Hematopoietic progenitor cell regulation by CD4+CD25+ T cells

scientific article

Hematopoietic progenitor cell regulation by CD4+CD25+ T cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1182/BLOOD-2009-04-218826
P932PMC publication ID2890189
P698PubMed publication ID20200356
P5875ResearchGate publication ID41722164

P50authorWilliam J. MurphyQ91170042
Angela Panoskaltsis-MortariQ60452140
Bruce R BlazarQ62070764
P2093author name stringRobert B Levy
Isabel Barao
Monica Jones
Maite Urbieta
Roland Jurecic
P2860cites workImmunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseasesQ28131652
Regulatory T cell lineage specification by the forkhead transcription factor foxp3Q28510328
An intersection between the self-reactive regulatory and nonregulatory T cell receptor repertoiresQ28590409
Regulatory T cells prevent catastrophic autoimmunity throughout the lifespan of miceQ29622850
Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-beta signals in vivoQ33723552
Characterization of mouse clonogenic megakaryocyte progenitorsQ34467347
Regulatory CD4(+)CD25(+) T cells in tumors from patients with early-stage non-small cell lung cancer and late-stage ovarian cancer.Q34515741
Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor betaQ34517421
Mast cells are essential intermediaries in regulatory T-cell toleranceQ34559099
Suppression of natural killer cell-mediated bone marrow cell rejection by CD4+CD25+ regulatory T cellsQ34600272
CD4+ CD25+ suppressor T cells: more questions than answersQ34716304
Full restoration of peripheral Foxp3+ regulatory T cell pool by radioresistant host cells in scurfy bone marrow chimerasQ35829151
Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioningQ36227853
CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsivenessQ36370807
Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantationQ36370863
Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumorsQ36402716
NK cell subsets in the regulation of murine hematopoiesis. I. 5E6+ NK cells promote hematopoietic growth in H-2d strain mice.Q36694483
Relationship of cell-cycle expression of Ia-like antigenic determinants on normal and leukemia human granulocyte-macrophage progenitor cells to regulation in vitro by acidic isoferritinsQ37008620
Host CD4+CD25+ T cells can expand and comprise a major component of the Treg compartment after experimental HCTQ37066280
Transforming growth factor beta-induced cell cycle arrest of human hematopoietic cells requires p57KIP2 up-regulation.Q37590120
Control of hematopoietic stem/progenitor cell fate by transforming growth factor-betaQ40650924
Post-hematopoietic cell transplantation control of graft-versus-host disease by donor CD425 T cells to allow an effective graft-versus-leukemia responseQ40651436
Transforming growth factor-beta regulates c-kit message stability and cell-surface protein expression in hematopoietic progenitors.Q41466459
In situ activation and expansion of host tregs: a new approach to enhance donor chimerism and stable engraftment in major histocompatibility complex-matched allogeneic hematopoietic cell transplantationQ41923994
FoxP3+ regulatory T cells restrain splenic extramedullary myelopoiesis via suppression of hemopoietic cytokine-producing T cellsQ42063604
Normal hematopoiesis is maintained by activated bone marrow CD4+ T cellsQ42469876
Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signalingQ42602502
CD4+CD25+ regulatory T cells preserve graft-versus-tumor activity while inhibiting graft-versus-host disease after bone marrow transplantationQ44408941
Lymphokine(s) from isolated T lymphocyte subpopulations support multilineage hematopoietic colony and megakaryocytic colony formationQ44944918
Stem cell repopulation efficiency but not pool size is governed by p27(kip1).Q45872224
Recipient CD4+ T cells that survive irradiation regulate chronic graft-versus-host diseaseQ47586153
TGF-(beta)1 maintains hematopoietic immaturity by a reversible negative control of cell cycle and induces CD34 antigen up-modulationQ49068753
Selective stimulation of T cell subsets with antibody-cytokine immune complexesQ51984700
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3.Q51997055
Cytotoxically impaired transplant recipients can efficiently resist major histocompatibility complex--matched bone marrow allograftsQ54037874
Bone marrow is a reservoir for CD4+CD25+ regulatory T cells that traffic through CXCL12/CXCR4 signalsQ54692947
CD25+CD4+ regulatory T cells prevent graft rejection: CTLA-4- and IL-10-dependent immunoregulation of alloresponsesQ56904642
Comparison of outcomes of unrelated bone marrow and umbilical cord blood transplants in children with acute leukemiaQ58416305
Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expressionQ59048389
Characterization of Foxp3+CD4+CD25+ and IL-10-Secreting CD4+CD25+ T Cells during Cure of ColitisQ61779891
Cord blood transplantation provides better reconstitution of hematopoietic reservoir compared with bone marrow transplantationQ63257374
TGF-beta is a bidirectional modulator of cytokine receptor expression on murine bone marrow cells. Differential effects of TGF-beta 1 and TGF-beta 3Q64008472
The influence of T lymphocyte subsets and humoral factors on colony formation by human bone marrow and blood megakaryocyte progenitor cells in vitroQ68805859
Beta 2-microglobulin-deficient background ameliorates lethal phenotype of the TGF-beta 1 null mouseQ73003010
Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cellsQ74244102
Ligand-activated natural killer T lymphocytes promptly produce IL-3 and GM-CSF in vivo: relevance to peripheral myeloid recruitmentQ74456211
Th1 cells regulate hematopoietic progenitor cell homeostasis by production of oncostatin MQ74471802
Perforin/Fas-ligand double deficiency is associated with macrophage expansion and severe pancreatitisQ77716196
The infusion of ex vivo activated and expanded CD4(+)CD25(+) immune regulatory cells inhibits graft-versus-host disease lethalityQ78033315
Transforming growth factor-beta1 (TGF-beta1) induces thrombopoietin from bone marrow stromal cells, which stimulates the expression of TGF-beta receptor on megakaryocytes and, in turn, renders them susceptible to suppression by TGF-beta itself withQ78225305
CD25+ immunoregulatory T-cells of donor origin suppress alloreactivity after BMTQ78523396
Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantationQ80884347
Absence of major histocompatibility complex class I on neural stem cells does not permit natural killer cell killing and prevents recognition by alloreactive cytotoxic T lymphocytes in vitroQ80984780
P433issue23
P407language of work or nameEnglishQ1860
P1104number of pages10
P304page(s)4934-4943
P577publication date2010-03-03
P1433published inBloodQ885070
P1476titleHematopoietic progenitor cell regulation by CD4+CD25+ T cells
P478volume115