Self-tolerance and the composition of T cell repertoire

scientific article

Self-tolerance and the composition of T cell repertoire is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P6179Dimensions Publication ID1024129049
P356DOI10.1385/IR:21:2-3:305
P8608Fatcat IDrelease_stbdad5w6rcc5awjqs6xi4cbbi
P698PubMed publication ID10852131

P2093author name stringBiggs J
Morgan DJ
Hernandez FJ
Nugent CT
Sherman LA
Ko A
Kreuwel HT
Murtaza A
P2860cites workCharacterization of CD8+ T Lymphocytes That Persist After Peripheral Tolerance to a Self Antigen Expressed in the PancreasQ61140467
Antigen concentration and precursor frequency determine the rate of CD8+ T cell tolerance to peripherally expressed antigensQ61140497
Activation of low avidity CTL specific for a self epitope results in tumor rejection but not autoimmunityQ61140536
CD8(+) T cell-mediated spontaneous diabetes in neonatal miceQ61140579
Peripheral tolerance to an islet cell-specific hemagglutinin transgene affects both CD4+ and CD8+ T cellsQ61140647
Expression of two T cell receptor alpha chains: dual receptor T cellsQ61268447
Cytotoxic T cells recognize fragments of the influenza nucleoproteinQ61761274
The fate of adoptively transferred antigen-specific T cells in vivoQ71548698
Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptorQ71930197
Class I-restricted cross-presentation of exogenous self-antigens leads to deletion of autoreactive CD8(+) T cellsQ24653129
T-cell antigen receptor genes and T-cell recognitionQ29619721
Autoreactivity of T cells from nonobese diabetic mice: an I-Ag7-dependent reactionQ32123429
Positive selection of thymocytesQ33366862
Selecting and maintaining a diverse T-cell repertoireQ33783983
Peripheral selection of the T cell repertoireQ34880495
Widespread expression of an autoantigen-GAD65 transgene does not tolerize non-obese diabetic mice and can exacerbate diseaseQ36284342
Clonal anergy blocks in vivo growth of mature T cells and can be reversed in the absence of antigenQ36361696
Anergy and exhaustion are independent mechanisms of peripheral T cell toleranceQ36364608
Breaking self-tolerance in nonobese diabetic miceQ36366502
Ontogeny of T cell tolerance to peripherally expressed antigensQ36453129
Expression of a second receptor rescues self-specific T cells from thymic deletion and allows activation of autoreactive effector functionQ37385909
Genetic control of autoimmune diabetes in the NOD mouseQ40444847
Development and selection of T cells: facts and puzzlesQ40519670
Peripheral tolerance as a multi-step mechanismQ40774179
Development of an I-Ag7-expressing antigen-presenting cell line: intrinsic molecular defect in compact I-Ag7 dimer generation.Q41060298
Tolerant CD8 T cells induced by multiple injections of peptide antigen show impaired TCR signaling and altered proliferative responses in vitro and in vivoQ42464136
Allelic inclusion of T cell receptor alpha genes poses an autoimmune hazard due to low-level expression of autospecific receptorsQ47992225
A functionally compromised intermediate in extrathymic CD8+ T cell deletion.Q52051901
Restriction of in vitro T cell-mediated cytotoxicity in lymphocytic choriomeningitis within a syngeneic or semiallogeneic system.Q55061347
Expression of two T cell receptor α chains on the surface of normal murine T cellsQ57228132
Down-regulation of T cell receptors on self-reactive T cells as a novel mechanism for extrathymic tolerance induction.Q57275625
Binding of immunogenic peptides to Ia histocompatibility moleculesQ59070314
Immunological function of a defined T-cell population tolerized to low-affinity self antigensQ60073490
P433issue2-3
P304page(s)305-313
P577publication date2000-01-01
P1433published inImmunologic ResearchQ15754981
P1476titleSelf-tolerance and the composition of T cell repertoire
P478volume21

Reverse relations

cites work (P2860)
Q44989794Highly diverged MHC class I mismatches are acceptable for haematopoietic stem cell transplantation
Q45383664Increased sensitivity to antigen in high avidity CD8(+) T cells results from augmented membrane proximal T-cell receptor signal transduction
Q30873107TCRs with high affinity for foreign pMHC show self-reactivity
Q34613914The natural killer cell -- friend or foe in autoimmune disease?
Q34265381Tumour immunotherapy: new tools, new treatment modalities and new T-cell antigens

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