| review article | Q7318358 |
| scholarly article | Q13442814 |
| P2093 | author name string | P J Shaw | |
| C J Eggett | |||
| P2860 | cites work | Normal oxidative damage to mitochondrial and nuclear DNA is extensive | Q24649831 |
| Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase | Q27731976 | ||
| Expression of the glial glutamate transporter EAAT2 in the human CNS: an immunohistochemical study | Q28260466 | ||
| Aberrant RNA processing in a neurodegenerative disease: the cause for absent EAAT2, a glutamate transporter, in amyotrophic lateral sclerosis | Q28267385 | ||
| Mutations in the glutamate transporter EAAT2 gene do not cause abnormal EAAT2 transcripts in amyotrophic lateral sclerosis | Q28270636 | ||
| Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells | Q28297730 | ||
| Differential regional distribution of AMPA receptor subunit messenger RNAs in the human spinal cord as visualized by in situ hybridization | Q28298878 | ||
| A mutant neurofilament subunit causes massive, selective motor neuron death: implications for the pathogenesis of human motor neuron disease | Q28511439 | ||
| Cloned glutamate receptors | Q29619950 | ||
| Selective loss of glial glutamate transporter GLT‐1 in amyotrophic lateral sclerosis | Q34300016 | ||
| Superoxide dismutase is an abundant component in cell bodies, dendrites, and axons of motor neurons and in a subset of other neurons | Q34667159 | ||
| Phosphorylation of neurofilaments is altered in amyotrophic lateral sclerosis | Q35110141 | ||
| Glutamate receptor channels: novel properties and new clones | Q35333629 | ||
| Calcium-binding proteins in the nervous system | Q35342133 | ||
| Dementia and aphasia in motor neuron disease: an underrecognised association? | Q36319165 | ||
| Dynamics of neuronal intermediate filaments: a developmental perspective | Q36335012 | ||
| Cytopathology of amyotrophic lateral sclerosis | Q36403979 | ||
| Chronic inhibition of glutamate uptake produces a model of slow neurotoxicity | Q36420529 | ||
| Reappraisal of amyotrophic lateral sclerosis with dementia | Q36812954 | ||
| Relation between cognitive dysfunction and pseudobulbar palsy in amyotrophic lateral sclerosis | Q36905179 | ||
| Transgenic mice carrying a human mutant superoxide dismutase transgene develop neuronal cytoskeletal pathology resembling human amyotrophic lateral sclerosis lesions | Q37688651 | ||
| Excitatory amino acid neurotoxicity and neurodegenerative disease | Q37989602 | ||
| Role of Ca2+ in toxic cell killing | Q38685291 | ||
| Control of proton sensitivity of the NMDA receptor by RNA splicing and polyamines | Q39474796 | ||
| Glutamate becomes neurotoxic via the N-methyl-D-aspartate receptor when intracellular energy levels are reduced | Q39531608 | ||
| Amyotrophic lateral sclerosis and its association with dementia, parkinsonism and other neurological disorders: a review | Q40307172 | ||
| Glutamate receptor update | Q40392909 | ||
| Calcium: still center-stage in hypoxic-ischemic neuronal death | Q40400040 | ||
| Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice | Q40612435 | ||
| Pathological implications of nitric oxide, superoxide and peroxynitrite formation | Q40857191 | ||
| Excitotoxic mechanisms in the pathogenesis of amyotrophic lateral sclerosis. | Q41000773 | ||
| Neurotrophic survival molecules for motoneurons: an embarrassment of riches | Q41089817 | ||
| Selective loss of neurofilament proteins after exposure of differentiated human IMR-32 neuroblastoma cells to oxidative stress | Q41157210 | ||
| Familial amyotrophic lateral sclerosis with a mutation in exon 4 of the Cu/Zn superoxide dismutase gene: pathological and immunocytochemical changes | Q41187994 | ||
| Excitotoxicity in ALS. | Q41263065 | ||
| A role for Na+-dependent Ca2+ extrusion in protection against neuronal excitotoxicity | Q41277707 | ||
| The role of calcium-binding proteins in selective motoneuron vulnerability in amyotrophic lateral sclerosis | Q41413618 | ||
| Glutamate, excitotoxicity and amyotrophic lateral sclerosis | Q41493319 | ||
| The GluR2 (GluR-B) hypothesis: Ca(2+)-permeable AMPA receptors in neurological disorders | Q41623979 | ||
| Divalent ion permeability of AMPA receptor channels is dominated by the edited form of a single subunit | Q41649334 | ||
| Selective and asymmetric vulnerability of corticospinal and spinocerebellar tracts in motor neuron disease | Q41888493 | ||
| Ventral root depolarization and spinal reflex augmentation by a TRH analog in rat spinal cord | Q42258310 | ||
| ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions. | Q46135324 | ||
| In vitro kainate injury to large, SMI-32(+) spinal neurons is Ca2+ dependent. | Q46238488 | ||
| Age-dependent penetrance of disease in a transgenic mouse model of familial amyotrophic lateral sclerosis | Q46310473 | ||
| Cloning of a putative glutamate receptor: a low affinity kainate-binding subunit | Q46554974 | ||
| Corelease of two fast neurotransmitters at a central synapse. | Q47837764 | ||
| Intracellular calcium parallels motoneuron degeneration in SOD-1 mutant mice. | Q47964100 | ||
| Light and electron microscopic distribution of the AMPA receptor subunit, GluR2, in the spinal cord of control and G86R mutant superoxide dismutase transgenic mice | Q47996542 | ||
| Calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptors: a molecular determinant of selective vulnerability in amyotrophic lateral sclerosis | Q48046641 | ||
| Accumulation of phosphorylated neurofilaments in anterior horn motoneurons of amyotrophic lateral sclerosis patients | Q48135713 | ||
| N-methyl-D-aspartate (NMDA) receptors in the spinal cord and motor cortex in motor neuron disease: a quantitative autoradiographic study using [3H]MK-801. | Q48173393 | ||
| Parvalbumin and calbindin D-28k in the human motor system and in motor neuron disease | Q48241885 | ||
| Localization of N-acetylaspartylglutamate-like immunoreactivity in selected areas of the rat brain | Q48265899 | ||
| Do defecs in mitochondrial energy metabolism underlie the pathology of neurodegenerative diseases? | Q48317832 | ||
| Amyotrophic lateral sclerosis associated with genetic abnormalities in the gene encoding Cu/Zn superoxide dismutase: molecular pathology of five new cases, and comparison with previous reports and 73 sporadic cases of ALS. | Q48368353 | ||
| The expression of the glial glutamate transporter protein EAAT2 in motor neuron disease: an immunohistochemical study. | Q48378456 | ||
| Determinants of neuronal vulnerability in neurodegenerative diseases. | Q48389474 | ||
| High sensitivity of glutamate uptake to extracellular free arachidonic acid levels in rat cortical synaptosomes and astrocytes | Q48446997 | ||
| Identification of alternative splicing forms of GLT-1 mRNA in the spinal cord of amyotrophic lateral sclerosis patients | Q48466261 | ||
| Glutamate uptake is decreased tardively in the spinal cord of FALS mice | Q48474166 | ||
| The quantitative autoradiographic distribution of [3H]MK-801 binding sites in the normal human brainstem in relation to motor neuron disease | Q48528440 | ||
| Superoxide dismutase catalyzes nitration of tyrosines by peroxynitrite in the rod and head domains of neurofilament-L. | Q48543872 | ||
| Cytochrome c oxidase subunit I microdeletion in a patient with motor neuron disease. | Q48550765 | ||
| Expression of glutamate receptor subunits in alpha-motoneurons | Q48550980 | ||
| Identification of a site in glutamate receptor subunits that controls calcium permeability | Q48669947 | ||
| Monosodium Glutamate Effects | Q48829030 | ||
| Amyotrophic lateral sclerosis: oxidative energy metabolism and calcium homeostasis in peripheral blood lymphocytes | Q48910244 | ||
| Nonverbal visual attention, but not recognition memory of learning, processes are impaired in motor neurone disease. | Q52048119 | ||
| Quantitative and qualitative changes in AMPA receptor expression during spinal cord development | Q52206809 | ||
| SOD1 mutation is associated with accumulation of neurofilaments in amyotrophic lateral sclerosis. | Q52518692 | ||
| An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria | Q54965159 | ||
| Glutamate potentiates the toxicity of mutant Cu/Zn-superoxide dismutase in motor neurons by postsynaptic calcium-dependent mechanisms | Q57042709 | ||
| Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS | Q57042894 | ||
| Immunocytochemical study of the distribution of the free radical scavenging enzymes CU/ZN superoxide dismutase (SOD1); MN superoxide dismutase (MN SOD) and catalase in the normal human spinal cord and in motor neuron disease | Q59544362 | ||
| Distribution of AMPA-selective glutamate receptor subunits in the human hippocampus and cerebellum | Q59544367 | ||
| Non-NMDA receptors in motor neuron disease (MND): a quantitative autoradiographic study in spinal cord and motor cortex using [3H]CNQX and [3H]kainate | Q59544377 | ||
| Novel insertion in the KSP region of the neurofilament heavy gene in amyotrophic lateral sclerosis (ALS) | Q61955095 | ||
| Phosphorylated high molecular weight neurofilament protein in lower motor neurons in amyotrophic lateral sclerosis and other neurodegenerative diseases involving ventral horn cells | Q67290641 | ||
| Abnormal distribution of phosphorylated neurofilaments in neuronal degeneration induced by kainic acid | Q67691968 | ||
| Action of 5-hydroxytryptamine, substance P, thyrotropin-releasing hormone and clonidine on motoneurone excitability | Q69009759 | ||
| Immunocytochemical and ultrastructural study of Lewy body-like hyaline inclusions in familial amyotrophic lateral sclerosis | Q69085749 | ||
| Cytoskeletal abnormalities in motor neuron disease. An immunocytochemical study | Q69585716 | ||
| Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease | Q70633175 | ||
| Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis | Q70633178 | ||
| Glutamate transporter gene expression in amyotrophic lateral sclerosis motor cortex | Q71053694 | ||
| Protective effect of riluzole on excitatory amino acid-mediated neurotoxicity in motoneuron-enriched cultures | Q71583358 | ||
| Decreased cytochrome c oxidase activity but unchanged superoxide dismutase and glutathione peroxidase activities in the spinal cords of patients with amyotrophic lateral sclerosis | Q71616123 | ||
| Quantitative immunocytochemical analysis of the spinal cord in G86R superoxide dismutase transgenic mice: neurochemical correlates of selective vulnerability | Q71722916 | ||
| Variants of the heavy neurofilament subunit are associated with the development of amyotrophic lateral sclerosis | Q72529952 | ||
| The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray | Q72640800 | ||
| Glycine receptor: light microscopic autoradiographic localization with [3H]strychnine | Q72941178 | ||
| Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1 | Q74454204 | ||
| Low expression of GluR2 AMPA receptor subunit protein by human motor neurons | Q77324803 | ||
| P921 | main subject | amyotrophic lateral sclerosis | Q206901 |
| neurodegeneration | Q1755122 | ||
| P304 | page(s) | I17-27 | |
| P577 | publication date | 2000-03-01 | |
| P1433 | published in | Journal of Neurology | Q6295649 |
| P1476 | title | Molecular factors underlying selective vulnerability of motor neurons to neurodegeneration in amyotrophic lateral sclerosis | |
| P478 | volume | 247 Suppl 1 |
| Q26775401 | A comprehensive review of amyotrophic lateral sclerosis |
| Q37712624 | ALS Pathogenesis and Therapeutic Approaches: The Role of Mesenchymal Stem Cells and Extracellular Vesicles |
| Q37400451 | ALS and oxidative stress: the neurovascular scenario |
| Q90227531 | Acute neurotoxicant exposure induces hyperexcitability in mouse lumbar spinal motor neurons |
| Q35791339 | Alterations in G(1) to S phase cell-cycle regulators during amyotrophic lateral sclerosis |
| Q45713210 | Blocked gap junctional coupling increases glutamate-induced neurotoxicity in neuron-astrocyte co-cultures |
| Q28084373 | Calcium dysregulation links ALS defective proteins and motor neuron selective vulnerability |
| Q41955617 | Calcium ions promote superoxide dismutase 1 (SOD1) aggregation into non-fibrillar amyloid: a link to toxic effects of calcium overload in amyotrophic lateral sclerosis (ALS)? |
| Q34241641 | Cellular stress/the unfolded protein response: relevance to sleep and sleep disorders |
| Q37685252 | Chronic intermittent hypoxia affects endogenous serotonergic inputs and expression of synaptic proteins in rat hypoglossal nucleus |
| Q30667587 | Coculture of Primary Motor Neurons and Schwann Cells as a Model for In Vitro Myelination. |
| Q47907429 | DREAM-Dependent Activation of Astrocytes in Amyotrophic Lateral Sclerosis. |
| Q35933131 | Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo |
| Q90231693 | Deregulated miR-29b-3p Correlates with Tissue-Specific Activation of Intrinsic Apoptosis in An Animal Model of Amyotrophic Lateral Sclerosis |
| Q42455189 | Differential expression of transcription factors and inflammation-, ROS-, and cell death-related genes in organotypic cultures in the modiolus, the organ of Corti and the stria vascularis of newborn rats |
| Q45014653 | Differential expression of voltage-activated calcium channels in III and XII motoneurones during development in the rat. |
| Q36012034 | Dysregulated expression of death, stress and mitochondrion related genes in the sciatic nerve of presymptomatic SOD1(G93A) mouse model of Amyotrophic Lateral Sclerosis |
| Q46729669 | Eif-2a protects brainstem motoneurons in a murine model of sleep apnea |
| Q52651163 | Energy metabolism in ALS: an underappreciated opportunity? |
| Q34538330 | Glial cell inclusions and the pathogenesis of neurodegenerative diseases |
| Q34550482 | Glial proliferation and metabotropic glutamate receptor expression in amyotrophic lateral sclerosis. |
| Q36565671 | Implications for the kynurenine pathway and quinolinic acid in amyotrophic lateral sclerosis. |
| Q34122546 | Inhibition of West Nile virus by calbindin-D28k |
| Q36934383 | Intraperitoneally administered IgG from patients with amyotrophic lateral sclerosis or from an immune-mediated goat model increase the levels of TNF-α, IL-6, and IL-10 in the spinal cord and serum of mice. |
| Q37143580 | Ionotropic glutamate receptors & CNS disorders. |
| Q42121950 | Linking selective vulnerability to cell death mechanisms in Parkinson's disease |
| Q28365454 | Mechanisms of neurodegeneration in amyotrophic lateral sclerosis |
| Q39101800 | Metabolic Dysfunctions in Amyotrophic Lateral Sclerosis Pathogenesis and Potential Metabolic Treatments |
| Q45001313 | Mitochondrial oxidative phosphorylation transcriptome alterations in human amyotrophic lateral sclerosis spinal cord and blood |
| Q35489359 | Molecular and cellular pathways of neurodegeneration in motor neurone disease |
| Q37952528 | Molecular pathways of motor neuron injury in amyotrophic lateral sclerosis |
| Q35577690 | Motoneuron subtypes show specificity in glycine receptor channel abnormalities in a transgenic mouse model of amyotrophic lateral sclerosis |
| Q33600152 | Motor neurone disease. |
| Q35111080 | Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models. |
| Q37073851 | Nutrition and dietary supplements in motor neuron disease |
| Q50436779 | Optimized methods for rapidly dissecting spinal cords and harvesting spinal motor neurons with high survival and purity from rats at different embryonic stages |
| Q61804436 | Oxidative stress: the lowest common denominator of multiple diseases |
| Q35182047 | Prospects for the pharmacotherapy of amyotrophic lateral sclerosis : old strategies and new paradigms for the third millennium |
| Q43840174 | Protective activity of aromatic amines and imines against oxidative nerve cell death |
| Q58711477 | Real-time visualization of oxidative stress-mediated neurodegeneration of individual spinal motor neurons in vivo |
| Q48467177 | Region-specific changes in the immunoreactivity of TRPV4 expression in the central nervous system of SOD1(G93A) transgenic mice as an in vivo model of amyotrophic lateral sclerosis |
| Q42472658 | Regulation of glutamate transporters in astrocytes: evidence for a relationship between transporter expression and astrocytic phenotype |
| Q38004940 | Roles of endoplasmic reticulum and energetic stress in disturbed sleep |
| Q33776847 | SOD1, an unexpected novel target for cancer therapy |
| Q44658133 | Selective modifications in GAD67 mRNA levels in striatonigral and striatopallidal pathways correlate to dopamine agonist priming in 6-hydroxydopamine-lesioned rats. |
| Q33868370 | Selective neuronal vulnerability to oxidative stress in the brain |
| Q91705233 | Selective vulnerability in neurodegenerative diseases |
| Q28082279 | Spreading of pathology in neurodegenerative diseases: a focus on human studies |
| Q26995278 | Stem cell transplantation for motor neuron disease: current approaches and future perspectives |
| Q90295506 | The basis of clinicopathological heterogeneity in TDP-43 proteinopathy |
| Q28263899 | The complex molecular biology of amyotrophic lateral sclerosis (ALS) |
| Q44269706 | The oxidant defense system in human neuroblastoma IMR-32 cells predifferentiation and postdifferentiation to neuronal phenotypes |
| Q34080374 | Time Course Analysis of Gene Expression Patterns in Zebrafish Eye During Optic Nerve Regeneration |
| Q35919917 | Vascular endothelial growth factor and the nervous system. |
| Q41842390 | Voltage-gated calcium channels are abnormal in cultured spinal motoneurons in the G93A-SOD1 transgenic mouse model of ALS. |
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