Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development

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Analysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1018997789
P356DOI10.1186/1749-8104-5-12
P932PMC publication ID2880287
P698PubMed publication ID20412557
P5875ResearchGate publication ID43298212

P2093author name stringAdam Amsterdam
Lisa M Baye
Christine Insinna
Brian A Link
Joseph C Besharse
P2860cites workA novel dynein light intermediate chain colocalizes with the retrograde motor for intraflagellar transport at sites of axoneme assembly in chlamydomonas and Mammalian cellsQ24304623
Mammalian cells express three distinct dynein heavy chains that are localized to different cytoplasmic organellesQ24322864
Mechanism of positioning the cell nucleus in vertebrate photoreceptorsQ24684295
Stages of embryonic development of the zebrafishQ27860947
Cytoplasmic dynein heavy chain 1b is required for flagellar assembly in ChlamydomonasQ27876213
A dynein light intermediate chain, D1bLIC, is required for retrograde intraflagellar transportQ27919660
The homodimeric kinesin, Kif17, is essential for vertebrate photoreceptor sensory outer segment developmentQ27919718
Different roles for KIF17 and kinesin II in photoreceptor development and maintenanceQ27967646
Cytoplasmic dynein and dynactin in cell division and intracellular transportQ28137823
IFT20 links kinesin II with a mammalian intraflagellar transport complex that is conserved in motile flagella and sensory ciliaQ28181491
Myosin Va is required for normal photoreceptor synaptic activityQ28508131
Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1Q28508578
Molecular structure of cytoplasmic dynein 2 and its distribution in neuronal and ciliated cellsQ28567730
A dynein light chain is essential for the retrograde particle movement of intraflagellar transport (IFT)Q28608952
The Tol2kit: a multisite gateway-based construction kit for Tol2 transposon transgenesis constructsQ29618810
The proteome of the mouse photoreceptor sensory cilium complexQ29619586
Overexpression of the dynamitin (p50) subunit of the dynactin complex disrupts dynein-dependent maintenance of membrane organelle distributionQ29620185
The intraflagellar transport protein, IFT88, is essential for vertebrate photoreceptor assembly and maintenanceQ29620386
Zebrafish ale oko, an essential determinant of sensory neuron survival and the polarity of retinal radial glia, encodes the p50 subunit of dynactinQ30434913
Role of a class DHC1b dynein in retrograde transport of IFT motors and IFT raft particles along cilia, but not dendrites, in chemosensory neurons of living Caenorhabditis elegansQ30805155
Analysis of the dynein-dynactin interaction in vitro and in vivoQ33763775
Identification of 315 genes essential for early zebrafish developmentQ33979931
Nuclear positioning: the means is at the endsQ35041094
Transgenes as screening tools to probe and manipulate the zebrafish genomeQ36243103
Golgi vesiculation and lysosome dispersion in cells lacking cytoplasmic dynein.Q36255275
The DHC1b (DHC2) isoform of cytoplasmic dynein is required for flagellar assemblyQ36255765
Intraflagellar transport (IFT) cargo: IFT transports flagellar precursors to the tip and turnover products to the cell bodyQ36322385
Autoinhibitory and other autoregulatory elements within the dynein motor domainQ36463484
The dynein family at a glanceQ36639357
The role of Rds in outer segment morphogenesis and human retinal diseaseQ36674594
Proteomics of photoreceptor outer segments identifies a subset of SNARE and Rab proteins implicated in membrane vesicle trafficking and fusionQ36713655
Regulation of neurogenesis by interkinetic nuclear migration through an apical-basal notch gradientQ37066544
Intraflagellar transport and the sensory outer segment of vertebrate photoreceptorsQ37167508
Retrograde intraflagellar transport by cytoplasmic dynein-2 is required for outer segment extension in vertebrate photoreceptors but not arrestin translocationQ37421380
What drives cell morphogenesis: a look inside the vertebrate photoreceptorQ37543267
Mosaic Eyes is a novel component of the Crumbs complex and negatively regulates photoreceptor apical sizeQ39537977
Functional genomics reveals genes involved in protein secretion and Golgi organizationQ40321794
Genetic evidence for selective transport of opsin and arrestin by kinesin-II in mammalian photoreceptorsQ41755757
Chlamydomonas FAP133 is a dynein intermediate chain associated with the retrograde intraflagellar transport motorQ42519360
Cytoplasmic dynein intermediate chain phosphorylation regulates binding to dynactinQ43599362
A mutation of early photoreceptor development, mikre oko, reveals cell-cell interactions involved in the survival and differentiation of zebrafish photoreceptors.Q43715946
Transgenic expression of a GFP-rhodopsin COOH-terminal fusion protein in zebrafish rod photoreceptorsQ44268768
Development of a rod photoreceptor mosaic revealed in transgenic zebrafishQ44472628
The zebrafish young mutation acts non-cell-autonomously to uncouple differentiation from specification for all retinal cellsQ47073363
Identification of a zebrafish cone photoreceptor-specific promoter and genetic rescue of achromatopsia in the nof mutant.Q50700276
Rom-1 is required for rod photoreceptor viability and the regulation of disk morphogenesis.Q52168499
Vesicular transport of newly synthesized opsin from the Golgi apparatus toward the rod outer segment. Ultrastructural immunocytochemical and autoradiographic evidence in Xenopus retinasQ69974905
Biosynthesis and vectorial transport of opsin on vesicles in retinal rod photoreceptorsQ69982845
The development of photoreceptors in the zebrafish, Brachydanio rerio. I. StructureQ71327912
Retroviral-mediated insertional mutagenesis in zebrafishQ81154594
P921main subjectDanio rerioQ169444
photoreceptor proteinQ7187894
P304page(s)12
P577publication date2010-04-22
P1433published inNeural DevelopmentQ15761981
P1476titleAnalysis of a zebrafish dync1h1 mutant reveals multiple functions for cytoplasmic dynein 1 during retinal photoreceptor development.
P478volume5

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cites work (P2860)
Q37242132Arl13b Interacts With Vangl2 to Regulate Cilia and Photoreceptor Outer Segment Length in Zebrafish
Q35202359CNS myelination requires cytoplasmic dynein function
Q58802918Casz1 controls higher-order nuclear organization in rod photoreceptors
Q49988075Cone myoid elongation involves unidirectional microtubule movement mediated by dynein-1.
Q37298023Cytoplasmic dynein heavy chain: the servant of many masters
Q36907183Dlic1 deficiency impairs ciliogenesis of photoreceptors by destabilizing dynein
Q64234909Dynein promotes sustained axonal growth and Schwann cell remodeling early during peripheral nerve regeneration
Q33557669In vivo cell biology in zebrafish - providing insights into vertebrate development and disease
Q36893782Integrative subcellular proteomic analysis allows accurate prediction of human disease-causing genes
Q27336244Loss of optineurin in vivo results in elevated cell death and alters axonal trafficking dynamics
Q36970452MCRS1 associates with cytoplasmic dynein and mediates pericentrosomal material recruitment
Q36070359Mutation screen reveals novel variants and expands the phenotypes associated with DYNC1H1.
Q42088821Mutations in the Dynein1 Complex are Permissible for Basal Body Migration in Photoreceptors but Alter Rab6 Localization
Q28550397NINL and DZANK1 Co-function in Vesicle Transport and Are Essential for Photoreceptor Development in Zebrafish
Q34514308Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells
Q37138123Protein sorting, targeting and trafficking in photoreceptor cells
Q33627414Regulation of mitochondria-dynactin interaction and mitochondrial retrograde transport in axons
Q34079639Retrograde intraciliary trafficking of opsin during the maintenance of cone-shaped photoreceptor outer segments of Xenopus laevis
Q41994444Schwann cell myelination requires Dynein function
Q35083383Synaptojanin 1 is required for endolysosomal trafficking of synaptic proteins in cone photoreceptor inner segments
Q35005573The cell biology of vision
Q35225255The ciliopathy gene cc2d2a controls zebrafish photoreceptor outer segment development through a role in Rab8-dependent vesicle trafficking
Q64277876The ubiquitin ligase PHR promotes directional regrowth of spinal zebrafish axons
Q37873908The vertebrate retina: a model for neuronal polarization in vivo.
Q35449573The visual system of zebrafish and its use to model human ocular diseases

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