scholarly article | Q13442814 |
P50 | author | Laurent R Gauthier | Q56600293 |
Christine Granotier-Beckers | Q60013524 | ||
Denis Serge François Biard | Q67543180 | ||
Francois Boussin | Q67975078 | ||
Gaelle Pennarun | Q73218802 | ||
P2093 | author name string | Françoise Hoffschir | |
Patrick Mailliet | |||
Deborah Revaud | |||
P2860 | cites work | Mammalian telomeres end in a large duplex loop | Q22009893 |
The Bloom's and Werner's syndrome proteins are DNA structure-specific helicases | Q24291390 | ||
Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a) | Q24293520 | ||
ERCC1/XPF removes the 3' overhang from uncapped telomeres and represses formation of telomeric DNA-containing double minute chromosomes | Q24302611 | ||
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats | Q24339608 | ||
Chromosomal instability at common fragile sites in Seckel syndrome | Q24533727 | ||
Preferential binding of a G-quadruplex ligand to human chromosome ends. | Q24815673 | ||
Homologous recombination generates T-loop-sized deletions at human telomeres | Q28116970 | ||
Cell cycle-dependent role of MRN at dysfunctional telomeres: ATM signaling-dependent induction of nonhomologous end joining (NHEJ) in G1 and resection-mediated inhibition of NHEJ in G2 | Q42117260 | ||
Werner's syndrome protein is phosphorylated in an ATR/ATM-dependent manner following replication arrest and DNA damage induced during the S phase of the cell cycle | Q44357501 | ||
Circular chromosome formation in a fission yeast mutant defective in two ATM homologues | Q48016421 | ||
Werner syndrome protein, the MRE11 complex and ATR: menage-à-trois in guarding genome stability during DNA replication? | Q48026242 | ||
Telomerase maintains telomere structure in normal human cells. | Q52551445 | ||
Double hybridization signals on the chromatid revealed by telomeric probes | Q73180846 | ||
The Bloom's syndrome helicase unwinds G4 DNA | Q77387768 | ||
The DNA damage machinery and homologous recombination pathway act consecutively to protect human telomeres | Q79365400 | ||
Dynamic roles for G4 DNA in the biology of eukaryotic cells | Q79405617 | ||
A splicing mutation affecting expression of ataxia-telangiectasia and Rad3-related protein (ATR) results in Seckel syndrome | Q28183834 | ||
Recruitment of the cell cycle checkpoint kinase ATR to chromatin during S-phase | Q28243999 | ||
Resolution of sister telomere association is required for progression through mitosis | Q28254648 | ||
Shelterin: the protein complex that shapes and safeguards human telomeres | Q28272546 | ||
Strand-Specific Postreplicative Processing of Mammalian Telomeres | Q28315729 | ||
DNA ligase IV-dependent NHEJ of deprotected mammalian telomeres in G1 and G2 | Q28509254 | ||
ATR disruption leads to chromosomal fragmentation and early embryonic lethality | Q28591433 | ||
p53- and ATM-dependent apoptosis induced by telomeres lacking TRF2 | Q28609749 | ||
ATR: an essential regulator of genome integrity | Q29547883 | ||
Functional human telomeres are recognized as DNA damage in G2 of the cell cycle | Q33227804 | ||
Untangling the relationships between DNA repair pathways by silencing more than 20 DNA repair genes in human stable clones. | Q33283854 | ||
Protection of telomeres through independent control of ATM and ATR by TRF2 and POT1. | Q33293671 | ||
Dysfunctional telomeres activate an ATM-ATR-dependent DNA damage response to suppress tumorigenesis | Q33303185 | ||
Ataxia-telangiectasia and Rad3-related and DNA-dependent protein kinase cooperate in G2 checkpoint activation by the DNA strand-breaking nucleoside analogue 2'-C-cyano-2'-deoxy-1-beta-D-arabino-pentofuranosylcytosine | Q33315217 | ||
ATM and ATR make distinct contributions to chromosome end protection and the maintenance of telomeric DNA in Arabidopsis | Q34009139 | ||
Drosophila ATM and ATR checkpoint kinases control partially redundant pathways for telomere maintenance | Q34085000 | ||
Elevated telomere-telomere recombination in WRN-deficient, telomere dysfunctional cells promotes escape from senescence and engagement of the ALT pathway | Q34116956 | ||
Apollo, an Artemis-related nuclease, interacts with TRF2 and protects human telomeres in S phase | Q34531241 | ||
Genetic control of telomere integrity in Schizosaccharomyces pombe: rad3(+) and tel1(+) are parts of two regulatory networks independent of the downstream protein kinases chk1(+) and cds1(+). | Q34607461 | ||
Telomere binding of checkpoint sensor and DNA repair proteins contributes to maintenance of functional fission yeast telomeres. | Q34615813 | ||
Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice | Q34997279 | ||
Phosphorylation of the Bloom's syndrome helicase and its role in recovery from S-phase arrest | Q35544616 | ||
Functional links between telomeres and proteins of the DNA-damage response | Q35853775 | ||
Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination | Q36627883 | ||
Flap endonuclease 1 contributes to telomere stability | Q36632697 | ||
The ATR pathway: fine-tuning the fork | Q36832714 | ||
How telomeres are replicated | Q36948200 | ||
DNA damage response at functional and dysfunctional telomeres | Q37058277 | ||
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication | Q37297007 | ||
The mre11 complex and the response to dysfunctional telomeres | Q37374755 | ||
Interactions of TLC1 (which encodes the RNA subunit of telomerase), TEL1, and MEC1 in regulating telomere length in the yeast Saccharomyces cerevisiae | Q38321503 | ||
Heterogeneity in telomere length of human chromosomes. | Q39426746 | ||
Apoptosis related to telomere instability and cell cycle alterations in human glioma cells treated by new highly selective G-quadruplex ligands. | Q40453428 | ||
Defective telomere lagging strand synthesis in cells lacking WRN helicase activity. | Q40481955 | ||
Seckel syndrome exhibits cellular features demonstrating defects in the ATR-signalling pathway. | Q40501657 | ||
ATR affecting cell radiosensitivity is dependent on homologous recombination repair but independent of nonhomologous end joining | Q40507919 | ||
X-ray-induced telomeric instability in Atm-deficient mouse cells | Q40580170 | ||
Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening | Q41121125 | ||
Role of ATM in the telomere response to the G-quadruplex ligand 360A. | Q41851639 | ||
P433 | issue | 9 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 2955-2963 | |
P577 | publication date | 2010-02-10 | |
P1433 | published in | Nucleic Acids Research | Q135122 |
P1476 | title | ATR contributes to telomere maintenance in human cells | |
P478 | volume | 38 |
Q46756203 | A stable RNA G-quadruplex within the 5'-UTR of Arabidopsis thaliana ATR mRNA inhibits translation. |
Q61811967 | ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition |
Q28117859 | ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres |
Q89520185 | ATM, ATR and DNA-PKcs kinases-the lessons from the mouse models: inhibition ≠ deletion |
Q90346173 | Alternative lengthening of telomeres: from molecular mechanisms to therapeutic outlooks |
Q39204805 | DNA Replication Origins and Fork Progression at Mammalian Telomeres |
Q36740850 | DNA damage signaling induced by the G-quadruplex ligand 12459 is modulated by PPM1D/WIP1 phosphatase |
Q84282108 | Dyskeratosis congenita |
Q38084623 | Fluorescent probes for G-quadruplex structures. |
Q26740026 | Hallmarks of progeroid syndromes: lessons from mice and reprogrammed cells |
Q38774203 | Mismatch repair enhances convergent transcription-induced cell death at trinucleotide repeats by activating ATR. |
Q35092634 | Molecular characterization of apoptosis induced by CARF silencing in human cancer cells |
Q42265703 | Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance. |
Q24619372 | Partial complementation of a DNA ligase I deficiency by DNA ligase III and its impact on cell survival and telomere stability in mammalian cells |
Q38943974 | Polymerase η suppresses telomere defects induced by DNA damaging agents |
Q39251262 | Primary microcephaly, impaired DNA replication, and genomic instability caused by compound heterozygous ATR mutations |
Q34672718 | Primordial dwarfism: overview of clinical and genetic aspects. |
Q39503969 | Rad51 and DNA-PKcs are involved in the generation of specific telomere aberrations induced by the quadruplex ligand 360A that impair mitotic cell progression and lead to cell death. |
Q35093084 | The replicometer is broken: telomeres activate cellular senescence in response to genotoxic stresses |
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