605203 | Sonic hedgehog and tiggy-winkle hedgehog cooperatively induce zebrafish branchiomotor neurons |
| Q39846766 | Sonic hedgehog: its expression in a healing cornea and its role in neovascularization |
| Q35596587 | Stem cell in gastrointestinal structure and neoplastic development |
| Q93116110 | TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling |
| Q21129297 | The CK1 Family: Contribution to Cellular Stress Response and Its Role in Carcinogenesis |
| Q33947379 | The VACTERL association: lessons from the Sonic hedgehog pathway |
| Q38031211 | The utility of hedgehog signaling pathway inhibition for cancer |
| Q24315847 | Tumor suppressor protein VHL inhibits Hedgehog-Gli activation through suppression of Gli1 nuclear localization |
| Q39779371 | Wnt signaling stimulates transcriptional outcome of the Hedgehog pathway by stabilizing GLI1 mRNA. |
| Q73787133 | Xmeis1, a protooncogene involved in specifying neural crest cell fate in Xenopus embryos |
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