| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2011PLoSO...616622A |
| P356 | DOI | 10.1371/JOURNAL.PONE.0016622 |
| P932 | PMC publication ID | 3034725 |
| P698 | PubMed publication ID | 21326877 |
| P5875 | ResearchGate publication ID | 49841501 |
| P50 | author | Anand Srivastava | Q55175663 |
| Benoit Gamain | Q55175836 | ||
| Sebastien Dechavanne | Q61099536 | ||
| Mirja Hommel | Q61820707 | ||
| P2093 | author name string | Joseph D Smith | |
| James G Beeson | |||
| Marion Avril | |||
| Marianne J Hathaway | |||
| P2860 | cites work | Antigenic variation in malaria: in situ switching, relaxed and mutually exclusive transcription of var genes during intra-erythrocytic development in Plasmodium falciparum | Q24533320 |
| Full-length extracellular region of the var2CSA variant of PfEMP1 is required for specific, high-affinity binding to CSA | Q24620671 | ||
| The Structure of a Chondroitin Sulfate-binding Domain Important in Placental Malaria | Q27650818 | ||
| Structure of the DBL3x domain of pregnancy-associated malaria protein VAR2CSA complexed with chondroitin sulfate A | Q27653526 | ||
| Structural Comparison of Two CSPG-Binding DBL Domains from the VAR2CSA Protein Important in Malaria during Pregnancy | Q27657099 | ||
| Selective upregulation of a single distinctly structured var gene in chondroitin sulphate A-adhering Plasmodium falciparum involved in pregnancy-associated malaria | Q27976511 | ||
| The large diverse gene family var encodes proteins involved in cytoadherence and antigenic variation of plasmodium falciparum-infected erythrocytes | Q29393314 | ||
| Cloning the P. falciparum gene encoding PfEMP1, a malarial variant antigen and adherence receptor on the surface of parasitized human erythrocytes | Q29618254 | ||
| Switches in expression of Plasmodium falciparum var genes correlate with changes in antigenic and cytoadherent phenotypes of infected erythrocytes | Q29618991 | ||
| IgM, Fc mu Rs, and malarial immune evasion | Q30432532 | ||
| Epitope mapping and topographic analysis of VAR2CSA DBL3X involved in P. falciparum placental sequestration | Q33263953 | ||
| HIV impairs opsonic phagocytic clearance of pregnancy-associated malaria parasites | Q33286064 | ||
| Disruption of var2csa gene impairs placental malaria associated adhesion phenotype | Q33299476 | ||
| Structural insight into epitopes in the pregnancy-associated malaria protein VAR2CSA | Q33320197 | ||
| Several domains from VAR2CSA can induce Plasmodium falciparum adhesion-blocking antibodies | Q33634689 | ||
| Cross-reactive surface epitopes on chondroitin sulfate A-adherent Plasmodium falciparum-infected erythrocytes are associated with transcription of var2csa | Q33769127 | ||
| Evaluation of the antigenic diversity of placenta-binding Plasmodium falciparum variants and the antibody repertoire among pregnant women | Q33826049 | ||
| Immunization with VAR2CSA-DBL5 recombinant protein elicits broadly cross-reactive antibodies to placental Plasmodium falciparum-infected erythrocytes | Q33826076 | ||
| Subtelomeric chromosome deletions in field isolates of Plasmodium falciparum and their relationship to loss of cytoadherence in vitro | Q33848276 | ||
| Identification of Plasmodium falciparum var1CSA and var2CSA domains that bind IgM natural antibodies | Q33849078 | ||
| Full-length recombinant Plasmodium falciparum VAR2CSA binds specifically to CSPG and induces potent parasite adhesion-blocking antibodies | Q34095324 | ||
| A single member of the Plasmodium falciparum var multigene family determines cytoadhesion to the placental receptor chondroitin sulphate A. | Q34360455 | ||
| Evidence for the involvement of VAR2CSA in pregnancy-associated malaria | Q34364093 | ||
| A family affair: var genes, PfEMP1 binding, and malaria disease | Q34543611 | ||
| Baculovirus-expressed constructs induce immunoglobulin G that recognizes VAR2CSA on Plasmodium falciparum-infected erythrocytes | Q34721210 | ||
| Transcribed var genes associated with placental malaria in Malawian women. | Q34975870 | ||
| The sick placenta-the role of malaria. | Q35744707 | ||
| Antibodies that inhibit Plasmodium falciparum adhesion to chondroitin sulfate A are associated with increased birth weight and the gestational age of newborns | Q36374795 | ||
| Evidence for globally shared, cross-reacting polymorphic epitopes in the pregnancy-associated malaria vaccine candidate VAR2CSA. | Q36539548 | ||
| Antigenic differences and conservation among placental Plasmodium falciparum-infected erythrocytes and acquisition of variant-specific and cross-reactive antibodies | Q36789977 | ||
| Var2CSA DBL6-epsilon domain expressed in HEK293 induces limited cross-reactive and blocking antibodies to CSA binding parasites. | Q36891434 | ||
| An in vivo and in vitro model of Plasmodium falciparum rosetting and autoagglutination mediated by varO, a group A var gene encoding a frequent serotype | Q36974515 | ||
| Plasmodium falciparum isolates from infected pregnant women and children are associated with distinct adhesive and antigenic properties | Q37036123 | ||
| Antibodies to variant surface antigens of Plasmodium falciparum-infected erythrocytes and adhesion inhibitory antibodies are associated with placental malaria and have overlapping and distinct targets | Q37036128 | ||
| Induction of adhesion-inhibitory antibodies against placental Plasmodium falciparum parasites by using single domains of VAR2CSA. | Q37204480 | ||
| Optimizing expression of the pregnancy malaria vaccine candidate, VAR2CSA in Pichia pastoris | Q37271796 | ||
| Human pregnancy-associated malaria-specific B cells target polymorphic, conformational epitopes in VAR2CSA | Q37426131 | ||
| Structural basis for binding of Plasmodium falciparum erythrocyte membrane protein 1 to chondroitin sulfate and placental tissue and the influence of protein polymorphisms on binding specificity | Q38300914 | ||
| High level of var2csa transcription by Plasmodium falciparum isolated from the placenta | Q38324821 | ||
| Variable adhesion abilities and overlapping antigenic properties in placental Plasmodium falciparum isolates | Q39537054 | ||
| Plasmodium falciparum: VAR2CSA expressed during pregnancy-associated malaria is partially resistant to proteolytic cleavage by trypsin | Q40144118 | ||
| Identification of multiple chondroitin sulfate A (CSA)-binding domains in the var2CSA gene transcribed in CSA-binding parasites | Q41459429 | ||
| Chondroitin sulphate A (CSA)-binding of single recombinant Duffy-binding-like domains is not restricted to Plasmodium falciparum Erythrocyte Membrane Protein 1 expressed by CSA-binding parasites | Q43415044 | ||
| High efficacy of anti DBL4ɛ-VAR2CSA antibodies in inhibition of CSA-binding Plasmodium falciparum-infected erythrocytes from pregnant women | Q43941189 | ||
| VAR2CSA expression on the surface of placenta-derived Plasmodium falciparum-infected erythrocytes | Q44956636 | ||
| Adherence of Plasmodium falciparum to chondroitin sulfate A in the human placenta | Q45249046 | ||
| VAR2CSA domains expressed in Escherichia coli induce cross-reactive antibodies to native protein | Q46608178 | ||
| Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria | Q47232540 | ||
| Structural polymorphism and diversifying selection on the pregnancy malaria vaccine candidate VAR2CSA. | Q47765536 | ||
| Maternal antibodies block malaria | Q47838841 | ||
| Biased distribution of msp1 and msp2 allelic variants in Plasmodium falciparum populations in Thailand | Q47858805 | ||
| Plasmodium falciparum-infected erythrocytes demonstrate dual specificity for adhesion to hyaluronic acid and chondroitin sulfate A and have distinct adhesive properties | Q47973172 | ||
| VAR2CSA is the principal ligand for chondroitin sulfate A in two allogeneic isolates of Plasmodium falciparum | Q48028019 | ||
| Plasmodium falciparum: Effect of time in continuous culture on binding to human endothelial cells and amelanotic melanoma cells | Q57044377 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 2 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | e16622 | |
| P577 | publication date | 2011-02-07 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Antibodies to a full-length VAR2CSA immunogen are broadly strain-transcendent but do not cross-inhibit different placental-type parasite isolates | |
| P478 | volume | 6 |
| Q51417360 | A Specific PfEMP1 Is Expressed in P. falciparum Sporozoites and Plays a Role in Hepatocyte Infection. |
| Q36804761 | Antibodies to Escherichia coli-expressed C-terminal domains of Plasmodium falciparum variant surface antigen 2-chondroitin sulfate A (VAR2CSA) inhibit binding of CSA-adherent parasites to placental tissue |
| Q36354336 | Beninese children with cerebral malaria do not develop humoral immunity against the IT4-VAR19-DC8 PfEMP1 variant linked to EPCR and brain endothelial binding |
| Q33911270 | CRISPR/Cas9 Genome Editing Reveals That the Intron Is Not Essential for var2csa Gene Activation or Silencing in Plasmodium falciparum |
| Q39066692 | Comparison of functional assays used in the clinical development of a placental malaria vaccine |
| Q34498103 | Designing a VAR2CSA-based vaccine to prevent placental malaria |
| Q38519513 | Developing vaccines to prevent malaria in pregnant women |
| Q43171908 | Expanding the toolbox in pursuit of a strain transcendent malaria vaccine |
| Q93109754 | Functional Antibodies against Placental Malaria Parasites Are Variant Dependent and Differ by Geographic Region |
| Q47999224 | Identification of Id1-DBL2X of VAR2CSA as a key domain inducing highly inhibitory and cross-reactive antibodies |
| Q36668512 | Identification of VAR2CSA domain-specific inhibitory antibodies of the Plasmodium falciparum erythrocyte membrane protein 1 using a novel flow cytometry assay |
| Q35783076 | Identification of a Major Dimorphic Region in the Functionally Critical N-Terminal ID1 Domain of VAR2CSA. |
| Q27301377 | Immunogenicity of the Plasmodium falciparum PfEMP1-VarO Adhesin: Induction of Surface-Reactive and Rosette-Disrupting Antibodies to VarO Infected Erythrocytes |
| Q36558721 | Multilaboratory approach to preclinical evaluation of vaccine immunogens for placental malaria |
| Q37002285 | Murine Model for Preclinical Studies of Var2CSA-Mediated Pathology Associated with Malaria in Pregnancy |
| Q89595553 | PRIMVAC vaccine adjuvanted with Alhydrogel or GLA-SE to prevent placental malaria: a first-in-human, randomised, double-blind, placebo-controlled study |
| Q92632114 | Phosphorylation of the VAR2CSA extracellular region is associated with enhanced adhesive properties to the placental receptor CSA |
| Q38691920 | Pre-clinical and clinical development of the first placental malaria vaccine |
| Q64086386 | Preclinical immunogenicity and safety of the cGMP-grade placental malaria vaccine PRIMVAC |
| Q35738477 | Prospects and Pitfalls of Pregnancy-Associated Malaria Vaccination Based on the Natural Immune Response to Plasmodium falciparum VAR2CSA-Expressing Parasites |
| Q36078717 | Structural and functional insight into how the Plasmodium falciparum VAR2CSA protein mediates binding to chondroitin sulfate A in placental malaria. |
| Q34161839 | Surface antigens of Plasmodium falciparum-infected erythrocytes as immune targets and malaria vaccine candidates |
| Q39698908 | The case for PfEMP1-based vaccines to protect pregnant women against Plasmodium falciparum malaria |
| Q34921119 | VAR2CSA signatures of high Plasmodium falciparum parasitemia in the placenta |
| Q30401849 | Vaccination with Killed but Metabolically Active E. coli Over-expressing Hemagglutinin Elicits Neutralizing Antibodies to H1N1 Swine Origin Influenza A Virus |
| Q28744428 | Var2CSA minimal CSA binding region is located within the N-terminal region |
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