Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign.

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Sickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign. is …
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scholarly articleQ13442814

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P356DOI10.1111/BJH.12650
P8608Fatcat IDrelease_4vr6bxuucjfvnnrla2nnxhj3rq
P932PMC publication ID4094128
P698PubMed publication ID24224700
P5875ResearchGate publication ID258512067

P50authorPaola SebastianiQ7132103
Martin H SteinbergQ37380250
Hazem A. GhabbourQ42152782
David H K ChuiQ66829380
P2093author name stringAbdulrahman Alsultan
Waleed H Albuali
Amein K Al-Ali
Mohammed K Alabdulaali
Paula J Griffin
Ahmed M Alsuliman
P2860cites workSilent cerebral infarcts: a review on a prevalent and progressive cause of neurologic injury in sickle cell anemiaQ27026479
Hypersplenism in homozygous sickle-cell disease in Saudi ArabiaQ33411080
Fetal haemoglobin levels and haematological characteristics of compound heterozygotes for haemoglobin S and deletional hereditary persistence of fetal haemoglobinQ34053823
Fetal hemoglobin in sickle cell anemia: genetic studies of the Arab-Indian haplotypeQ34610322
Sickle cell leg ulcers: associations with haemolysis and SNPs in Klotho, TEK and genes of the TGF-beta/BMP pathwayQ35191429
Sickle beta 0 thalassemia in Eastern Saudi ArabiaQ35203514
A rapid and reliable 7-deletion multiplex polymerase chain reaction assay for alpha-thalassemiaQ74144407
Hb H hydrops fetalis syndrome associated with the interaction of two common determinants of alpha thalassaemia (--MED/(alpha)TSaudi(alpha))Q74167056
Splenic function in children with sickle cell disease: two different patterns in Saudi ArabiaQ93623919
Benign sickle-cell anaemiaQ93730107
Genetic modifiers of sickle cell diseaseQ36035471
Sparing effect of hemoglobin F and hemoglobin A2 on the polymerization of hemoglobin S at physiologic ligand saturationsQ36333394
Indications and complications of splenectomy for children with sickle cell diseaseQ36652431
DNA polymorphisms at the BCL11A, HBS1L-MYB, and beta-globin loci associate with fetal hemoglobin levels and pain crises in sickle cell diseaseQ36800496
Lack of influence of fetal hemoglobin levels or erythrocyte indices on the severity of sickle cell anemiaQ37021584
Ten-year review of hospital admissions among children with sickle cell disease in KuwaitQ37236829
Sickle cell disease subphenotypes in patients from Southwestern Province of Saudi ArabiaQ37983011
Outcome of sickle cell anemia: a 4-decade observational study of 1056 patientsQ38471171
Alpha-thalassemia in blacks: genetic and clinical aspects and interactions with the sickle hemoglobin gene.Q39745092
Natural history of sickle cell anemia in Saudi Arabs. A study of 270 subjectsQ40108760
Clinical events in the first decade in a cohort of infants with sickle cell disease. Cooperative Study of Sickle Cell DiseaseQ40441624
Sickle cell disease as a cause of osteonecrosis of the femoral headQ44105081
A functional promoter polymorphism of the δ-globin gene is a specific marker of the Arab-Indian haplotypeQ44362006
Fetal hemoglobin in sickle cell anemia: Saudi patients from the Southwestern province have similar HBB haplotypes but higher HbF levels than African AmericansQ46327662
Silent brain infarcts in adult Kuwaiti sickle cell disease patientsQ48246104
Silent brain infarcts are rare in Kuwaiti children with sickle cell disease and high Hb F.Q48553801
Limitations of Hb F as a phenotypic modifier in sickle cell disease: study of Kuwaiti Arab patientsQ48840343
Patterns of mortality in adult sickle cell disease in the Al-Hasa region of Saudi ArabiaQ50075197
Hemoglobin F concentration as a function of age in Kuwaiti sickle cell disease patients.Q50692954
Splenectomy in patients with sickle-cell disease.Q51001209
The prevalence of sickle cell disease in Saudi children and adolescents. A community-based survey.Q51677474
Two different forms of homozygous sickle cell disease occur in Saudi ArabiaQ53857113
Distribution of Sickle-cell Hæmoglobin in Saudi ArabiaQ59020396
Acute chest syndrome in adult sickle cell disease in eastern Saudi Arabia.Q64891128
Fetal haemoglobin production and the sickle gene in the oases of Eastern Saudi ArabiaQ67447872
Pain in sickle cell disease. Rates and risk factorsQ67691472
Priapism associated with the sickle cell hemoglobinopathies: prevalence, natural history and sequelaeQ68175066
Effects of glucose-6-phosphate dehydrogenase deficiency upon sickle cell anemiaQ68273357
Leg Ulceration in Sickle Cell AnemiaQ69744791
Infections and sickle cell disease in Eastern Saudi Arabian childrenQ69946178
Cholelithiasis in patients with major sickle hemoglobinopathiesQ71253874
The acute chest syndrome in sickle cell disease: incidence and risk factors. The Cooperative Study of Sickle Cell DiseaseQ71632332
Variation in fetal hemoglobin parameters and predicted hemoglobin S polymerization in sickle cell children in the first two years of life: Parisian Prospective Study on Sickle Cell DiseaseQ71654523
Splenic function in Saudi children with sickle cell diseaseQ72379159
Splenic function in sickle cell disease in the Eastern Province of Saudi ArabiaQ72730698
Splenic function in sickle cell anemia patients in Qatif, Saudi ArabiaQ73341711
Avascular necrosis of the hip in children with sickle cell disease and high Hb F: magnetic resonance imaging findings and influence of alpha-thalassemia traitQ73843461
Avascular necrosis of the femoral head in adult Kuwaiti sickle cell disease patientsQ73944784
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectIndiaQ668
Saudi ArabiaQ851
phenotypeQ104053
sickle-cell diseaseQ185034
P304page(s)597-604
P577publication date2013-11-13
P1433published inBritish Journal of HaematologyQ4970200
P1476titleSickle cell disease in Saudi Arabia: the phenotype in adults with the Arab-Indian haplotype is not benign
P478volume164