Functional analysis of conserved non-coding regions around the short stature hox gene (shox) in whole zebrafish embryos

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Functional analysis of conserved non-coding regions around the short stature hox gene (shox) in whole zebrafish embryos is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...621498K
P356DOI10.1371/JOURNAL.PONE.0021498
P932PMC publication ID3123344
P698PubMed publication ID21731768
P5875ResearchGate publication ID51469804

P50authorGreg ElgarQ30519112
P2093author name stringHeather Callaway
Gayle K McEwen
Emma J Kenyon
P2860cites workTurner syndrome and Xp deletions: clinical and molecular studies in 47 patientsQ77148833
Phenotypes Associated with SHOX DeficiencyQ77337722
Minor change, major difference: divergent functions of highly conserved cis-regulatory elements subsequent to whole genome duplication eventsQ34558026
Enhancer elements upstream of the SHOX gene are active in the developing limbQ41736356
Ancient duplicated conserved noncoding elements in vertebrates: a genomic and functional analysisQ42274741
Modulation of epidermal cell shaping and extracellular matrix during caudal fin morphogenesis in the zebra fish Brachydanio rerioQ42436329
Homozygous deletion of SHOX in a mentally retarded male with Langer mesomelic dysplasiaQ43076209
Evidence that mechanisms of fin development evolved in the midline of early vertebrates.Q47193446
Long-range conserved non-coding SHOX sequences regulate expression in developing chicken limb and are associated with short stature phenotypes in human patientsQ50702801
Léri-Weill syndrome as part of a contiguous gene syndrome at Xp22.3.Q51985004
Expression of the short stature homeobox gene Shox is restricted by proximal and distal signals in chick limb buds and affects the length of skeletal elementsQ52010079
Activator effect of coinjected enhancers on the muscle-specific expression of promoters in zebrafish embryosQ52193396
Anterior Duplication of the Sonic hedgehog Expression Pattern in the Pectoral Fin Buds of Zebrafish Treated with Retinoic AcidQ52207450
Independent Hox-cluster duplications in lampreysQ56991607
CompleteSHOX deficiency causes Langer mesomelic dysplasiaQ57828223
The development of the paired fins in the Zebrafish (Danio rerio)Q60307652
Highly conserved non-coding sequences are associated with vertebrate developmentQ21092819
SHOT, a SHOX-related homeobox gene, is implicated in craniofacial, brain, heart, and limb developmentQ24314232
PHOG, a candidate gene for involvement in the short stature of Turner syndromeQ24323155
The mouse Engrailed-1 gene and ventral limb patterningQ24336735
Stages of embryonic development of the zebrafishQ27860947
Pseudoautosomal deletions encompassing a novel homeobox gene cause growth failure in idiopathic short stature and Turner syndromeQ28237330
Mutation and deletion of the pseudoautosomal gene SHOX cause Leri-Weill dyschondrosteosisQ28271044
Induction of the LIM homeobox gene Lmx1 by WNT6a establishes dorsoventral pattern in the vertebrate limbQ28291179
Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking developmentQ28506813
Shox2 function couples neural, muscular and skeletal development in the proximal forelimbQ28586634
Shared developmental mechanisms pattern the vertebrate gill arch and paired fin skeletonsQ28754770
LAGAN and Multi-LAGAN: efficient tools for large-scale multiple alignment of genomic DNAQ28775786
Sonic hedgehog mediates the polarizing activity of the ZPAQ29616565
CONDOR: a database resource of developmentally associated conserved non-coding elementsQ33296096
Constraints on reinitiation of translation in mammalsQ34004574
Interference of nonsense mutations with eukaryotic messenger RNA stabilityQ34037213
A functionally conserved homolog of the Drosophila segment polarity gene hh is expressed in tissues with polarizing activity in zebrafish embryosQ34346998
The short stature homeobox gene SHOX is involved in skeletal abnormalities in Turner syndrome.Q34508002
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectDanio rerioQ169444
P304page(s)e21498
P577publication date2011-06-24
P1433published inPLOS OneQ564954
P1476titleFunctional analysis of conserved non-coding regions around the short stature hox gene (shox) in whole zebrafish embryos
P478volume6

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cites work (P2860)
Q37147401A Track Record on SHOX: From Basic Research to Complex Models and Therapy
Q47768125Comparative transgenic analysis of enhancers from the human SHOX and mouse Shox2 genomic regions
Q41718774In vivo loss of function study reveals the short stature homeobox-containing (shox) gene plays indispensable roles in early embryonic growth and bone formation in zebrafish
Q39854835Microduplications at the pseudoautosomal SHOX locus in autism spectrum disorders and related neurodevelopmental conditions
Q48172096On the Evolution of the Cardiac Pacemaker
Q36774245Phenotypic characterization of patients with deletions in the 3’-flanking SHOXregion
Q36343359Profiling of conserved non-coding elements upstream of SHOX and functional characterisation of the SHOX cis-regulatory landscape
Q26748496SHOX Haploinsufficiency as a Cause of Syndromic and Nonsyndromic Short Stature
Q22122079Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
Q33958594Spectrum of phenotypic anomalies in four families with deletion of the SHOX enhancer region.
Q34055731Structural and numerical changes of chromosome X in patients with esophageal atresia
Q33774631The Short-Stature Homeobox-Containing Gene (shox/SHOX) Is Required for the Regulation of Cell Proliferation and Bone Differentiation in Zebrafish Embryo and Human Mesenchymal Stem Cells

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