Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion

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Phosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion is …
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scholarly articleQ13442814

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P819ADS bibcode2005PNAS..102.5204G
P356DOI10.1073/PNAS.0501412102
P932PMC publication ID555604
P698PubMed publication ID15793002
P5875ResearchGate publication ID7942910

P50authorPietro De CamilliQ1413623
P2093author name stringDerek Toomre
Gilbert Di Paolo
Gianluca Cestra
Manfred Lindau
Liang-Wei Gong
Ester Diaz
Maria-Elena Diaz
P2860cites workPhosphoinositide profiling in complex lipid mixtures using electrospray ionization mass spectrometryQ48280485
Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cellsQ52423917
PIP2 increases the speed of response of synaptotagmin and steers its membrane-penetration activity toward the plasma membrane.Q55038004
ATP-dependent inositide phosphorylation required for Ca2+-activated secretionQ56689852
A Pleckstrin Homology Domain Specific for Phosphatidylinositol 4,5-Bisphosphate (PtdIns-4,5-P2) and Fused to Green Fluorescent Protein Identifies Plasma Membrane PtdIns-4,5-P2as Being Important in ExocytosisQ56689853
Differential Control of the Releasable Vesicle Pools by SNAP-25 Splice Variants and SNAP-23Q58361606
Synaptotagmin function in dense core vesicle exocytosis studied in cracked PC12 cellsQ74262689
Regulation of cytochrome c oxidase activity by c-Src in osteoclastsQ24296720
ARF6 stimulates clathrin/AP-2 recruitment to synaptic membranes by activating phosphatidylinositol phosphate kinase type IgammaQ24675779
Critical role of PIP5KI{gamma}87 in InsP3-mediated Ca(2+) signalingQ24676005
Phosphatidylinositol 4-phosphate 5-kinase alpha is a downstream effector of the small G protein ARF6 in membrane ruffle formationQ28139699
PIP kinase Igamma is the major PI(4,5)P(2) synthesizing enzyme at the synapseQ28198985
Recruitment and regulation of phosphatidylinositol phosphate kinase type 1 gamma by the FERM domain of talinQ28214335
Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle primingQ28504670
Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCsQ28511979
Specific binding of phosphatidylinositol 4,5-bisphosphate to calcium-dependent activator protein for secretion (CAPS), a potential phosphoinositide effector protein for regulated exocytosisQ28565330
Membrane fusion and exocytosisQ29614426
Calcium-regulated exocytosis of dense-core vesicles requires the activation of ADP-ribosylation factor (ARF)6 by ARF nucleotide binding site opener at the plasma membraneQ30441912
ADP-ribosylation factor 6 regulates insulin secretion through plasma membrane phosphatidylinositol 4,5-bisphosphateQ30485892
Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes.Q33584871
Phosphatidylinositol Phosphate Kinases Put PI4,5P 2 in Its PlaceQ34264164
The role of phosphoinositides in membrane transportQ34309086
PI(4,5)P(2) regulation of surface membrane trafficQ34309091
Impaired PtdIns(4,5)P2 synthesis in nerve terminals produces defects in synaptic vesicle traffickingQ34350922
Protein-lipid interactions and phosphoinositide metabolism in membrane traffic: insights from vesicle recycling in nerve terminalsQ34374331
Visualizing cellular phosphoinositide pools with GFP-fused protein-modulesQ34578749
Phosphoinositide regulation of the actin cytoskeletonQ35019759
PI-loting membrane trafficQ35788132
ARF6 regulates a plasma membrane pool of phosphatidylinositol(4,5)bisphosphate required for regulated exocytosisQ36325060
Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagminQ36693214
Patch-clamp techniques for time-resolved capacitance measurements in single cellsQ39297190
Munc13-1 acts as a priming factor for large dense-core vesicles in bovine chromaffin cellsQ40430145
Amphiphysin 2 (Bin1) and T-tubule biogenesis in muscleQ40710117
An open form of syntaxin bypasses the requirement for UNC-13 in vesicle primingQ41768196
Evidence that the inositol phospholipids are necessary for exocytosis. Loss of inositol phospholipids and inhibition of secretion in permeabilized cells caused by a bacterial phospholipase C and removal of ATP.Q41882249
Early requirement for alpha-SNAP and NSF in the secretory cascade in chromaffin cellsQ42037072
Cytosolic Ca2+ acts by two separate pathways to modulate the supply of release-competent vesicles in chromaffin cellsQ42457810
Drosophila CAPS is an essential gene that regulates dense-core vesicle release and synaptic vesicle fusionQ43715213
Synaptotagmin modulation of fusion pore kinetics in regulated exocytosis of dense-core vesiclesQ43787533
Different domains of synaptotagmin control the choice between kiss-and-run and full fusion.Q44557844
Protein kinase C enhances exocytosis from chromaffin cells by increasing the size of the readily releasable pool of secretory granulesQ47330923
P433issue14
P407language of work or nameEnglishQ1860
P304page(s)5204-5209
P577publication date2005-03-25
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titlePhosphatidylinositol phosphate kinase type I gamma regulates dynamics of large dense-core vesicle fusion
P478volume102

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cites work (P2860)
Q35861032An N-terminal Amphipathic Helix Binds Phosphoinositides and Enhances Kalirin Sec14 Domain-mediated Membrane Interactions
Q50611552Arabidopsis phosphatidylinositol-4-monophosphate 5-kinase 4 regulates pollen tube growth and polarity by modulating membrane recycling.
Q33662567Asymmetric localization of Arabidopsis SYP124 syntaxin at the pollen tube apical and sub-apical zones is involved in tip growth
Q30435941Clustering of syntaxin-1A in model membranes is modulated by phosphatidylinositol 4,5-bisphosphate and cholesterol
Q38861831Control of diverse subcellular processes by a single multi-functional lipid phosphatidylinositol 4,5-bisphosphate [PI(4,5)P2].
Q83226421Crumbs organizes the transport machinery by regulating apical levels of PI(4,5)P in
Q26866150Distinct initial SNARE configurations underlying the diversity of exocytosis
Q30429848Docking and fast fusion of synaptobrevin vesicles depends on the lipid compositions of the vesicle and the acceptor SNARE complex-containing target membrane
Q37808139Dynamin and Myosin Regulate Differential Exocytosis from Mouse Adrenal Chromaffin Cells
Q28756803Estradiol induces hypothalamic dendritic spines by enhancing glutamate release: a mechanism for organizational sex differences
Q39775345Exocytosis of post-Golgi vesicles is regulated by components of the endocytic machinery
Q39643866Fusion gains independence
Q37851547How important are Rho GTPases in neurosecretion?
Q28304194Local PIP(2) signals: when, where, and how?
Q35158215Methods for cell-attached capacitance measurements in mouse adrenal chromaffin cell
Q44934953Nonredundant function of secretory carrier membrane protein isoforms in dense core vesicle exocytosis
Q37086717Out, in and back again: PtdIns(4,5)P(2) regulates cadherin trafficking in epithelial morphogenesis.
Q38256514PI(4,5)P₂-binding effector proteins for vesicle exocytosis
Q47160280Phosphatidylinositol 4,5-bisphosphate optical uncaging potentiates exocytosis
Q36790508Phosphatidylinositol 4,5-bisphosphate regulates SNARE-dependent membrane fusion
Q34527046Phosphatidylinositol-4-phosphate-5-kinase alpha deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice
Q90515204Phosphatidylserine is critical for vesicle fission during clathrin-mediated endocytosis
Q36521982Phosphoinositide regulation of neuroexocytosis: adding to the complexity
Q35078016Phosphoinositide signaling: new tools and insights.
Q89621663Phosphoinositides Signaling and Epithelial-to-Mesenchymal Transition: Putative Topic for Basic Toxicological Research
Q27861051Phosphoinositides in cell regulation and membrane dynamics
Q27012953Phosphoinositides: tiny lipids with giant impact on cell regulation
Q37595417Polyamine effects on cell function: Possible central role of plasma membrane PI(4,5)P2.
Q37265344Profilin interaction with phosphatidylinositol (4,5)-bisphosphate destabilizes the membrane of giant unilamellar vesicles
Q30486711Regulation of insulin granule turnover in pancreatic beta-cells by cleaved ICA512.
Q33870516Regulation of insulin secretion by phosphatidylinositol-4,5-bisphosphate
Q36829577Regulation of the actin cytoskeleton by phosphatidylinositol 4-phosphate 5 kinases
Q37989033Role of PI(4,5)P(2) in vesicle exocytosis and membrane fusion
Q36528090Role of phosphoinositides at the neuronal synapse
Q27322925SIRT1 Regulates Thyroid-Stimulating Hormone Release by Enhancing PIP5Kgamma Activity through Deacetylation of Specific Lysine Residues in Mammals
Q34190825Solution single-vesicle assay reveals PIP2-mediated sequential actions of synaptotagmin-1 on SNAREs
Q24671026Stimulation of phosphatidylinositol kinase type I-mediated phosphatidylinositol (4,5)-bisphosphate synthesis by AP-2mu-cargo complexes
Q36116830Structural transitions in the synaptic SNARE complex during Ca2+-triggered exocytosis
Q36542078Supervised membrane swimming: small G-protein lifeguards regulate PIPK signalling and monitor intracellular PtdIns(4,5)P2 pools.
Q37125115Sustained Exocytosis after Action Potential-Like Stimulation at Low Frequencies in Mouse Chromaffin Cells Depends on a Dynamin-Dependent Fast Endocytotic Process
Q38024048Synaptic vesicle endocytosis
Q83669847Synaptotagmin 1 is necessary for the Ca2+ dependence of clathrin-mediated endocytosis
Q28118433The dual phosphatase activity of synaptojanin1 is required for both efficient synaptic vesicle endocytosis and reavailability at nerve terminals
Q89110786The fusion pore, 60 years after the first cartoon
Q37351866The morphology and biochemistry of nanostructures provide evidence for synthesis and signaling functions in human cerebrospinal fluid
Q36852921The nature and efficiency of neurotransmitter exocytosis also depend on physicochemical parameters
Q24634647The neurosecretory vesicle protein phogrin functions as a phosphatidylinositol phosphatase to regulate insulin secretion
Q52584413The type B phosphatidylinositol-4-phosphate 5-kinase 3 is essential for root hair formation in Arabidopsis thaliana.
Q37380696Tweek, an evolutionarily conserved protein, is required for synaptic vesicle recycling
Q37434355Two novel phosphatidylinositol-4-phosphate 5-kinase type Igamma splice variants expressed in human cells display distinctive cellular targeting
Q44030315Type B phosphatidylinositol-4-phosphate 5-kinases mediate Arabidopsis and Nicotiana tabacum pollen tube growth by regulating apical pectin secretion
Q41688196Vesicle Docking Is a Key Target of Local PI(4,5)P2 Metabolism in the Secretory Pathway of INS-1 Cells.

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