Molecular Basis of Alcohol-Related Gastric and Colon Cancer

scientific article

Molecular Basis of Alcohol-Related Gastric and Colon Cancer is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.3390/IJMS18061116
P932PMC publication ID5485940
P698PubMed publication ID28538665

P2093author name stringJa Young Lee
Hye-Kyung Na
P2860cites workDecreased expression of monocyte chemoattractant protein-1 predicts poor prognosis following curative resection of colorectal cancerQ81655134
Commentary: acetaldehyde and epithelial-to-mesenchymal transition in colonQ86749067
Alcoholic liver disease and hepatitis C: a frequently underestimated combinationQ22305502
Molecular abnormality of an inactive aldehyde dehydrogenase variant commonly found in OrientalsQ24598439
Alcohol metabolismQ24621827
A meta-analysis of alcohol drinking and cancer riskQ24648591
Pathogenesis of Helicobacter pylori infectionQ24679810
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012Q27861047
Alcohol stimulates activation of Snail, epidermal growth factor receptor signaling, and biomarkers of epithelial-mesenchymal transition in colon and breast cancer cellsQ28262663
Mechanisms of alcohol-associated cancers: introduction and summary of the symposiumQ28264663
Alcohol-related cancers and aldehyde dehydrogenase-2 in Japanese alcoholicsQ28282984
Alcohol and cancerQ28295240
Ethanol modulation of intestinal epithelial tight junction barrierQ28373345
Effects of diet and ethanol on the expression and localization of cytochromes P450 2E1 and P450 2C7 in the colon of male ratsQ28569561
The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwideQ29616215
Attributable fraction of alcohol consumption on cancer using population-based nationwide cancer incidence and mortality data in the Republic of KoreaQ30830331
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2014Q33584023
Gene promoter methylation in colorectal cancer and healthy adjacent mucosa specimens: correlation with physiological and pathological characteristics, and with biomarkers of one-carbon metabolismQ34000439
Gastric alcohol dehydrogenase activity in man: influence of gender, age, alcohol consumption and smoking in a caucasian populationQ34137631
Transactivation of MCP-1/CCL2 by beta-catenin/TCF-4 in human breast cancer cellsQ34249533
Alcoholic beverages and carbonated soft drinks: consumption and gastrointestinal cancer risks.Q34376849
In vitro acetaldehyde formation by human colonic bacteriaQ34382058
Role of hepatic and intestinal p450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in miceQ34405400
Identification of the gene encoding hydroxyacid-oxoacid transhydrogenase, an enzyme that metabolizes 4-hydroxybutyrateQ34514146
Meta-analyses of ALDH2 and ADH1B with alcohol dependence in Asians.Q34544887
Ethanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway.Q34591341
Acetaldehyde in mainstream tobacco smoke: formation and occurrence in smoke and bioavailability in the smokerQ35000879
Polymorphisms in alcohol metabolism genes ADH1B and ALDH2, alcohol consumption and colorectal cancer.Q35055053
Transgenic mouse models for alcohol metabolism, toxicity, and cancerQ35069133
Retracted: ALDH2 and ADH1 Genetic Polymorphisms May Contribute to the Risk of Gastric Cancer: A Meta-AnalysisQ35122074
Effects of ALDH2 genotype, PPI treatment and L-cysteine on carcinogenic acetaldehyde in gastric juice and saliva after intragastric alcohol administrationQ35242343
Alcohol consumption and the etiology of colorectal cancer: a review of the scientific evidence from 1957 to 1991Q35530804
Alcohol Drinking, Cigarette Smoking and Risk of Colorectal Cancer in the Korean Multi-center Cancer Cohort.Q35820991
Effect of alcohol on the development of hepatocellular carcinoma in patients with hepatitis B virus-related cirrhosis: a cross-sectional case-control studyQ35832967
Alcohol, one-carbon metabolism, and colorectal cancer: recent insights from molecular studiesQ35873162
Chronic ethanol feeding promotes azoxymethane and dextran sulfate sodium-induced colonic tumorigenesis potentially by enhancing mucosal inflammationQ35948499
Ethanol enhances arsenic-induced cyclooxygenase-2 expression via both NFAT and NF-κB signalings in colorectal cancer cellsQ36103814
Role of MCP-1 in alcohol-induced aggressiveness of colorectal cancer cellsQ36319698
Promotion by ethanol of gastric carcinogenesis induced by N-methyl-N'-nitro-N-nitrosoguanidine in Wistar ratsQ36467762
Impact of alcohol drinking on gastric cancer development according to Helicobacter pylori infection statusQ36750651
Ethanol enhances tumor angiogenesis in vitro induced by low-dose arsenic in colon cancer cells through hypoxia-inducible factor 1 alpha pathwayQ36752710
Molecular mechanisms of alcohol-mediated carcinogenesisQ36889966
Chronic inflammation and oxidative stress in human carcinogenesisQ36950970
Ethanol-induced mast cell-mediated inflammation leads to increased susceptibility of intestinal tumorigenesis in the APC Δ468 min mouse model of colon cancerQ36959480
Oxidative mechanisms in the pathogenesis of alcoholic liver disease.Q37018272
Genes encoding enzymes involved in ethanol metabolismQ37130460
Alcohol metabolism and epigenetics changesQ37386432
Alcohol Consumption and Gastric Cancer Risk: A Meta-Analysis.Q37600034
Cancer prevention in the Asia Pacific region.Q37816378
Acetaldehyde and gastric cancerQ37852813
Alcohol and aldehyde dehydrogenaseQ37943304
Prediagnosis lifestyle exposures and survival of patients with gastric cancer: systematic review and meta-analysisQ38001887
The role of cytochrome P450 2E1 in ethanol-mediated carcinogenesisQ38080780
Association of risk of gastric cancer and consumption of tobacco, alcohol and tea in the Chinese population.Q38265459
The role of reactive oxygen species (ROS) and cytochrome P-450 2E1 in the generation of carcinogenic etheno-DNA adductsQ38280869
Chronic Effects of Ethanol and/or Darunavir/Ritonavir on U937 Monocytic Cells: Regulation of Cytochrome P450 and Antioxidant Enzymes, Oxidative Stress, and CytotoxicityQ38806803
Mast cells positive to tryptase and tumour-associated macrophages correlate with angiogenesis in locally advanced colorectal cancer patients undergone to surgeryQ39968854
A gene-gene interaction between ALDH2 Glu487Lys and ADH2 His47Arg polymorphisms regarding the risk of colorectal cancer in JapanQ40367257
Effect of alcohol on gastrointestinal cell regeneration as a possible mechanism in alcohol-associated carcinogenesisQ40539993
Phosphatidylethanol formation and degradation in human and rat bloodQ40604843
Bacteriocolonic pathway for ethanol oxidation: characteristics and implicationsQ41114732
Characteristics of alcohol dehydrogenases of certain aerobic bacteria representing human colonic floraQ42549449
Ethanol upregulates iNOS expression in colon through activation of nuclear factor-kappa B in ratsQ43254012
Differential effects of CYP2E1 status on the metabolic activation of the colon carcinogens azoxymethane and methylazoxymethanol.Q43814390
Ethanol-derived microbial production of carcinogenic acetaldehyde in achlorhydric atrophic gastritisQ44069774
Enhancing effect of ethanol or saké on methylazoxymethanol acetate-initiated large bowel carcinogenesis in ACI/N ratsQ44139738
Ethanol promotes intestinal tumorigenesis in the MIN mouse. Multiple intestinal neoplasiaQ44217834
Inhibition of alcohol-associated colonic hyperregeneration by alpha-tocopherol in the rat.Q44288825
Effects of dietary folate and alcohol intake on promoter methylation in sporadic colorectal cancer: the Netherlands cohort study on diet and cancerQ44480732
Ethanol-induced colitis prevents oral tolerance induction in miceQ44560978
Dose-dependent effects of ethanol and E. coli on gut permeability and cytokine production.Q45989548
Increased formation of gastric N(2)-ethylidene-2'-deoxyguanosine DNA adducts in aldehyde dehydrogenase-2 knockout mice treated with ethanolQ46186918
Folate-mediated one-carbon metabolismQ46356485
Epidemiological evidence that acetaldehyde plays a significant role in the development of decreased serum folate concentration and elevated mean corpuscular volume in alcohol drinkersQ46440604
Major Anaerobic Bacteria Responsible for the Production of Carcinogenic Acetaldehyde from Ethanol in the Colon and Rectum.Q46612133
Protective effects of green tea polyphenol extracts against ethanol-induced gastric mucosal damages in rats: stress-responsive transcription factors and MAP kinases as potential targetsQ46646172
Phosphatidylethanol accumulation promotes intestinal hyperplasia by inducing ZONAB-mediated cell density increase in response to chronic ethanol exposureQ46891737
N-nitrosodimethylamine-derived O(6)-methylguanine in DNA of monkey gastrointestinal and urogenital organs and enhancement by ethanolQ49050916
Effect of chronic dietary ethanol consumption on colonic cancer in rats induced by 1,1-dimethylhydrazine.Q50471225
Liver cirrhosis and the risk of primary liver cancer.Q50858591
Increased DNA damage in ALDH2-deficient alcoholics.Q51719786
Cell proliferation and its evaluation in the colorectal mucosa: effect of ethanol.Q53430125
Tobacco, alcohol, and colorectal tumors: a multistep process.Q53463356
In vitro alcohol dehydrogenase-mediated acetaldehyde production by aerobic bacteria representing the normal colonic flora in man.Q54581617
Genetic polymorphisms of ADH1B, ADH1C and ALDH2, alcohol consumption, and the risk of gastric cancer: the Japan Public Health Center-based prospective studyQ57918048
Possible role of acetaldehyde in ethanol-related rectal cocarcinogenesis in the ratQ63363822
Attributable risk for diet, alcohol, and family history in the Melbourne colorectal cancer studyQ67479275
Alcohol dehydrogenase mediated acetaldehyde production by Helicobacter pylori--a possible mechanism behind gastric injuryQ67560334
Aldehyde dehydrogenases of the rat colon: comparison with other tissues of the alimentary tract and the liverQ71313544
Microbially produced acetaldehyde from ethanol may increase the risk of colon cancer via folate deficiencyQ73595169
Helicobacter pylori, chronic atrophic gastritis, inactive aldehyde dehydrogenase-2, macrocytosis and multiple upper aerodigestive tract cancers and the risk for gastric cancer in alcoholic Japanese menQ79763494
Interrelationship between alcohol, smoking, acetaldehyde and cancerQ80525365
P275copyright licenseCreative Commons AttributionQ6905323
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectalcoholsQ156
alcohol consumptionQ2647488
colonic neoplasmQ3542029
stomach neoplasmQ4335552
ethanolQ153
colon cancerQ18555025
P5008on focus list of Wikimedia projectScienceSourceQ55439927
P577publication date2017-05-24
P1433published inInternational Journal of Molecular SciencesQ3153277
P1476titleMolecular Basis of Alcohol-Related Gastric and Colon Cancer
P478volume18

Reverse relations

cites work (P2860)
Q100635816Alcohol consumption is associated with glaucoma severity regardless of ALDH2 polymorphism
Q47107745Alcohol, stem cells and cancer
Q65002228Alcoholism: A Multi-Systemic Cellular Insult to Organs.
Q45590471Association of insertion-deletions polymorphisms with colorectal cancer risk and clinical features.
Q92891565CYP2E1 changes the biological function of gastric cancer cells via the PI3K/Akt/mTOR signaling pathway
Q48132576Colorectal Cancer and Alcohol Consumption-Populations to Molecules
Q90429865Contributing Roles of CYP2E1 and Other Cytochrome P450 Isoforms in Alcohol-Related Tissue Injury and Carcinogenesis
Q64084702Development of colorectal cancer predicts increased risk of subsequent hepatocellular carcinoma in patients with alcoholic liver disease: case-control and cohort study
Q92188616Effects of Xingnaojing Injection on Adenosinergic Transmission and Orexin Signaling in Lateral Hypothalamus of Ethanol-Induced Coma Rats

Search more.