Effects of combination lipid therapy in type 2 diabetes mellitus

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Effects of combination lipid therapy in type 2 diabetes mellitus is …
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scholarly articleQ13442814

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P356DOI10.1056/NEJMOA1001282
P932PMC publication ID2879499
P698PubMed publication ID20228404

P50authorJohn BuseQ6224073
Hertzel C. GersteinQ41696958
David C GoffQ96109271
Faramarz Ismail-BeigiQ98918532
ACCORD Study GroupQ98918533
Jeffrey L ProbstfieldQ114443555
Denise G Simons-MortonQ125329956
William T FriedewaldQ125330182
P2093author name stringHenry N Ginsberg
William C Cushman
Lawrence A Leiter
Richard H Grimm
J Thomas Bigger
John R Crouse
Marshall B Elam
Peter Linz
Robert P Byington
Laura C Lovato
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Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarctionQ29618673
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Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study GroupQ29619877
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Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart diseaseQ34687253
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Effect of fenofibrate-mediated increase in plasma homocysteine on the progression of coronary artery disease in type 2 diabetes mellitusQ44819058
Simvastatin does not have a clinically significant pharmacokinetic interaction with fenofibrate in humansQ45022898
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Impact of diabetes on mortality after the first myocardial infarction. The FINMONICA Myocardial Infarction Register Study Group.Q50897068
Evolution of the lipid trial protocol of the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial.Q51910741
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P433issue17
P407language of work or nameEnglishQ1860
P921main subjecttype 2 diabetesQ3025883
P304page(s)1563-1574
P577publication date2010-03-14
P1433published inThe New England Journal of MedicineQ582728
P1476titleEffects of combination lipid therapy in type 2 diabetes mellitus
P478volume362

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Q38434603Effect of switch to the highest dose of rosuvastatin versus add-on-statin fenofibrate versus add-on-statin nicotinic acid/laropiprant on oxidative stress markers in patients with mixed dyslipidemia.
Q28244205Effect on cardiovascular risk of high density lipoprotein targeted drug treatments niacin, fibrates, and CETP inhibitors: meta-analysis of randomised controlled trials including 117,411 patients
Q58127107Effects of Intensive Systolic Blood Pressure Lowering on Cardiovascular Events and Mortality in Patients With Type 2 Diabetes Mellitus on Standard Glycemic Control and in Those Without Diabetes Mellitus: Reconciling Results From ACCORD BP and SPRINT
Q64947749Effects of Non-statin Lipid-Modifying Agents on Cardiovascular Morbidity and Mortality Among Statin-Treated Patients: A Systematic Review and Network Meta-Analysis.
Q51565743Effects of antidiabetic drugs on the incidence of macrovascular complications and mortality in type 2 diabetes mellitus: a new perspective on sodium-glucose co-transporter 2 inhibitors.
Q34262967Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study
Q38293501Effects of established hypolipidemic drugs on HDL concentration, subclass distribution, and function
Q57274310Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study
Q45535226Effects of fibrates on cardiovascular outcomes
Q61873322Effects of fibrates on cardiovascular outcomes – Authors' reply
Q33576435Effects of fibrates on cardiovascular outcomes: a systematic review and meta-analysis.
Q34008161Effects of intensive blood-pressure control in type 2 diabetes mellitus
Q30840447Effects of intensive glycaemic control on ischaemic heart disease: analysis of data from the randomised, controlled ACCORD trial
Q35129072Effects of lipid-lowering drugs on high-density lipoprotein subclasses in healthy men-a randomized trial.
Q33620031Effects of medical therapies on retinopathy progression in type 2 diabetes
Q51371652Effects of multiple factorial intervention on ambulatory BP profile and renal function in hypertensive type 2 diabetic patients with overt nephropathy - a pilot study.
Q33855092Effects of niacin combination therapy with statin or bile acid resin on lipoproteins and cardiovascular disease
Q57591322Effects of non-statin antilipemic drugs on vascular endothelial function in patients with type 2 diabetes with hypercholesterolemia
Q35189566Effects of the dual peroxisome proliferator-activated receptor-α/γ agonist aleglitazar on renal function in patients with stage 3 chronic kidney disease and type 2 diabetes: a Phase IIb, randomized study
Q34206025Effects of the new dual PPAR α/δ agonist GFT505 on lipid and glucose homeostasis in abdominally obese patients with combined dyslipidemia or impaired glucose metabolism
Q52599940Efficacy and Safety of Pemafibrate Versus Fenofibrate in Patients with High Triglyceride and Low HDL Cholesterol Levels: A Multicenter, Placebo-Controlled, Double-Blind, Randomized Trial.
Q51744121Efficacy and safety of Zhibitai in combination with atorvastatin for lipid lowering in patients with coronary heart disease.
Q59652471Efficacy and safety of alirocumab, a fully human PCSK9 monoclonal antibody, in high cardiovascular risk patients with poorly controlled hypercholesterolemia on maximally tolerated doses of statins: rationale and design of the ODYSSEY COMBO I and II t
Q64114401Efficacy and safety of pemafibrate in people with type 2 diabetes and elevated triglyceride levels: 52-week data from the PROVIDE study
Q37436379Efficacy and tolerability of adding coenzyme A 400 U/d capsule to stable statin therapy for the treatment of patients with mixed dyslipidemia: an 8-week, multicenter, double-blind, randomized, placebo-controlled study
Q93377781Efficacy of negative pressure wound therapy using vacuum-assisted closure combined with photon therapy for management of diabetic foot ulcers
Q37074239Eicosapentaenoic Acid Inhibits Oxidation of ApoB-containing Lipoprotein Particles of Different Size In Vitro When Administered Alone or in Combination With Atorvastatin Active Metabolite Compared With Other Triglyceride-lowering Agents
Q55107177Elevated plasma lipoprotein(a) levels were associated with increased risk of cardiovascular events in Chinese patients with stable coronary artery disease.
Q90655312Emerging Mechanisms of Cardiovascular Protection for the Omega-3 Fatty Acid Eicosapentaenoic Acid
Q51334679Emerging approaches for the treatment of hypertriglyceridemia.
Q38263909Emerging drugs for hyperlipidaemia: an update
Q38075029Emerging drugs for managing kidney disease in patients with diabetes.
Q38613935Emerging innovative therapeutic approaches targeting PCSK9 to lower lipids
Q38217102Emerging therapeutic approaches to treat dyslipidemia
Q34335153Epidemiology, comparative effectiveness research, and the National Institutes of Health: forces for health
Q37288105Established and emerging approaches for the management of dyslipidaemia
Q64285261Evaluating All Potential Oral Complications of Diabetes Mellitus
Q24608464Evaluation and treatment of hypertriglyceridemia: an Endocrine Society clinical practice guideline
Q37812387Event reduction: revisiting why we treat with statins and harnessing current evidence towards optimal therapy
Q83749876Evidence-based medicine and the selection of lipid-lowering therapy in type 2 diabetes
Q84007797Evidence-based medicine should be practiced for primary prevention and secondary prevention of cardiovascular disease
Q47769899Evolving Role of Non-Statin Therapy for the Management of Dyslipidemia and Cardiovascular Risk Reduction: Past, Present, and Future.
Q34880292Evolving targets for lipid-modifying therapy
Q38074336Evolving therapeutic options for type 2 diabetes mellitus: an overview
Q38058381Examining the safety of PPAR agonists - current trends and future prospects
Q36087108Extended-Release Niacin Versus Fenofibrate in HIV-Infected Participants With Low High-Density Lipoprotein Cholesterol: Effects on Endothelial Function, Lipoproteins, and Inflammation
Q89850024Factors Associated with Poor Glycemic and Lipid Levels in Ambulatory Diabetes Mellitus Type 2 Patients in Asmara, Eritrea: A Cross-Sectional Study
Q36703114Facts and principles learned at the 39th Annual Williamsburg Conference on Heart Disease
Q44206732Favourable effects of fenofibrate on lipids and cardiovascular disease in women with type 2 diabetes: results from the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study.
Q46488015Façons d’identifier et de prendre en charge la dyslipidémie athérogène: Une conséquence métabolique de l’obésité et du diabète
Q35103583Fenofibrate administration does not affect muscle triglyceride concentration or insulin sensitivity in humans.
Q40777122Fenofibrate and extended-release niacin improve the endothelial protective effects of HDL in patients with metabolic syndrome.
Q37612824Fenofibrate and metabolic syndrome
Q38088377Fenofibrate and the kidney: an overview.
Q37681585Fenofibrate improves endothelial function and plasma myeloperoxidase in patients with type 2 diabetes mellitus: an open-label interventional study
Q37898699Fenofibrate plus simvastatin (fixed-dose combination) for the treatment of dyslipidaemia
Q101217453Fenofibrate prevents iron induced activation of canonical Wnt/β-catenin and oxidative stress signaling in the retina
Q42281309Fenofibrate reduces C-reactive protein levels in hypertriglyceridemic patients with high risks for cardiovascular diseases
Q30419020Fenofibrate-associated changes in renal function and relationship to clinical outcomes among individuals with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) experience
Q38118853Fenofibrate-associated nephrotoxicity: a review of current evidence
Q37653029Fenofibrate/simvastatin fixed-dose combination in the treatment of mixed dyslipidemia: safety, efficacy, and place in therapy
Q33933474Fenofibrate: a review of its lipid-modifying effects in dyslipidemia and its vascular effects in type 2 diabetes mellitus
Q95794110Fenofibrate: a review of its use in dyslipidaemia
Q37992119Fenofibric acid for hyperlipidemia
Q37771902Fibrate therapy in the management of diabetic dyslipidemia: there is no ACCORD to be found
Q94454408Fibrates Revisited: Potential Role in Cardiovascular Risk Reduction
Q42218338Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2.
Q38260501Fibrates and niacin: is there a place for them in clinical practice?
Q21246041Fibrates are an essential part of modern anti-dyslipidemic arsenal: spotlight on atherogenic dyslipidemia and residual risk reduction
Q84372846Fibrates consistently lower risk of cardiovascular events across high-risk groups
Q24203618Fibrates for primary prevention of cardiovascular disease events
Q30241199Fibrates for primary prevention of cardiovascular disease events.
Q24186376Fibrates for secondary prevention of cardiovascular disease and stroke
Q43050781Fibrates in CVD: a step towards personalised medicine
Q49571281Fibrates in the management of atherogenic dyslipidemia.
Q84960836Fibrates reduce the risk of major cardiovascular and coronary events compared with placebo, but do not affect risk of cardiovascular or all-cause mortality
Q34796255Fish oil and the pan-PPAR agonist tetradecylthioacetic acid affect the amino acid and carnitine metabolism in rats
Q86118649Fish oils, coronary heart disease, and the environment
Q37448634Four Statin Benefit Groups Defined by The 2013 ACC/AHA New Cholesterol Guideline are Characterized by Increased Plasma Level of Electronegative Low-Density Lipoprotein.
Q37030996Frail HDLs and stiff arteries in type 2 diabetes in juveniles
Q38200673Gamma-glutamyltransferase predicts increased risk of mortality: a systematic review and meta-analysis of prospective observational studies
Q57148091Genetic Tools for Coronary Risk Assessment in Type 2 Diabetes: A Cohort Study From the ACCORD Clinical Trial
Q44874088Genetic Variants in HSD17B3, SMAD3, and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes.
Q36573908Genetic determinants of cardiometabolic risk: a proposed model for phenotype association and interaction
Q36195926Glucose control and cardiovascular outcomes: reorienting approach
Q38736800Glucose targets for preventing diabetic kidney disease and its progression
Q61455627Glycemic and blood-pressure control—lower is not better
Q38720697Guidelines for Management of Hyperlipidemia: Implications for Treatment of Patients with Stroke Secondary to Atherosclerotic Disease.
Q37251490Guidelines for the primary prevention of stroke: a statement for healthcare professionals from the American Heart Association/American Stroke Association
Q93109141HDL Triglycerides: A New Marker of Metabolic and Cardiovascular Risk
Q34614842HDL and cognition in neurodegenerative disorders.
Q30251918HDL as a prognostic biomarker for coronary atherosclerosis: the role of inflammation
Q38739884HDL cholesterol: reappraisal of its clinical relevance
Q38195221HDL hypothesis: where do we stand now?
Q36918309HDL, Atherosclerosis, and Emerging Therapies
Q46866176HDL--is it too big to fail?
Q38087383HDL-C: clinical equipoise and vascular endothelial function
Q38214018HDL-targeted therapies: progress, failures and future
Q26782972HDL/ApoA-1 infusion and ApoA-1 gene therapy in atherosclerosis
Q38217089HDL: to treat or not to treat?
Q36691768Haptoglobin genotype and cardiovascular outcomes in diabetes mellitus - natural history of the disease and the effect of vitamin E treatment. Meta-analysis of the medical literature
Q34758108Health outcomes in diabetics measured with Minnesota Community Measurement quality metrics.
Q36425790High Human Cytomegalovirus IgG Level is Associated with Increased Incidence of Diabetic Atherosclerosis in Type 2 Diabetes Mellitus Patients
Q58130023High Triglycerides Are Associated With Increased Cardiovascular Events, Medical Costs, and Resource Use: A Real-World Administrative Claims Analysis of Statin-Treated Patients With High Residual Cardiovascular Risk
Q37043222High density lipoprotein and cardiovascular diseases.
Q26750603High density lipoprotein and metabolic disease: Potential benefits of restoring its functional properties
Q37264429High density lipoprotein: a therapeutic target in type 2 diabetes
Q83426043High doses of rosuvastatin are superior to low doses of rosuvastatin plus fenofibrate or n-3 fatty acids in mixed dyslipidemia
Q93026142High level of individual lipid profile and lipid ratio as a predictive marker of poor glycemic control in type-2 diabetes mellitus
Q38965138High-density Lipoprotein and Low-density Lipoprotein Therapeutic Approaches in Acute Coronary Syndromes.
Q36139932High-density lipoprotein cholesterol and particle concentrations, carotid atherosclerosis, and coronary events: MESA (multi-ethnic study of atherosclerosis).
Q33876182Hotline update of clinical trials and registries presented at the American College of Cardiology Congress 2010: ACCORD, INVEST, NAVIGATOR, RACE II, SORT OUT III, CSP-474, DOSE, ASPIRE and more
Q35738372How do elevated triglycerides and low HDL-cholesterol affect inflammation and atherothrombosis?
Q38824420How to assess and manage cardiovascular risk associated with lipid alterations beyond LDL.
Q36609968Hyperlipidemia as a risk factor for cardiovascular disease
Q37803231Hypertension 2010: what was new for the cardiologist?
Q37861888Hypertension and lipid management in prediabetic states
Q39181612Hypertriglyceridaemia and risk of coronary artery disease
Q92793323Hypertriglyceridaemia predicts subsequent long-term risk of cardiovascular events in Chinese adults: 23-year follow-up of the Daqing Diabetes Study
Q60533968Hypertriglyceridemia
Q49798045Hypertriglyceridemia - Common Causes, Prevention and treatment Strategies
Q35571714Hypertriglyceridemia Is Independently Associated with Renal, but Not Retinal Complications in Subjects with Type 2 Diabetes: A Cross-Sectional Analysis of the Renal Insufficiency And Cardiovascular Events (RIACE) Italian Multicenter Study
Q26750954Hypertriglyceridemia and Cardiovascular Diseases: Revisited
Q47180199Hypertriglyceridemia and atherosclerosis
Q88697605Hypertriglyceridemia and cardiovascular risk: a cautionary note about metabolic confounding
Q55176268Hypertriglyceridemia in Diabetes Mellitus: Implications for Pediatric Care.
Q34687470Hypertriglyceridemia: a too long unfairly neglected major cardiovascular risk factor
Q30244825Hypertriglyceridemia: the importance of identifying patients at risk
Q38108834Icosapent ethyl for the treatment of hypertriglyceridemia
Q33580249Impact of admission triglyceride for early outcome in diabetic patients with stable coronary artery disease
Q49221091Impact of high-density lipoprotein 3 cholesterol subfraction on periprocedural myocardial injury in patients who underwent elective percutaneous coronary intervention.
Q40740507Impact of lipid metabolism parameters on the development and progression of coronary artery disease : An update
Q64979817Impediments to clinical application of exercise interventions in the treatment of cardiometabolic disease.
Q33706621Importance of cardiovascular disease risk management in patients with type 2 diabetes mellitus
Q38393758Improving the odds: ezetimibe and cardiovascular disease
Q37577126In vivo actions of peroxisome proliferator-activated receptors: glycemic control, insulin sensitivity, and insulin secretion
Q35233119Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study
Q37236166Incorporating Concomitant Medications into Genome-Wide Analyses for the Study of Complex Disease and Drug Response
Q47844045Incorporation of PCSK9 inhibitors into prevention of atherosclerotic cardiovascular disease.
Q36721159Increased Rosuvastatin Dose versus Concomitant Fenofibrate and Rosuvastatin Therapy to Achieve Lipid Goal in Patients with Diabetes or Atherosclerosis with Metabolic Syndrome
Q38786058Inflammation and beyond: new directions and emerging drugs for treating atherosclerosis
Q93049588Inhibition of Angiopoietin-Like Protein 3 With a Monoclonal Antibody Reduces Triglycerides in Hypertriglyceridemia
Q35936964Inhibition of hepatic sulfatase-2 in vivo: a novel strategy to correct diabetic dyslipidemia.
Q38001736Inhibition of pro-protein convertase subtilisin kexin 9 [corrected] (PCSK-9) as a treatment for hyperlipidaemia
Q57688763Insulin and glucose-lowering agents for treating people with diabetes and chronic kidney disease
Q37636062Insulin-regulated protein palmitoylation impacts endothelial cell function.
Q38068591Intensive blood pressure control in obese diabetic patients: clinical relevance of stroke prevention in the ACCORD trial
Q34083400Intensive glycaemic control for patients with type 2 diabetes: systematic review with meta-analysis and trial sequential analysis of randomised clinical trials
Q26777184Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia
Q36302771Interaction between SNPs in the RXRA and near ANGPTL3 gene region inhibits apoB reduction after statin-fenofibric acid therapy in individuals with mixed dyslipidemia
Q36783920Introduction to the Third World Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension (CODHy): outcome studies versus clinical experience in the treatment of diabetes
Q37964753Is combination therapy an effective way of reaching lipid goals in type 2 diabetes mellitus?
Q30372692Is fenofibrate a reasonable treatment for diabetic microvascular disease?
Q36664118Is it time to screen for the haptoglobin genotype to assess the cardiovascular risk profile and vitamin E therapy responsiveness in patients with diabetes?
Q30397875Is prevention a fantasy, or the future of medicine? A panoramic view of recent data, status, and direction in cardiovascular prevention
Q36011273Is the ratio of apoB/apoA-1 the best predictor for the severity of coronary artery lesions in Chinese diabetics with stable angina pectoris? An assessment based on Gensini scores
Q35871962Is there a role for hypolipidaemic drug therapy in the prevention or treatment of microvascular complications of diabetes?
Q49245728J Curve in Hypertension.
Q58362346Japan Atherosclerosis Society (JAS) Guidelines for Prevention of Atherosclerotic Cardiovascular Diseases 2017
Q55069710Japanese Clinical Practice Guideline for Diabetes 2016.
Q38240747LDL cholesterol: controversies and future therapeutic directions
Q64355400LDL triglycerides, hepatic lipase activity, and coronary artery disease: An epidemiologic and Mendelian randomization study
Q38511045LDL, HDL, VLDL, and CVD Prevention: Lessons from Genetics?
Q46942263LDL-cholesterol versus non-HDL-to-HDL-cholesterol ratio and risk for coronary heart disease in type 2 diabetes.
Q35747811LPL gene variants affect apoC-III response to combination therapy of statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia
Q36721783Lack of Association between High-Density Lipoprotein Cholesterol and Angiographic Coronary Lesion Severity in Chinese Patients with Low Background Low-Density Lipoprotein Cholesterol
Q38110701Landmark lipid-lowering trials in the primary prevention of cardiovascular disease.
Q90079595Legacy effect of fibrate add-on therapy in diabetic patients with dyslipidemia: a secondary analysis of the ACCORDION study
Q91760069Leveraging Genetics to Improve Cardiovascular Health in Diabetes: The 2018 Edwin Bierman Award Lecture
Q92150307Life Style Intervention Improves Retinopathy Status-The Finnish Diabetes Prevention Study
Q36947413Lifestyle intervention and/or statins for the reduction of C-reactive protein in type 2 diabetes: from the look AHEAD study
Q33559274Limitations of real-world treatment with atorvastatin monotherapy for lowering LDL-C in high-risk cardiovascular patients in the US.
Q33567290Lipid Lowering Therapy to Modify Plaque Microstructures.
Q27024982Lipid abnormalities in kidney disease and management strategies
Q34419027Lipid control and use of lipid-regulating drugs for prevention of cardiovascular events in Chinese type 2 diabetic patients: a prospective cohort study
Q37853015Lipid control in patients with diabetes mellitus
Q37902579Lipid lowering therapy in type 2 diabetes
Q34530349Lipid management in the prevention of stroke: a meta-analysis of fibrates for stroke prevention
Q34131027Lipid regulation in lipodystrophy versus the obesity-associated metabolic syndrome: the dissociation of HDL-C and triglycerides
Q38589286Lipid-Lowering Drug Therapy for CVD Prevention: Looking into the Future
Q38118034Lipid-lowering agents
Q27024352Lipid-lowering agents in the management of nonalcoholic fatty liver disease
Q37859778Lipid-lowering effects of ezetimibe and simvastatin in combination
Q35232239Lipid-lowering therapy in older persons
Q26827432Lipid-lowering therapy: who can benefit?
Q47769390Lipid-modulating treatments for mixed dyslipidemia increase HDL-associated phospholipase A2 activity with differential effects on HDL subfractions
Q34734402Lipolysis, and not hepatic lipogenesis, is the primary modulator of triglyceride levels in streptozotocin-induced diabetic mice.
Q92990898Lipoprotein Lipase Inhibitor, Nordihydroguaiaretic Acid, Aggravates Metabolic Phenotypes and Alters HDL Particle Size in the Western Diet-Fed db/db Mice
Q58593985Long-Term Effects of Intensive Glycemic and Blood Pressure Control and Fenofibrate Use on Kidney Outcomes
Q33851861Long-term effects of intensive glucose lowering on cardiovascular outcomes
Q36472753Long-term effects of the Diabetes Prevention Program interventions on cardiovascular risk factors: a report from the DPP Outcomes Study
Q34757003Long-term efficacy of adding fenofibric acid to moderate-dose statin therapy in patients with persistent elevated triglycerides
Q88216068Long-term outcomes associated with triple-goal achievement in patients with type 2 diabetes mellitus (T2DM)
Q37170469Longitudinal Patterns of Blood Pressure, Incident Cardiovascular Events, and All-Cause Mortality in Normotensive Diabetic People
Q34154005Longitudinal changes in dietary fat intake and associated changes in cardiovascular risk factors in adults with type 2 diabetes: the ACCORD trial.
Q36892763Loss of PPARα perpetuates sex differences in stroke reflected by peripheral immune mechanisms
Q30408720Loss-of-function mutations in APOC3, triglycerides, and coronary disease
Q34731504Low HDL-C level is associated with the development of intracranial artery stenosis: analysis from the Chinese IntraCranial AtheroSclerosis (CICAS) study
Q35810903Low Plasma Hdl Cholesterol and Elevated C Reactive Protein further Increase Cardiovascular Disease Risk in Latinos with Type 2 Diabetes
Q35650429Low incidence of paradoxical reductions in HDL-C levels in dyslipidemic patients treated with fenofibrate alone or in combination with ezetimibe or ezetimibe/simvastatin
Q48327312Low triglyceride as a marker for increased risk of cardiovascular diseases in patients with long-term type 2 diabetes: A cross-sectional survey in China.
Q57796293Lower extremity arterial disease in patients with diabetes: a contemporary narrative review
Q33890208Lowering low-density lipoprotein cholesterol levels in patients with type 2 diabetes mellitus
Q35230819Lowering triglycerides to modify cardiovascular risk: will icosapent deliver?
Q50099270Magnolol-mediated regulation of plasma triglyceride through affecting lipoprotein lipase activity in apolipoprotein A5 knock-in mice.
Q55464963Management of Dyslipidemia in Type 2 Diabetes: Recent Advances in Nonstatin Treatment.
Q30249076Management of Lipid Levels and Cardiovascular Disease in HIV-Infected Individuals: Just Give Them a Statin?
Q37689636Management of cardiovascular disease risk factors in older adults with type 2 diabetes mellitus: 2002-2012 literature review
Q64262692Management of diabetic dyslipidemia: An update
Q38039980Management of dyslipidemias in the presence of the metabolic syndrome or type 2 diabetes.
Q34068746Management of dyslipidemias with fibrates, alone and in combination with statins: role of delayed-release fenofibric acid.
Q33935729Management of hypertriglyceridemia in the diabetic patient
Q34509936Management of low levels of high-density lipoprotein-cholesterol
Q38106502Management of the patient with diabetes and coronary artery disease: a contemporary review
Q37102861Management of type 2 diabetes: evolving strategies for the treatment of patients with type 2 diabetes
Q50179675Managing Diabetes and Cardiovascular Risk in Chronic Kidney Disease Patients.
Q37965730Mapping body fat distribution: a key step towards the identification of the vulnerable patient?
Q33643266Mass spectrometric immunoassay and MRM as targeted MS-based quantitative approaches in biomarker development: potential applications to cardiovascular disease and diabetes
Q38079914Medical management and strategies to prevent coronary artery disease in patients with type 2 diabetes mellitus.
Q33855386Medical management of diabetic retinopathy: fenofibrate and ACCORD Eye studies
Q38083007Medical management of stable coronary atherosclerosis.
Q37875489Medical treatment in acute and long-term secondary prevention after transient ischaemic attack and ischaemic stroke
Q48231572Mendelian randomisation study of the associations of vitamin B12 and folate genetic risk scores with blood pressure and fasting serum lipid levels in three Danish population-based studies.
Q84187504Mendelian randomisation, triglycerides, and CHD
Q37901053Metabolic syndrome: nature, therapeutic solutions and options
Q64083675Metformin in patients with and without diabetes: a paradigm shift in cardiovascular disease management
Q26829098Modulating peroxisome proliferator-activated receptors for therapeutic benefit? Biology, clinical experience, and future prospects
Q34594935Molecular Implications of the PPARs in the Diabetic Eye.
Q34099937Molecular mechanisms of vascular dysfunction and cardiovascular biomarkers in type 2 diabetes.
Q37254899Molecular sources of residual cardiovascular risk, clinical signals, and innovative solutions: relationship with subclinical disease, undertreatment, and poor adherence: implications of new evidence upon optimizing cardiovascular patient outcomes
Q38843479Monoclonal Antibodies for Lipid Management
Q52673953Myeloperoxidase mediated HDL oxidation and HDL proteome changes do not contribute to dysfunctional HDL in Chinese subjects with coronary artery disease.
Q51245259N-3 polyunsaturated fatty acids improve lipoprotein particle size and concentration in Japanese patients with type 2 diabetes and hypertriglyceridemia: a pilot study.
Q34230175Nanopharmaceuticals (part 1): products on the market
Q37780943National Kidney Foundation consensus conference on cardiovascular and kidney diseases and diabetes risk: an integrated therapeutic approach to reduce events
Q47649557National Trends in Nonstatin Use and Expenditures Among the US Adult Population From 2002 to 2013: Insights From Medical Expenditure Panel Survey
Q34475442Near-Normalization of Glucose and Microvascular Diabetes Complications: Data from ACCORD and ADVANCE.
Q28072298New Era of Lipid-Lowering Drugs
Q53401128New Fixed-Dose Combinations of Fenofibrate/Simvastatin Therapy Significantly Improve the Lipid Profile of High-Risk Patients with Mixed Dyslipidemia Versus Monotherapies.
Q61449080New Insights into Mechanisms of Action for Omega-3 Fatty Acids in Atherothrombotic Cardiovascular Disease
Q53622322New Metrics for Economic Evaluation in the Presence of Heterogeneity: Focusing on Evaluating Policy Alternatives Rather than Treatment Alternatives.
Q90380337New Perspectives on Atherogenic Dyslipidaemia and Cardiovascular Disease
Q37899907New approaches to the treatment of nephropathy in diabetes
Q37956122New horizons for cholesterol ester transfer protein inhibitors
Q37984782New lipid-lowering drugs: an update
Q26863369New therapeutic principles in dyslipidaemia: focus on LDL and Lp(a) lowering drugs
Q47279052New treatment options for lipid-lowering therapy in subjects with type 2 diabetes.
Q44004071Niacin: the only vitamin that reduces cardiovascular events
Q36820609Nine-Year Effects of 3.7 Years of Intensive Glycemic Control on Cardiovascular Outcomes
Q36329934No accord for the ACCORD-Lipid trial results
Q37078453No effect of switching to high-dose rosuvastatin, add-on nicotinic acid, or add-on fenofibrate on serum vitamin D levels in patients with mixed dyslipidemia
Q39383777Non-HDL cholesterol vs. apo B for risk of coronary heart disease in healthy individuals: the EPIC-Norfolk prospective population study
Q37992604Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor?
Q50046562Non-fasting triglyceride levels in the Korean population with and without ischemic heart disease and cerebrovascular disease.
Q33901914Non-invited review: prevention of microvascular diabetic complications by fenofibrate: lessons from FIELD and ACCORD.
Q38074898Nonalcoholic fatty liver disease: current issues and novel treatment approaches
Q100946503Nonalcoholic steatohepatitis: the role of peroxisome proliferator-activated receptors
Q28084156Nonstatin Low-Density Lipoprotein-Lowering Therapy and Cardiovascular Risk Reduction-Statement From ATVB Council
Q34423344Nontraditional serum lipid variables and recurrent stroke risk
Q96129205Novel Insights into the Pathogenesis and Management of the Metabolic Syndrome
Q38265818Novel effective drugs for diabetic kidney disease? or not?
Q64262724Novel pharmacological therapy in type 2 diabetes mellitus with established cardiovascular disease: Current evidence
Q38074335Novel strategies for managing dyslipidemia: treatment beyond statins
Q26823249Novel therapies focused on the high-density lipoprotein particle
Q39175937Nutrient-sensing nuclear receptors PPARα and FXR control liver energy balance.
Q38186327Obesity, metabolic syndrome and diabetes mellitus after renal transplantation: prevention and treatment
Q30249819Obesity-related glomerulopathy: clinical and pathologic characteristics and pathogenesis.
Q34877739Observational study of effects of Saroglitazar on glycaemic and lipid parameters on Indian patients with type 2 diabetes
Q92339310Obstacles aux interventions cliniques liées à l’activité physique dans le traitement des maladies cardiométaboliques
Q28076399Omega-3 carboxylic acids monotherapy and combination with statins in the management of dyslipidemia
Q38477187One-year efficacy and safety of rosuvastatin + fenofibric acid combination therapy in patients with mixed dyslipidemia: evaluation of dose response
Q38283386Ongoing challenges for pharmacotherapy for dyslipidemia
Q24626884Opening a new lipid "apo-thecary": incorporating apolipoproteins as potential risk factors and treatment targets to reduce cardiovascular risk
Q84776096Optimal blood pressure for a patient with type 2 diabetes mellitus: insight from the ACCORD study
Q53168850Optimizing lipid-lowering therapy in the prevention of coronary heart disease.
Q26824004Origin and therapy for hypertriglyceridaemia in type 2 diabetes
Q40629785Orthostatic Hypotension in the ACCORD (Action to Control Cardiovascular Risk in Diabetes) Blood Pressure Trial: Prevalence, Incidence, and Prognostic Significance
Q33646630Outcomes of combined cardiovascular risk factor management strategies in type 2 diabetes: the ACCORD randomized trial
Q37909519Overcoming obstacles in risk factor management in type 2 diabetes mellitus
Q37419411Overview of omega-3 Fatty Acid therapies
Q42858697PCSK9 Inhibition: Does Lipoprotein Size Matter?
Q89207225PCSK9 Inhibitors in Lipid Management of Patients With Diabetes Mellitus and High Cardiovascular Risk: A Review
Q55332945PCSK9 Inhibitors: An Emerging Class of Medications.
Q41822823PCSK9 as a therapeutic target for cardiovascular disease
Q26784482PCSK9 inhibition: the way forward in the treatment of dyslipidemia
Q37996437PPAR agonists for the treatment of cardiovascular disease in patients with diabetes
Q36360452PPAR-α Agonist Fenofibrate Decreased Serum Irisin Levels in Type 2 Diabetes Patients with Hypertriglyceridemia
Q39200940PPAR-α agonists are still on the rise: an update on clinical and experimental findings
Q92128876PPARs as Nuclear Receptors for Nutrient and Energy Metabolism
Q37790384PPARs as therapeutic targets in cardiovascular disease
Q39145017PPARs in the central nervous system: roles in neurodegeneration and neuroinflammation.
Q26771753PPARs: Protectors or Opponents of Myocardial Function?
Q38038289PPARα as a therapeutic target in inflammation-associated diseases
Q35247278PURLs: Add a fibrate to a statin?
Q48923906Paradox of using intensive lowering of blood glucose in diabetics and strategies to overcome it and decrease cardiovascular risks.
Q33776208Paradoxical negative HDL cholesterol response to atorvastatin and simvastatin treatment in Chinese type 2 diabetic patients
Q37192024Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction
Q38757894Pathophysiology and treatment of atherosclerosis : Current view and future perspective on lipoprotein modification treatment
Q35689882Patient and physician factors influence decision-making in hypercholesterolemia: a questionnaire-based survey
Q36197709Patient considerations and clinical impact of cholesteryl ester transfer protein inhibitors in the management of dyslipidemia: focus on anacetrapib
Q92892621Pemafibrate, a New Selective PPARα Modulator: Drug Concept and Its Clinical Applications for Dyslipidemia and Metabolic Diseases
Q36366326Peroxisome Proliferator-Activated Receptor-α Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia
Q36261125Peroxisome Proliferator-Activated Receptors and the Heart: Lessons from the Past and Future Directions
Q37992593Peroxisome proliferator-activated receptor (PPAR α/γ) agonists as a potential target to reduce cardiovascular risk in diabetes
Q26866784Peroxisome proliferator-activated receptors and their ligands: nutritional and clinical implications--a review
Q37025572Persistent Effects of Intensive Glycemic Control on Retinopathy in Type 2 Diabetes in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Follow-On Study
Q38473168Persistent lipid abnormalities in statin-treated patients with diabetes mellitus in Europe and Canada: results of the Dyslipidaemia International Study
Q37142852Personalized vascular medicine: individualizing drug therapy
Q38203774Pharmacogenomics, lipid disorders, and treatment options
Q34628781Pharmacokinetics, efficacy and safety of aleglitazar for the treatment of type 2 diabetes with high cardiovascular risk
Q39320400Pharmacologic Treatment of Dyslipidemia in Diabetes: A Case for Therapies in Addition to Statins
Q38072617Pharmacologic interactions of multidrug therapy for dyslipidemia
Q37973129Pharmacologic prevention of microvascular and macrovascular complications in diabetes mellitus: implications of the results of recent clinical trials in type 2 diabetes
Q39015072Pharmacological management of diabetic dyslipidemia
Q37842120Pharmacological strategies for lowering LDL cholesterol: statins and beyond
Q38130111Pharmacotherapies for lipid modification: beyond the statins
Q37801374Pharmacotherapy of dyslipidemias in the adult population
Q84764505Pharmacotherapy: ACCORD Blood Pressure and ACCORD Lipid: how low can we go?
Q84639364Pharmacotherapy: Implications of high-dose statin link with incident diabetes
Q39908570Pleiotropic effects of fenofibrate therapy on rats with hypertriglycemia
Q37549374PoLA/CFPiP/PCS Guidelines for the Management of Dyslipidaemias for Family Physicians 2016.
Q37287426Polyunsaturated fatty acyl-coenzyme As are inhibitors of cholesterol biosynthesis in zebrafish and mice.
Q28076119Post-transplant dyslipidemia: Mechanisms, diagnosis and management
Q38460480Postprandial Dysmetabolism and Oxidative Stress in Type 2 Diabetes: Pathogenetic Mechanisms and Therapeutic Strategies
Q37639159Postprandial Hyperlipidemia and Remnant Lipoproteins
Q39440767Practical Considerations for the Use of Subcutaneous Treatment in the Management of Dyslipidaemia
Q47875819Practical aspects in the management of statin-associated muscle symptoms (SAMS).
Q38014975Pravastatin and fenofibrate in combination (Pravafenix(®)) for the treatment of high-risk patients with mixed hyperlipidemia
Q92399114Prediction of Proliferative Diabetic Retinopathy to Asymptomatic Obstructive Coronary Artery Disease in Chinese Type 2 Diabetes Individuals: An Exploratory Study
Q43718248Prevalence of dyslipidemia and goal attainment after initiating lipid-modifying therapy: a Thai multicenter study
Q37027567Prevalence of mixed dyslipidemia among Australian patients undergoing lipid-modifying therapy
Q55154739Prevention and management of statin adverse effects: A practical approach for pharmacists.
Q40087045Primary Prevention of Cardiovascular Disease in Diabetes Mellitus
Q38295069Primary prevention of atherosclerotic cardiovascular disease: controversies and clinical considerations
Q33972551Primary prevention of coronary heart disease: integration of new data, evolving views, revised goals, and role of rosuvastatin in management. A comprehensive survey
Q35622601Primary prevention with lipid lowering drugs and long term risk of vascular events in older people: population based cohort study
Q50870845Proceedings of the Christiana Care Health System Value Institute Value Symposium.
Q29619982Progress and challenges in translating the biology of atherosclerosis
Q38839105Progress in the care of common inherited atherogenic disorders of apolipoprotein B metabolism.
Q36138368Proof of concept in cardiovascular risk: the paradoxical findings in blood pressure and lipid abnormalities
Q37135042Quantification of concordance and discordance between apolipoprotein-B and the currently recommended non-HDL-cholesterol goals for cardiovascular risk assessment in patients with diabetes and hypertriglyceridemia
Q39988795RAS blockade for every diabetic patient: pro and con.
Q98174765Randomized Trials Versus Common Sense and Clinical Observation: JACC Review Topic of the Week
Q33833360Rare LPL gene variants attenuate triglyceride reduction and HDL cholesterol increase in response to fenofibric acid therapy in individuals with mixed dyslipidemia
Q33578422Rationale and design of REDUCE-IT: Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial
Q37466366Rationale and design of the Cardiovascular Inflammation Reduction Trial: a test of the inflammatory hypothesis of atherothrombosis
Q48131156Recent Insights into Pharmacologic Cardiovascular Risk Reduction in Type 2 Diabetes Mellitus
Q34343533Recent advances in preventing cardiovascular disorders by managing lipid levels
Q37892300Recent advances in the treatment of atherogenic dyslipidemia in type 2 diabetes mellitus
Q36443768Reducing vascular events risk in patients with dyslipidaemia: an update for clinicians
Q93609057References
Q93609219References
Q38160494Refocusing Peroxisome Proliferator Activated Receptor-α: A New Insight for Therapeutic Roles in Diabetes
Q64914760Relationship between CETP gene polymorphisms with coronary artery disease in Polish population.
Q35088129Relationship of high-density lipoprotein cholesterol with periprocedural myocardial injury following elective percutaneous coronary intervention in patients with low-density lipoprotein cholesterol below 70 mg/dL.
Q37390626Relationship of lipoproteins to cardiovascular events: the AIM-HIGH Trial (Atherothrombosis Intervention in Metabolic Syndrome With Low HDL/High Triglycerides and Impact on Global Health Outcomes).
Q36351005Relationships between components of metabolic syndrome and coronary intravascular ultrasound atherosclerosis measures in women without obstructive coronary artery disease: the NHLBI-Sponsored Women's Ischemia Syndrome Evaluation Study
Q43990488Repeat measurements of glycated haemoglobin A(1c) and N-terminal pro-B-type natriuretic peptide: divergent behaviour in diabetes mellitus
Q36968971Residual cardiovascular risk despite optimal LDL cholesterol reduction with statins: the evidence, etiology, and therapeutic challenges
Q82085286Residual cardiovascular risk in secondary prevention
Q26996039Residual macrovascular risk in 2013: what have we learned?
Q30419512Reversibility of fenofibrate therapy-induced renal function impairment in ACCORD type 2 diabetic participants
Q38239205Revising the high-density lipoprotein targeting strategies - insights from human and preclinical studies
Q38430793Role for combination therapy in diabetic dyslipidemia
Q38221965Role of HDL in those with diabetes
Q29994487Role of Non-Statins, LDL-C Thresholds, and Special Population Considerations: A Look at the Updated 2016 ACC Consensus Committee Recommendations
Q38546383Role of Peroxisome Proliferator-Activated Receptor α in Diabetic Nephropathy
Q37811855Role of fibrates in cardiovascular disease prevention, the ACCORD-Lipid perspective
Q27000731Role of lipotoxicity in endothelial dysfunction
Q37973966Role of the PPAR-α agonist fenofibrate in severe pediatric burn
Q93120785Rounding the corner on residual risk: Implications of REDUCE-IT for omega-3 polyunsaturated fatty acids treatment in secondary prevention of atherosclerotic cardiovascular disease
Q41753267Safety and efficacy of fibrate-statin combination therapy compared to fibrate monotherapy in patients with dyslipidemia: a meta-analysis
Q34481529Safety and efficacy of long-term combination therapy with bezafibrate and ezetimibe in patients with dyslipidemia in the prospective, observational J-COMPATIBLE study
Q38541832Safety considerations with fenofibrate/simvastatin combination.
Q42637141Safety of a fixed-dose combination of fenofibrate/pravastatin 160 mg/40 mg in patients with mixed hyperlipidaemia: a pooled analysis from a database of clinical trials
Q37854747Safety review of combination drugs for hyperlipidemia
Q38352759Saroglitazar for the treatment of dyslipidemia in diabetic patients
Q35492306Saroglitazar for the treatment of hypertrig-lyceridemia in patients with type 2 diabetes: current evidence
Q37882225Screening for type 2 diabetes and dysglycemia
Q34237385Secular trends in treatment and control of type 2 diabetes in an American Indian population: a 30-year longitudinal study
Q38110581Selective peroxisome proliferator-activated receptor α modulators (SPPARMα): the next generation of peroxisome proliferator-activated receptor α-agonists
Q59797390Serum Triglycerides and Atherosclerotic Cardiovascular Disease: Insights from Clinical and Genetic Studies
Q91875427Serum lipid management in patients with type 1 and type 2 diabetes: a hospital-based cohort study
Q36469056Serum lipid profile of newly diagnosed hypertensive patients in nnewi, South-East Nigeria
Q34286013Severe hypoglycemia symptoms, antecedent behaviors, immediate consequences and association with glycemia medication usage: Secondary analysis of the ACCORD clinical trial data
Q42931999Should glucose-sparing prescriptions be expected to reduce the cardiovascular risk of peritoneal dialysis patients?
Q42945058Should the treatment of diabetic dyslipidemia be modified after the Action to Control Cardiovascular Risk in Diabetes Lipid study?
Q37346390Should we start all patients with diabetic retinopathy on fenofibrates?
Q33406100Simvastatin and amlodipine induced thrombocytopenia in the same patient: double trouble and a literature review
Q89537341Spotlight on Icosapent Ethyl for Cardiovascular Risk Reduction: Evidence to Date
Q37412792Standards of care for type 2 diabetes in China.
Q34425055Standards of medical care in diabetes--2011.
Q24632533Standards of medical care in diabetes--2012
Q29620309Standards of medical care in diabetes--2013
Q38881156Statin combination therapy and cardiovascular risk reduction
Q48145497Statin drug interactions and related adverse reactions: an update
Q37700224Statin use and all-cause and cancer mortality: BioBank Japan cohort
Q28074144Statin-Associated Muscle Adverse Events: Update for clinicians
Q28083004Statin-associated muscle symptoms: impact on statin therapy-European Atherosclerosis Society Consensus Panel Statement on Assessment, Aetiology and Management
Q38020453Statins and beyond: concurrent strategies for prevention of cardiovascular disease in patients with type 2 diabetes
Q27010638Statins in cardiometabolic disease: what makes pitavastatin different?
Q36950782Strategies for improving cardiovascular health in women with diabetes mellitus: a review of the evidence
Q52599996Structure-guided evolution of a 2-phenyl-4-carboxyquinoline chemotype into PPARα selective agonists: New leads for oculovascular conditions.
Q36124203Study design, rationale, and baseline characteristics: evaluation of fenofibric acid on carotid intima-media thickness in patients with type IIb dyslipidemia with residual risk in addition to atorvastatin therapy (FIRST) trial
Q30454904Sub-optimal achievement of guideline-derived lipid goals in management of diabetes patients with atherosclerotic cardiovascular disease, despite high use of evidence-based therapies
Q38160901Summarizing the FIELD study: lessons from a 'negative' trial
Q89685776Supporting care for suboptimally controlled type 2 diabetes mellitus in general practice with a clinical decision support system: a mixed methods pilot cluster randomised trial
Q36602779Surprises From Genetic Analyses of Lipid Risk Factors for Atherosclerosis
Q36712679Switching statin-treated patients from fenofibrate to the prescription omega-3 therapy icosapent ethyl: a retrospective case series
Q36746311Systematic review and meta-analysis of 16 randomized clinical trials of radix astragali and its prescriptions for diabetic retinopathy
Q36745091Targeted Proteomics Identifies Paraoxonase/Arylesterase 1 (PON1) and Apolipoprotein Cs as Potential Risk Factors for Hypoalphalipoproteinemia in Diabetic Subjects Treated with Fenofibrate and Rosiglitazone
Q38904497Targeting ApoC-III to Reduce Coronary Disease Risk
Q38431166Targeting high-density lipoproteins: increasing de novo production versus decreasing clearance
Q38553529Targeting inflammation in metabolic syndrome.
Q24186667Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus
Q24202505Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus
Q24236456Targeting intensive glycaemic control versus targeting conventional glycaemic control for type 2 diabetes mellitus
Q41725917The 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular disease risk: a new paradigm supported by more evidence
Q42418260The 2013 American College of Cardiology (ACC)/American Heart Association (AHA) guidelines for cholesterol management and for cardiovascular risk stratification: a reappraisal
Q36783686The ACCORD (Action to Control Cardiovascular Risk in Diabetes) Lipid trial: what we learn from subgroup analyses
Q35871965The ACCORD-Lipid study: implications for treatment of dyslipidemia in Type 2 diabetes mellitus
Q92333057The Diagnosis and Treatment of Hypertriglyceridemia
Q30662013The Effect of Lipid Modification on Peripheral Artery Disease after Endovascular Intervention Trial (ELIMIT)
Q94237982The Effect of Pharmacy-Led, Small-Group Academic Detailing on Prescribing Patterns in an Ambulatory Care Clinic
Q57475802The Forgotten Lipids: Triglycerides, Remnant Cholesterol, and Atherosclerotic Cardiovascular Disease Risk
Q64923599The Microvascular and Macrovascular Benefits of Fibrates in Diabetes and the Metabolic Syndrome: A review.
Q41884591The Proatherogenic Effect of Chronic Nitric Oxide Synthesis Inhibition in ApoE-Null Mice Is Dependent on the Presence of PPAR α.
Q89534430The Rise and Fall "ing" of the HDL Hypothesis
Q28550746The Role of Metformin Response in Lipid Metabolism in Patients with Recent-Onset Type 2 Diabetes: HbA1c Level as a Criterion for Designating Patients as Responders or Nonresponders to Metformin
Q34106233The Role of PPARα Activation in Liver and Muscle
Q52722809The Role of Peroxisome Proliferator-Activated Receptor γ Coactivator 1α (PGC-1α) in Kidney Disease.
Q36882866The Treatment of Disorders of Lipid Metabolism
Q36517644The atherogenic dyslipidemia ratio [log(TG)/HDL-C] is associated with residual vascular risk, beta-cell function loss and microangiopathy in type 2 diabetes females
Q42773416The causes and consequences of low levels of high density lipoproteins in patients with diabetes
Q38246002The clinical burden of type 2 diabetes in patients with acute coronary syndromes: prognosis and implications for short- and long-term management
Q35332645The effect of bezafibrate and omega-3 fatty acids on lymphocyte cytokine release and systemic inflammation in patients with isolated hypertriglyceridemia
Q46962775The effect of fenofibrate on lymphocyte release of proinflammatory cytokines and systemic inflammation in simvastatin-treated patients with atherosclerosis and early glucose metabolism disturbances.
Q34615937The effects of medical management on the progression of diabetic retinopathy in persons with type 2 diabetes: the Action to Control Cardiovascular Risk in Diabetes (ACCORD) Eye Study
Q37978209The emerging role of HDL in glucose metabolism
Q28072835The emerging role of apolipoprotein C-III: beyond effects on triglyceride metabolism
Q37947160The epidemiological concept of residual risk
Q36047244The evolution of domain arrangements in proteins and interaction networks
Q38072612The evolution or revolution of statin therapy in primary prevention: where do we go from here?
Q34042836The fibrate gemfibrozil is a NO- and haem-independent activator of soluble guanylyl cyclase: in vitro studies
Q30393989The glucose triad and its role in comprehensive glycaemic control: current status, future management
Q37363449The influence of statin-fibrate combination therapy on lipids profile and apolipoprotein A5 in patients with acute coronary syndrome
Q38118163The need for combination drug therapies in patients with complex dyslipidemia
Q38267131The new cholesterol treatment guidelines from the American College of Cardiology/American Heart Association, 2013: what clinicians need to know
Q30357715The nuances of atherogenic dyslipidemia in diabetes: focus on triglycerides and current management strategies.
Q38273378The peroxisome proliferator-activated receptors in cardiovascular diseases: experimental benefits and clinical challenges.
Q35896110The receptor for advanced glycation end products and risk of peripheral arterial disease, amputation or death in type 2 diabetes: a population-based cohort study
Q38005926The relationship between lung inflammation and cardiovascular disease
Q37997004The renoprotective actions of peroxisome proliferator-activated receptors agonists in diabetes
Q37425564The reversal of cardiology practices: interventions that were tried in vain
Q38083006The role of early LDL lowering to prevent the onset of atherosclerotic disease
Q35060328The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol Rationale and study design. The Athe
Q35060314The role of niacin in raising high-density lipoprotein cholesterol to reduce cardiovascular events in patients with atherosclerotic cardiovascular disease and optimally treated low-density lipoprotein cholesterol: baseline characteristics of study p
Q33776214The role of triglyceride in cardiovascular disease in asian patients with type 2 diabetes--a systematic review.
Q35602424The role of triglycerides in atherosclerosis
Q92522639The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction
Q61445463The triglyceride paradox in the mortality of coronary artery disease
Q50193445The year in cardiology 2017: prevention.
Q35078274Therapeutic Effects of PPAR α on Neuronal Death and Microvascular Impairment
Q42372998Therapeutic Effects of PPARα Agonist on Ocular Neovascularization in Models Recapitulating Neovascular Age-Related Macular Degeneration
Q38596398Therapeutic Potential and Critical Analysis of the PCSK9 Monoclonal Antibodies Evolocumab and Alirocumab
Q38209811Therapeutic approaches to diabetic nephropathy--beyond the RAS.
Q37902643Therapeutic potential of copper chelation with triethylenetetramine in managing diabetes mellitus and Alzheimer's disease
Q37981725Therapeutic strategies to deplete macrophages in atherosclerotic plaques
Q37825945Therapies for diabetic dyslipidaemia
Q46108030Therapy with Astragalus polysaccharides rescues lipotoxic cardiomyopathy in MHC-PPARα mice
Q37964515Tight blood pressure control in diabetes: evidence-based review of treatment targets in patients with diabetes
Q57112903Towards more specific treatment for diabetic dyslipidemia
Q33585474Treating diabetic dyslipidemia: What have we learnt from recent clinical trials?
Q38201721Treating low high-density lipoprotein cholesterol: what is the evidence?
Q49689988Treatment of Dyslipidemia in Diabetes: Recent Advances and Remaining Questions.
Q33887783Treatment of Dyslipidemias to Prevent Cardiovascular Disease in Patients with Type 2 Diabetes
Q27026114Treatment of dyslipidemia
Q34499472Treatment of dyslipidemia in patients with type 2 diabetes
Q37923978Treatment of lipid disorders in obesity
Q39556962Treatment targets in the management of dyslipidemias: which targets in whom?
Q34546861Trends in diabetes medication use and prevalence of geriatric syndromes in older Mexican Americans from 1993/1994 to 2004/2005
Q92649743Trials in "True" Dyslipidemic Patients Are Urged to Reconsider Comprehensive Lipid Management as a Means to Reduce Residual Cardiovascular Risk
Q38932760Triglyceride Treatment in the Age of Cholesterol Reduction
Q40364483Triglyceride and HDL-C Dyslipidemia and Risks of Coronary Heart Disease and Ischemic Stroke by Glycemic Dysregulation Status: The Strong Heart Study
Q37015549Triglyceride and cardiovascular risk: A critical appraisal
Q89846775Triglyceride concentrations and non-high-density lipoprotein cholesterol goal attainment in the ODYSSEY phase 3 trials with alirocumab
Q36151033Triglyceride to high-density lipoprotein cholesterol ratio predicts cardiovascular outcomes in prevalent dialysis patients.
Q58550770Triglyceride-Rich Lipoproteins and Novel Targets for Anti-atherosclerotic Therapy
Q34181381Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
Q26745946Triglyceride-rich lipoproteins as a causal factor for cardiovascular disease
Q38240749Triglycerides and cardiovascular disease
Q91926577Triglycerides: Emerging Targets in Diabetes Care? Review of Moderate Hypertriglyceridemia in Diabetes
Q41104057Two Decades of Cardiovascular Trials With Primary Surrogate Endpoints: 1990-2011.
Q37033898Type 1 Deiodinase Regulates ApoA-I Gene Expression and ApoA-I Synthesis Independent of Thyroid Hormone Signaling
Q34023548Type 2 diabetes and cardiovascular disease: Have all risk factors the same strength?
Q37832118Type 2 diabetes mellitus in 2010: individualizing treatment targets in diabetes care
Q43491912Update dyslipidemia
Q37980739Update of the past year: a review from IDSA 2011.
Q26798326Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association
Q27687851Update on Prevention of Cardiovascular Disease in Adults With Type 2 Diabetes Mellitus in Light of Recent Evidence: A Scientific Statement From the American Heart Association and the American Diabetes Association.
Q33887918Update on lipids and C-reactive protein in acute and chronic coronary heart disease
Q45359231Update: clinical lipidology
Q34961885Updated guidelines for the management of dyslipidemia and prevention of cardiovascular disease by pharmacists.
Q36134940Use of Lipid-Lowering Medications and the Likelihood of Achieving Optimal LDL-Cholesterol Goals in Coronary Artery Disease Patients
Q90338365Use of fenofibrate on cardiovascular outcomes in statin users with metabolic syndrome: propensity matched cohort study
Q34428524Use of fibrates and cancer risk: a systematic review and meta-analysis of 17 long-term randomized placebo-controlled trials
Q35903762Use of fibrates in the United States and Canada
Q26765234Use of fibrates in the metabolic syndrome: A review
Q97682129Use of non-LDL-C lipid-lowering medications in patients with type 2 diabetes
Q89312828Using Genetic Variants in the Targets of Lipid Lowering Therapies to Inform Drug Discovery and Development: Current and Future Treatment Options
Q64337067Utilization and adherence to guideline-recommended lipid-lowering therapy at an academic medical center
Q47263832Validation of Risk Equations for Complications of Type 2 Diabetes (RECODe) Using Individual Participant Data From Diverse Longitudinal Cohorts in the U.S.
Q34135420Varespladib methyl in cardiovascular disease
Q57269550Variants in the APOA5 gene region and the response to combination therapy with statins and fenofibric acid in a randomized clinical trial of individuals with mixed dyslipidemia
Q36082525Visual assessment of the similarity between a patient and trial population: Is This Clinical Trial Applicable to My Patient?
Q39388920We Know More Than We Can Tell About Diabetes and Vascular Disease: The 2016 Edwin Bierman Award Lecture
Q38931845What Are We Learning from the FDA-Mandated Cardiovascular Outcome Studies for New Pharmacological Antidiabetic Agents?
Q37812296What combination therapy with a statin, if any, would you recommend?
Q82085276What intervention trials don't tell us: the residual risk in primary prevention
Q39528844What should we do about Hypertriglyceridemia in Coronary Artery Disease Patients?
Q38253965Why do statins reduce cardiovascular disease more than other lipid modulating therapies?
Q37923968Why, when and how should hypertriglyceridemia be treated in the high-risk cardiovascular patient?
Q91975849Xuezhitong capsule, an extract of Allium macrostemon Bunge, exhibits reverse cholesterol transport and accompanies high-density lipoprotein levels to protect against hyperlipidemia in ApoE-/- mice
Q52813315[Clinical importance of HDL cholesterol].
Q87437305[Lipid therapy for patients with coronary heart disease and diabetes. Current state and perspectives]
Q85725390[Lipids: diagnosis and therapy in type 2 diabetes]
Q83436144[Optimal lipid treatment: possibilities and current limitations]
Q53204305[PCSK9 inhibitors in hypercholesterolemia. New hope for patients with diabetes mellitus?].
Q88025019[Part I. Fibrates in primary and secondary prevention]
Q88025020[Part II. Combination statin plus fibrate regimens (free and fixed)]
Q83320620[Progress in hypertension and diabetes in 2010]
Q87174271[Treatment of lipid disorders]
Q34486059log(TG)/HDL-C is related to both residual cardiometabolic risk and β-cell function loss in type 2 diabetes males
Q38559352α-Lipoic acid as a triglyceride-lowering nutraceutical
Q38283976ω-3 carboxylic acids for hypertriglyceridemia

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