Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4

scientific article

Tyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4 is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1008318950
P356DOI10.1186/1471-2091-12-19
P932PMC publication ID3103433
P698PubMed publication ID21548926
P5875ResearchGate publication ID51104368

P50authorGwyn W GouldQ38546624
Nia J BryantQ63696783
P2093author name stringVeronica Aran
P2860cites workMembrane fusion: grappling with SNARE and SM proteinsQ24633113
SNAREpins: minimal machinery for membrane fusionQ28131697
Regulated transport of the glucose transporter GLUT4Q28216848
Negative regulation of syntaxin4/SNAP-23/VAMP2-mediated membrane fusion by Munc18c in vitroQ28474414
Adipocytes from Munc18c-null mice show increased sensitivity to insulin-stimulated GLUT4 externalizationQ28587742
Munc18c function is required for insulin-stimulated plasma membrane fusion of GLUT4 and insulin-responsive amino peptidase storage vesiclesQ33961324
Sec1/Munc18 proteins: mediators of membrane fusion moving to center stageQ34031651
SNAREs and trafficQ34436096
Temporal dynamics of tyrosine phosphorylation in insulin signaling.Q34551910
Structure of the Munc18c/Syntaxin4 N-peptide complex defines universal features of the N-peptide binding mode of Sec1/Munc18 proteinsQ34630628
The stimulus-induced tyrosine phosphorylation of Munc18c facilitates vesicle exocytosisQ36676310
Efficient expression in insect cells of a soluble, active human insulin receptor protein-tyrosine kinase domain by use of a baculovirus vectorQ40127712
A role for the syntaxin N-terminus.Q40966553
Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C.Q42068353
Regulation of insulin-stimulated GLUT4 translocation by Munc18c in 3T3L1 adipocytesQ42464766
GLUT4 distribution between the plasma membrane and the intracellular compartments is maintained by an insulin-modulated bipartite dynamic mechanismQ42486144
Selective activation of cognate SNAREpins by Sec1/Munc18 proteinsQ42506708
Tyrosine phosphorylation of Munc18c regulates platelet-derived growth factor-stimulated glucose transporter 4 translocation in 3T3L1 adipocytesQ42823903
Characterization of two distinct binding modes between syntaxin 4 and Munc18cQ58212669
Membrane Trafficking: Three Steps to FusionQ63383541
P921main subjectphosphorylationQ242736
P304page(s)19
P577publication date2011-05-06
P1433published inBMC BiochemistryQ15765786
P1476titleTyrosine phosphorylation of Munc18c on residue 521 abrogates binding to Syntaxin 4
P478volume12

Reverse relations

cites work (P2860)
Q33792902A phosphotyrosine switch for cargo sequestration at clathrin-coated buds
Q40838872Alternative routes to the cell surface underpin insulin-regulated membrane trafficking of GLUT4.
Q26866150Distinct initial SNARE configurations underlying the diversity of exocytosis
Q39207341Exocytosis proteins as novel targets for diabetes prevention and/or remediation?
Q35672106GLUT4 exocytosis.
Q37110583Impaired tethering and fusion of GLUT4 vesicles in insulin-resistant human adipose cells
Q53408692Insulin regulates astrocyte gliotransmission and modulates behavior.
Q28565898Insulin stimulates syntaxin4 SNARE complex assembly via a novel regulatory mechanism
Q36859379Munc18c in adipose tissue is downregulated in obesity and is associated with insulin
Q34620390Munc18c: a controversial regulator of peripheral insulin action
Q42565548Regulation of the SNARE-interacting protein Munc18c tyrosine phosphorylation in adipocytes by protein-tyrosine phosphatase 1B
Q47442898SNARE phosphorylation: a control mechanism for insulin-stimulated glucose transport and other regulated exocytic events.
Q33655562Spatiotemporal Regulators for Insulin-Stimulated GLUT4 Vesicle Exocytosis
Q37098751Specialized sorting of GLUT4 and its recruitment to the cell surface are independently regulated by distinct Rabs
Q38252302Studies of the regulated assembly of SNARE complexes in adipocytes.
Q41280624mVps45 knockdown selectively modulates VAMP expression in 3T3-L1 adipocytes.

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