AFos dissociates cardiac myocyte hypertrophy and expression of the pathological gene program

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AFos dissociates cardiac myocyte hypertrophy and expression of the pathological gene program is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1161/01.CIR.0000160367.99928.87
P932PMC publication ID1201436
P698PubMed publication ID15795322

P50authorKoichiro KinugawaQ86697753
P2093author name stringCharles Vinson
Carlin S Long
Mark Y Jeong
P2860cites workc-Jun dimerizes with itself and with c-Fos, forming complexes of different DNA binding affinitiesQ28291350
c-Jun N-terminal kinase-interacting protein 1 inhibits gene expression in response to hypertrophic agonists in neonatal rat ventricular myocytesQ28346420
Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathyQ28505358
The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformationQ29400446
Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablationQ31685225
Opposing effects of Jun kinase and p38 mitogen-activated protein kinases on cardiomyocyte hypertrophyQ33774336
MEKK1 is essential for cardiac hypertrophy and dysfunction induced by Gq.Q34020904
Interleukin-1 beta induces cardiac myocyte growth but inhibits cardiac fibroblast proliferation in cultureQ34223350
A role for the p38 mitogen-activated protein kinase pathway in myocardial cell growth, sarcomeric organization, and cardiac-specific gene expressionQ34440843
Cardiac muscle cell hypertrophy and apoptosis induced by distinct members of the p38 mitogen-activated protein kinase familyQ34453631
Myosin heavy chain messenger RNA and protein isoform transitions during cardiac hypertrophy. Interaction between hemodynamic and thyroid hormone-induced signalsQ34565604
Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failureQ34978011
Growth factors, growth factor response elements, and the cardiac phenotypeQ35169934
Thyroid hormone improves function and Ca2+ handling in pressure overload hypertrophy. Association with increased sarcoplasmic reticulum Ca2+-ATPase and alpha-myosin heavy chain in rat heartsQ37372872
Localization and regulation of c-fos and c-jun protooncogene induction by systolic wall stress in normal and hypertrophied rat heartsQ37650751
Adenoviral delivery of A-FOS, an AP-1 dominant negative, selectively inhibits drug resistance in two human cancer cell linesQ38290833
Serum response factor mediates AP-1-dependent induction of the skeletal alpha-actin promoter in ventricular myocytesQ38357989
The C-terminal domain of c-fos is required for activation of an AP-1 site specific for jun-fos heterodimersQ39575770
In vivo regulation of the beta-myosin heavy chain gene in hypertensive rodent heartQ40715290
Growth and hypertrophy of the heart: towards an understanding of cardiac specific and inducible gene expressionQ40786533
The regulation of AP-1 activity by mitogen-activated protein kinasesQ40998182
Adrenergic receptor stimulation of the mitogen-activated protein kinase cascade and cardiac hypertrophyQ42130562
Transgenic expression of sarcoplasmic reticulum Ca(2+) atpase modifies the transition from hypertrophy to early heart failureQ43726347
Regulation of thyroid hormone receptor isoforms in physiological and pathological cardiac hypertrophyQ43750917
Dominant negative mutant of c-Jun inhibits cardiomyocyte hypertrophy induced by endothelin 1 and phenylephrineQ43859251
Overexpression of the sarcoplasmic reticulum Ca(2+)-ATPase improves myocardial contractility in diabetic cardiomyopathyQ43935483
Alpha- and beta-adrenergic stimulation induces distinct patterns of immediate early gene expression in neonatal rat myocardial cells. fos/jun expression is associated with sarcomere assembly; Egr-1 induction is primarily an alpha 1-mediated responseQ44237547
Sustained activation of nuclear factor kappa B and activator protein 1 in chronic heart failureQ44346308
Induction of c-fos gene and protein by growth factors precedes activation of c-mycQ44887897
Positive regulation of the skeletal alpha-actin gene by Fos and Jun in cardiac myocytesQ46099717
Expression of a constitutively activated mutant of the beta-isozyme of protein kinase C in cardiac myocytes stimulates the promoter of the beta-myosin heavy chain isogene.Q46312003
Gq- and ras-dependent pathways mediate hypertrophy of neonatal rat ventricular myocytes following alpha 1-adrenergic stimulation.Q46652497
Interleukin-1beta is a negative transcriptional regulator of alpha1-adrenergic induced gene expression in cultured cardiac myocytesQ46713204
Expression of cellular oncogenes in the myocardium during the developmental stage and pressure-overloaded hypertrophy of the rat heart.Q52251620
A dominant negative to activation protein-1 (AP1) that abolishes DNA binding and inhibits oncogenesis.Q53441453
Rapid induction of the expression of proto-oncogene fos during human monocytic differentiation.Q53547695
Bone and haematopoietic defects in mice lacking c-fosQ58326969
Platelet-derived growth factor induces rapid but transient expression of the c-fos gene and proteinQ59086707
A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in cultureQ62555340
Different requirements for formation of Jun: Jun and Jun: Fos complexesQ69274554
Dimerization specificity of the leucine zipper-containing bZIP motif on DNA binding: prediction and rational designQ70744379
Thyroid hormone influences beta myosin heavy chain (beta MHC) expressionQ72340101
Ras activity is required for phenylephrine-induced activation of mitogen-activated protein kinase in cardiac muscle cellsQ72362916
Stimulation of "stress-regulated" mitogen-activated protein kinases (stress-activated protein kinases/c-Jun N-terminal kinases and p38-mitogen-activated protein kinases) in perfused rat hearts by oxidative and other stressesQ74358725
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)1645-1651
P577publication date2005-03-28
P1433published inCirculationQ578091
P1476titleAFos dissociates cardiac myocyte hypertrophy and expression of the pathological gene program
P478volume111

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cites work (P2860)
Q64228412A Novel Method of Isolating Myofibrils From Primary Cardiomyocyte Culture Suitable for Myofibril Mechanical Study
Q33917067AFos inhibits phenylephrine-mediated contractile dysfunction by altering phospholamban phosphorylation
Q40785458AMP-activated protein kinase α1-sensitive activation of AP-1 in cardiomyocytes
Q58129769Activin Receptor-Like Kinase 4 Haplodeficiency Mitigates Arrhythmogenic Atrial Remodeling and Vulnerability to Atrial Fibrillation in Cardiac Pathological Hypertrophy
Q34398211Cross-talk between angiotensin II and IGF-1-induced connexin 43 expression in human saphenous vein smooth muscle cells
Q42370598Divergence of hypertrophic growth and fetal gene profile: the influence of beta-blockers
Q37310859Gallic acid prevents isoproterenol-induced cardiac hypertrophy and fibrosis through regulation of JNK2 signaling and Smad3 binding activity
Q37395007Involvement of connexin 43 in angiotensin II-induced migration and proliferation of saphenous vein smooth muscle cells via the MAPK-AP-1 signaling pathway
Q36484609Knockout of beta(1)- and beta(2)-adrenoceptors attenuates pressure overload-induced cardiac hypertrophy and fibrosis
Q36528033MAP kinase kinase kinase-2 (MEKK2) regulates hypertrophic remodeling of the right ventricle in hypoxia-induced pulmonary hypertension
Q92541680Molecular mechanisms underlying gallic acid effects against cardiovascular diseases: An update review
Q56335220Network-based predictions of in vivo cardiac hypertrophy
Q46647997Phenylephrine hypertrophy, Ca2+-ATPase (SERCA2), and Ca2+ signaling in neonatal rat cardiac myocytes
Q35995211Propranolol causes a paradoxical enhancement of cardiomyocyte foetal gene response to hypertrophic stimuli
Q28579994Repression of anti-apoptotic genes via AP-1 as a mechanism of apoptosis induction in ventricular cardiomyocytes
Q51763589Restoration of CREB function is linked to completion and stabilization of adaptive cardiac hypertrophy in response to exercise.
Q35106659Sex differences in cardiomyocyte connexin43 expression.
Q43838536T-type Ca²⁺ signalling downregulates MEK1/2 phosphorylation and cross-talk with the RAAS transcriptional response in cardiac myocytes.
Q33295387TrpC3 regulates hypertrophy-associated gene expression without affecting myocyte beating or cell size
Q46318982cAMP-mediated beta-adrenergic signaling negatively regulates Gq-coupled receptor-mediated fetal gene response in cardiomyocytes

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