The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?

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The 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology? is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1038/76211
P698PubMed publication ID10835679
P5875ResearchGate publication ID12481941

P2093author name stringVassalli JD
Conne B
Stutz A
P2860cites workCardiac elav-type RNA-binding protein (ETR-3) binds to RNA CUG repeats expanded in myotonic dystrophyQ22008662
Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.Q22010036
An ancient retrotransposal insertion causes Fukuyama-type congenital muscular dystrophyQ24320265
Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolinQ24323168
CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBPbeta mRNA and regulates translation of C/EBPbeta isoformsQ24548885
Altered phosphorylation and intracellular distribution of a (CUG)n triplet repeat RNA-binding protein in patients with myotonic dystrophy and in myotonin protein kinase knockout miceQ24654728
AU-rich elements: characterization and importance in mRNA degradationQ29547896
RNA stabilization by the AU-rich element binding protein, HuR, an ELAV proteinQ29615186
Myotonic dystrophy: the role of RNA CUG triplet repeatsQ34068475
A novel homeodomain-encoding gene is associated with a large CpG island interrupted by the myotonic dystrophy unstable (CTG)n repeatQ34374463
Myotonic dystrophy: molecular windows on a complex etiologyQ34658838
Masking, unmasking, and regulated polyadenylation cooperate in the translational control of a dormant mRNA in mouse oocytesQ35207870
Translational regulation of human p53 gene expression.Q35907084
Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissuesQ36235446
In vivo antisense oligodeoxynucleotide mapping reveals masked regulatory elements in an mRNA dormant in mouse oocytesQ36567386
Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcriptsQ36656342
Detection and characterization of a 3' untranslated region ribonucleoprotein complex associated with human alpha-globin mRNA stabilityQ38298122
Erythroid cell-specific mRNA stability elements in the alpha 2-globin 3' nontranslated regionQ40016165
Disruption of splicing regulated by a CUG-binding protein in myotonic dystrophyQ41041118
Definition of regulatory sequence elements in the promoter region and the first intron of the myotonic dystrophy protein kinase geneQ41043651
Activity of a 40 kDa RNA-binding protein correlates with MYCN and c-fos mRNA stability in human neuroblastomaQ41056115
Trinucleotide repeat expansion at the myotonic dystrophy locus reduces expression of DMAHP.Q41097952
Binding of a 40-kDa protein to the N-myc 3'-untranslated region correlates with enhanced N-myc expression in human neuroblastomaQ41144091
Myotonic dystrophy: Molecular and cellular consequences of expanded DNA repeats are elusiveQ41521385
Messenger RNAs in dendrites: localization, stability, and implications for neuronal functionQ41721619
Expansion of the myotonic dystrophy CTG repeat reduces expression of the flanking DMAHP geneQ48046904
Destabilization of human alpha-globin mRNA by translation anti-termination is controlled during erythroid differentiation and is paralleled by phased shortening of the poly(A) tail.Q52195729
Differential Activity of ELAV-like RNA-binding Proteins in Human NeuroblastomaQ57734337
Impaired On/Off Regulation of TNF Biosynthesis in Mice Lacking TNF AU-Rich ElementsQ62819809
Mice lacking the myotonic dystrophy protein kinase develop a late onset progressive myopathyQ71167717
An expanded CTG trinucleotide repeat causes trans RNA interference: a new hypothesis for the pathogenesis of myotonic dystrophyQ73097983
Constitutive and regulated modes of splicing produce six major myotonic dystrophy protein kinase (DMPK) isoforms with distinct propertiesQ73502630
Simultaneous analysis of expression of the three myotonic dystrophy locus genes in adult skeletal muscle samples: the CTG expansion correlates inversely with DMPK and 59 expression levels, but not DMAHP levelsQ77760274
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectpathologyQ7208
P304page(s)637-641
P577publication date2000-06-01
P1433published inNature MedicineQ1633234
P1476titleThe 3' untranslated region of messenger RNA: A molecular 'hotspot' for pathology?
P478volume6