Nonpharmacological amelioration of age-related learning deficits: the impact of hippocampal theta-triggered training

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Nonpharmacological amelioration of age-related learning deficits: the impact of hippocampal theta-triggered training is …
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scholarly articleQ13442814

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P819ADS bibcode2005PNAS..10213284A
P356DOI10.1073/PNAS.0506515102
P932PMC publication ID1201623
P698PubMed publication ID16150707
P5875ResearchGate publication ID7610838

P2093author name stringMatthew A Seager
Stephen D Berry
Yukiko Asaka
Elizabeth Shurell
Amy L Griffin
Kristin N Mauldin
P2860cites workOscillatory brain states and learning: Impact of hippocampal theta-contingent trainingQ24533733
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Theta oscillations in the hippocampusQ28217796
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Hippocampectomy disrupts trace eye-blink conditioning in rabbitsQ49028754
Medial septal microinfusion of scopolamine disrupts hippocampal activity and trace jaw movement conditioningQ49112066
Effect of age on burst firing characteristics of rat hippocampal pyramidal cellsQ49153416
Hippocampal synaptic plasticity is modulated by theta rhythm in the fascia dentata of adult and aged freely behaving rats.Q52014798
Theta-contingent trial presentation accelerates learning rate and enhances hippocampal plasticity during trace eyeblink conditioning.Q52090012
Trace eyeblink conditioning in rabbits demonstrates heterogeneity of learning ability both between and within age groups.Q52200789
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Place navigation impaired in rats with hippocampal lesionsQ29547869
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Impact of aging on hippocampal function: plasticity, network dynamics, and cognitionQ33966134
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Two-phase computational model training long-term memories in the entorhinal-hippocampal regionQ33981200
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Modulation of cholinergic transmission enhances excitability of hippocampal pyramidal neurons and ameliorates learning impairments in aging animals.Q34266716
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Age-related changes in associative learning: studies in rabbits and ratsQ39552830
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Deficit in selective and divided attention associated with cholinergic basal forebrain immunotoxic lesion produced by 192-saporin; motoric/sensory deficit associated with Purkinje cell immunotoxic lesion produced by OX7-saporinQ41644649
Medial septal lesions retard classical conditioning of the nicitating membrane response in rabbitsQ41653041
Awareness predicts the magnitude of single-cue trace eyeblink conditioningQ41733434
Theta burst stimulation is optimal for induction of LTP at both apical and basal dendritic synapses on hippocampal CA1 neuronsQ42453633
Functional connectivity between the red nucleus and the hippocampus supports the role of hippocampal formation in sensorimotor integrationQ42462532
Age-related enhancement of the slow outward calcium-activated potassium current in hippocampal CA1 pyramidal neurons in vitro.Q44102456
Spatial memory and hippocampal functionQ44136977
Theta-frequency synaptic potentiation in CA1 in vitro distinguishes cognitively impaired from unimpaired aged Fischer 344 rats.Q44213515
Alterations in the balance of protein kinase and phosphatase activities and age-related impairments of synaptic transmission and long-term potentiationQ44287483
Hippocampectomy impairs the memory of recently, but not remotely, acquired trace eyeblink conditioned responsesQ46100838
Classical conditioning: the Rosetta stone for brain substrates of age-related deficits in learning and memoryQ46276278
Theta pattern stimulation and the induction of LTP: the sequence in which synapses are stimulated determines the degree to which they potentiateQ46487269
Classical conditioning, awareness, and brain systemsQ46618706
Laminar selectivity of the cholinergic suppression of synaptic transmission in rat hippocampal region CA1: computational modeling and brain slice physiology.Q48108013
Local modulation of basal forebrain: effects on working and reference memory.Q48108100
No apparent age differences in hippocampal theta frequency in rabbits aged 3-50 monthsQ48118889
Prediction of learning rate from the hippocampal electroencephalogramQ48182265
Neuronal plasticity in the limbic system during classical conditioning of the rabbit nictitating membrane response. I. The hippocampusQ48195025
Scopolamine disruption of behavioral and hippocampal responses in appetitive trace classical conditioningQ48231291
Hippocampal age differences reoccur after modification of stimulus configurations in rabbit jaw movement conditioningQ48432216
Alterations in the properties of hippocampal pyramidal neurons in the aged rat.Q48471113
Age-related disruption of trace but not delay classical conditioning of the rabbit's nictitating membrane responseQ48523277
Intraseptal scopolamine has differential effects on Pavlovian eye blink and heart rate conditioningQ48523289
Delayed acquisition of behavioral and hippocampal responses during jaw movement conditioning in aging rabbitsQ48537809
Classical conditioning of the eyelid response in rabbits as a model system for the study of brain mechanisms of learning and memory in agingQ48538746
Prolonged Ca2+-dependent afterhyperpolarizations in hippocampal neurons of aged ratsQ48600069
The effect of aging on experience-dependent plasticity of hippocampal place cells.Q48633391
Disruption of decrements in conditioned stimulus processing by selective removal of hippocampal cholinergic input.Q48679298
Disruption of trace conditioning of the nictitating membrane response in rabbits by central cholinergic blockadeQ48711772
P433issue37
P407language of work or nameEnglishQ1860
P1104number of pages5
P304page(s)13284-13288
P577publication date2005-09-06
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleNonpharmacological amelioration of age-related learning deficits: the impact of hippocampal theta-triggered training
P478volume102

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Q27692535Harnessing the power of theta: natural manipulations of cognitive performance during hippocampal theta-contingent eyeblink conditioning
Q26768146Hippocampal Non-Theta-Contingent Eyeblink Classical Conditioning: A Model System for Neurobiological Dysfunction
Q34133218Hippocampal Ripple-Contingent Training Accelerates Trace Eyeblink Conditioning and Retards Extinction in Rabbits
Q27309010Learning to learn: theta oscillations predict new learning, which enhances related learning and neurogenesis
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Q34501389When the brain is prepared to learn: enhancing human learning using real-time fMRI.

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