Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring

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Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring is …
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scholarly articleQ13442814

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P356DOI10.1042/CS20090640
P932PMC publication ID2860697
P698PubMed publication ID20443782
P5875ResearchGate publication ID44574421

P50authorDilys FreemanQ91941265
Naveed SattarQ37378984
Scott M. NelsonQ37381390
P2093author name stringPatrick M Catalano
Eleanor Jarvie
Sylvie Hauguel-de-Mouzon
P2860cites workVisceral and subcutaneous adipose tissue volumes are cross-sectionally related to markers of inflammation and oxidative stress: the Framingham Heart StudyQ28219755
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Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placentaQ34824188
Oxidative stress: changes in pregnancy and with gestational diabetes mellitusQ36201838
The short- and long-term implications of maternal obesity on the mother and her offspringQ36530368
Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?Q36671755
Longitudinal variance of fat mass deposition during pregnancy evaluated by ultrasonography: the ratio of visceral fat to subcutaneous fat in the abdomenQ81448976
Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress.Q51480259
Effect of fat distribution on endothelial-dependent and endothelial-independent vasodilatation in healthy humans.Q51499293
Obesity and pregnancy--the propagation of a viscous cycle?Q53920862
Longitudinal changes in body composition and energy balance in lean women with normal and abnormal glucose tolerance during pregnancy.Q54128243
Lipoprotein metabolism and vascular complications in pregnancyQ57606231
Flow‐mediated vasodilatation: variation and interrelationships with plasma lipids and lipoproteinsQ57735061
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An excess concentration of oxysterols in the plasma is cytotoxic to cultured endothelial cellsQ73515122
Longitudinal changes in glucose metabolism during pregnancy in obese women with normal glucose tolerance and gestational diabetes mellitusQ77326032
Altered hemostatic balance and endothelial activation in pregnant women with familial hypercholesterolemiaQ80128085
Differential regulation of genes for fetoplacental lipid pathways in pregnancy with gestational and type 1 diabetes mellitusQ36733274
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Role of body fat distribution and the metabolic complications of obesityQ36979749
The influence of sex and obesity phenotype on meal fatty acid metabolism before and after weight lossQ37008407
Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primatesQ37073698
Oxysterols: Sources, cellular storage and metabolism, and new insights into their roles in cholesterol homeostasisQ37402902
Cytotoxic effects of oxysterols associated with human diseases: Induction of cell death (apoptosis and/or oncosis), oxidative and inflammatory activities, and phospholipidosis.Q37402916
Inflammation and impaired adipogenesis in hypertrophic obesity in man.Q37557999
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Effects of maternal obesity on fetal growth and body composition: implications for programming and future healthQ37620719
Fatty liver and lipotoxicityQ37621647
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Changes in fat, fat-free mass and body water in human normal pregnancyQ39707548
Liver X receptors mediate inhibition of hCG secretion in a human placental trophoblast cell lineQ40361946
Abnormal carbohydrate metabolism during pregnancy : association with endothelial dysfunction.Q43903156
The influence of obesity and gestational diabetes mellitus on accretion and the distribution of adipose tissue in pregnancyQ44637278
Concentration of the oxygenated derivates of cholesterol in pregnant women suffering from diabetes type IQ44787376
Longitudinal changes in energy expenditure and body composition in obese women with normal and impaired glucose toleranceQ44869324
Low subcutaneous thigh fat is a risk factor for unfavourable glucose and lipid levels, independently of high abdominal fat. The Health ABC StudyQ45231092
Association between obesity during pregnancy and increased use of health careQ45779144
LXR-activating oxysterols induce the expression of inflammatory markers in endothelial cells through LXR-independent mechanisms.Q46019644
Involvement of NADPH oxidase in oxidized LDL-induced upregulation of heat shock factor-1 and plasminogen activator inhibitor-1 in vascular endothelial cells.Q46032945
Evidence for impaired physiological decrease in the uteroplacental vascular resistance in pregnant women with familial hypercholesterolemiaQ46274780
Oxysterol as a marker of atherogenic dyslipidemia in adolescenceQ46421690
Insulin and fatty acids regulate the expression of the fat droplet-associated protein adipophilin in primary human trophoblastsQ46783776
Determination of serum 7-ketocholesterol concentrations and their relationships with coronary multiple risks in diabetes mellitusQ46799516
Changes in plasma lipids and increased low-density lipoprotein susceptibility to oxidation in pregnancies complicated by gestational diabetes: consequences of obesityQ46940325
Lipids from oxidized low-density lipoprotein modulate human trophoblast invasion: involvement of nuclear liver X receptorsQ47225004
A longitudinal study of maternal anthropometric changes in normal weight, overweight and obese women during pregnancy and postpartumQ47230898
P275copyright licenseCreative Commons Attribution-NonCommercial 2.5 GenericQ19113746
P6216copyright statuscopyrightedQ50423863
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectobesityQ12174
pregnancy outcomeQ66057507
P304page(s)123-129
P577publication date2010-04-28
P1433published inClinical ScienceQ372419
P1476titleLipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring
P478volume119

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