Carbohydrate sulfotransferases: novel therapeutic targets for inflammation, viral infection and cancer

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Carbohydrate sulfotransferases: novel therapeutic targets for inflammation, viral infection and cancer is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S1359-6446(00)01581-6
P698PubMed publication ID11165170

P2093author name stringS Hemmerich
P2860cites workMultiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic lociQ22001455
Sulfotransferases of two specificities function in the reconstitution of high endothelial cell ligands for L-selectinQ22010048
Cloning and characterization of a mammalian N-acetylglucosamine-6-sulfotransferase that is highly restricted to intestinal tissueQ22010555
Molecular cloning and expression of a novel chondroitin 6-O-sulfotransferaseQ22253988
Chromosomal localization and genomic organization for the galactose/ N-acetylgalactosamine/N-acetylglucosamine 6-O-sulfotransferase gene familyQ24290833
Tyrosylprotein sulfotransferase: purification and molecular cloning of an enzyme that catalyzes tyrosine O-sulfation, a common posttranslational modification of eukaryotic proteinsQ24317447
Heparan sulfate proteoglycans of the cardiovascular system. Specific structures emerge but how is synthesis regulated?Q24561731
Crystal structure of the sulfotransferase domain of human heparan sulfate N-deacetylase/ N-sulfotransferase 1Q27617860
Insight into E-selectin/ligand interaction from the crystal structure and mutagenesis of the lec/EGF domainsQ27729350
Heparin structure and interactions with basic fibroblast growth factorQ27732601
The sulfuryl transfer mechanism. Crystal structure of a vanadate complex of estrogen sulfotransferase and mutational analysisQ27765678
Molecular cloning and expression of mouse and human cDNAs encoding heparan sulfate D-glucosaminyl 3-O-sulfotransferaseQ28114813
Molecular cloning and expression of human and mouse tyrosylprotein sulfotransferase-2 and a tyrosylprotein sulfotransferase homologue in Caenorhabditis elegansQ28115054
A novel role for 3-O-sulfated heparan sulfate in herpes simplex virus 1 entryQ28145858
An endothelial ligand for L-selectin is a novel mucin-like moleculeQ28187110
High endothelial venules (HEVs): specialized endothelium for lymphocyte migrationQ28288508
Purification of heparan sulfate D-glucosaminyl 3-O-sulfotransferaseQ28295437
Sulfation in high endothelial venules: cloning and expression of the human PAPS synthetaseQ28646546
Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic miceQ28770154
Very late antigen 4 (VLA4) antagonists as anti-inflammatory agentsQ29399826
Lymphocyte homing and homeostasisQ29619924
A continuous assay for the spectrophotometric analysis of sulfotransferases using aryl sulfotransferase IV.Q30795725
Discovery of Carbohydrate Sulfotransferase Inhibitors from a Kinase-Directed Library We thank Sharon Long and Dave Keating for providing both the NodH sulfotransferase and APS Kinase during our preliminary experiments and Jack Kirsch for [...]Q33180170
Development of eptifibatideQ33781957
Sulfation of N-acetylglucosamine by chondroitin 6-sulfotransferase 2 (GST-5).Q33915045
Carbohydrate sulfotransferases in lymphocyte homingQ33917924
Platelet adhesion receptors: novel targets for anti-thrombotic therapyQ33951293
Chlorate--a potent inhibitor of protein sulfation in intact cellsQ34162808
A sulfated peptide segment at the amino terminus of PSGL-1 is critical for P-selectin bindingQ34297510
Enzymology of human cytosolic sulfotransferasesQ34419466
How do kinases transfer phosphoryl groups?Q34465736
Carbohydrate sulfotransferases: mediators of extracellular communicationQ34487662
Dimerization of P-selectin glycoprotein ligand-1 (PSGL-1) required for optimal recognition of P-selectinQ36256164
Sulfation-dependent recognition of high endothelial venules (HEV)-ligands by L-selectin and MECA 79, and adhesion-blocking monoclonal antibodyQ36364185
L-selectin-deficient mice have impaired leukocyte recruitment into inflammatory sitesQ36364926
Regulation of L-selectin-mediated rolling through receptor dimerizationQ36401579
The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptorQ36530024
Isolation and characterization of natural protein-associated carbohydrate ligands for E-selectinQ36676819
Synthesis of a divalent sialyl Lewis x O-glycan, a potent inhibitor of lymphocyte-endothelium adhesion. Evidence that multivalency enhances the saccharide binding to L-selectinQ38288503
Structure of the O-glycans in GlyCAM-1, an endothelial-derived ligand for L-selectinQ38295258
6'-sulfated sialyl Lewis x is a major capping group of GlyCAM-1.Q38308885
Further characterization of the interaction between L-selectin and its endothelial ligandsQ38327148
Identification of an N-acetylglucosamine-6-0-sulfotransferase activity specific to lymphoid tissue: an enzyme with a possible role in lymphocyte homingQ38334288
Identification of a major carbohydrate capping group of the L-selectin ligand on high endothelial venules in human lymph nodes as 6-sulfo sialyl Lewis X.Q38336922
High-level expression and purification of a recombinant human alpha-1, 3-fucosyltransferase in baculovirus-infected insect cells.Q38343870
Selectins.Q40388550
Adhesion molecules--Part 1.Q40980798
Adhesion molecules--Part II: Blood vessels and blood cellsQ40990588
Sulfuryl transfer: the catalytic mechanism of human estrogen sulfotransferaseQ41036966
Two selectins converge on sulphate. Leukocyte adhesionQ41110602
Cell adhesion: a new target for therapyQ41633641
A novel, high endothelial venule-specific sulfotransferase expresses 6-sulfo sialyl Lewis(x), an L-selectin ligand displayed by CD34.Q41683619
Endothelial L-selectin ligands are likely to recruit lymphocytes into rejecting human heart transplantsQ41899300
Novel synthetic inhibitors of selectin-mediated cell adhesion: synthesis of 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-alpha-D- mannopyranosyloxy)phenyl]hexane (TBC1269).Q42543494
Tyrosine sulfation of the amino terminus of CCR5 facilitates HIV-1 entryQ43694761
A tissue-specific endothelial cell molecule involved in lymphocyte homingQ46344483
Targeting of proteins to the Golgi apparatusQ57357183
Endothelial Sulfated Sialyl Lewis x Glycans, Putative L-Selectin Ligands, Are Preferentially Expressed in Bronchial Asthma but Not in Other Chronic Inflammatory Lung DiseasesQ60191727
Strength in numbers: non-natural polyvalent carbohydrate derivativesQ60502325
Quercetin, a potent and specific inhibitor of the human P-form phenosulfotransferaseQ72045093
Common food additives are potent inhibitors of human liver 17 alpha-ethinyloestradiol and dopamine sulphotransferasesQ72632963
Affinity and kinetic analysis of L-selectin (CD62L) binding to glycosylation-dependent cell-adhesion molecule-1Q74016257
Anti-adhesion cancer therapyQ77402829
P433issue1
P304page(s)27-35
P577publication date2001-01-01
P1433published inDrug Discovery TodayQ3040085
P1476titleCarbohydrate sulfotransferases: novel therapeutic targets for inflammation, viral infection and cancer
P478volume6

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cites work (P2860)
Q60919672AXIN1 in Plasma or Serum Is a Potential New Biomarker for Endometriosis
Q38353775Breast cancer treatment and sulfotransferase
Q34167050Characterization and mutagenesis of Gal/GlcNAc-6-O-sulfotransferases.
Q38437898Comparative Transcriptomics of Buzura suppressaria (Lepidoptera: Geometridae) Assembled De Novo Yield Insights Into Response After Buzura suppressaria Nuclear Polyhedrosis Virus Infection
Q36370988Ectopic LTαβ Directs Lymphoid Organ Neogenesis with Concomitant Expression of Peripheral Node Addressin and a HEV-restricted Sulfotransferase
Q37257032Glycopolymer probes of signal transduction
Q24307713Golgi localization of carbohydrate sulfotransferases is a determinant of L-selectin ligand biosynthesis
Q34364845Identification of 34 novel proinflammatory proteins in a genome-wide macrophage functional screen
Q33246701Induction of PNAd and N-acetylglucosamine 6-O-sulfotransferases 1 and 2 in mouse collagen-induced arthritis
Q34111293Modifications of glycans: biological significance and therapeutic opportunities
Q36182302Recent advances in sulfotransferase enzyme activity assays
Q35946290Strategies for drug discovery by targeting sulfation pathways
Q36577771Sulfate metabolism in mycobacteria
Q44335030Synthesis of 6'-sulfodisaccharides by beta-N-acetylhexosaminidase-catalyzed transglycosylation
Q30960455Synthetic potential of molluscan sulfatases for the library synthesis of regioselectively O-sulfonated D-galacto-sugars

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