Overexpression of angiotensin-converting enzyme 2 attenuates tonically active glutamatergic input to the rostral ventrolateral medulla in hypertensive rats

scientific article

Overexpression of angiotensin-converting enzyme 2 attenuates tonically active glutamatergic input to the rostral ventrolateral medulla in hypertensive rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPHEART.00518.2013
P932PMC publication ID4101646
P698PubMed publication ID24838502
P5875ResearchGate publication ID262420919

P2093author name stringQiang Yu
Qiang Hao
Yu Deng
Wei-Zhong Wang
Ding-Feng Su
Wen-Jun Yuan
Zhao-Tang Wu
Qi-Kuan Hu
Yang-Kai Wang
Du Shen
Yan-Fang Chen
P2860cites workAngiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulationQ24311938
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Angiotensin-converting enzyme 2 as a novel target for gene therapy for hypertensionQ28301752
The sympathetic control of blood pressureQ30440682
Tonic excitatory input to the rostral ventrolateral medulla in Dahl salt-sensitive ratsQ32069498
Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertensionQ33639490
Localization and function of angiotensin AT1 receptorsQ33839720
Chronic AT1 receptor blockade normalizes NMDA-mediated changes in renal sympathetic nerve activity and NR1 expression within the PVN in rats with heart failureQ33840765
Exercise training prevents the exaggerated exercise pressor reflex in rats with chronic heart failureQ33841212
What drives the tonic activity of presympathetic neurons in the rostral ventrolateral medulla?Q34105056
Role of excitatory amino acid inputs to the rostral ventrolateral medulla in cardiovascular regulationQ34636715
ACE2/ANG-(1-7)/Mas pathway in the brain: the axis of good.Q34784864
Angiotensin-converting enzyme 2: central regulator for cardiovascular functionQ34978620
Presynaptic calcium influx, neurotransmitter release, and neuromuscular diseaseQ35044631
Central angiotensin (1-7) enhances baroreflex gain in conscious rabbits with heart failureQ35278101
Differential expression of neuronal ACE2 in transgenic mice with overexpression of the brain renin-angiotensin systemQ35567432
ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertensionQ35776364
ACE2: A novel therapeutic target for cardiovascular diseasesQ36189805
Tonic glutamatergic input in the rostral ventrolateral medulla is increased in rats with chronic heart failureQ36615795
Cardiovascular effects of angiotensin II in the rostral ventrolateral medulla: the push-pull hypothesisQ36829027
ALDH2 protects against stroke by clearing 4-HNE.Q36973943
Angiotensin-converting enzyme 2 in the brain: properties and future directionsQ37155907
PACAP causes PAC1/VPAC2 receptor mediated hypertension and sympathoexcitation in normal and hypertensive rats.Q37174587
COX-1-derived PGE2 and PGE2 type 1 receptors are vital for angiotensin II-induced formation of reactive oxygen species and Ca(2+) influx in the subfornical organQ37342150
Angiotensin (1-7) contributes to nitric oxide tonic inhibition of vasopressin release during hemorrhagic shock in acute ethanol intoxicated rodentsQ37347019
Brain angiotensin peptides regulate sympathetic tone and blood pressureQ37760775
Efficient large-scale production and concentration of HIV-1-based lentiviral vectors for use in vivoQ40682749
Functional organization of central pathways regulating the cardiovascular systemQ40746768
Renin-Angiotensin system hyperactivation can induce inflammation and retinal neural dysfunctionQ42098043
Role of angiotensin-(1-7) in amino-acid-neurotransmitter-mediated blood pressure regulation in rat rostral ventrolateral medullaQ43609077
Differential role of kinases in brain stem of hypertensive and normotensive ratsQ43801309
Ventrolateral medulla AT1 receptors support arterial pressure in Dahl salt-sensitive ratsQ44353836
Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition.Q44495463
ANG II-induced excitation of paraventricular nucleus magnocellular neurons: a role for glutamate interneuronsQ44730536
Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive ratsQ45069630
Unique levels of expression of N-methyl-D-aspartate receptor subunits and neuronal nitric oxide synthase in the rostral ventrolateral medulla of the spontaneously hypertensive rat.Q45094604
GABAergic mechanism in the rostral ventrolateral medulla contributes to the hypotension of moxonidineQ45166972
Sympathoinhibitory mechanism of moxonidine: role of the inducible nitric oxide synthase in the rostral ventrolateral medulla.Q45965057
In vivo characterization of the angiotensin-(1-7)-induced dopamine and gamma-aminobutyric acid release in the striatum of the rat.Q46651527
Chronic infusion of angiotensin-(1-7) into the lateral ventricle of the brain attenuates hypertension in DOCA-salt ratsQ47668496
Angiotensin II-induced calcium signalling in neurons and astrocytes of rat circumventricular organsQ47987387
Exercise training lowers the enhanced tonically active glutamatergic input to the rostral ventrolateral medulla in hypertensive ratsQ48114244
Contribution of AMPA/kainate receptors in the rostral ventrolateral medulla to the hypotensive and sympathoinhibitory effects of clonidineQ48130948
Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive ratsQ48260358
Ventrolateral medulla in spontaneously hypertensive rats: role of angiotensin II.Q48336826
Antihypertensive treatment and the responsiveness to glutamate in ventrolateral medullaQ48552324
Central amino acids mediate cardiovascular response to angiotensin II in the rat.Q48555201
Tonic glutamate-mediated control of rostral ventrolateral medulla and sympathetic vasomotor toneQ48647265
Angiotensin type 1A receptors in C1 neurons of the rostral ventrolateral medulla modulate the pressor response to aversive stressQ48666015
Oxidative stress in the rostral ventrolateral medulla modulates excitatory and inhibitory inputs in spontaneously hypertensive ratsQ48788047
Excitatory amino acids in the rostral ventrolateral medulla support blood pressure in spontaneously hypertensive rats.Q52537768
Genetically altered brain amino acid metabolism in spontaneously hypertensive rats: a study by using young spontaneously hypertensive rats and renal hypertensive ratsQ68630297
Cardiovascular effects of NMDA in the RVLM of spontaneously hypertensive ratsQ71938531
Nitric oxide reduces depolarization-induced calcium influx in PC12 cells by a cyclic GMP-mediated mechanismQ72071708
Losartan, nonpeptide angiotensin II-type 1 (AT1) receptor antagonist, attenuates pressor and sympathoexcitatory responses evoked by angiotensin II and L-glutamate in rostral ventrolateral medullaQ72641587
Nitric oxide reduces Ca(2+) and Zn(2+) influx through voltage-gated Ca(2+) channels and reduces Zn(2+) neurotoxicityQ73247411
P433issue2
P921main subjectoverexpressionQ61643320
P304page(s)H182-90
P577publication date2014-05-16
P1433published inAmerican Journal of Physiology Heart and Circulatory PhysiologyQ3193662
P1476titleOverexpression of angiotensin-converting enzyme 2 attenuates tonically active glutamatergic input to the rostral ventrolateral medulla in hypertensive rats
P478volume307

Reverse relations

cites work (P2860)
Q57464926Angiotensin-Converting Enzyme 2 in the Rostral Ventrolateral Medulla Regulates Cholinergic Signaling and Cardiovascular and Sympathetic Responses in Hypertensive Rats
Q33648557Angiotensin-converting enzyme 2 overexpression protects against doxorubicin-induced cardiomyopathy by multiple mechanisms in rats
Q37005635Angiotensin-converting enzyme 2 prevents lipopolysaccharide-induced rat acute lung injury via suppressing the ERK1/2 and NF-κB signaling pathways
Q47215283Brain-Specific SNAP-25 Deletion Leads to Elevated Extracellular Glutamate Level and Schizophrenia-Like Behavior in Mice
Q50072075Development of obesity can be prevented in rats by chronic icv infusions of AngII but less by Ang(1-7).
Q47131988Enhancement in Tonically Active Glutamatergic Inputs to the Rostral Ventrolateral Medulla Contributes to Neuropathic Pain-Induced High Blood Pressure.
Q36310427Estrogen Replacement Reduces Oxidative Stress in the Rostral Ventrolateral Medulla of Ovariectomized Rats
Q36530437Exercise Training Improves the Altered Renin-Angiotensin System in the Rostral Ventrolateral Medulla of Hypertensive Rats
Q53279466Overexpression of ß-Arrestin1 in the Rostral Ventrolateral Medulla Downregulates Angiotensin Receptor and Lowers Blood Pressure in Hypertension.
Q46269748The Cardiovascular Effect of Systemic Homocysteine Is Associated with Oxidative Stress in the Rostral Ventrolateral Medulla.
Q48248287The phosphoinositide-3 kinase signaling is involved in neuroinflammation in hypertensive rats.

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