Thiol-disulfide effects on hepatic glutathione transport. Studies in cultured rat hepatocytes and perfused livers

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Thiol-disulfide effects on hepatic glutathione transport. Studies in cultured rat hepatocytes and perfused livers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI116689
P932PMC publication ID288257
P698PubMed publication ID8376579
P5875ResearchGate publication ID14821886

P2093author name stringS C Lu
N Kaplowitz
H Y Huang
J L Ge
J Kuhlenkamp
P2860cites workAn enzyme from rat liver catalysing conjugations with glutathioneQ24532886
GlutathioneQ28261279
Impaired uptake of glutathione by hepatic mitochondria from chronic ethanol-fed rats. Tracer kinetic studies in vitro and in vivo and susceptibility to oxidant stressQ34180032
Hormone-mediated down-regulation of hepatic glutathione synthesis in the ratQ34225743
Intracellular cystine loading inhibits transport in the rabbit proximal convoluted tubuleQ34241781
Sinusoidal efflux of glutathione in the perfused rat liver. Evidence for a carrier-mediated processQ34524480
Inhibition of glutathione efflux in the perfused rat liver and isolated hepatocytes by organic anions and bilirubin. Kinetics, sidedness, and molecular formsQ34560115
Insulin and glucocorticoid dependence of hepatic gamma-glutamylcysteine synthetase and glutathione synthesis in the rat. Studies in cultured hepatocytes and in vivoQ35605366
Role of adenosine triphosphate (ATP) and NaK ATPase in the inhibition of proximal tubule transport with intracellular cystine loading.Q35819885
Nocodazole, a microtubule-active drug, interferes with apical protein delivery in cultured intestinal epithelial cells (Caco-2).Q36219864
The regulation of hepatic glutathioneQ39821889
Mechanism of changes in hepatic sinusoidal and biliary glutathione efflux with age in ratsQ41855611
Total cellular activity and distribution of a subpopulation of galactosyl receptors in isolated rat hepatocytes are differentially affected by microtubule drugs, monensin, low temperature, and chloroquineQ41942756
Short-term stimulation of Na+-dependent amino acid transport by dibutyryl cyclic AMP in hepatocytes. Characteristics and partial mechanismQ42072473
Kinetics of glutathione efflux from isolated rat hepatocytesQ44732292
Bidirectional mechanism of plasma membrane transport of reduced glutathione in intact rat hepatocytes and membrane vesiclesQ44934723
Altered hepatic junctional permeability, bile acid excretion and glutathione efflux during oxidant challengeQ44938703
Expression of rat liver reduced glutathione transport in Xenopus laevis oocytesQ46203353
Hormonal regulation of glutathione effluxQ46633140
Effect of membrane potential and cellular ATP on glutathione efflux from isolated rat hepatocytesQ46801282
Distribution of oxidized and reduced forms of glutathione and cysteine in rat plasmaQ49218490
Hepatic glutathione homeostasis in the rat: efflux accounts for glutathione turnover.Q51642019
Isolation and use of liver cellsQ67358324
A reactive nucleophile proximal to vicinal thiols is an evolutionarily conserved feature in the mechanism of Arg aminoacyl-tRNA protein transferaseQ67568065
Enzymic method for quantitative determination of nanogram amounts of total and oxidized glutathione: applications to mammalian blood and other tissuesQ68732983
High-performance liquid chromatography of thiols and disulfides: dinitrophenol derivativesQ69405611
Inhibition of glutathione efflux in the recirculating rat liver perfusion by cysteine but not by oxothiazolidine carboxylate, an intracellular cysteine precursorQ70710645
Determination of pyridine dinucleotides in cell extracts by high-performance liquid chromatographyQ70976314
Inhibition of glutathione efflux from isolated rat hepatocytes by methionineQ71431012
Synthesis and Characterization of the L-Cysteine-Glutathione Mixed DisulfideQ72290433
(Na,K)-ATPase-mediated cation pumping in cultured rat hepatocytes. Rapid modulation by alanine and taurocholate transport and characterization of its relationship to intracellular sodium concentrationQ72564335
Transport of cystine in isolated rat hepatocytes in primary cultureQ72573077
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)1188-1197
P577publication date1993-09-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleThiol-disulfide effects on hepatic glutathione transport. Studies in cultured rat hepatocytes and perfused livers
P478volume92

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cites work (P2860)
Q42518001Chronic exposure of HepG2 cells to excess copper results in depletion of glutathione and induction of metallothionein.
Q51623840Cocaine-induced liver injury in mice elicits specific changes in DNA ploidy and induces programmed death of hepatocytes.
Q46213703Dealing with stress
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Q47954775Identification of glutathione as a driving force and leukotriene C4 as a substrate for oatp1, the hepatic sinusoidal organic solute transporter
Q57010278Investigation of the transport of intact glutathione in human and rat type II pneumocytes
Q40996484Nutritional and hormonal regulation of glutathione homeostasis
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Q37353263Role of two recently cloned rat liver GSH transporters in the ubiquitous transport of GSH in mammalian cells
Q42438304Signaling role of intracellular iron in NF-kappaB activation