TARP γ-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn

scientific article

TARP γ-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1523/JNEUROSCI.0772-16.2017
P932PMC publication ID5481940
P698PubMed publication ID28559374

P50authorStuart Cull-CandyQ7626438
Mark FarrantQ56993626
Steve J SullivanQ59553126
P2860cites workImproved structure, function and compatibility for CellProfiler: modular high-throughput image analysis softwareQ24622701
Neuronal circuitry for pain processing in the dorsal hornQ24633123
Functional studies and distribution define a family of transmembrane AMPA receptor regulatory proteinsQ24652235
CellProfiler: image analysis software for identifying and quantifying cell phenotypesQ24676898
A role of TARPs in the expression and plasticity of calcium-permeable AMPARs: evidence from cerebellar neurons and gliaQ26999034
TARP auxiliary subunits switch AMPA receptor antagonists into partial agonistsQ27648934
Glutamate receptor ion channels: structure, regulation, and functionQ28290774
Selective regulation of long-form calcium-permeable AMPA receptors by an atypical TARP, gamma-5Q28571727
The interaction between Stargazin and PSD-95 regulates AMPA receptor surface traffickingQ28581802
CaMKII triggers the diffusional trapping of surface AMPARs through phosphorylation of stargazinQ28583959
Origins of spontaneous and noxious stimuli-evoked miniature EPSCs in substantia gelatinosaQ31997895
Susceptibility to chronic pain following nerve injury is genetically affected by CACNG2.Q34085118
Down-regulation of Stargazin inhibits the enhanced surface delivery of α-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor GluR1 subunit in rat dorsal horn and ameliorates postoperative painQ34195160
Synaptic amplifier of inflammatory pain in the spinal dorsal hornQ34538726
Light microscope study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat.Q34667685
Inflammation alters trafficking of extrasynaptic AMPA receptors in tonically firing lamina II neurons of the rat spinal dorsal hornQ34814471
Stargazin (TARP gamma-2) is required for compartment-specific AMPA receptor trafficking and synaptic plasticity in cerebellar stellate cellsQ35015206
The expanding social network of ionotropic glutamate receptors: TARPs and other transmembrane auxiliary subunitsQ35058291
Transmembrane AMPAR regulatory protein γ-2 is required for the modulation of GABA release by presynaptic AMPARsQ35164064
TARP redundancy is critical for maintaining AMPA receptor function.Q35173377
Populations of inhibitory and excitatory interneurons in lamina II of the adult rat spinal dorsal horn revealed by a combined electrophysiological and anatomical approachQ35207942
Bidirectional plasticity of calcium-permeable AMPA receptors in oligodendrocyte lineage cellsQ35477152
Two components of transmitter release at a central synapseQ36013914
Fast synaptic inhibition in spinal sensory processing and pain controlQ36661675
Moving from an averaged to specific view of spinal cord pain processing circuits.Q36849109
Excitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itchQ36979347
Persistent inflammation induces GluR2 internalization via NMDA receptor-triggered PKC activation in dorsal horn neuronsQ37148281
Nerve injury increases GluA2-lacking AMPA receptor prevalence in spinal cords: functional significance and signaling mechanismsQ37331824
Central sensitization: a generator of pain hypersensitivity by central neural plasticityQ37361185
TARP γ-7 selectively enhances synaptic expression of calcium-permeable AMPARsQ37381920
Transmembrane AMPA receptor regulatory proteins and AMPA receptor function in the cerebellumQ37382484
Morphological, biophysical and synaptic properties of glutamatergic neurons of the mouse spinal dorsal hornQ37603182
Transmitting pain and itch messages: a contemporary view of the spinal cord circuits that generate gate control.Q38210421
Cobalt accumulation in neurons expressing ionotropic excitatory amino acid receptors in young rat spinal cord: morphology and distributionQ39396341
The mouse stargazer gene encodes a neuronal Ca2+-channel gamma subunit.Q41017868
Inward rectification of both AMPA and kainate subtype glutamate receptors generated by polyamine-mediated ion channel blockQ41316722
Mechanical allodynia in rats is blocked by a Ca2+ permeable AMPA receptor antagonistQ41711894
Non-Hebbian plasticity at C-fiber synapses in rat spinal cord lamina I neuronsQ41818691
A putative relay circuit providing low-threshold mechanoreceptive input to lamina I projection neurons via vertical cells in lamina II of the rat dorsal horn.Q41883493
Channel properties reveal differential expression of TARPed and TARPless AMPARs in stargazer neurons.Q42087958
Dorsal Horn Circuits for Persistent Mechanical PainQ42141599
The AMPA receptor subunits GluR-A and GluR-B reciprocally modulate spinal synaptic plasticity and inflammatory painQ42470459
TARP gamma-8 controls hippocampal AMPA receptor number, distribution and synaptic plasticityQ42485237
Expression of AMPA receptor subunits at synapses in laminae I-III of the rodent spinal dorsal horn.Q43052698
Pain models display differential sensitivity to Ca2+-permeable non-NMDA glutamate receptor antagonistsQ43769836
Differential Roles of Phosphorylated AMPA Receptor GluR1 Subunits at Serine-831 and Serine-845 Sites in Spinal Cord Dorsal Horn in a Rat Model of Post-Operative PainQ43839674
A simple exploratory algorithm for the accurate and fast detection of spontaneous synaptic eventsQ44111610
Distribution of transmembrane AMPA receptor regulatory protein (TARP) isoforms in the rat spinal cord.Q44133225
The expression of vesicular glutamate transporters VGLUT1 and VGLUT2 in neurochemically defined axonal populations in the rat spinal cord with emphasis on the dorsal hornQ44282752
Expression of vesicular glutamate transporters, VGluT1 and VGluT2, in axon terminals of nociceptive primary afferent fibers in the superficial layers of the medullary and spinal dorsal horns of the rat.Q44286829
Selective loss of spinal GABAergic or glycinergic neurons is not necessary for development of thermal hyperalgesia in the chronic constriction injury model of neuropathic pain.Q44509534
Widespread expression of the AMPA receptor GluR2 subunit at glutamatergic synapses in the rat spinal cord and phosphorylation of GluR1 in response to noxious stimulation revealed with an antigen-unmasking method.Q44950472
Bidirectional synaptic plasticity regulated by phosphorylation of stargazin-like TARPs.Q45233498
Spinal distribution of c-Fos activated neurons expressing enkephalin in acute and chronic pain modelsQ46067129
Stargazin modulates AMPA receptor gating and trafficking by distinct domainsQ46461380
Translocation of GluR1-containing AMPA receptors to a spinal nociceptive synapse during acute noxious stimulation.Q46492778
N-ethylmaleimide-sensitive fusion protein (NSF) is involved in central sensitization in the spinal cord through GluR2 subunit composition switch after inflammationQ46504263
Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8.Q46580501
Estimated conductance of glutamate receptor channels activated during EPSCs at the cerebellar mossy fiber-granule cell synapseQ46701482
Switch to Ca2+-permeable AMPA and reduced NR2B NMDA receptor-mediated neurotransmission at dorsal horn nociceptive synapses during inflammatory pain in the rat.Q46885932
Preferential origin and layer destination of GAD65-GFP cortical interneuronsQ47308563
TARPs gamma-2 and gamma-7 are essential for AMPA receptor expression in the cerebellumQ48174384
Enhanced carbodiimide fixation for immunohistochemistry: application to the comparative distributions of N-acetylaspartylglutamate and N-acetylaspartate immunoreactivities in rat brainQ48312553
Selective scarcity of NMDA receptor channel subunits in the stratum lucidum (mossy fibre-recipient layer) of the mouse hippocampal CA3 subfieldQ48389295
Capsaicin facilitates excitatory but not inhibitory synaptic transmission in substantia gelatinosa of the rat spinal cord.Q51489330
Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8.Q52140843
Small-caliber afferent inputs produce a heterosynaptic facilitation of the synaptic responses evoked by primary afferent A-fibers in the neonatal rat spinal cord in vitro.Q52224626
Selective neuronal glycoconjugate expression in sensory and autonomic ganglia: relation of lectin reactivity to peptide and enzyme markers.Q54315234
Intracellular spermine confers rectification on rat calcium-permeable AMPA and kainate receptorsQ57985787
Ca(2+)-permeable AMPA and NMDA receptor channels in basket cells of rat hippocampal dentate gyrusQ71709014
Development of arthritis, periarthritis and periostitis in rats given adjuvantsQ73940011
The distribution of neurons expressing calcium-permeable AMPA receptors in the superficial laminae of the spinal cord dorsal hornQ74582907
New role for spinal Stargazin in alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor-mediated pain sensitization after inflammationQ79769462
Excitatory interneurons dominate sensory processing in the spinal substantia gelatinosa of ratQ79855284
Spatial diversity in gene expression for VDCCgamma subunit family in developing and adult mouse brainsQ81235280
Both Ca2+-permeable and -impermeable AMPA receptors contribute to primary synaptic drive onto rat dorsal horn neuronsQ83954341
P4510describes a project that usesImageJQ1659584
RStudioQ4798119
CellProfilerQ5058134
P433issue25
P407language of work or nameEnglishQ1860
P304page(s)6007-6020
P577publication date2017-05-30
P1433published inJournal of NeuroscienceQ1709864
P1476titleTARP γ-2 Is Required for Inflammation-Associated AMPA Receptor Plasticity within Lamina II of the Spinal Cord Dorsal Horn
P478volume37

Reverse relations

cites work (P2860)
Q95840615AMPAR/TARP stoichiometry differentially modulates channel properties
Q58115880CACNG2 polymorphisms associate with chronic pain following mastectomy
Q91703368Interferon-γ facilitates the synaptic transmission between primary afferent C-fibres and lamina I neurons in the rat spinal dorsal horn via microglia activation
Q54244939Lung-injury depresses glutamatergic synaptic transmission in the nucleus tractus solitarii via discrete age-dependent mechanisms in neonatal rats.
Q90216562Quantitative proteomics reveal the alterations in the spinal cord after myocardial ischemia‑reperfusion injury in rats
Q93383632Regulatory Architecture of the Neuronal Cacng2/Tarpγ2 Gene Promoter: Multiple Repressive Domains, a Polymorphic Regulatory Short Tandem Repeat, and Bidirectional Organization with Co-regulated lncRNAs

Search more.