Triple-negative breast cancer: role of specific chemotherapy agents

scientific article

Triple-negative breast cancer: role of specific chemotherapy agents is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1097/PPO.0B013E3181D24FF7
P932PMC publication ID2882502
P698PubMed publication ID20164691

P2093author name stringSteven J Isakoff
P2860cites workMolecular portraits of human breast tumoursQ28032461
Efficacy of neoadjuvant Cisplatin in triple-negative breast cancerQ28372484
Paclitaxel plus bevacizumab versus paclitaxel alone for metastatic breast cancerQ29614302
Prognostic impact of clinicopathologic parameters in stage II/III breast cancer treated with neoadjuvant docetaxel and doxorubicin chemotherapy: paradoxical features of the triple negative breast cancerQ33304691
High-dose cis-diamminedichloro-platinum therapy in patients with advanced breast cancer: pharmacokinetics, toxicity, and therapeutic efficacyQ33485091
Sites of distant recurrence and clinical outcomes in patients with metastatic triple-negative breast cancer: high incidence of central nervous system metastasesQ33715354
The platinum agents: a role in breast cancer treatment?Q34218149
Response to neo-adjuvant chemotherapy in women with BRCA1-positive breast cancersQ34579373
Estrogen-receptor status and outcomes of modern chemotherapy for patients with node-positive breast cancerQ34601123
Adjuvant chemotherapy in older women with early-stage breast cancerQ34858284
The relation between estrogen receptors and response rate to cytotoxic chemotherapy in metastatic breast cancerQ67332740
Phase I trial of escalating doses of cisplatin in hypertonic salineQ68189739
Cisplatin in the treatment of metastatic breast carcinoma: A prospective randomized trial of two dosage schedulesQ70236730
A phase II study of cis-diamminedichloroplatinum II for advanced breast cancer. Two dose schedulesQ70510924
CAP (cyclophosphamide, adriamycin, cisplatinum) in the treatment of advanced breast cancerQ70815222
Phase II clinical trial of cis-dichlorodiammine platinum (cis-DDP) for antitumorigenic activity in previously untreated patients with metastatic breast cancerQ71236719
Inclusion of taxanes, particularly weekly paclitaxel, in preoperative chemotherapy improves pathologic complete response rate in estrogen receptor-positive breast cancersQ79758509
Potential chemotherapy options in the triple negative subtype of breast cancerQ80077016
Response to neoadjuvant therapy with cisplatin in BRCA1-positive breast cancer patientsQ81688258
Molecular subtypes of breast cancer in relation to paclitaxel response and outcomes in women with metastatic disease: results from CALGB 9342Q35633680
Platinum-based chemotherapy in metastatic breast cancer: current status.Q35650449
The p63/p73 network mediates chemosensitivity to cisplatin in a biologically defined subset of primary breast cancersQ35745252
Phase II study of neoadjuvant paclitaxel and cisplatin for operable and locally advanced breast cancer: analysis of 126 patientsQ36694650
Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancerQ36695226
Triple-negative high-risk breast cancer derives particular benefit from dose intensification of adjuvant chemotherapy: results of WSG AM-01 trialQ37049920
Adjuvant chemotherapy in oestrogen-receptor-poor breast cancer: patient-level meta-analysis of randomised trialsQ37051591
Breast cancer subtypes and response to docetaxel in node-positive breast cancer: use of an immunohistochemical definition in the BCIRG 001 trial.Q37155629
What is triple-negative breast cancer?Q37325246
Weekly paclitaxel in the adjuvant treatment of breast cancer.Q37346811
BRCA1 expression modulates chemosensitivity of BRCA1-defective HCC1937 human breast cancer cellsQ37355031
Survival outcomes for patients with metastatic triple-negative breast cancer: implications for clinical practice and trial designQ37418501
Identification of biology-based breast cancer types with distinct predictive and prognostic features: role of steroid hormone and HER2 receptor expression in patients treated with neoadjuvant anthracycline/taxane-based chemotherapyQ37467199
Caveolin-1 expression is associated with a basal-like phenotype in sporadic and hereditary breast cancer.Q40303976
Doxorubicin with cyclophosphamide followed by docetaxel every 21 days compared with doxorubicin and docetaxel every 14 days as preoperative treatment in operable breast cancer: the GEPARDUO study of the German Breast GroupQ40510447
BRCA1 functions as a differential modulator of chemotherapy-induced apoptosisQ40626126
Inhibition of BRCA1 leads to increased chemoresistance to microtubule-interfering agents, an effect that involves the JNK pathwayQ40773708
Homology-directed dna repair, mitomycin-c resistance, and chromosome stability is restored with correction of a Brca1 mutationQ40798697
Phase II study of cis-dichlorodiammineplatinum(II) in advanced breast cancerQ40887308
BRCA1 up-regulation is associated with repair-mediated resistance to cis-diamminedichloroplatinum(II).Q41056489
Germline BRCA1 mutations and a basal epithelial phenotype in breast cancerQ42450903
Breast cancer molecular subtypes respond differently to preoperative chemotherapyQ42482998
The triple negative paradox: primary tumor chemosensitivity of breast cancer subtypesQ42511189
A significant response to neoadjuvant chemotherapy in BRCA1/2 related breast cancerQ43074624
Estrogen receptors and responses to chemotherapy and hormonal therapy in advanced breast cancerQ43517097
Improved outcomes from adding sequential Paclitaxel but not from escalating Doxorubicin dose in an adjuvant chemotherapy regimen for patients with node-positive primary breast cancer.Q44362100
Treatment outcomes and clinicopathologic characteristics of triple-negative breast cancer patients who received platinum-containing chemotherapyQ44423612
The effect on tumor response of adding sequential preoperative docetaxel to preoperative doxorubicin and cyclophosphamide: preliminary results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27.Q44618276
Cisplatin as first-line therapy for metastatic breast cancerQ45036830
Chemotherapy is more effective in patients with breast cancer not expressing steroid hormone receptors: a study of preoperative treatmentQ45099316
Response to neoadjuvant therapy and disease free survival in patients with triple-negative breast cancer.Q46119049
Preoperative weekly cisplatin-epirubicin-paclitaxel with G-CSF support in triple-negative large operable breast cancer.Q46121546
Platinum-based chemotherapy in triple-negative breast cancer.Q46358330
Paclitaxel after doxorubicin plus cyclophosphamide as adjuvant chemotherapy for node-positive breast cancer: results from NSABP B-28.Q46493659
Primary resistance to docetaxel-based chemotherapy in metastatic breast cancer patients correlates with a high frequency of BRCA1 mutationsQ46508970
Dose-dense and/or metronomic schedules of specific chemotherapies consolidate the chemosensitivity of triple-negative breast cancer: a step toward reversing triple-negative paradoxQ46509413
Adjuvant docetaxel for node-positive breast cancerQ46522790
Preoperative chemotherapy: updates of National Surgical Adjuvant Breast and Bowel Project Protocols B-18 and B-27.Q46765380
Response to neoadjuvant therapy and long-term survival in patients with triple-negative breast cancerQ46771645
Tailored preoperative treatment of locally advanced triple negative (hormone receptor negative and HER2 negative) breast cancer with epirubicin, cisplatin, and infusional fluorouracil followed by weekly paclitaxel.Q46862276
'Triple negative' breast cancer: a new area for phase III breast cancer clinical trialsQ46918686
Prognostic value of pathologic complete response after primary chemotherapy in relation to hormone receptor status and other factors.Q46966638
Clinico-pathological characteristics of BRCA1- and BRCA2-related breast cancer.Q53409967
HER2 and Response to Paclitaxel in Node-Positive Breast CancerQ57578418
Randomized Trial of Dose-Dense Versus Conventionally Scheduled and Sequential Versus Concurrent Combination Chemotherapy as Postoperative Adjuvant Treatment of Node-Positive Primary Breast Cancer: First Report of Intergroup Trial C9741/Cancer and LeuQ57578575
The breast cancer susceptibility gene BRCA1 is required for subnuclear assembly of Rad51 and survival following treatment with the DNA cross-linking agent cisplatinQ64388522
P433issue1
P921main subjectbreast cancerQ128581
triple-negative breast cancerQ7843332
chemotherapyQ974135
P304page(s)53-61
P577publication date2010-01-01
P1433published inThe Cancer JournalQ2589130
P1476titleTriple-negative breast cancer: role of specific chemotherapy agents
P478volume16

Reverse relations

cites work (P2860)
Q64912613(-)-Oleocanthal Prevents Breast Cancer Locoregional Recurrence After Primary Tumor Surgical Excision and Neoadjuvant Targeted Therapy in Orthotopic Nude Mouse Models.
Q47115127A Cell-Line-Specific Atlas of PARP-Mediated Protein Asp/Glu-ADP-Ribosylation in Breast Cancer
Q36432567A DNA repair BRCA1 estrogen receptor and targeted therapy in breast cancer
Q38432397A microRNA signature associated with pathological complete response to novel neoadjuvant therapy regimen in triple-negative breast cancer
Q94671596A novel prognostic two-gene signature for triple negative breast cancer
Q37024369A phase I followed by a randomized phase II trial of two cycles carboplatin-olaparib followed by olaparib monotherapy versus capecitabine in BRCA1- or BRCA2-mutated HER2-negative advanced breast cancer as first line treatment (REVIVAL): study protoc
Q55405558A randomized and open-label phase II trial reports the efficacy of neoadjuvant lobaplatin in breast cancer.
Q47151712APC loss in breast cancer leads to doxorubicin resistance via STAT3 activation.
Q35655334APC selectively mediates response to chemotherapeutic agents in breast cancer
Q41636352Adaptive Reprogramming of De Novo Pyrimidine Synthesis Is a Metabolic Vulnerability in Triple-Negative Breast Cancer
Q37990824Adjuvant therapy in stage I carcinoma of the breast: the influence of multigene analyses and molecular phenotyping
Q38023589Adjuvant therapy in stage I carcinoma of the breast: the influence of multigene analyses and molecular phenotyping.
Q60937807Apoptosis Induction via ATM Phosphorylation, Cell Cycle Arrest, and ER Stress by Goniothalamin and Chemodrugs Combined Effects on Breast Cancer-Derived MDA-MB-231 Cells
Q93059408Apoptotic Resistance of Metastatic Tumor Cells in Triple Negative Breast Cancer: Roles of Death Receptor-5
Q33829321Binding of galectin-1 to integrin β1 potentiates drug resistance by promoting survivin expression in breast cancer cells
Q90284585Both BRCA1-wild type and -mutant triple-negative breast cancers show sensitivity to the NAE inhibitor MLN4924 which is enhanced upon MLN4924 and cisplatin combination treatment
Q91099817Brain metastases
Q38386346Breast cancer under age 40: a different approach
Q98158906CHARACTERISTICS AND PROGNOSIS OF TRIPLE-NEGATIVE BREAST CANCER PATIENTS: A CROATIAN SINGLE INstitution RETROSPECTIVE COHORT STUDY
Q33867131Cancer stem cells: a novel paradigm for cancer prevention and treatment
Q37214592Cellular uptake mechanism and comparative evaluation of antineoplastic effects of paclitaxel-cholesterol lipid emulsion on triple-negative and non-triple-negative breast cancer cell lines
Q36057728Chemotherapy-induced peripheral neurotoxicity and ototoxicity: new paradigms for translational genomics
Q38694338Codelivery of Anti-cancer Agents via Double-walled Polymeric Microparticles/ Injectable Hydrogel: A Promising Approach for Treatment of Triple Negative Breast Cancer
Q33919246Curcumin: the spicy modulator of breast carcinogenesis.
Q33579896DNA methyltransferases: a novel target for prevention and therapy
Q91992110Delivery of Anti-miRNA for Triple-Negative Breast Cancer Therapy Using RNA Nanoparticles Targeting Stem Cell Marker CD133
Q33601365Docetaxel-Loaded PLGA Nanoparticles Improve Efficacy in Taxane-Resistant Triple-Negative Breast Cancer.
Q58104057Dynamin impacts homology-directed repair and breast cancer response to chemotherapy
Q92133957Efficacy and safety profiles of programmed cell death-1/programmed cell death ligand-1 inhibitors in the treatment of triple-negative breast cancer: A comprehensive systematic review
Q37511632Epigenetic silencing of ARRDC3 expression in basal-like breast cancer cells
Q91843376Establishment of chemosensitivity tests in triple-negative and BRCA-mutated breast cancer patient-derived xenograft models
Q89617913Fangjihuangqi Decoction inhibits MDA-MB-231 cell invasion in vitro and decreases tumor growth and metastasis in triple-negative breast cancer xenografts tumor zebrafish model
Q47437905Genome-wide analysis of the three-way interplay among gene expression, estrogen receptor expression and chemotherapeutic sensitivity in breast cancer
Q29248638Genome-wide profiles of methylation, microRNAs, and gene expression in chemoresistant breast cancer
Q37262447Gold Nanoantenna-Mediated Photothermal Drug Delivery from Thermosensitive Liposomes in Breast Cancer
Q33933721Healthcare costs in women with metastatic breast cancer receiving chemotherapy as their principal treatment modality
Q47125869High PD-L1 Expression Is Closely Associated With Tumor-Infiltrating Lymphocytes and Leads to Good Clinical Outcomes in Chinese Triple Negative Breast Cancer Patients
Q50003353Identification of Staphylococcus aureus α-hemolysin as a protein drug that is secreted by anticancer bacteria and rapidly kills cancer cells
Q58702853Identification of tRNA-derived small noncoding RNAs as potential biomarkers for prediction of recurrence in triple-negative breast cancer
Q64105917Impact of age on pathological complete response and locoregional recurrence in locally advanced breast cancer after neoadjuvant chemotherapy
Q41531931Impressive Response to Concomitant Platinum-based Chemotherapy and Yttrium-90 in a Patient with Heavily Pretreated Triple-negative Breast Cancer Widely Metastasized to the Liver
Q64951827In silico simulation of a clinical trial with anti-CTLA-4 and anti-PD-L1 immunotherapies in metastatic breast cancer using a systems pharmacology model.
Q38837835Inorganic Phosphate Prevents Erk1/2 and Stat3 Activation and Improves Sensitivity to Doxorubicin of MDA-MB-231 Breast Cancer Cells.
Q37574955Investigating the discernible and distinct effects of platinum-based chemotherapy regimens for metastatic triple-negative breast cancer on time to progression
Q44273702Investigation of molecular alterations of AKT-3 in triple-negative breast cancer
Q91972947Isoliquiritigenin Derivative Regulates miR-374a/BAX Axis to Suppress Triple-Negative Breast Cancer Tumorigenesis and Development
Q36551346Long-Term Complete Remission with nab-Paclitaxel, Bevacizumab, and Gemcitabine Combination Therapy in a Patient with Triple-Negative Metastatic Breast Cancer
Q38148063Long-term treatment after preoperative high-dose chemotherapy in a lactating breast cancer patient
Q38733113MENA Confers Resistance to Paclitaxel in Triple-Negative Breast Cancer
Q50455931MT4-MMP and EGFR expression levels are key biomarkers for breast cancer patient response to chemotherapy and erlotinib
Q35155460Management options in triple-negative breast cancer
Q54537693Methylation of O6-methylguanine-DNA methyltransferase (MGMT) promoter gene in triple-negative breast cancer patients.
Q48263230MiR-770 suppresses the chemo-resistance and metastasis of triple negative breast cancer via direct targeting of STMN1.
Q34562257Minireview: Basal-like breast cancer: from molecular profiles to targeted therapies
Q38677841Neoadjuvant Chemotherapy In Triple-Negative Breast Cancer: A Multicentric Retrospective Observational Study In Real-Life Setting.
Q40774797Neoadjuvant Chemotherapy in Triple Negative Breast Cancer: An Observational Study
Q54979733Neuropilin-1 promotes the oncogenic Tenascin-C/integrin β3 pathway and modulates chemoresistance in breast cancer cells.
Q90477297New substituted quinoxalines inhibit triple-negative breast cancer by specifically downregulating the c-MYC transcription
Q36956874Nodal expression in triple-negative breast cancer: Cellular effects of its inhibition following doxorubicin treatment
Q28388647Norcantharidin, derivative of cantharidin, for cancer stem cells
Q37426564Noscapine chemosensitization enhances docetaxel anticancer activity and nanocarrier uptake in triple negative breast cancer
Q33591623ONC201 activates ER stress to inhibit the growth of triple-negative breast cancer cells
Q48336503Oestrogen receptor negative early operable primary breast cancer in older women-Biological characteristics and long-term clinical outcome.
Q38259259PI3K/AKT/mTOR pathway inhibitors: the ideal combination partners for breast cancer therapies?
Q35990463Pathological complete response in younger and older breast cancer patients
Q64906560Piperlongumine Induces Apoptosis and Synergizes with Doxorubicin by Inhibiting the JAK2-STAT3 Pathway in Triple-Negative Breast Cancer.
Q37727996Poly(ADP-ribose) polymerase inhibitors as promising cancer therapeutics
Q38155673Primary therapy in breast cancer: what have we learned from landmark trials?
Q90049397Prognostic value of tumor-infiltrating lymphocytes in patients with triple-negative breast cancer: a systematic review and meta-analysis
Q40296843Programmed death ligand 1 expression in triple-negative breast cancer is associated with tumour-infiltrating lymphocytes and improved outcome.
Q28235715Protective role of miR-155 in breast cancer through RAD51 targeting impairs homologous recombination after irradiation
Q86588472RETRACTED ARTICLE: Enhancement of doxorubicin efficacy through suppression of serine synthesis in triple-negative breast cancer
Q44292349RETRACTED: Inhibition of PKM2 sensitizes triple-negative breast cancer cells to doxorubicin
Q47126394Randomized phase II study of the anti-epidermal growth factor receptor monoclonal antibody cetuximab with cisplatin versus cisplatin alone in patients with metastatic triple-negative breast cancer
Q28391395Reinventing diagnostics for personalized therapy in oncology
Q54349758Relationship between chemotherapy and prognosis in different subtypes of node-negative breast cancer.
Q43421701Risk and healthcare costs of chemotherapy-induced neutropenic complications in women with metastatic breast cancer
Q90010266Role of Muscarinic Acetylcholine Receptors in Breast Cancer: Design of Metronomic Chemotherapy
Q45967836Role of Taxanes in Triple-Negative Breast Cancer: A Study From Tertiary Cancer Center in South India.
Q39088864Stress-induced EGF receptor signaling through STAT3 and tumor progression in triple-negative breast cancer
Q41290532Structure-activity relationships and molecular docking studies of chromene and chromene based azo chromophores: A novel series of potent antimicrobial and anticancer agents
Q35128130Suberoyl bis-hydroxamic acid enhances cytotoxicity induced by proteasome inhibitors in breast cancer cells
Q46857381Suppression of the xCT-CD44v antiporter system sensitizes triple-negative breast cancer cells to doxorubicin
Q27853147TBCRC009: A Multicenter Phase II Clinical Trial of Platinum Monotherapy With Biomarker Assessment in Metastatic Triple-Negative Breast Cancer
Q40630370Tailoring combinatorial cancer therapies to target the origins of adaptive resistance
Q36157045Targeted nanoparticles for image-guided treatment of triple-negative breast cancer: clinical significance and technological advances
Q89500713Targeting PP2A inhibits the growth of triple-negative breast cancer cells
Q38823095Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy
Q91989182Targeting immune pathways in breast cancer: review of the prognostic utility of TILs in early stage triple negative breast cancer (TNBC)
Q58702607The "Yin and Yang" of Natural Compounds in Anticancer Therapy of Triple-Negative Breast Cancers
Q37720246The Role of Carboplatin in the Neoadjuvant Chemotherapy Treatment of Triple Negative Breast Cancer
Q26798356The role of taxanes in triple-negative breast cancer: literature review
Q34302752The treatment and survival of patients with triple negative breast cancer in a London population
Q37414318Theranostic barcoded nanoparticles for personalized cancer medicine
Q34331406Treatment options for patients with triple-negative breast cancer
Q38007037Triple negative breast cancer: a brief review of its characteristics and treatment options
Q60914202Triptolide Decreases Cell Proliferation and Induces Cell Death in Triple Negative MDA-MB-231 Breast Cancer Cells
Q92705301Two Natural Alkaloids Synergistically Induce Apoptosis in Breast Cancer Cells by Inhibiting STAT3 Activation
Q36311616Update on triple-negative breast cancer: prognosis and management strategies
Q50053475Variation in guideline-concordant care for elderly patients with metastatic breast cancer in the United States
Q33576814microRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers
Q36794562pH-responsive artemisinin dimer in lipid nanoparticles are effective against human breast cancer in a xenograft model
Q35029494α-TEA cooperates with chemotherapeutic agents to induce apoptosis of p53 mutant, triple-negative human breast cancer cells via activating p73.

Search more.