Comprehensive mutational analysis of the Moloney murine leukemia virus envelope protein

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Comprehensive mutational analysis of the Moloney murine leukemia virus envelope protein is …
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scholarly articleQ13442814

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P356DOI10.1128/JVI.75.23.11851-11862.2001
P932PMC publication ID114771
P698PubMed publication ID11689666
P5875ResearchGate publication ID11663080

P2093author name stringP O Brown
R A Crowley
S M Rothenberg
L C Laurent
M N Olsen
P2860cites workMany random sequences functionally replace the secretion signal sequence of yeast invertaseQ68925585
The amino-terminal charge and core region hydrophobicity interdependently contribute to the function of signal sequencesQ71246507
Target site selection in transposition of phage MuQ72794146
Structure of influenza haemagglutinin at the pH of membrane fusionQ27730888
Retrovirus envelope domain at 1.7 angstrom resolutionQ27732659
Structure of a murine leukemia virus receptor-binding glycoprotein at 2.0 angstrom resolutionQ27742825
Structure of the hemagglutinin precursor cleavage site, a determinant of influenza pathogenicity and the origin of the labile conformationQ27766025
Folding and assembly of viral membrane proteinsQ27865318
Structure of the haemagglutinin membrane glycoprotein of influenza virus at 3 A resolutionQ28131812
A spring-loaded mechanism for the conformational change of influenza hemagglutininQ28646856
Role of hemagglutinin cleavage for the pathogenicity of influenza virus.Q30322358
Membrane fusion: the influenza paradigmQ30469241
Functional characterization of the human immunodeficiency virus type 1 genome by genetic footprintingQ31523975
Identification of a receptor-binding pocket on the envelope protein of friend murine leukemia virus.Q33646515
Characterization of the proline-rich region of murine leukemia virus envelope protein.Q33784874
Activation of a cell entry pathway common to type C mammalian retroviruses by soluble envelope fragmentsQ33794864
Receptor co-operation in retrovirus entry: recruitment of an auxiliary entry mechanism after retargeted bindingQ33886233
Efficiency and diversity of protein localization by random signal sequencesQ33909686
Detection of receptor-specific murine leukemia virus binding to cells by immunofluorescence analysisQ33932054
Studies of the membrane fusion activities of fusion peptide mutants of influenza virus hemagglutininQ35849518
Identification of a subdomain in the Moloney murine leukemia virus envelope protein involved in receptor bindingQ35857007
Analysis of the murine leukemia virus R peptide: delineation of the molecular determinants which are important for its fusion inhibition activityQ35898515
High-resolution functional mapping of a cloned gene by genetic footprintingQ35996011
Quality control in the endoplasmic reticulum: folding and misfolding of vesicular stomatitis virus G protein in cells and in vitroQ36223730
Sequence-specific antibodies show that maturation of Moloney leukemia virus envelope polyprotein involves removal of a COOH-terminal peptideQ36373246
Modifications in the binding domain of avian retrovirus envelope protein to redirect the host range of retroviral vectorsQ36622965
Function of the cytoplasmic domain of a retroviral transmembrane protein: p15E-p2E cleavage activates the membrane fusion capability of the murine leukemia virus Env proteinQ36629882
pH-independent murine leukemia virus ecotropic envelope-mediated cell fusion: implications for the role of the R peptide and p12E TM in viral entryQ36633601
Mutational analysis of the envelope gene of Moloney murine leukemia virusQ36648415
Receptor choice determinants in the envelope glycoproteins of amphotropic, xenotropic, and polytropic murine leukemia virusesQ36691708
Mutational analysis of the N-linked glycosylation sites of the SU envelope protein of Moloney murine leukemia virusQ36698884
An amino-terminal fragment of the Friend murine leukemia virus envelope glycoprotein binds the ecotropic receptorQ36796983
Identification and characterization of a widely expressed phosphate transporter/retrovirus receptor familyQ36806076
Influenza hemagglutinin is spring-loaded by a metastable native conformationQ36809584
Secretion-defective mutations in the signal sequence for Saccharomyces cerevisiae invertaseQ36916922
The role of envelope glycoprotein processing in murine leukemia virus infectionQ36918689
Topography of murine leukemia virus envelope proteins: characterization of transmembrane componentsQ36932857
Kinetic and modeling studies of subsites S4-S3' of Moloney murine leukemia virus proteaseQ38307096
Receptor-mediated Moloney murine leukemia virus entry can occur independently of the clathrin-coated-pit-mediated endocytic pathway.Q38323885
The hypervariable domain of the murine leukemia virus surface protein tolerates large insertions and deletions, enabling development of a retroviral particle display system.Q39551618
Functional characterization of the N termini of murine leukemia virus envelope proteinsQ39602502
Mutational analysis of the fusion peptide of Moloney murine leukemia virus transmembrane protein p15EQ39642472
Receptor-binding domain of murine leukemia virus envelope glycoproteins.Q39868615
Functional dissection of the Moloney murine leukemia virus envelope protein gp70.Q39878576
Functional analysis of the cytoplasmic tail of Moloney murine leukemia virus envelope proteinQ39879338
Localization of the labile disulfide bond between SU and TM of the murine leukemia virus envelope protein complex to a highly conserved CWLC motif in SU that resembles the active-site sequence of thiol-disulfide exchange enzymesQ39881687
Thermolysin activation mutants with changes in the fusogenic region of an influenza virus hemagglutininQ40042585
The presence of disulfide-linked gp70-pl5(E) complexes in AKR murine leukemia virusQ40115195
Signal peptides: exquisitely designed transport promotersQ40565700
Signal sequence recognition and protein targeting to the endoplasmic reticulum membraneQ40611469
Mutational analysis of the putative receptor-binding domain of Moloney murine leukemia virus glycoprotein gp70.Q40868918
Identification of regions in the Moloney murine leukemia virus SU protein that tolerate the insertion of an integrin-binding peptideQ40892876
Membrane fusion by influenza hemagglutininQ41125215
Analysis of mutations within the cytoplasmic domain of the Moloney murine leukemia virus transmembrane proteinQ41133617
Mutations of conserved cysteine residues in the CWLC motif of the oncoretrovirus SU protein affect maturation and translocationQ41372415
Tissue-specific targeting of retroviral vectors through ligand-receptor interactionsQ41428152
Conserved structural features in the interaction between retroviral surface and transmembrane glycoproteins?Q41861703
A putative murine ecotropic retrovirus receptor gene encodes a multiple membrane-spanning protein and confers susceptibility to virus infectionQ42798292
Episomal vectors rapidly and stably produce high-titer recombinant retrovirusQ42810400
A temperature-sensitive mutation constructed by "linker insertion" mutagenesisQ44325479
Mutational analysis of the fusion peptide of the human immunodeficiency virus type 1: identification of critical glycine residues.Q45771113
Mutational analysis of the substrate binding pocket of murine leukemia virus protease and comparison with human immunodeficiency virus proteasesQ45790361
Studies with inhibitors of oligosaccharide processing indicate a functional role for complex sugars in the transport and proteolysis of friend mink cell focus-inducing murine leukemia virus envelope proteinsQ45796295
Fusion mutants of the influenza virus hemagglutinin glycoproteinQ45828281
Maturation of murine leukemia virus env proteins in the absence of other viral proteinsQ45838350
[28] Linker insertion mutagenesis as probe of structure-function relationshipsQ58462676
P4510describes a project that usesImageQuantQ112270642
P433issue23
P407language of work or nameEnglishQ1860
P921main subjectmurine leukemia virusQ673848
mutational analysisQ1955810
leukemiaQ29496
Moloney murine leukemia virusQ61764092
P304page(s)11851-11862
P577publication date2001-12-01
P1433published inJournal of VirologyQ1251128
P1476titleComprehensive mutational analysis of the Moloney murine leukemia virus envelope protein
P478volume75