Identification of paramyxovirus V protein residues essential for STAT protein degradation and promotion of virus replication

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Identification of paramyxovirus V protein residues essential for STAT protein degradation and promotion of virus replication is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/JVI.79.13.8591-8601.2005
P932PMC publication ID1143765
P698PubMed publication ID15956600

P2093author name stringDominique Garcin
Daniel Kolakofsky
Machiko Nishio
Masato Tsurudome
Morihiro Ito
Yasuhiko Ito
P2860cites workParamyxoviridae use distinct virus-specific mechanisms to circumvent the interferon responseQ40831794
Normal cellular replication of Sendai virus without the trans-frame, nonstructural V proteinQ41128631
Recombinant measles viruses defective for RNA editing and V protein synthesis are viable in cultured cellsQ41133607
The paramyxovirus SV5 V protein binds two atoms of zinc and is a structural component of virionsQ41351891
NP:P and NP:V interactions of the paramyxovirus simian virus 5 examined using a novel protein:protein capture assayQ42543132
Two mRNAs that differ by two nontemplated nucleotides encode the amino coterminal proteins P and V of the paramyxovirus SV5.Q42652641
Human parainfluenza virus type 2 phosphoprotein: mapping of monoclonal antibody epitopes and location of the multimerization domainQ43540600
The carboxyl segment of the mumps virus V protein associates with Stat proteins in vitro via a tryptophan-rich motifQ43589572
Recovery of infectious human parainfluenza type 2 virus from cDNA clones and properties of the defective virus without V-specific cysteine-rich domainQ43607462
Knockout of the Sendai virus C gene eliminates the viral ability to prevent the interferon-alpha/beta-mediated responsesQ43909821
Extensive antigenic diversity among human parainfluenza type 2 virus isolates and immunological relationships among paramyxoviruses revealed by monoclonal antibodiesQ44763381
Sendai virus C protein physically associates with Stat1.Q45736579
Isolation of monoclonal antibodies directed against the V protein of human parainfluenza virus type 2 and localization of the V protein in virus-infected cellsQ45743352
Interaction between nucleocapsid protein (NP) and phosphoprotein (P) of human parainfluenza virus type 2: one of the two NP binding sites on P is essential for granule formationQ45766922
Binding of the V proteins to the nucleocapsid proteins of human parainfluenza type 2 virusQ45766982
Identification of the sequences responsible for nuclear targeting of the V protein of human parainfluenza virus type 2.Q45770887
Incomplete replication of human parainfluenza virus type 2 in mouse L929 cellsQ45846949
Paramyxoviruses SV5 and HPIV2 assemble STAT protein ubiquitin ligase complexes from cellular componentsQ48726950
The V protein of the paramyxovirus SV5 interacts with damage-specific DNA binding proteinQ77310751
The paramyxovirus, Sendai virus, V protein encodes a luxury function required for viral pathogenesisQ24532096
The p127 subunit (DDB1) of the UV-DNA damage repair binding protein is essential for the targeted degradation of STAT1 by the V protein of the paramyxovirus simian virus 5Q24538935
Stat protein transactivation domains recruit p300/CBP through widely divergent sequencesQ28143105
Sendai virus C proteins must interact directly with cellular components to interfere with interferon actionQ33604006
The paramyxovirus simian virus 5 V protein slows progression of the cell cycleQ33604667
Sendai virus and simian virus 5 block activation of interferon-responsive genes: importance for virus pathogenesisQ33644511
Sendai virus C proteins counteract the interferon-mediated induction of an antiviral stateQ33817139
Single amino acid substitution in the V protein of simian virus 5 differentiates its ability to block interferon signaling in human and murine cellsQ33838481
High resistance of human parainfluenza type 2 virus protein-expressing cells to the antiviral and anti-cell proliferative activities of alpha/beta interferons: cysteine-rich V-specific domain is required for high resistance to the interferonsQ33845465
Y2, the smallest of the Sendai virus C proteins, is fully capable of both counteracting the antiviral action of interferons and inhibiting viral RNA synthesisQ33851312
Sequence analysis of P gene of human parainfluenza type 2 virus: P and cysteine-rich proteins are translated by two mRNAs that differ by two nontemplated G residuesQ33914806
STAT2 acts as a host range determinant for species-specific paramyxovirus interferon antagonism and simian virus 5 replicationQ34340752
C-terminal region of STAT-1alpha is not necessary for its ubiquitination and degradation caused by mumps virus V proteinQ34351828
The rule of six, a basic feature for efficient replication of Sendai virus defective interfering RNA.Q36651219
A short peptide at the amino terminus of the Sendai virus C protein acts as an independent element that induces STAT1 instabilityQ36684288
The Newcastle disease virus V protein binds zincQ38300694
Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoterQ39548682
Sendai virus blocks alpha interferon signaling to signal transducers and activators of transcriptionQ39589711
Involvement of the zinc-binding capacity of Sendai virus V protein in viral pathogenesisQ39592941
The V protein of simian virus 5 inhibits interferon signalling by targeting STAT1 for proteasome-mediated degradationQ39596942
Nipah virus V protein evades alpha and gamma interferons by preventing STAT1 and STAT2 activation and nuclear accumulationQ39685810
STAT3 ubiquitylation and degradation by mumps virus suppress cytokine and oncogene signalingQ39752565
STAT protein interference and suppression of cytokine signal transduction by measles virus V proteinQ39787663
Newcastle disease virus V protein is associated with viral pathogenesis and functions as an alpha interferon antagonistQ39796662
Newcastle disease virus V protein is a determinant of host range restrictionQ39864222
Hendra virus V protein inhibits interferon signaling by preventing STAT1 and STAT2 nuclear accumulationQ40012127
Measles virus V protein blocks interferon (IFN)-alpha/beta but not IFN-gamma signaling by inhibiting STAT1 and STAT2 phosphorylationQ40640005
Recovery of paramyxovirus simian virus 5 with a V protein lacking the conserved cysteine-rich domain: the multifunctional V protein blocks both interferon-beta induction and interferon signalingQ40683477
All four Sendai Virus C proteins bind Stat1, but only the larger forms also induce its mono-ubiquitination and degradationQ40729242
The V protein of human parainfluenza virus 2 antagonizes type I interferon responses by destabilizing signal transducer and activator of transcription 2.Q40808240
C terminal CYS-RICH region of mumps virus structural V protein correlates with block of interferon alpha and gamma signal transduction pathway through decrease of STAT 1-alphaQ40809963
P433issue13
P304page(s)8591-8601
P577publication date2005-07-01
P1433published inJournal of VirologyQ1251128
P1476titleIdentification of paramyxovirus V protein residues essential for STAT protein degradation and promotion of virus replication
P478volume79

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cites work (P2860)
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