scholarly article | Q13442814 |
P2093 | author name string | L E Maquat | |
J Zhang | |||
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Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes | Q27860600 | ||
Gene-specific translational control of the yeast GCN4 gene by phosphorylation of eukaryotic initiation factor 2. | Q27934963 | ||
Primary structure of human triosephosphate isomerase | Q28118965 | ||
Structural features in eukaryotic mRNAs that modulate the initiation of translation | Q29547921 | ||
Translocation of a specific premessenger ribonucleoprotein particle through the nuclear pore studied with electron microscope tomography | Q31168507 | ||
Efficiency of reinitiation of translation on human immunodeficiency virus type 1 mRNAs is determined by the length of the upstream open reading frame and by intercistronic distance | Q34058977 | ||
Translational termination efficiency in mammals is influenced by the base following the stop codon. | Q34222816 | ||
Evidence that the decay of nucleus-associated nonsense mRNA for human triosephosphate isomerase involves nonsense codon recognition after splicing. | Q34361052 | ||
Nonsense mutations inhibit splicing of MVM RNA in cis when they interrupt the reading frame of either exon of the final spliced product. | Q34422154 | ||
When cells stop making sense: effects of nonsense codons on RNA metabolism in vertebrate cells. | Q34693550 | ||
Utilizing the GCN4 leader region to investigate the role of the sequence determinants in nonsense-mediated mRNA decay. | Q35851318 | ||
Dominant beta thalassaemia: molecular basis and pathophysiology | Q36089957 | ||
Modulation of tRNA(iMet), eIF-2, and eIF-2B expression shows that GCN4 translation is inversely coupled to the level of eIF-2.GTP.Met-tRNA(iMet) ternary complexes | Q36555932 | ||
Characterization of cis-acting sequences and decay intermediates involved in nonsense-mediated mRNA turnover | Q36566764 | ||
Effect of sequence context at stop codons on efficiency of reinitiation in GCN4 translational control | Q36644113 | ||
Requirements for intercistronic distance and level of eukaryotic initiation factor 2 activity in reinitiation on GCN4 mRNA vary with the downstream cistron | Q36650671 | ||
Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance | Q36666048 | ||
T cell receptor-beta mRNA splicing: regulation of unusual splicing intermediates | Q36676308 | ||
Nonsense mutations in the dihydrofolate reductase gene affect RNA processing | Q36769262 | ||
Termination-reinitiation occurs in the translation of mammalian cell mRNAs | Q36917860 | ||
Effect of upstream reading frames on translation efficiency in simian virus 40 recombinants | Q36917883 | ||
Distribution of reversing factor in reticulocyte lysates during active protein synthesis and on inhibition by heme deprivation or double-stranded RNA. | Q37576852 | ||
Low cytoplasmic mRNA levels of immunoglobulin kappa light chain genes containing nonsense codons correlate with inefficient splicing. | Q37636788 | ||
Nonsense-mediated mRNA decay in yeast | Q40663894 | ||
The second to last amino acid in the nascent peptide as a codon context determinant. | Q40790501 | ||
The immediate downstream codon strongly influences the efficiency of utilization of eukaryotic translation initiation codons. | Q40792763 | ||
The identity of the base following the stop codon determines the efficiency of in vivo translational termination in Escherichia coli | Q40805404 | ||
Evidence for degradation of mRNA encoding alpha-L-iduronidase in Hurler fibroblasts with premature termination alleles. | Q41433267 | ||
Mechanism of translation of the bicistronic mRNA encoding human papillomavirus type 16 E6-E7 genes | Q41438087 | ||
Defects in RNA splicing and the consequence of shortened translational reading frames | Q42590534 | ||
GCD10, a translational repressor of GCN4, is the RNA-binding subunit of eukaryotic translation initiation factor-3. | Q42675542 | ||
Maintenance of an open reading frame as an additional level of scrutiny during splice site selection | Q42689167 | ||
Dominant thalassemia-like phenotypes associated with mutations in exon 3 of the beta-globin gene | Q44734112 | ||
The skipping of constitutive exons in vivo induced by nonsense mutations | Q70554031 | ||
Nonsense mutations inhibit RNA splicing in a cell-free system: recognition of mutant codon is independent of protein synthesis | Q71046937 | ||
mRNA surveillance by the Caenorhabditis elegans smg genes | Q72234045 | ||
Nonsense codon mutations in the terminal exon of the beta-globin gene are not associated with a reduction in beta-mRNA accumulation: a mechanism for the phenotype of dominant beta-thalassemia | Q72372067 | ||
mRNA destabilization triggered by premature translational termination depends on at least three cis-acting sequence elements and one trans-acting factor | Q72921331 | ||
P433 | issue | 4 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 826-833 | |
P577 | publication date | 1997-02-01 | |
P1433 | published in | The EMBO Journal | Q1278554 |
P1476 | title | Evidence that translation reinitiation abrogates nonsense-mediated mRNA decay in mammalian cells | |
P478 | volume | 16 |
Q34638075 | A cell type-restricted mRNA surveillance pathway triggered by ribosome extension into the 3' untranslated region |
Q53037787 | A meta-analysis of nonsense mutations causing human genetic disease. |
Q42613411 | A minimal uORF within the HIV-1 vpu leader allows efficient translation initiation at the downstream env AUG. |
Q36283006 | A mutated human homologue to yeast Upf1 protein has a dominant-negative effect on the decay of nonsense-containing mRNAs in mammalian cells |
Q29616125 | A perfect message: RNA surveillance and nonsense-mediated decay |
Q45748088 | A premature termination codon in either exon of minute virus of mice P4 promoter-generated pre-mRNA can inhibit nuclear splicing of the intervening intron in an open reading frame-dependent manner |
Q29615731 | A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance |
Q33687737 | Allelic imbalance of somatic mutations in cancer genomes and transcriptomes. |
Q28138030 | Alternative splicing regulates the production of ARD-1 endoribonuclease and NIPP-1, an inhibitor of protein phosphatase-1, as isoforms encoded by the same gene |
Q28258466 | An activated 5' cryptic splice site in the human ALG3 gene generates a premature termination codon insensitive to nonsense-mediated mRNA decay in a new case of congenital disorder of glycosylation type Id (CDG-Id) |
Q35741768 | An alternative branch of the nonsense-mediated decay pathway |
Q47942411 | Analysis of the allele-specific expression of the mismatch repair gene MLH1 using a simple DHPLC-Based Method |
Q33778146 | At least one intron is required for the nonsense-mediated decay of triosephosphate isomerase mRNA: a possible link between nuclear splicing and cytoplasmic translation |
Q37219028 | BRCA2 T2722R is a deleterious allele that causes exon skipping |
Q42647080 | Binary specification of nonsense codons by splicing and cytoplasmic translation |
Q90975831 | Biological plasticity rescues target activity in CRISPR knock outs |
Q60054252 | Capitalizing on the heterogeneous effects of CFTR nonsense and frameshift variants to inform therapeutic strategy for cystic fibrosis |
Q39884109 | Chapter 9. Studying nonsense-mediated mRNA decay in mammalian cells |
Q24548063 | Cloning of Drosophila GCN5: conserved features among metazoan GCN5 family members |
Q79888560 | Comment on 'Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease' |
Q37847790 | Control of human beta-globin mRNA stability and its impact on beta-thalassemia phenotype. |
Q41242129 | Cytoplasmic mRNA for human triosephosphate isomerase is immune to nonsense-mediated decay despite forming polysomes |
Q37144701 | DMD exon 1 truncating point mutations: amelioration of phenotype by alternative translation initiation in exon 6. |
Q80063140 | Detection of novel NF1 mutations and rapid mutation prescreening with Pyrosequencing |
Q33760873 | Determinants of initiation codon selection during translation in mammalian cells |
Q90750969 | Divergent effects of translation termination factor eRF3A and nonsense-mediated mRNA decay factor UPF1 on the expression of uORF carrying mRNAs and ribosome protein genes |
Q42177138 | Early LQT2 nonsense mutation generates N-terminally truncated hERG channels with altered gating properties by the reinitiation of translation |
Q35618130 | Efficient downregulation of immunoglobulin mu mRNA with premature translation-termination codons requires the 5'-half of the VDJ exon |
Q28542512 | Eukaryotic initiation factor 4G suppresses nonsense-mediated mRNA decay by two genetically separable mechanisms |
Q28352632 | Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway |
Q35015725 | Evidence that translation reinitiation leads to a partially functional Menkes protein containing two copper-binding sites. |
Q24291834 | Expression of human BRE in multiple isoforms |
Q33718674 | Expression proteomics of UPF1 knockdown in HeLa cells reveals autoregulation of hnRNP A2/B1 mediated by alternative splicing resulting in nonsense-mediated mRNA decay |
Q91361715 | Homozygous frame shift variant in ATP7B exon 1 leads to bypass of nonsense-mediated mRNA decay and to a protein capable of copper export |
Q52359413 | ICE1 promotes the link between splicing and nonsense-mediated mRNA decay. |
Q73714452 | Identical germ-line mutations in the triosephosphate isomerase alleles of two brothers are associated with distinct clinical phenotypes |
Q44847065 | Identification and in silico analysis of novel von Hippel-Lindau (VHL) gene variants from a large population |
Q33888137 | Identifying the right stop: determining how the surveillance complex recognizes and degrades an aberrant mRNA. |
Q28365393 | Impaired heme binding and aggregation of mutant cystathionine beta-synthase subunits in homocystinuria |
Q38609884 | Infrequent translation of a nonsense codon is sufficient to decrease mRNA level |
Q33777524 | Initiation of protein synthesis in mammalian cells with codons other than AUG and amino acids other than methionine |
Q34361461 | Intron function in the nonsense-mediated decay of beta-globin mRNA: indications that pre-mRNA splicing in the nucleus can influence mRNA translation in the cytoplasm |
Q34123861 | Kaposi's sarcoma-associated herpesvirus K8beta is derived from a spliced intermediate of K8 pre-mRNA and antagonizes K8alpha (K-bZIP) to induce p21 and p53 and blocks K8alpha-CDK2 interaction |
Q37342090 | LQT2 nonsense mutations generate trafficking defective NH2-terminally truncated channels by the reinitiation of translation |
Q34363476 | Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay |
Q24613209 | Mechanism of escape from nonsense-mediated mRNA decay of human beta-globin transcripts with nonsense mutations in the first exon |
Q38568755 | Mechanism, factors, and physiological role of nonsense-mediated mRNA decay. |
Q28258107 | Mutations in the NDUFS4 gene of mitochondrial complex I alter stability of the splice variants |
Q55418726 | New insights into the interplay between the translation machinery and nonsense-mediated mRNA decay factors. |
Q41861800 | Nonsense codons trigger an RNA partitioning shift |
Q91688225 | Nonsense mutation-dependent reinitiation of translation in mammalian cells |
Q40552071 | Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay. |
Q50513971 | Nonsense mutations in the COL1A1 gene preferentially reduce nuclear levels of mRNA but not hnRNA in osteogenesis imperfecta type I cell strains. |
Q36731022 | Nonsense mutations in the rhodopsin gene that give rise to mild phenotypes trigger mRNA degradation in human cells by nonsense-mediated decay |
Q40496380 | Nonsense-mediated and nonstop decay of ribosomal protein S19 mRNA in Diamond-Blackfan anemia |
Q40005465 | Nonsense-mediated mRNA decay (NMD) mechanisms |
Q35118819 | Nonsense-mediated mRNA decay immunity can help identify human polycistronic transcripts |
Q37622077 | Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors |
Q29616134 | Nonsense-mediated mRNA decay: splicing, translation and mRNP dynamics |
Q28302705 | Organizing principles of mammalian nonsense-mediated mRNA decay |
Q28204082 | Pathological mutations of the human NDUFS4 gene of the 18-kDa (AQDQ) subunit of complex I affect the expression of the protein and the assembly and function of the complex |
Q47175773 | Plant upstream ORFs can trigger nonsense-mediated mRNA decay in a size-dependent manner. |
Q39003338 | Premature termination of SMARCB1 translation may be followed by reinitiation in schwannomatosis-associated schwannomas, but results in absence of SMARCB1 expression in rhabdoid tumors. |
Q93138965 | Quality and quantity control of gene expression by nonsense-mediated mRNA decay |
Q33546909 | RNA surveillance. Unforeseen consequences for gene expression, inherited genetic disorders and cancer |
Q38864762 | Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity |
Q89984125 | SRSF7 maintains its homeostasis through the expression of Split-ORFs and nuclear body assembly |
Q33707306 | Should we kill the messenger? The role of the surveillance complex in translation termination and mRNA turnover |
Q46078682 | Structural insights on pathogenic effects of novel mutations causing pyruvate carboxylase deficiency. |
Q80187795 | The 185delAG mutation (c.68_69delAG) in the BRCA1 gene triggers translation reinitiation at a downstream AUG codon |
Q77525539 | The association of nonsense codons with exon skipping |
Q24678250 | The canonical UPF1-dependent nonsense-mediated mRNA decay is inhibited in transcripts carrying a short open reading frame independent of sequence context |
Q27014757 | The dharma of nonsense-mediated mRNA decay in mammalian cells |
Q33610885 | The impact of CFNS-causing EFNB1 mutations on ephrin-B1 function |
Q24817131 | The importance of being divisible by three in alternative splicing |
Q28575026 | The nonsense-mediated decay pathway and mutually exclusive expression of alternatively spliced FGFR2IIIb and -IIIc mRNAs |
Q40379554 | The position of premature termination codons in the hepatocyte nuclear factor -1 beta gene determines susceptibility to nonsense-mediated decay |
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Q39452112 | The role of nuclear cap binding protein Cbc1p of yeast in mRNA termination and degradation |
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Q74471693 | Translation is required to remove Y14 from mRNAs in the cytoplasm |
Q34075932 | Translational competence of ribosomes released from a premature termination codon is modulated by NMD factors |
Q42640783 | Translational regulation via 5' mRNA leader sequences revealed by mutational analysis of the Arabidopsis translation initiation factor subunit eIF3h |
Q35125501 | What determines whether mammalian ribosomes resume scanning after translation of a short upstream open reading frame? |
Q38128469 | mRNA quality control pathways in Saccharomyces cerevisiae |
Q33665734 | mRNA surveillance in eukaryotes: kinetic proofreading of proper translation termination as assessed by mRNP domain organization? |
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