| scholarly article | Q13442814 |
| P356 | DOI | 10.1074/JBC.M007558200 |
| P698 | PubMed publication ID | 11092882 |
| P2093 | author name string | Patel MS | |
| Korotchkina LG | |||
| P2860 | cites work | Function of the nonidentical subunits of mammalian pyruvate dehydrogenase | Q54191818 |
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| The elementary reactions of the pig heart pyruvate dehydrogenase complex. A study of the inhibition by phosphorylation | Q40013517 | ||
| Binding of thiamin thiazolone pyrophosphate to mammalian pyruvate dehydrogenase and its effects on kinase and phosphatase activities | Q40055931 | ||
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| Occupancy of phosphorylation sites in pyruvate dehydrogenase phosphate complex in rat heart in vivo. Relation to proportion of inactive complex and rate of re-activation by phosphatase | Q42875241 | ||
| Organization and functioning of muscle pyruvate dehydrogenase active centers | Q43638159 | ||
| Electrostatic and steric contributions to regulation at the active site of isocitrate dehydrogenase | Q46419493 | ||
| Systemic deficiency of the first component of the pyruvate dehydrogenase complex | Q48215817 | ||
| A general method for rapid site-directed mutagenesis using the polymerase chain reaction. | Q48247178 | ||
| Expression of pyruvate dehydrogenase isoforms during the aerobic/anaerobic transition in the development of the parasitic nematode Ascaris suum: altered stoichiometry of phosphorylation/inactivation. | Q52187805 | ||
| P433 | issue | 8 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | phosphorylation | Q242736 |
| P304 | page(s) | 5731-5738 | |
| P577 | publication date | 2000-11-22 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Probing the mechanism of inactivation of human pyruvate dehydrogenase by phosphorylation of three sites | |
| P478 | volume | 276 |
| Q39030297 | A phase I open-labeled, single-arm, dose-escalation, study of dichloroacetate (DCA) in patients with advanced solid tumors. |
| Q35613519 | Acetylphosphinate is the most potent mechanism-based substrate-like inhibitor of both the human and Escherichia coli pyruvate dehydrogenase components of the pyruvate dehydrogenase complex |
| Q28189278 | Activation and mitochondrial translocation of protein kinase Cdelta are necessary for insulin stimulation of pyruvate dehydrogenase complex activity in muscle and liver cells |
| Q34557385 | Asp295 stabilizes the active-site loop structure of pyruvate dehydrogenase, facilitating phosphorylation of ser292 by pyruvate dehydrogenase-kinase |
| Q24307378 | Binding of pyruvate dehydrogenase to the core of the human pyruvate dehydrogenase complex |
| Q60304738 | Characterization of Mycoplasma gallisepticum pyruvate dehydrogenase alpha and beta subunits and their roles in cytoadherence |
| Q43847673 | Characterization of a missense mutation at histidine-44 in a pyruvate dehydrogenase-deficient patient |
| Q24302051 | Characterization of testis-specific isoenzyme of human pyruvate dehydrogenase |
| Q36854802 | Competence of Thiamin Diphosphate-Dependent Enzymes with 2'-Methoxythiamin Diphosphate Derived from Bacimethrin, a Naturally Occurring Thiamin Anti-vitamin |
| Q64081998 | Conserved phosphorylation hotspots in eukaryotic protein domain families |
| Q51892557 | Developmental regulation of mitochondrial biogenesis and function in the mouse mammary gland during a prolonged lactation cycle. |
| Q36001522 | Differential inhibition of PDKs by phenylbutyrate and enhancement of pyruvate dehydrogenase complex activity by combination with dichloroacetate |
| Q24336876 | Distinct structural mechanisms for inhibition of pyruvate dehydrogenase kinase isoforms by AZD7545, dichloroacetate, and radicicol |
| Q28251109 | Down-regulation of pyruvate dehydrogenase phosphatase in obese subjects is a defect that signals insulin resistance |
| Q34972253 | Elucidation of the interaction loci of the human pyruvate dehydrogenase complex E2·E3BP core with pyruvate dehydrogenase kinase 1 and kinase 2 by H/D exchange mass spectrometry and nuclear magnetic resonance |
| Q56240297 | Exercise-induced pyruvate dehydrogenase activation is not affected by 7 days of bed rest |
| Q42656697 | Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components |
| Q41358539 | Furoates and thenoates inhibit pyruvate dehydrogenase kinase 2 allosterically by binding to its pyruvate regulatory site. |
| Q37290895 | Gel-based hippocampal proteomic analysis 2 weeks following traumatic brain injury to immature rats using controlled cortical impact |
| Q41859582 | Global view of cognate kinase activation by the human pyruvate dehydrogenase complex |
| Q38420969 | High-dose vitamin B1 reduces proliferation in cancer cell lines analogous to dichloroacetate |
| Q57050314 | How phosphorylation influences E1 subunit pyruvate dehydrogenase: A computational study |
| Q79344210 | Identification of a canine model of pyruvate dehydrogenase phosphatase 1 deficiency |
| Q41826160 | Interaction of E1 and E3 components with the core proteins of the human pyruvate dehydrogenase complex |
| Q36057621 | Lack of Skeletal Muscle IL-6 Affects Pyruvate Dehydrogenase Activity at Rest and during Prolonged Exercise |
| Q38317294 | Metabolic modulation of cancer: a new frontier with great translational potential |
| Q24318778 | Molecular mechanism for regulation of the human mitochondrial branched-chain alpha-ketoacid dehydrogenase complex by phosphorylation |
| Q42933578 | PGC-1alpha increases PDH content but does not change acute PDH regulation in mouse skeletal muscle. |
| Q24336339 | Pivotal role of the C-terminal DW-motif in mediating inhibition of pyruvate dehydrogenase kinase 2 by dichloroacetate |
| Q89410942 | Pyruvate dehydrogenase complex deficiency is linked to regulatory loop disorder in the αV138M variant of human pyruvate dehydrogenase |
| Q24317423 | Pyruvate dehydrogenase kinase-4 structures reveal a metastable open conformation fostering robust core-free basal activity |
| Q27676239 | Radiation-induced signaling results in mitochondrial impairment in mouse heart at 4 weeks after exposure to X-rays |
| Q42821704 | Recognition of the inner lipoyl-bearing domain of dihydrolipoyl transacetylase and of the blood glucose-lowering compound AZD7545 by pyruvate dehydrogenase kinase 2. |
| Q24533374 | Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites |
| Q44358659 | Regulation of pyruvate dehydrogenase complex activity in plant cells |
| Q24291531 | Site specificity of four pyruvate dehydrogenase kinase isoenzymes toward the three phosphorylation sites of human pyruvate dehydrogenase |
| Q27640758 | Structural basis for flip-flop action of thiamin pyrophosphate-dependent enzymes revealed by human pyruvate dehydrogenase |
| Q24329273 | Structural basis for inactivation of the human pyruvate dehydrogenase complex by phosphorylation: role of disordered phosphorylation loops |
| Q92957648 | Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers |
| Q33761130 | The pyruvate dehydrogenase complexes: structure-based function and regulation |
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