GLUT-2 function in glucose-unresponsive beta cells of dexamethasone-induced diabetes in rats

scientific article

GLUT-2 function in glucose-unresponsive beta cells of dexamethasone-induced diabetes in rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1172/JCI116788
P932PMC publication ID288361
P698PubMed publication ID8408647
P5875ResearchGate publication ID14789956

P2093author name stringJ H Johnson
M Ohneda
R H Unger
L R Inman
P2860cites workArginine-Stimulated Hyperglucagonemia in Diabetic Pima IndiansQ51671007
31 The in Vitro perfused pancreasQ66898297
Preliminary characterization of calcium binding in islet-cell plasma membranesQ67256261
Enzymic and metabolic anomalies in islets of diabetic rats: relationship to B cell massQ67487939
Expression and function of GLUT-1 and GLUT-2 glucose transporter isoforms in cells of cultured rat pancreatic isletsQ68027472
Possible role of glycogen accumulation in B-cell glucotoxicityQ68228297
Underexpression of beta cell high Km glucose transporters in noninsulin-dependent diabetesQ68598308
Inhibition of glucose transport into rat islet cells by immunoglobulins from patients with new-onset insulin-dependent diabetes mellitusQ68930016
GLUT2 expression and function in beta-cells of GK rats with NIDDM. Dissociation between reductions in glucose transport and glucose-stimulated insulin secretionQ70767520
Coated Charcoal Immunoassay of InsulinQ71162157
Immunoassay of endogenous plasma insulin in manQ22306302
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Glucose stimulates proinsulin biosynthesis by a dose-dependent recruitment of pancreatic beta cellsQ33577735
Regulation of beta-cell glucose transporter gene expressionQ33603742
Reduced expression of the liver/beta-cell glucose transporter isoform in glucose-insensitive pancreatic beta cells of diabetic ratsQ33757675
Interference of glycogenolysis with glycolysis in pancreatic islets from glucose-infused ratsQ33889169
Evidence that down-regulation of beta-cell glucose transporters in non-insulin-dependent diabetes may be the cause of diabetic hyperglycemiaQ33927457
Repeated glucose stimulation reveals distinct and lasting secretion patterns of individual rat pancreatic B cellsQ34265329
Differences in glucose recognition by individual rat pancreatic B cells are associated with intercellular differences in glucose-induced biosynthetic activityQ35596142
The loss of GLUT2 expression by glucose-unresponsive beta cells of db/db mice is reversible and is induced by the diabetic environmentQ35603440
Roles of insulin resistance and beta-cell dysfunction in dexamethasone-induced diabetesQ35605251
Pathogenesis of type 2 (non-insulin dependent) diabetes mellitus: a balanced overviewQ35787142
Arginine-stimulated acute phase of insulin and glucagon secretion in diabetic subjectsQ35903867
Cloning and functional expression in bacteria of a novel glucose transporter present in liver, intestine, kidney, and beta-pancreatic islet cellsQ36427862
Heterogeneous expression of glucokinase among pancreatic beta cellsQ36912605
Loss of insulin response to glucose but not arginine during the development of autoimmune diabetes in BB/W rats: relationships to islet volume and glucose transport rateQ37412738
Diabetic hyperglycemia: link to impaired glucose transport in pancreatic beta cellsQ37671830
Insulin secretion in diabetes mellitusQ40302183
Paradoxical Inhibition of Insulin Secretion by Glucose in Human Diabetes Mellitus*Q41500516
Glucose Insensitivity and Amino-acid Hypersensitivity of Insulin Release in Rats with Non-insulin-dependent Diabetes: A Study with the Perfused PancreasQ42454625
Beta-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetesQ42475849
Perturbation of pancreatic islet function in glucose-infused ratsQ42485912
Transfection of AtT-20ins cells with GLUT-2 but not GLUT-1 confers glucose-stimulated insulin secretion. Relationship to glucose metabolismQ42809256
Localization of the pancreatic beta cell glucose transporter to specific plasma membrane domainsQ43512272
Immunoreactive glucagon (IRG) responses to intravenous glucose in prediabetes and diabetes among Pima Indians and normal CaucasiansQ51023388
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectglycobiologyQ899224
dexamethasoneQ422252
P304page(s)1950-1956
P577publication date1993-10-01
P1433published inJournal of Clinical InvestigationQ3186904
P1476titleGLUT-2 function in glucose-unresponsive beta cells of dexamethasone-induced diabetes in rats
P478volume92

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cites work (P2860)
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Q58088444Dexamethasone Induces Posttranslational Degradation of GLUT2 and Inhibition of Insulin Secretion in Isolated Pancreatic β Cells
Q39777522Direct glucocorticoid inhibition of insulin secretion. An in vitro study of dexamethasone effects in mouse islets
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