Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A

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Genome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1016761177
P356DOI10.1186/1471-2180-11-97
P932PMC publication ID3119188
P698PubMed publication ID21569340
P5875ResearchGate publication ID51123927

P50authorMaurizio SanguinettiQ38325512
Dominique SanglardQ40141436
Brunella PosteraroQ41881644
Riccardo TorelliQ56285785
Elena De CarolisQ57097045
Ada Rita FlorioQ114423952
P2093author name stringGiovanni Fadda
Selene Ferrari
P2860cites workThe genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformansQ22065807
Cryptococcus neoformans overcomes stress of azole drugs by formation of disomy in specific multiple chromosomesQ27315103
Involvement of yeast YOL151W/GRE2 in ergosterol metabolismQ27930740
Identification of a novel system for boron transport: Atr1 is a main boron exporter in yeast.Q27937700
Combined phylogeny and neighborhood analysis of the evolution of the ABC transporters conferring multiple drug resistance in hemiascomycete yeastsQ27939331
Upregulation of ERG genes in Candida species by azoles and other sterol biosynthesis inhibitorsQ28344744
A link between virulence and homeostatic responses to hypoxia during infection by the human fungal pathogen Cryptococcus neoformansQ28469145
Protein sensors for membrane sterolsQ29617313
Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDSQ29617372
Identification and characterization of a Cryptococcus neoformans ATP binding cassette (ABC) transporter-encoding gene, CnAFR1, involved in the resistance to fluconazoleQ30879441
Molecular characterization of the plasma membrane H(+)-ATPase, an antifungal target in Cryptococcus neoformansQ30908894
Gene expression omnibus: microarray data storage, submission, retrieval, and analysisQ31057685
Efflux in fungi: la pièce de résistanceQ33474798
Cas3p belongs to a seven-member family of capsule structure designer proteinsQ33560210
Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesisQ33725227
Mechanism of the synergistic effect of amiodarone and fluconazole in Candida albicansQ33826488
How sweet it is! Cell wall biogenesis and polysaccharide capsule formation in Cryptococcus neoformansQ33894565
Heteroresistance to fluconazole and voriconazole in Cryptococcus neoformansQ33977302
Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugsQ34048162
Comparative transcriptome analysis of the CO2 sensing pathway via differential expression of carbonic anhydrase in Cryptococcus neoformansQ34082194
Role of AFR1, an ABC transporter-encoding gene, in the in vivo response to fluconazole and virulence of Cryptococcus neoformansQ34334162
Molecular basis of resistance to azole antifungalsQ34508503
Chitosan, the deacetylated form of chitin, is necessary for cell wall integrity in Cryptococcus neoformans.Q35855079
Complementation of a capsule-deficient mutation of Cryptococcus neoformans restores its virulenceQ36657718
Cryptococcus neoformans, a fungus under stressQ36914008
Efflux-mediated antifungal drug resistance.Q37156645
Heteroresistance to fluconazole in Cryptococcus neoformans is intrinsic and associated with virulenceQ37247728
Remodeling of global transcription patterns of Cryptococcus neoformans genes mediated by the stress-activated HOG signaling pathwaysQ37301922
Drug:H+ antiporters in chemical stress response in yeastQ37343243
Conservation of the sterol regulatory element-binding protein pathway and its pathobiological importance in Cryptococcus neoformansQ37410081
Identification of Cryptococcus neoformans temperature-regulated genes with a genomic-DNA microarrayQ37579804
Genomic profiling of the response of Candida albicans to itraconazole treatment using a DNA microarrayQ38300837
Sre1p, a regulator of oxygen sensing and sterol homeostasis, is required for virulence in Cryptococcus neoformansQ38302324
Comparison of gene expression profiles of Candida albicans azole-resistant clinical isolates and laboratory strains exposed to drugs inducing multidrug transportersQ38338527
Genome-wide expression patterns in Saccharomyces cerevisiae: comparison of drug treatments and genetic alterations affecting biosynthesis of ergosterolQ39473756
Fluconazole at subinhibitory concentrations induces the oxidative- and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida albicans to phagocytesQ39777653
Biochemical targets for antifungal azole derivatives: hypothesis on the mode of action.Q39844899
Lipid signaling in pathogenic fungiQ39978770
Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans.Q40384960
Fungal echinocandin resistance.Q41848811
Fluconazole and itraconazole susceptibility of clinical isolates of Cryptococcus neoformans at a tertiary care centre in India: a need for careQ44570712
Enzymes that Counteract Nitrosative Stress Promote Fungal VirulenceQ44653973
Increasing in vitro resistance to fluconazole in Cryptococcus neoformans Cambodian isolates: April 2000 to March 2002.Q44978557
Antifungal drug susceptibility of Cryptococcus neoformans from clinical sources in Nairobi, KenyaQ46421581
Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrityQ46942417
Drug resistance in Cryptococcus neoformans.Q53998982
Cryptococcal meningitis.Q54075694
The Hsp70 member, Ssa1, acts as a DNA-binding transcriptional co-activator of laccase in Cryptococcus neoformansQ62638331
Decreased virulence in stable, acapsular mutants of cryptococcus neoformansQ71441160
CryptococcosisQ78746513
Fungal infections in solid organ transplantationQ80353064
Prevalence of HIV-associated cryptococcal meningitis and utility of microbiological determinants for its diagnosis in a tertiary care centerQ81586120
New insights on the pathogenesis of invasive Cryptococcus neoformans infectionQ81593297
P921main subjectCryptococcus neoformansQ131924
fluconazoleQ411478
P304page(s)97
P577publication date2011-05-11
P1433published inBMC MicrobiologyQ15759430
P1476titleGenome-wide expression profiling of the response to short-term exposure to fluconazole in Cryptococcus neoformans serotype A
P478volume11

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cites work (P2860)
Q353196169-O-butyl-13-(4-isopropylbenzyl)berberine, KR-72, is a potent antifungal agent that inhibits the growth of Cryptococcus neoformans by regulating gene expression
Q36445833A defect in iron uptake enhances the susceptibility of Cryptococcus neoformans to azole antifungal drugs.
Q49537989Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles.
Q91686097Antiphagocytic protein 1 increases the susceptibility of Cryptococcus neoformans to amphotericin B and fluconazole
Q52935267Azoles activate Atf1-mediated transcription through MAP kinase pathway for antifungal effects in fission yeast.
Q27025924Cryptococcus neoformans: historical curiosity to modern pathogen
Q54978161Evolutionarily Conserved and Divergent Roles of Unfolded Protein Response (UPR) in the Pathogenic Cryptococcus Species Complex.
Q37126219Fungal cell wall dynamics and infection site microenvironments: signal integration and infection outcome
Q40103625Heat shock protein 90 localizes to the surface and augments virulence factors of Cryptococcus neoformans.
Q28483330Identification and characterization of antifungal compounds using a Saccharomyces cerevisiae reporter bioassay
Q89048076Identifying a novel connection between the fungal plasma membrane and pH-sensing
Q46458243Multilocus resistance evolution to azole fungicides in fungal plant pathogen populations.
Q35148713Network-assisted genetic dissection of pathogenicity and drug resistance in the opportunistic human pathogenic fungus Cryptococcus neoformans
Q35611515New technology and resources for cryptococcal research
Q33813958RNA biology and the adaptation of Cryptococcus neoformans to host temperature and stress
Q49598890Role of three Cryptococcus neoformans and C. gattii efflux pump coding genes in response to drug treatment.
Q36882388Sterol C-22 Desaturase ERG5 Mediates the Sensitivity to Antifungal Azoles in Neurospora crassa and Fusarium verticillioides
Q34960987Ten challenges on Cryptococcus and cryptococcosis
Q28482096Time-course proteome analysis reveals the dynamic response of Cryptococcus gattii cells to fluconazole
Q41652452Unraveling the biology of a fungal meningitis pathogen using chemical genetics

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