Major peptide autoepitopes for nucleosome-specific T cells of human lupus

scientific article

Major peptide autoepitopes for nucleosome-specific T cells of human lupus is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI6801
P932PMC publication ID408421
P698PubMed publication ID10430616

P2093author name stringL Lu
D T Boumpas
A Kaliyaperumal
S K Datta
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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytesQ36363024
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Nucleosomal peptide epitopes for nephritis-inducing T helper cells of murine lupusQ36366783
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Promiscuous presentation and recognition of nucleosomal autoepitopes in lupus: role of autoimmune T cell receptor alpha chainQ36400210
Systemic exposure to irradiated apoptotic cells induces autoantibody productionQ36401434
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Roles of interferon-gamma and interleukin-4 in murine lupusQ37365961
Interferon-gamma is required for lupus-like disease and lymphoaccumulation in MRL-lpr miceQ37377479
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Junctional region sequences of T-cell receptor beta-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: possible selection by cationic autoantigensQ37644134
Pathogenic autoantibodies are routinely generated during the response to foreign antigen: a paradigm for autoimmune diseaseQ37708458
Predominant naturally processed peptides bound to HLA-DR1 are derived from MHC-related molecules and are heterogeneous in sizeQ39229154
Several common HLA-DR types share largely overlapping peptide binding repertoiresQ41052906
Specific T cell recognition of minimally homologous peptides: evidence for multiple endogenous ligandsQ41342616
Self antigens and epitope spreading in systemic autoimmunityQ41564944
Heterogeneity of intracellular cytokine synthesis at the single-cell level in polarized T helper 1 and T helper 2 populationsQ41840721
Strength of TCR signal determines the costimulatory requirements for Th1 and Th2 CD4+ T cell differentiationQ42060819
Continuous administration of anti-interleukin 10 antibodies delays onset of autoimmunity in NZB/W F1 miceQ42942093
T cell receptor alpha/beta expressing double-negative (CD4-/CD8-) and CD4+ T helper cells in humans augment the production of pathogenic anti-DNA autoantibodies associated with lupus nephritisQ44381577
Degenerate recognition of a dissimilar antigenic peptide by myelin basic protein-reactive T cells. Implications for thymic education and autoimmunityQ46792549
Interaction between CD40 and its ligand gp39 in the development of murine lupus nephritis.Q52054451
Flow-Cytometric Assessment ofin VivoCytokine-Producing Monocytes in HIV-Infected PatientsQ57723266
Reliability and validity of six systems for the clinical assessment of disease activity in systemic lupus erythematosusQ57740770
A single TCR antagonist peptide inhibits experimental allergic encephalomyelitis mediated by a diverse T cell repertoireQ63535316
Dual reactivity of several monoclonal anti-nucleosome autoantibodies for double-stranded DNA and a short segment of histone H3Q64389360
The NZB X SWR model of lupus nephritis. II. Autoantibodies deposited in renal lesions show a distinctive and restricted idiotypic diversityQ68809502
CD4+ T cell lines with selective patterns of autoreactivity as well as CD4- CD8- T helper cell lines augment the production of idiotypes shared by pathogenic anti-DNA autoantibodies in the NZB x SWR model of lupus nephritisQ70049950
Presence of nucleosome-restricted antibodies in patients with systemic lupus erythematosusQ71781135
Glomerular binding activity in MRL lpr serum consists of antibodies that bind to a DNA/histone/type IV collagen complexQ72575081
Roles of IL-4 and IL-12 in the development of lupus in NZB/W F1 miceQ73026032
Mapping of linear histone regions exposed at the surface of the nucleosome in solutionQ73876602
Histone-specific Th0 and Th1 clones derived from systemic lupus erythematosus patients induce double-stranded DNA antibody productionQ73994619
Predictable TCR antigen recognition based on peptide scans leads to the identification of agonist ligands with no sequence homologyQ74477147
Genetic susceptibility to systemic lupus erythematosusQ74578130
A very high level of crossreactivity is an essential feature of the T-cell receptorQ77324273
Antigen-specific therapy of murine lupus nephritis using nucleosomal peptides: tolerance spreading impairs pathogenic function of autoimmune T and B cellsQ77404750
Susceptibility to lupus nephritis in the NZB/W model systemQ77892082
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)345-355
P577publication date1999-08-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleMajor peptide autoepitopes for nucleosome-specific T cells of human lupus.
P478volume104

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