Towards building a chromosome segregation machine.

scientific article

Towards building a chromosome segregation machine. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1038/NATURE08912
P932PMC publication ID2879044
P698PubMed publication ID20110988
P5875ResearchGate publication ID41174266

P50authorAjit P JoglekarQ56256933
Kerry BloomQ38319817
P2093author name stringAjit Joglekar
Kerry Bloom
P2860cites workThe kinetochore is an enhancer of pericentric cohesin bindingQ21092825
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CCAN makes multiple contacts with centromeric DNA to provide distinct pathways to the outer kinetochoreQ24324027
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The Dam1 kinetochore complex harnesses microtubule dynamics to produce force and movementQ27933739
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The yeast DASH complex forms closed rings on microtubules.Q27935179
Microtubule polymerization dynamicsQ28259930
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A polymeric protein anchors the chromosomal origin/ParB complex at a bacterial cell poleQ28485824
Two distinct pathways remove mammalian cohesin from chromosome arms in prophase and from centromeres in anaphaseQ28609170
De novo kinetochore assembly requires the centromeric histone H3 variant.Q28941168
Kinetochore attachments require an interaction between unstructured tails on microtubules and Ndc80(Hec1).Q30431323
Protein architecture of the human kinetochore microtubule attachment siteQ30436130
The condensin I subunit Barren/CAP-H is essential for the structural integrity of centromeric heterochromatin during mitosisQ30476289
In search of an optimal ring to couple microtubule depolymerization to processive chromosome motionsQ30480865
Different assemblies of the DAM1 complex follow shortening microtubules by distinct mechanisms.Q30481907
The Dam1 ring binds microtubules strongly enough to be a processive as well as energy-efficient coupler for chromosome motionQ30483984
Condensin regulates the stiffness of vertebrate centromeresQ30487316
DNA relaxation dynamics as a probe for the intracellular environment.Q30488160
The Ndc80 kinetochore complex forms load-bearing attachments to dynamic microtubule tips via biased diffusionQ30490445
First-principles calculation of DNA looping in tethered particle experimentsQ30508525
Processive translocation and DNA unwinding by individual RecBCD enzyme moleculesQ30980458
Micromanipulation of chromosomes reveals that cohesion release during cell division is gradual and does not require tensionQ31135231
Gold-nanoparticle-assisted laser perturbation of chromatin assembly reveals unusual aspects of nuclear architecture within living cellsQ33284379
Dynamics of chromatin decondensation reveals the structural integrity of a mechanically prestressed nucleusQ33343962
Persistent mechanical linkage between sister chromatids throughout anaphaseQ33873755
Sequence-directed DNA export guides chromosome translocation during sporulation in Bacillus subtilis.Q33911060
Recruitment of SMC by ParB-parS organizes the origin region and promotes efficient chromosome segregationQ33943503
Proteolysis of mitotic chromosomes induces gradual and anisotropic decondensation correlated with a reduction of elastic modulus and structural sensitivity to rarely cutting restriction enzymesQ34298302
DNA topoisomerase II is required at the time of mitosis in yeastQ34564154
Isolation of a yeast centromere and construction of functional small circular chromosomesQ34714350
The structure of histone-depleted metaphase chromosomesQ34741905
Toward a molecular structure of the eukaryotic kinetochore.Q34877325
Entropy-driven spatial organization of highly confined polymers: lessons for the bacterial chromosomeQ34887137
Polymer motors: pushing out the front and pulling up the backQ35295016
The enhancement of pericentromeric cohesin association by conserved kinetochore components promotes high-fidelity chromosome segregation and is sensitive to microtubule-based tensionQ35615980
Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells.Q53635877
Cell biology: chromosome territories.Q55042988
A Dam1-based artificial kinetochore is sufficient to promote chromosome segregation in budding yeastQ57887249
Partition mechanism of F plasmid: Two plasmid gene-encoded products and a cis-acting region are involved in partitionQ67265334
Transcription against an applied forceQ71593517
Measurement of lactose repressor-mediated loop formation and breakdown in single DNA moleculesQ72417475
Transient sister chromatid separation and elastic deformation of chromosomes during mitosis in budding yeastQ73990285
Cohesins bind to preferential sites along yeast chromosome III, with differential regulation along arms versus the centric regionQ78066772
Nucleosome chiral transition under positive torsional stress in single chromatin fibersQ80571133
Allosteric control of ribozyme catalysis by using DNA constraintsQ81312624
Grasping at originsQ82012643
tRNA genes as chromatin barriersQ82735335
Freely relaxing polymers remember how they were straightenedQ83723139
Structure, dynamics, and evolution of centromeric nucleosomesQ36012484
Displacement and re-accumulation of centromeric cohesin during transient pre-anaphase centromere splittingQ36138160
The 2 micron plasmid purloins the yeast cohesin complex: a mechanism for coupling plasmid partitioning and chromosome segregation?Q36325654
Budding yeast chromosome structure and dynamics during mitosisQ36381078
Pericentric chromatin is organized into an intramolecular loop in mitosisQ36453590
At the heart of the chromosome: SMC proteins in actionQ36457726
Coupling meiotic chromosome axis integrity to recombination.Q36510002
The centromere-kinetochore complex: a repeat subunit modelQ36529852
Dynamics of single-motor molecules: the thermal ratchet modelQ36772498
Large-sized polysomes in Chironomus tentans salivary glands and their relation to Balbiani ring 75S RNAQ36791720
SpoIIIE strips proteins off the DNA during chromosome translocation.Q36802831
Genetic manipulation of centromere functionQ36843287
Mechanisms of mitotic spindle assembly and functionQ37085042
Kinetochore stretching inactivates the spindle assembly checkpointQ37106715
Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activityQ37106724
Structural biology of plasmid partition: uncovering the molecular mechanisms of DNA segregationQ37143528
The bacteriophage DNA packaging motorQ37237759
Fibrils connect microtubule tips with kinetochores: a mechanism to couple tubulin dynamics to chromosome motion.Q37353009
Recruiting a microtubule-binding complex to DNA directs chromosome segregation in budding yeastQ37363489
Kinetochore-microtubule attachment relies on the disordered N-terminal tail domain of Hec1.Q37365711
Interaction of the histone (H3-H4)2 tetramer of the nucleosome with positively supercoiled DNA minicircles: Potential flipping of the protein from a left- to a right-handed superhelical formQ37427611
Controlling proteins through molecular springsQ37470633
Theoretical problems related to the attachment of microtubules to kinetochoresQ37545521
Use of an inducible site-specific recombinase to probe the structure of protein-DNA complexes involved in F plasmid partition in Escherichia coliQ38310900
In vivo protein architecture of the eukaryotic kinetochore with nanometer scale accuracyQ39413546
The forces that move chromosomes in mitosisQ39653525
Pericentric chromatin is an elastic component of the mitotic spindle.Q41949694
Centromeric nucleosomes induce positive DNA supercoilsQ42113262
Partition of unit-copy miniplasmids to daughter cells. II. The partition region of miniplasmid P1 encodes an essential protein and a centromere-like site at which it actsQ44431395
Torsional rigidity of positively and negatively supercoiled DNAQ44449301
The hydration dynamics of polyelectrolyte gels with applications to cell motility and drug deliveryQ46731090
Yeast centromere DNA is in a unique and highly ordered structure in chromosomes and small circular minichromosomesQ48404475
Force and velocity measured for single molecules of RNA polymerase.Q52232915
The physics behind the larger scale organization of DNA in eukaryotes.Q53386109
Cell biology. Bacteria's new bones.Q53506092
P433issue7280
P407language of work or nameEnglishQ1860
P304page(s)446-456
P577publication date2010-01-01
P1433published inNatureQ180445
P1476titleTowards building a chromosome segregation machine
P478volume463

Reverse relations

cites work (P2860)
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Q53068625Forces due to curving protofilaments in microtubules.
Q96954789Genome Segregation by the Venus Flytrap Mechanism: Probing the Interaction Between the ParF ATPase and the ParG Centromere Binding Protein
Q40856838Getting to the heart of an unusual kinetochore
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Q43537862Meiotic kinetochores get pushed aside by a CLS act.
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Q39446816Mitotic spindle: kinetochore fibers hold on tight to interpolar bundles
Q40856845Molecular Anatomy of ParA-ParA and ParA-ParB Interactions during Plasmid Partitioning
Q36525635Molecular requirements for the formation of a kinetochore-microtubule interface by Dam1 and Ndc80 complexes
Q34558046Multiple opposing constraints govern chromosome interactions during meiosis
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Q50624761Tracking of chromosome dynamics in live Streptococcus pneumoniae reveals that transcription promotes chromosome segregation.
Q36466600Uncoupling of nucleotide hydrolysis and polymerization in the ParA protein superfamily disrupts DNA segregation dynamics

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