Cabozantinib-induced thyroid dysfunction: a review of two ongoing trials for metastatic bladder cancer and sarcoma

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Cabozantinib-induced thyroid dysfunction: a review of two ongoing trials for metastatic bladder cancer and sarcoma is …
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scholarly articleQ13442814

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P356DOI10.1089/THY.2013.0621
P8608Fatcat IDrelease_c27dfcyh5bhtvnct75ns2g567y
P932PMC publication ID4106376
P698PubMed publication ID24724719

P2093author name stringJames Reynolds
Shivaani Kummar
Francesco S Celi
Ravi A Madan
Andrea B Apolo
Jaydira del Rivero
Sahzene Yavuz
Thomas Shawker
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Sunitinib induces hypothyroidism in advanced cancer patients and may inhibit thyroid peroxidase activityQ36804701
The clinical implications of sunitinib-induced hypothyroidism: a prospective evaluationQ36858013
Unusual case of amiodarone-induced thyrotoxicosis: "illicit" use of a technetium scan to diagnose a transiently toxic thyroid noduleQ36899425
Tyrosine kinase inhibitors and the thyroid as both an unintended and an intended targetQ37254710
Tyrosine kinase inhibitors and modifications of thyroid function tests: a reviewQ37356708
Conditions and drugs interfering with thyroxine absorptionQ37639664
Key predictive factors of axitinib (AG-013736)-induced proteinuria and efficacy: a phase II study in Japanese patients with cytokine-refractory metastatic renal cell CarcinomaQ37926019
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Thyroid dysfunction caused by second-generation tyrosine kinase inhibitors in Philadelphia chromosome-positive chronic myeloid leukemiaQ42867411
Sorafenib-Induced Destructive ThyroiditisQ42913770
Sunitinib-Induced Thyrotoxicosis Followed by Persistent Hypothyroidism with Shrinkage of Thyroid VolumeQ42918821
Clinical characteristics of thyroid abnormalities induced by sunitinib treatment in Japanese patients with renal cell carcinomaQ42928425
Sorafenib-induced hypothyroidism is associated with increased type 3 deiodinationQ43059498
Sunitinib induces hypothyroidism with a markedly reduced vascularityQ43148186
Shrinkage of thyroid volume in sunitinib-treated patients with renal-cell carcinoma: a potential marker of irreversible thyroid dysfunction?Q43167326
Abnormalities of thyroid function in Japanese patients with metastatic renal cell carcinoma treated with sorafenib: a prospective evaluationQ43242171
Sorafenib induced thyroiditis in two patients with hepatocellular carcinomaQ44955867
Sunitinib-associated lymphocytic thyroiditis without circulating antithyroid antibodiesQ46481053
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Thyroid size change by CT monitoring after sorafenib or sunitinib treatment in patients with renal cell carcinoma: comparison with thyroid functionQ47368293
Thyroid dysfunction in patients treated with tyrosine kinase inhibitors, sunitinib, sorafenib and axitinib, for metastatic renal cell carcinomaQ47713907
Tyrosine kinase inhibitors noncompetitively inhibit MCT8-mediated iodothyronine transportQ48819442
Inappropriate elevation of serum thyrotropin levels in patients treated with axitinib.Q50896204
Sunitinib-induced hypothyroidism is due to induction of type 3 deiodinase activity and thyroidal capillary regression.Q51017184
Hypothyroidism after sunitinib treatment for patients with gastrointestinal stromal tumors.Q55042679
A Novel Tyrosine-Kinase Selective Inhibitor, Sunitinib, Induces Transient Hypothyroidism by Blocking Iodine UptakeQ61794209
Color Doppler ultrasonography in patients with subacute thyroiditisQ73383324
Sunitinib (sutent)-induced thyrotoxicosis due to destructive thyroiditis: a case reportQ80831056
Could thyroid dysfunction influence outcome in sunitinib-treated metastatic renal cell carcinoma?Q84304427
P433issue8
P407language of work or nameEnglishQ1860
P304page(s)1223-1231
P577publication date2014-06-05
P1433published inThyroidQ15709940
P1476titleCabozantinib-induced thyroid dysfunction: a review of two ongoing trials for metastatic bladder cancer and sarcoma
P478volume24

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cites work (P2860)
Q38625034Cabozantinib for the treatment of progressive metastatic medullary thyroid cancer
Q97519474Cabozantinib in patients with platinum-refractory metastatic urothelial carcinoma: an open-label, single-centre, phase 2 trial
Q38880117KRAS and HRAS mutations confer resistance to MET targeting in preclinical models of MET-expressing tumor cells.
Q38718947Modulating the function of ATP-binding cassette subfamily G member 2 (ABCG2) with inhibitor cabozantinib
Q38534167Targeting the VEGF pathway in metastatic bladder cancer
Q38778384The Involvement of Hepatocyte Growth Factor-MET-Matrix Metalloproteinase 1 Signaling in Bladder Cancer Invasiveness and Proliferation. Effect of the MET Inhibitor, Cabozantinib (XL184), on Bladder Cancer Cells
Q26796404The treatment landscape in thyroid cancer: a focus on cabozantinib

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