Rational design of a Corynebacterium glutamicum pantothenate production strain and its characterization by metabolic flux analysis and genome-wide transcriptional profiling

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Rational design of a Corynebacterium glutamicum pantothenate production strain and its characterization by metabolic flux analysis and genome-wide transcriptional profiling is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/AEM.71.6.3255-3268.2005
P932PMC publication ID1151861
P698PubMed publication ID15933028

P50authorAlfred PühlerQ1488595
Jörn KalinowskiQ30420819
Veronika ElišákováQ80265617
Andreas TauchQ108009077
P2093author name stringIris Brune
Miroslav Pátek
Nic D Lindley
Christophe Chassagnole
Andrea T Hüser
Armel Guyonvarch
Muriel Merkamm
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The complete Corynebacterium glutamicum ATCC 13032 genome sequence and its impact on the production of L-aspartate-derived amino acids and vitaminsQ33968067
Pathway analysis and metabolic engineering in Corynebacterium glutamicum.Q34081461
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Thioesterase II of Escherichia coli plays an important role in 3-hydroxydecanoic acid productionQ35661205
Valine is a precursor of propionyl-CoAQ36160588
Triggering mechanism of L-glutamate overproduction by DtsR1 in coryneform bacteria.Q36289827
Expression vectors employing lambda-, trp-, lac-, and lpp-derived promoters.Q39303452
Expression of the Corynebacterium glutamicum panD gene encoding L-aspartate-alpha-decarboxylase leads to pantothenate overproduction in Escherichia coliQ39481203
D-Pantothenate synthesis in Corynebacterium glutamicum and use of panBC and genes encoding L-valine synthesis for D-pantothenate overproductionQ39481594
Identification of glyA (encoding serine hydroxymethyltransferase) and its use together with the exporter ThrE to increase L-threonine accumulation by Corynebacterium glutamicumQ39650143
Linking central metabolism with increased pathway flux: L-valine accumulation by Corynebacterium glutamicumQ39653402
Leucine synthesis in Corynebacterium glutamicum: enzyme activities, structure of leuA, and effect of leuA inactivation on lysine synthesis.Q39913837
Isoleucine synthesis in Corynebacterium glutamicum: molecular analysis of the ilvB-ilvN-ilvC operonQ39936735
A Corynebacterium glutamicum gene encoding a two-domain protein similar to biotin carboxylases and biotin-carboxyl-carrier proteinsQ42637087
A general method for introducing a series of mutations into cloned DNA using the polymerase chain reactionQ43919784
The alanine racemase gene alr is an alternative to antibiotic resistance genes in cloning systems for industrial Corynebacterium glutamicum strainsQ44120600
Carbon flux analysis in a pantothenate overproducing Corynebacterium glutamicum strain.Q44144796
3-Phosphoglycerate dehydrogenase from Corynebacterium glutamicum: the C-terminal domain is not essential for activity but is required for inhibition by L-serineQ44238970
Genome-wide analysis of the L-methionine biosynthetic pathway in Corynebacterium glutamicum by targeted gene deletion and homologous complementationQ44568863
Genome-based analysis of biosynthetic aminotransferase genes of Corynebacterium glutamicumQ44568867
Characterisation of the enzyme activities involved in the valine biosynthetic pathway in a valine-producing strain of Corynebacterium glutamicumQ44568868
Development of a Corynebacterium glutamicum DNA microarray and validation by genome-wide expression profiling during growth with propionate as carbon sourceQ44677457
Chaotic mixer improves microarray hybridizationQ47233156
Analysis of the leuB gene from Corynebacterium glutamicumQ48027814
THE RELATIONSHIPS BETWEEN SUBSTRATES AND ENZYMES OF GLYCOLYSIS IN BRAINQ51279814
A heat shock following electroporation induces highly efficient transformation of Corynebacterium glutamicum with xenogeneic plasmid DNA.Q52537077
‘Integron’-bearing vectors: a method suitable for stable chromosomal integration in highly restrictive CorynebacteriaQ54690128
Free energy changes of the argininosuccinate synthetase reaction and of the hydrolysis of the inner pyrophosphate bond of adenosine triphosphate.Q55037326
Interspecies electro-transformation in CorynebacteriaQ67282822
Serine transhydroxymethylase: evidence for a sequential random mechanismQ67547500
Two families of acyl-CoA thioesterases in ArabidopsisQ73425215
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectCorynebacterium glutamicumQ292314
P304page(s)3255-3268
P577publication date2005-06-01
P1433published inApplied and Environmental MicrobiologyQ4781593
P1476titleRational design of a Corynebacterium glutamicum pantothenate production strain and its characterization by metabolic flux analysis and genome-wide transcriptional profiling
P478volume71

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