Combined logical and data-driven models for linking signalling pathways to cellular response.

scientific article

Combined logical and data-driven models for linking signalling pathways to cellular response. is …
instance of (P31):
scholarly articleQ13442814

External links are
P8978DBLP publication IDjournals/bmcsb/MelasMMWA11
P6179Dimensions Publication ID1029114727
P356DOI10.1186/1752-0509-5-107
P932PMC publication ID3145575
P698PubMed publication ID21729292
P5875ResearchGate publication ID51467382

P50authorThomas S WeissQ39813494
Ioannis MelasQ57158709
Leonidas G AlexopoulosQ90911115
P2093author name stringAlexander Mitsos
Dimitris E Messinis
P2860cites workThe Hallmarks of CancerQ221226
ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular ContextQ21284234
Global cancer statistics, 2002Q27860562
Immunity, Inflammation, and CancerQ27861048
Molecular classification of cancer: class discovery and class prediction by gene expression monitoringQ27861072
Mass spectrometry-based proteomicsQ28182890
A quantitative analysis of kinase inhibitor selectivityQ28264038
A unique structure for epidermal growth factor receptor bound to GW572016 (Lapatinib): relationships among protein conformation, inhibitor off-rate, and receptor activity in tumor cellsQ28282744
Hepatocellular carcinoma: epidemiology and molecular carcinogenesisQ28306363
Identifying drug effects via pathway alterations using an integer linear programming optimization formulation on phosphoproteomic dataQ28472011
ON/OFF and beyond--a boolean model of apoptosisQ28472140
Training signaling pathway maps to biochemical data with constrained fuzzy logic: quantitative analysis of liver cell responses to inflammatory stimuliQ28477321
Growth of human hepatoma cells lines with differentiated functions in chemically defined mediumQ29617962
Evolving concepts of rheumatoid arthritisQ29618020
Causal protein-signaling networks derived from multiparameter single-cell dataQ29619136
Data-driven modelling of signal-transduction networksQ31068825
Flexible informatics for linking experimental data to mathematical models via DataRailQ31143834
Fuzzy logic analysis of kinase pathway crosstalk in TNF/EGF/insulin-induced signalingQ33426337
The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput dataQ33491534
Networks inferred from biochemical data reveal profound differences in toll-like receptor and inflammatory signaling between normal and transformed hepatocytesQ33575787
Computational modeling with forward and reverse engineering links signaling network and genomic regulatory responses: NF-kappaB signaling-induced gene expression responses in inflammationQ33596981
Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transductionQ33668279
Proteomics to study genes and genomesQ33906818
The ins and outs of signallingQ34311175
Physicochemical modelling of cell signalling pathways.Q34576205
Regulation of cytokine signaling and inflammationQ34830660
Building with a scaffold: emerging strategies for high- to low-level cellular modelingQ35146255
The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signalingQ35479152
A biological approach to computational models of proteomic networksQ36365865
A logical analysis of T cell activation and anergyQ36454568
Signal transduction of inflammatory cytokines and tumor developmentQ36492439
Genetic screening for signal transduction in the era of network biologyQ36718781
Transforming growth factor-beta and the immune response to malignant diseaseQ36987655
A review of erlotinib--an oral, selective epidermal growth factor receptor tyrosine kinase inhibitorQ37678436
Logic-based models for the analysis of cell signaling networksQ37708260
A multipathway phosphoproteomic signaling network model of idiosyncratic drug- and inflammatory cytokine-induced toxicity in human hepatocytesQ37721819
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunityQ40351340
Charitable State-Controlled Foundation Human Tissue and Cell Research: Ethic and Legal Aspects in the Supply of Surgically Removed Human Tissue For Research in the Academic and Commercial Sector in GermanyQ40496031
Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cellsQ40602668
E-CELL: software environment for whole-cell simulationQ40822088
Personalizing medicine: a systems biology perspectiveQ43142778
Anti-tumor activity of GW572016: a dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathwaysQ44127144
Cellular damage to human hepatocytes through repeated application of 5-aminolevulinic acidQ44381049
Ikappa-B kinase-2 inhibitor blocks inflammation in human airway smooth muscle and a rat model of asthmaQ46588782
A systems model of signaling identifies a molecular basis set for cytokine-induced apoptosis.Q51307059
Obesity, inflammatory signaling, and hepatocellular carcinoma-an enlarging link.Q53479578
Quantification of Short Term Signaling by the Epidermal Growth Factor ReceptorQ56689833
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunctionQ74191142
A compendium of signals and responses triggered by prodeath and prosurvival cytokinesQ80394534
P304page(s)107
P577publication date2011-07-05
P1433published inBMC Systems BiologyQ4835949
P1476titleCombined logical and data-driven models for linking signalling pathways to cellular response
P478volume5

Reverse relations

cites work (P2860)
Q30620270A crowd-sourcing approach for the construction of species-specific cell signaling networks
Q41211496Advances and challenges in logical modeling of cell cycle regulation: perspective for multi-scale, integrative yeast cell models.
Q37619223Can case study approaches speed implementation of the NRC report: "toxicity testing in the 21st century: a vision and a strategy?".
Q59329208Computational Modeling and Reverse Engineering to Reveal Dominant Regulatory Interactions Controlling Osteochondral Differentiation: Potential for Regenerative Medicine
Q36524173Computational model for autophagic vesicle dynamics in single cells
Q92451177Connecting signaling and metabolic pathways in EGF receptor-mediated oncogenesis of glioblastoma
Q34207814Construction of large signaling pathways using an adaptive perturbation approach with phosphoproteomic data
Q28539118Leveraging systems biology approaches in clinical pharmacology
Q28547548Network reconstruction based on proteomic data and prior knowledge of protein connectivity using graph theory
Q35861710Network-Based Analysis of Nutraceuticals in Human Hepatocellular Carcinomas Reveals Mechanisms of Chemopreventive Action
Q34505131Non Linear Programming (NLP) formulation for quantitative modeling of protein signal transduction pathways
Q34318470Nonparametric simulation of signal transduction networks with semi-synchronized update
Q36268781Sig2GRN: a software tool linking signaling pathway with gene regulatory network for dynamic simulation
Q35076233Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge

Search more.