scholarly article | Q13442814 |
P819 | ADS bibcode | 2016NatCo...711350Z |
P6179 | Dimensions Publication ID | 1004802467 |
P356 | DOI | 10.1038/NCOMMS11350 |
P8608 | Fatcat ID | release_vk2qormoezg77osxfx6daw6wrm |
P932 | PMC publication ID | 5512610 |
P698 | PubMed publication ID | 27072778 |
P50 | author | Jennifer S Nelson | Q86882118 |
Joshua Starmer | Q104197052 | ||
Maureen A Su | Q42722308 | ||
P2093 | author name string | Elizabeth M Wilson | |
Aaron Martin | |||
Bridget Conley | |||
Meghan Free | |||
Meng-Lei Zhu | |||
Pearl Bakhru | |||
P2860 | cites work | Sex ratio of multiple sclerosis in Canada: a longitudinal study. | Q51779582 |
The insulin gene is transcribed in the human thymus and transcription levels correlated with allelic variation at the INS VNTR-IDDM2 susceptibility locus for type 1 diabetes. | Q52196097 | ||
Sex differences in the gut microbiome drive hormone-dependent regulation of autoimmunity. | Q54468190 | ||
Fezf2 Orchestrates a Thymic Program of Self-Antigen Expression for Immune Tolerance. | Q55059402 | ||
Androgen depletion increases the efficacy of bone marrow transplantation in ameliorating experimental autoimmune encephalomyelitis | Q62078499 | ||
Testosterone induces expression of transforming growth factor-beta 1 in the murine thymus | Q70731000 | ||
Simultaneous postnatal rise of plasma LH and testosterone in male infants | Q71334238 | ||
Mechanism of androgen-induced thymolysis in rats | Q71813017 | ||
Insulin expression levels in the thymus modulate insulin-specific autoreactive T-cell tolerance: the mechanism by which the IDDM2 locus may predispose to diabetes | Q78014697 | ||
Ets transcription factors regulate AIRE gene promoter | Q80062954 | ||
Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice | Q81377810 | ||
Experimental autoimmune encephalomyelitis in the mouse | Q82837777 | ||
TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions | Q21999527 | ||
PDEF, a novel prostate epithelium-specific ets transcription factor, interacts with the androgen receptor and activates prostate-specific antigen gene expression | Q22011032 | ||
Aire's partners in the molecular control of immunological tolerance | Q24296286 | ||
Aire and T cell development | Q24621103 | ||
Tumor-specific Th17-polarized cells eradicate large established melanoma | Q24648032 | ||
Deletional tolerance mediated by extrathymic Aire-expressing cells | Q24652952 | ||
edgeR: a Bioconductor package for differential expression analysis of digital gene expression data | Q27860819 | ||
Positional cloning of the APECED gene | Q28116470 | ||
Projection of an immunological self shadow within the thymus by the aire protein | Q28207164 | ||
Trimmomatic: a flexible trimmer for Illumina sequence data | Q29547278 | ||
HTSeq--a Python framework to work with high-throughput sequencing data | Q29614489 | ||
Transplantation of autoimmune regulator-encoding bone marrow cells delays the onset of experimental autoimmune encephalomyelitis | Q39627505 | ||
Time-dependent rescue of gene expression by androgens in the mouse proximal caput epididymidis-1 cell line after androgen withdrawal | Q40223151 | ||
Androgen receptor signaling: mechanism of interleukin-6 inhibition. | Q40570918 | ||
Lymphotoxin pathway directs thymic Aire expression | Q40630236 | ||
Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution | Q42780735 | ||
Androgens indirectly accelerate thymocyte apoptosis | Q43613360 | ||
Androgens are protective in experimental autoimmune encephalomyelitis: implications for multiple sclerosis. | Q44708828 | ||
Androgen deprivation induces phenotypic and functional changes in the thymus of adult male mice | Q45088217 | ||
Gonadotropin-Releasing Hormone Antagonists: Novel Members of the Azaline B Family | Q46745475 | ||
Age and sex associations of 40 autoimmune diseases | Q47306926 | ||
Antiinflammatory effect of androgen receptor activation in human benign prostatic hyperplasia cells | Q47802044 | ||
The human androgen receptor: complementary deoxyribonucleic acid cloning, sequence analysis and gene expression in prostate | Q48309646 | ||
Longitudinal reproductive hormone profiles in infants: peak of inhibin B levels in infant boys exceeds levels in adult men. | Q50907940 | ||
Androgens accelerate thymocyte apoptosis. | Q50910612 | ||
Androgen receptors in thymic epithelium modulate thymus size and thymocyte development | Q31957984 | ||
Naive tumor-specific CD4(+) T cells differentiated in vivo eradicate established melanoma. | Q33730129 | ||
Tumor-reactive CD4(+) T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts | Q33730171 | ||
Gender differences in autoimmune disease | Q34040802 | ||
Melanoma antigen-A11 (MAGE-A11) enhances transcriptional activity by linking androgen receptor dimers | Q34313140 | ||
Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development | Q34577749 | ||
An IRF8-binding promoter variant and AIRE control CHRNA1 promiscuous expression in thymus | Q34581770 | ||
Population and single-cell genomics reveal the Aire dependency, relief from Polycomb silencing, and distribution of self-antigen expression in thymic epithelia | Q34590391 | ||
Testosterone treatment in multiple sclerosis: a pilot study | Q34628272 | ||
Evidence that androgens modulate human thymic T cell output. | Q34796229 | ||
Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression | Q34831296 | ||
Sex hormones have pervasive effects on thymic epithelial cells. | Q35926133 | ||
Progesterone and autoimmune disease | Q36202227 | ||
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen | Q36228141 | ||
Proliferative arrest and rapid turnover of thymic epithelial cells expressing Aire | Q36229072 | ||
Identification of a novel cis-regulatory element essential for immune tolerance | Q36286062 | ||
Gene dosage--limiting role of Aire in thymic expression, clonal deletion, and organ-specific autoimmunity. | Q36399327 | ||
Mechanisms of an autoimmunity syndrome in mice caused by a dominant mutation in Aire | Q36540892 | ||
Keratinocyte growth factor and androgen blockade work in concert to protect against conditioning regimen-induced thymic epithelial damage and enhance T-cell reconstitution after murine bone marrow transplantation | Q36713565 | ||
Aire deficiency promotes TRP-1-specific immune rejection of melanoma | Q36745323 | ||
Aire-dependent thymic development of tumor-associated regulatory T cells | Q36754190 | ||
The ETS domain transcription factor ELK1 directs a critical component of growth signaling by the androgen receptor in prostate cancer cells | Q36779605 | ||
Immune modulation and increased neurotrophic factor production in multiple sclerosis patients treated with testosterone | Q36841506 | ||
The complex role of estrogens in inflammation. | Q36886660 | ||
Neonatal tolerance revisited: a perinatal window for Aire control of autoimmunity | Q37273185 | ||
Gender bias in autoimmunity is influenced by microbiota. | Q37294725 | ||
Systems analysis of sex differences reveals an immunosuppressive role for testosterone in the response to influenza vaccination | Q37495044 | ||
An RNAi screen for Aire cofactors reveals a role for Hnrnpl in polymerase release and Aire-activated ectopic transcription | Q37544045 | ||
The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation | Q37583514 | ||
The transcriptional regulator Aire coopts the repressive ATF7ip-MBD1 complex for the induction of immunotolerance. | Q38309456 | ||
Identification and characterization of androgen response elements | Q38333067 | ||
Characterization of regulatory elements and methylation pattern of the autoimmune regulator (AIRE) promoter | Q38356484 | ||
The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population | Q39556141 | ||
P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
P6216 | copyright status | copyrighted | Q50423863 |
P407 | language of work or name | English | Q1860 |
P921 | main subject | bias | Q742736 |
gender bias | Q1501326 | ||
autoimmune disease | Q8084905 | ||
P304 | page(s) | 11350 | |
P577 | publication date | 2016-04-13 | |
P1433 | published in | Nature Communications | Q573880 |
P1476 | title | Sex bias in CNS autoimmune disease mediated by androgen control of autoimmune regulator | |
P478 | volume | 7 |
Q52769615 | A vestigial pathway for sex differences in immune regulation. |
Q55417295 | AIRE promotes androgen-independent prostate cancer by directly regulating IL-6 and modulating tumor microenvironment. |
Q47227251 | AIRE: a missing link to explain female susceptibility to autoimmune diseases. |
Q50050062 | Activating transcription factor 6α deficiency exacerbates oligodendrocyte death and myelin damage in immune-mediated demyelinating diseases |
Q64095333 | Age-related Autoimmune Changes in Lacrimal Glands |
Q92459022 | An Inconvenient Variable: Sex Hormones and Their Impact on T Cell Responses |
Q55357541 | Androgen-Induced Immunosuppression. |
Q57800002 | Androgen-dependent immune modulation in parasitic infection |
Q38665189 | Androgen-mediated sex bias impairs efficiency of leukotriene biosynthesis inhibitors in males |
Q104134890 | B7-CD28 co-stimulation modulates central tolerance via thymic clonal deletion and Treg generation through distinct mechanisms |
Q41368509 | Balance between Estrogens and Proinflammatory Cytokines Regulates Chemokine Production Involved in Thymic Germinal Center Formation |
Q96302822 | Considering how biological sex impacts immune responses and COVID-19 outcomes |
Q92846950 | Cross-disorder analysis of schizophrenia and 19 immune-mediated diseases identifies shared genetic risk |
Q36737869 | Estrogen turns down "the AIRE" |
Q36262581 | IL-27 Limits Type 2 Immunopathology Following Parainfluenza Virus Infection. |
Q89493861 | Immune System Sex Differences May Bridge the Gap Between Sex and Gender in Fibromyalgia |
Q97883534 | Impact of Androgens on Inflammation-Related Lipid Mediator Biosynthesis in Innate Immune Cells |
Q97883479 | Influence of Androgens on Immunity to Self and Foreign: Effects on Immunity and Cancer |
Q89467795 | Involvement of Claudin-11 in Disruption of Blood-Brain, -Spinal Cord, and -Arachnoid Barriers in Multiple Sclerosis |
Q58769130 | Minipuberty and Sexual Dimorphism in the Infant Human Thymus |
Q90573900 | Regulatory T Cell Development in the Thymus |
Q50026558 | Sex bias in MHC I-associated shaping of the adaptive immune system. |
Q58549463 | Sex bias in autoimmunity |
Q64272829 | Testosterone Influence on Gene Expression in Lacrimal Glands of Mouse Models of Sjögren Syndrome |
Q98735476 | The Effects of Androgens on T Cells: Clues to Female Predominance in Autoimmune Liver Diseases? |
Q39386100 | The multiple pathways to autoimmunity |
Q102060892 | The role of sex hormones in women with Multiple Sclerosis: from puberty to assisted reproductive techniques |
Q50314118 | Twenty Years of AIRE. |
Q49200196 | Type 1 Diabetes: A Chronic Anti-Self-Inflammatory Response |
Q47856335 | Update on Aire and thymic negative selection |
Q91643417 | Updated advances of linking psychosocial factors and sex hormones with systemic lupus erythematosus susceptibility and development |
Q52712155 | [Autoimmune disease predisposition: Aire « protects » men]. |
Search more.