review article | Q7318358 |
scholarly article | Q13442814 |
P6179 | Dimensions Publication ID | 1036223701 |
P356 | DOI | 10.1208/S12248-010-9196-Y |
P932 | PMC publication ID | 2895451 |
P698 | PubMed publication ID | 20440589 |
P5875 | ResearchGate publication ID | 44571456 |
P2093 | author name string | Louis S Premkumar | |
P2860 | cites work | An ankyrin-like protein with transmembrane domains is specifically lost after oncogenic transformation of human fibroblasts | Q22009055 |
Cellular basis of itch sensation | Q22337064 | ||
The capsaicin receptor: a heat-activated ion channel in the pain pathway | Q24322558 | ||
Pungent products from garlic activate the sensory ion channel TRPA1 | Q24529826 | ||
Acid-sensing ion channel 3 matches the acid-gated current in cardiac ischemia-sensing neurons | Q24544425 | ||
Deletion of vanilloid receptor 1-expressing primary afferent neurons for pain control | Q24568208 | ||
Pathological and protective roles of glia in chronic pain | Q24646738 | ||
TRPV1: a target for next generation analgesics | Q24649067 | ||
TRP channel activation by reversible covalent modification | Q24677242 | ||
Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia | Q28144926 | ||
P2X receptors in sensory neurones | Q28144989 | ||
Pain mechanisms: labeled lines versus convergence in central processing | Q28185812 | ||
painless, a Drosophila Gene Essential for Nociception | Q28198237 | ||
Molecular mechanisms of nociception | Q28216291 | ||
Mechanisms of opioid-induced tolerance and hyperalgesia | Q28242425 | ||
The TRPV1 receptor and nociception | Q28281263 | ||
Transient receptor potential cation channels in disease | Q28284143 | ||
Opioid-receptor mRNA expression in the rat CNS: anatomical and functional implications | Q28287619 | ||
TRP channels: targets for the relief of pain | Q28290040 | ||
Body-temperature maintenance as the predominant function of the vanilloid receptor TRPV1 | Q28294635 | ||
Opioid-induced hyperalgesia: a qualitative systematic review | Q28299687 | ||
TRPV1 antagonists: the challenges for therapeutic targeting | Q28304644 | ||
TRPA1 contributes to cold, mechanical, and chemical nociception but is not essential for hair-cell transduction | Q28505709 | ||
TRPA1 mediates the inflammatory actions of environmental irritants and proalgesic agents | Q28508162 | ||
Impaired nociception and pain sensation in mice lacking the capsaicin receptor | Q28511370 | ||
TRPA1 induced in sensory neurons contributes to cold hyperalgesia after inflammation and nerve injury | Q28769527 | ||
Neuronal plasticity: increasing the gain in pain | Q29615421 | ||
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines | Q29615510 | ||
BDNF from microglia causes the shift in neuronal anion gradient underlying neuropathic pain | Q29616106 | ||
Noxious cold ion channel TRPA1 is activated by pungent compounds and bradykinin | Q29616107 | ||
Vanilloid (Capsaicin) receptors and mechanisms | Q29617371 | ||
Arterial response to shear stress critically depends on endothelial TRPV4 expression | Q30833847 | ||
Tonic descending facilitation from the rostral ventromedial medulla mediates opioid-induced abnormal pain and antinociceptive tolerance. | Q31813611 | ||
Incomplete cross tolerance and multiple mu opioid peptide receptors | Q31887588 | ||
Selective targeting of TRPV1 expressing sensory nerve terminals in the spinal cord for long lasting analgesia | Q33503225 | ||
Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain sensitization. | Q33716248 | ||
Mechanisms of pain | Q33946821 | ||
Physiologic and antinociceptive effects of intrathecal resiniferatoxin in a canine bone cancer model | Q33991000 | ||
Neurogenic inflammation. A model for studying efferent actions of sensory nerves | Q46247803 | ||
Level of Toll-like receptor agonist exposure differentially determines chemokine production in humans | Q46305481 | ||
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel and selective transient receptor potential type V1 receptor antagonist, blocks channel activation by vanilloids, heat, and acid | Q46443695 | ||
Clinical response to morphine in cancer patients and genetic variation in candidate genes | Q46653217 | ||
Tonic endovanilloid facilitation of glutamate release in brainstem descending antinociceptive pathways. | Q46852210 | ||
Hearing impairment in TRPV4 knockout mice | Q48878721 | ||
Revisiting TRPC1 and TRPC6 mechanosensitivity. | Q50660189 | ||
Release of gamma-aminobutyric acid in the dorsal horn and suppression of tactile allodynia by spinal cord stimulation in mononeuropathic rats. | Q51565601 | ||
Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists | Q69349896 | ||
Myelinated afferent fibres responding specifically to noxious stimulation of the skin | Q72291143 | ||
Pronounced changes in the activity of nociceptive modulatory neurons in the rostral ventromedial medulla in response to prolonged thermal noxious stimuli | Q72374035 | ||
Ectopic sensory discharges and paresthesiae in patients with disorders of peripheral nerves, dorsal roots and dorsal columns | Q72407089 | ||
Hyperexcitability at sites of nerve injury depends on voltage-sensitive Na+ channels | Q72816452 | ||
Rapid sprouting of sympathetic axons in dorsal root ganglia of rats with a chronic constriction injury | Q73337716 | ||
Involvement of increased excitatory amino acids and intracellular Ca2+ concentration in the spinal dorsal horn in an animal model of neuropathic pain | Q73574695 | ||
Bradykinin activates a cross-signaling pathway between sensory and adrenergic nerve endings in the heart: a novel mechanism of ischemic norepinephrine release? | Q78016259 | ||
Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats | Q82873313 | ||
TRP channels and pain | Q83830678 | ||
TRPV1+ sensory neurons control beta cell stress and islet inflammation in autoimmune diabetes | Q34001477 | ||
Neuronal plasticity and signal transduction in nociceptive neurons: implications for the initiation and maintenance of pathological pain | Q34132344 | ||
The kallikrein-kinin system: current and future pharmacological targets. | Q34452928 | ||
The neurobiology of opioid dependence: implications for treatment | Q34787830 | ||
Transient receptor potential channels: targeting pain at the source | Q34912798 | ||
Dissociation of the opioid receptor mechanisms that control mechanical and heat pain | Q34986633 | ||
CB2 cannabinoid receptor agonists: pain relief without psychoactive effects? | Q35054351 | ||
Mechanosensation and pain | Q35884821 | ||
Preventing the development of complex regional pain syndrome after surgery | Q35927947 | ||
The mechanosensitive nature of TRPV channels | Q36134906 | ||
Molecular mechanisms of neuropathic pain-phenotypic switch and initiation mechanisms | Q36197310 | ||
Interleukin-1 and neuronal injury | Q36202191 | ||
Synaptic modulation in pain pathways. | Q36214190 | ||
Spinal and supraspinal contributions to central sensitization in peripheral neuropathy | Q36281892 | ||
Mu opioid receptor regulation and opiate responsiveness | Q36341679 | ||
Influence of TRPV1 on diabetes-induced alterations in thermal pain sensitivity | Q36509492 | ||
The emerging role of TRP channels in mechanisms of temperature and pain sensation | Q36726641 | ||
The vanilloid receptor TRPV1: 10 years from channel cloning to antagonist proof-of-concept | Q36803753 | ||
TRP channel and cardiovascular disease | Q37174911 | ||
Pharmacological blockade of TRPA1 inhibits mechanical firing in nociceptors | Q37190540 | ||
Transient receptor potential A1 is a sensory receptor for multiple products of oxidative stress | Q37258131 | ||
Molecular mechanisms of TRPV4-mediated neural signaling | Q37348481 | ||
Roles of transient receptor potential channels in pain | Q37388690 | ||
Hot flash: TRPV channels in the brain. | Q37414701 | ||
Synaptic plasticity in the spinal dorsal horn | Q37476040 | ||
TRP channel antagonists for pain--opportunities beyond TRPV1. | Q37541918 | ||
The sensory-efferent function of capsaicin-sensitive sensory neurons | Q39631475 | ||
Importance of the non-selective cation channel TRPV1 for microglial reactive oxygen species generation. | Q39812135 | ||
Pain, nociception and spinal opioid receptors | Q40096837 | ||
Insights into opioid action in the intestinal tract | Q41293298 | ||
Hypotonic shocks activate rat TRPV4 in yeast in the absence of polyunsaturated fatty acids. | Q41872715 | ||
Capsaicin receptor TRPV1 in urothelium of neurogenic human bladders and effect of intravesical resiniferatoxin. | Q42474245 | ||
Evidence for a functional role of endothelial transient receptor potential V4 in shear stress-induced vasodilatation | Q42494772 | ||
TRPA1 modulates mechanotransduction in cutaneous sensory neurons. | Q42555945 | ||
Opioid action on respiratory neuron activity of the isolated respiratory network in newborn rats | Q43749680 | ||
PGE(2) selectively blocks inhibitory glycinergic neurotransmission onto rat superficial dorsal horn neurons | Q43820595 | ||
Cardiac vanilloid receptor 1-expressing afferent nerves and their role in the cardiogenic sympathetic reflex in rats | Q44493505 | ||
Putative role of epithelial sodium channels (ENaC) in the afferent limb of cardio renal reflexes in rats | Q44615499 | ||
Sensory nerve desensitization by resiniferatoxin improves glucose tolerance and increases insulin secretion in Zucker Diabetic Fatty rats and is associated with reduced plasma activity of dipeptidyl peptidase IV. | Q45284220 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | chronic pain | Q1088113 |
P304 | page(s) | 361-370 | |
P577 | publication date | 2010-05-04 | |
P1433 | published in | The AAPS Journal | Q10695361 |
P1476 | title | Targeting TRPV1 as an alternative approach to narcotic analgesics to treat chronic pain conditions | |
P478 | volume | 12 |
Q40979775 | A Combined Water Extract of Frankincense and Myrrh Alleviates Neuropathic Pain in Mice via Modulation of TRPV1. |
Q24620790 | A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene |
Q35216840 | Activation characteristics of transient receptor potential ankyrin 1 and its role in nociception |
Q39588200 | Assessment of Free Drug Concentration in Cyclodextrin Formulations Is Essential to Determine Drug Potency in Functional In Vitro Assays. |
Q33967275 | Capsaicin induces "brite" phenotype in differentiating 3T3-L1 preadipocytes |
Q37937444 | Current and emerging "at-site" pain medications: a review |
Q97882666 | Efficacy of intermittent epidural dexamethasone bolus for zoster-associated pain beyond the acute phase |
Q41566415 | Expression-dependent pharmacology of transient receptor potential vanilloid subtype 1 channels in Xenopus laevis oocytes |
Q26801569 | Herpes Zoster and Postherpetic Neuralgia: Practical Consideration for Prevention and Treatment |
Q28681983 | How Far Could We Go with Open Data - A Case Study for TRPV1 Antagonists |
Q35894592 | Hunting for origins of migraine pain: cluster analysis of spontaneous and capsaicin-induced firing in meningeal trigeminal nerve fibers. |
Q58770772 | Identification of key genes and pathways involved in response to pain in goat and sheep by transcriptome sequencing |
Q39265748 | Is electrical brain activity a reliable biomarker for opioid analgesia in the gut? |
Q35690123 | Modulation of spinal cord synaptic activity by tumor necrosis factor α in a model of peripheral neuropathy |
Q39023266 | Novel scaffolds for modulation of TRPV1 identified with pharmacophore modeling and virtual screening. |
Q37937421 | Perineural invasion and associated pain in pancreatic cancer |
Q50111328 | Potential Uses of Isolated Toxin Peptides in Neuropathic Pain Relief: A Literature Review |
Q49609102 | Preclinical characterization of three transient receptor potential vanilloid receptor 1 antagonists for early use in human intradermal microdose analgesic studies. |
Q36819550 | Preservation of acute pain and efferent functions following intrathecal resiniferatoxin-induced analgesia in rats |
Q35168721 | Streptozotocin-induced early thermal hyperalgesia is independent of glycemic state of rats: role of transient receptor potential vanilloid 1(TRPV1) and inflammatory mediators |
Q38984941 | TRP channels: potential drug target for neuropathic pain |
Q48701369 | TRPV1 channels regulate cortical excitability in humans |
Q28741571 | Transient receptor potential channel polymorphisms are associated with the somatosensory function in neuropathic pain patients |
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