Neuropharmacology of control of respiratory rhythm and pattern in mature mammals

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Neuropharmacology of control of respiratory rhythm and pattern in mature mammals is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0163-7258(00)00059-0
P698PubMed publication ID10882812

P2093author name stringOkazaki M
Takeda R
Haji A
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Potencies of Doxapram and Hypoxia in Stimulating Carotid-body Chemoreceptors and Ventilation in Anesthetized CatsQ52717612
On the regulation of depth and rate of breathing.Q52734735
A GABA-mediated inhibition of neurones in the nucleus tractus solitarius of the cat that respond to electrical stimulation of the carotid sinus nerve.Q53793051
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Second messenger-induced modulation of the excitability of respiratory neurones.Q48255051
Serotoninergic and non-serotoninergic responses of phrenic motoneurones to raphe stimulation in the cat.Q48281606
NMDA receptor-mediated inspiratory off-switching in pneumotaxic-disconnected catsQ48289051
Pulmonary stretch receptor afferents activate excitatory amino acid receptors in the nucleus tractus solitarii in rats.Q48297573
Respiratory motoneuronal activity is altered by injections of picomoles of glutamate into cat brain stemQ48318694
Effects of GABAB receptor agonists and antagonists on the bulbar respiratory network in cat.Q48321063
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Effects of baclofen and gamma-aminobutyric acid on different types of medullary respiratory neuronsQ48331616
Variations in membrane potential trajectory of post-inspiratory neurons in the ventrolateral medulla of the cat.Q48346884
Differential effects of GABAA receptor antagonists in the control of respiratory neuronal discharge patternsQ48348900
Central respiratory stimulation produced by thyrotropin-releasing hormone in the cat.Q48372815
The non-uniform character of expiratory synaptic activity in expiratory bulbospinal neurones of the cat.Q48388207
Serotonin innervation patterns differ among the various medullary motoneuronal groups involved in upper airway controlQ48390869
Two brain cholecystokinin receptors: implications for behavioral actionsQ48417682
CCK modulates inhibitory synaptic transmission in the solitary complex through CCKB sitesQ48428709
The distribution of monosynaptic connexions from inspiratory bulbospinal neurones to inspiratory motoneurones in the cat.Q48437886
The detection of monosynaptic connexions from inspiratory bulbospinal neurones to inspiratory motoneurones in the cat.Q48437919
Selective lesioning of the cat pre-Bötzinger complex in vivo eliminates breathing but not gaspingQ48464967
The role of inhibitory amino acids in control of respiratory motor output in an arterially perfused rat.Q48465658
Differential respiratory patterns induced by opioids applied to the ventral medullary and dorsal pontine surfaces of catsQ48474838
Control of abdominal muscles by brain stem respiratory neurons in the cat.Q48476311
Synaptic interaction between medullary respiratory neurones during apneusis induced by NMDA-receptor blockade in cat.Q48487892
The ultrastructural localization of enkephalin and substance P immunoreactivities in the nucleus tractus solitarii of the cat.Q48507120
The influence of increased brain 5-hydroxytryptamine upon the respiratory activity of catsQ48507966
Possible involvement of central adrenaline neurons in vasomotor and respiratory control. Studies with clonidine and its interactions with piperoxane and yohimbineQ48529589
Synchronized high frequency synaptic potentials in medullary respiratory neuronsQ48537888
Intracellular signal pathways controlling respiratory neuronsQ48572802
Gamma-aminobutyric acid type A receptor blockade at the intermediate area of the ventral surface of the medulla counteracts the cardiorespiratory depression produced by intravenous midazolamQ48598117
RTN TRH causes prolonged respiratory stimulationQ48629509
Monosynaptic inhibition of phrenic motoneurons: a long descending projection from Botzinger neuronsQ48632083
Anesthesia selectively reduces hypoglossal nerve activity by actions upon the brain stemQ48638065
Synaptic response of bulbar respiratory neurons to hypercapnic stimulation in peripherally chemodenervated catsQ48640068
Action of nicotine on the respiratory activity of the diaphragm and genioglossus muscles and the nerves that innervate themQ48641495
Excitatory effects of iontophoretically applied substance P on neurons in the nucleus tractus solitarius of the cat: lack of interaction with opiates and opioidsQ48642833
Axonal projections from the rostral expiratory neurones of the Bötzinger complex to medulla and spinal cord in the cat.Q48670212
Antagonistic effects of somatostatin and substance P on respiratory regulation in the rat ventrolateral medulla oblongataQ48673687
Discharge properties of dorsal medullary inspiratory neurons: relation to pulmonary afferent and phrenic efferent dischargeQ48685867
Opposing effects of 5-hydroxytryptamine on two types of medullary inspiratory neurons with distinct firing patternsQ48694919
Two descending medullary inspiratory pathways to phrenic motoneuronesQ48702807
GABA, receptor mediated fast synaptic inhibition in the rabbit brain-stem respiratory systemQ48704473
Are the post-inspiratory neurons in the decerebrate rat cranial motoneurons or interneurons?Q48707346
Glycine receptor-mediated fast synaptic inhibition in the brainstem respiratory systemQ48718207
Endogenous activation of NMDA and non-NMDA glutamate receptors on respiratory neurones in cat medullaQ48737103
Enhanced in vivo release of substance P in the nucleus tractus solitarii during hypoxia in the rabbit: role of peripheral inputQ48738627
Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor.Q44349908
Opposite effects of the delta- and mu-opioid receptor agonists on ventilation in conscious adult dogsQ44351813
mu Receptors and opioid cardiovascular effects in the NTS of rat.Q44353348
Interaction of naloxone with mu- and delta-opioid agonists on the respiration of ratsQ44353382
Role of excitatory amino acids in the generation and transmission of respiratory drive in neonatal rat.Q44625720
Effects of ethanol on expiratory neuronal activities in decerebrated catsQ44910702
Respiratory depressant effects of GABA alpha- and beta-receptor agonists in the cat.Q44985693
Modulation of respiratory rhythm in vitro: role of Gi/o protein-mediated mechanismsQ44993227
Characteristics of inspiratory inhibition by phasic volume feedback in catsQ45180714
Evidence that glycine and GABA mediate postsynaptic inhibition of bulbar respiratory neurons in the catQ45237947
Response of the medullary respiratory network of the cat to hypoxiaQ45731083
High incidence of sudden infant death syndrome among northern Indians and Alaska natives compared with southwestern Indians: possible role of smoking.Q45967898
Excitatory amino acid-mediated transmission of inspiratory drive to phrenic motoneuronsQ46078603
Pentobarbital-induced apneusis in intact, vagotomized, and pneumotaxic-lesioned catsQ46123079
Excitatory effects of thyrotropin-releasing hormone on neurons within the nucleus ambiguus of adult guinea pigsQ46432556
Multiple actions of 1S,3R-ACPD in modulating endogenous synaptic transmission to spinal respiratory motoneurons.Q46531813
Blockade of NMDA receptor-channels by MK-801 alters breathing in adult ratsQ46573666
Effects of N-methyl-D-aspartate (NMDA) antagonist MK-801 on breathing pattern in ratsQ46717072
Involvement of NMDA receptors in the respiratory phase transition is different in the adult guinea pig in vivo and in the isolated brain stem preparationQ46977858
Increased density of somatostatin binding sites in respiratory nuclei of the brainstem in sudden infant death syndromeQ47734405
In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxiaQ48097265
Monosynaptic transmission of respiratory drive to phrenic motoneurons from brainstem bulbospinal neurons in ratsQ48102800
A cholinergic mechanism involved in the respiratory chemosensitivity of the medulla oblongata in the cat.Q48104060
The excitability and rhythm of medullary respiratory neurons in the cat are altered by the serotonin receptor agonist 5-methoxy-N,N, dimethyltryptamineQ48106001
Effects of morphine and physostigmine on the ventilatory response to carbon dioxideQ48113462
GABA(A) receptor-mediated inspiratory termination evoked by vagal stimulation in decerebrate catsQ48122428
Involvement of pontile NMDA receptors in inspiratory termination in rat.Q48135685
Neuronal pacemaker for breathing visualized in vitroQ48146711
Influence of dopamine and norepinephrine on the central ventilatory response to hypoxia in conscious catsQ48153596
Mechanisms of respiratory rhythm generation change profoundly during early life in mice and ratsQ48154420
Role of N-methyl-D-aspartate receptors in the pontine pneumotaxic mechanism in the cat.Q48168467
Nucleus tractus solitarius and excitatory amino acids in afferent-evoked inspiratory terminationQ48169533
Pontine respiratory neurons in anesthetized cats.Q48174818
Retrotrapezoid nucleus glutamate injections: long-term stimulation of phrenic activityQ48185916
The differential organization of medullary post-inspiratory activitiesQ48188212
Cholinergic effects on spike-density and burst-duration of medullary respiration-related neurones in the rabbit: an iontophoretic studyQ48188269
Differential effects of excitatory amino acid receptor antagonism in the ventral respiratory groupQ48197190
Somatostatin depresses excitability in neurons of the solitary tract complex through hyperpolarization and augmentation of IM, a non-inactivating voltage-dependent outward current blocked by muscarinic agonistsQ33551501
Roles of ion channels in carotid body chemotransmission of acute hypoxiaQ33755847
Ultrastructural evidence for serotonin-immunoreactive terminals contacting phrenic motoneurons in the cat.Q34078227
Carotid body chemoreceptors: from natural stimuli to sensory dischargesQ34324365
Neurotransmitters in the CNS control of breathingQ34375977
Neuroanatomical patterns of the mu, delta, and kappa opioid receptors of rat brain as determined by quantitative in vitro autoradiographyQ34633094
Effects of almitrine bismesylate on the ionic currents of chemoreceptor cells from the carotid bodyQ34745146
Alteration of medullary respiratory unit discharge by iontophoretic application of putative neurotransmittersQ35177834
Distribution of neuropeptide immunoreactive nerve terminals within the subnuclei of the nucleus of the tractus solitarius of the ratQ36592166
Differential roles of opioid receptors in respiration, respiratory disease, and opiate-induced respiratory depressionQ37895578
Synaptic connections between medullary respiratory neurons and considerations on the genesis of respiratory rhythmQ37901317
Modulation of respiration during brain hypoxiaQ37910005
Opioids and breathingQ39477167
Role of ventrolateral medulla in regulation of respiratory and cardiovascular systemsQ39749008
Central chemoreceptorsQ39761619
Effects of opiates and methionine-enkephalin on pontine and bulbar respiratory neurones of the catQ40170296
Studies on the synaptic interconnection between bulbar respiratory neurones of catsQ40255387
Neurogenesis of respiratory rhythm in the mammalQ40262623
Central chemosensitivity and the reaction theoryQ40267278
Central control of breathing in mammals: neuronal circuitry, membrane properties, and neurotransmittersQ40576721
Peripheral chemoreceptors and cardiovascular regulationQ40674706
Plasticity of tyrosine hydroxylase gene expression in the rat nucleus tractus solitarius after ventilatory acclimatization to hypoxiaQ40929046
Retrotrapezoid nucleus (RTN) metabotropic glutamate receptors and long-term stimulation of ventilatory output. RTN glutamate receptors and breathing.Q40985927
Phrenic motoneurons in the cat: subpopulations and nature of respiratory drive potentialsQ41025010
Catecholaminergic depressant effects on bulbar respiratory mechanismsQ41046824
Generation of respiratory rhythm and pattern in mammals: insights from developmental studies.Q41110943
Differing activities of medullary respiratory neurons in eupnea and gaspingQ41185121
Peripheral and central dopamine receptors in respiratory controlQ41316211
O2-sensing mechanisms in excitable cells: role of plasma membrane K+ channelsQ41387718
Dopamine blockade alters ventilatory acclimatization to hypoxia in goatsQ41461772
Involvement of amino acids in periodic inhibitions of bulbar respiratory neuronesQ41533082
Pentobarbitone effects on respiration related units; selective depression of bulbopontine reticular neuronesQ41589777
Pulmonary afferent and central influences on respiratory phase-switching in the catQ41640463
Effects of doxapram on ionic currents recorded in isolated type I cells of the neonatal rat carotid bodyQ41652354
Short-latency excitation of phrenic motor output mediated by non-NMDA receptorsQ41667668
Neuronal mechanisms of respiratory rhythm generation: an approach using in vitro preparationQ41721697
Pharmacological profile of PD 117302, a selective kappa-opioid agonistQ41813703
Localization of mu- and delta-opioid receptors in cat respiratory areas: an autoradiographic studyQ41869419
Pharmacological characterization of 5-hydroxytryptamine-induced excitation of afferent cervical vagus nerve in anaesthetized ratsQ42146255
The bulbar network of respiratory neurons during apneusis induced by a blockade of NMDA receptorsQ42150867
Pharmacological identification of δ and μ opiate receptors on bulbar respiratory neuronsQ42242229
Different effects of μ and δ opiate agonists on respirationQ42246903
Effects of TRH and TRH analogues on the central regulation of breathing in the rat.Q42248522
The role of vagal afferents and carbon dioxide in the respiratory response to thyrotropin-releasing hormoneQ42527851
Autoradiographic distribution of mu1 and mu2 opioid binding in the mouse central nervous systemQ43607320
Monoaminergic and GABAergic terminations in phrenic nucleus of rat identified by immunohistochemical labelingQ43809539
Are there serotonergic projections from raphe and retrotrapezoid nuclei to the ventral respiratory group in the rat?Q43930064
Excitability changes of the inspiratory "off-switch" mechanism tested by electrical stimulation in nucleus parabrachialis in the catQ44064701
An intracellular study of respiratory neurons in the rostral ventrolateral medulla of the rat and their relationship to catecholamine-containing neuronsQ44108607
Involvement of N-methyl-D-aspartate (NMDA) receptors in respiratory rhythmogenesisQ44237801
Selective cardiorespiratory effects mediated by mu opioid receptors in the nucleus ambiguusQ44330330
Control of breathing by endogenous opioid peptides: possible involvement in sudden infant death syndrome☆Q44330683
Opioid peptide gene expression in the nucleus tractus solitarius of rat brain and increases induced by unilateral cervical vagotomy: implications for role of opioid neurons in respiratory control mechanismsQ44336459
cAMP-dependent reversal of opioid- and prostaglandin-mediated depression of the isolated respiratory network in newborn ratsQ44347118
ATP-sensitive K+ channels are functional in expiratory neurones of normoxic catsQ48752257
cAMP-dependent protein kinase modulates expiratory neurons in vivoQ48786669
Cholinoceptive properties of respiratory neurones in the rat medullaQ48787088
Local application of somatostatin in the rat ventrolateral brain medulla induces apneaQ48854229
Hypoxia, sleep and respiration in relation to opioids in developing swineQ48871402
GABA-immunoreactive boutons make synapses with inspiratory neurons of the dorsal respiratory groupQ48880408
Evidence that glutamate is the transmitter mediating respiratory drive from medullary premotor neurons to phrenic motoneurons: a double labeling study in the rat.Q48931510
Distribution of cholecystokinin (CCK) in the rat lower brain stem nucleiQ48953973
Substance P in the ventrolateral medulla oblongata regulates ventilatory responsesQ48966246
Serotonin immunoreactive boutons form close appositions with respiratory neurons of the dorsal respiratory group in the cat.Q48971994
Effects of glycine and GABA on bulbar respiratory neurons of cat.Q48984079
Thyrotropin-releasing hormone immunoreactive boutons form close appositions with medullary expiratory neurons in the rat.Q49011597
Selective depression by ethanol of upper airway respiratory motor activity in catsQ49071375
Obstructive sleep apnea. A common disorder exacerbated by alcoholQ49071774
Discharge patterns of laryngeal motoneurones in the cat: an intracellular studyQ49101015
Inhibitions mediated by glycine and GABAA receptors shape the discharge pattern of bulbar respiratory neuronsQ49111435
Local effects of substance P on respiratory regulation in the rat medulla oblongataQ49127948
Effects on iontophoretically applied acetylcholine on membrane potential and synaptic activity of bulbar respiratory neurones in decerebrate catsQ49136713
Thyrotropin-releasing hormone (TRH) depolarizes a subset of inspiratory neurons in the newborn mouse brain stem in vitroQ49138927
Effects of acetylcholine on respiratory neurones in the nucleus ambiguus-retroambigualis complex of the cat.Q49161570
The effects of intravenous naltrindole and naltrindole 5'-isothiocyanate on sufentanil-induced respiratory depression and antinociception in rats.Q51458268
Inspiration-promoting vagal reflex under NMDA receptor blockade in anaesthetized rabbits.Q51469147
Effects of halothane on the phrenic nerve responses to carbon dioxide mediated by carotid body chemoreceptors in vagotomized dogs.Q51532445
The effect of halothane on phrenic and chemoreceptor responses to hypoxia in anesthetized kittens.Q51566390
The effects of ketamine on renal sympathetic nerve activity and phrenic nerve activity in rabbits (with vagotomy) with and without afferent inputs from peripheral receptors.Q51579837
Differences in midazolam-induced breathing patterns in healthy volunteers.Q51598741
Effects of sevoflurane on respiratory activities in the phrenic nerve of decerebrate cats.Q51598748
Rat retrotrapezoid nucleus iono- and metabotropic glutamate receptors and the control of breathing.Q51615866
Serotonin 1A-receptor activation suppresses respiratory apneusis in the cat.Q51633937
NMDA and non-NMDA receptors may play distinct roles in timing mechanisms and transmission in the feline respiratory network.Q51642314
Calcium currents and calcium-dependent potassium currents in mammalian medullary respiratory neurones.Q51653492
Microiontophoresis of baclofen on membrane potential and input resistance in bulbar respiratory neurons in the cat.Q51655510
Cellular effects of isoflurane on bulbar respiratory neurons in decerebrate cats.Q51666282
Mechanisms underlying post-inspiratory depolarization in post-inspiratory neurons of the cat.Q51671637
Effects of halothane on membrane potential and discharge activity in pairs of bulbar respiratory neurons of decerebrate cats.Q51682356
A beta-carboline derivative (ZK 93426) counteracts the cardiorespiratory depressant effects of intravenous midazolam.Q51699849
Evidence for an involvement of NMDA and non-NMDA receptors in synaptic excitation of phrenic motoneurons in the rabbitQ51706028
Selective actions of anesthetic agents on membrane potential trajectory in bulbar respiratory neurons of cats.Q51732521
The influence of halothane and thiopental on respiratory-related nerve activities in decerebrate cats.Q51747351
Diazepam potentiates postsynaptic inhibition in bulbar respiratory neurons of cats.Q51750429
Electrophysiological properties of respiratory laryngeal motoneurons and effects of thiopental.Q51763082
N-methyl-D-aspartate (NMDA) receptors control respiratory off-switch in cat.Q51772047
Central respiratory depression induced by acetylcholinesterase inhibition: involvement of anaesthesia.Q51782678
Differential effects of halothane anesthesia on the pattern of discharge of inspiratory and expiratory neurons in the region of the retrofacial nucleus.Q51794530
Effects of halothane on medullary inspiratory neurons of the cat.Q51794885
Comparison of respiratory-related trigeminal, hypoglossal and phrenic activities.Q51820849
The effects of acetylcholine on bulbar respiratory related neurones. Consequences of anaesthesia by pentobarbital.Q51847644
Respiratory-related hypoglossal nerve activity: influence of anesthetics.Q51851882
Effect of ketamine on control of breathing in cats.Q51852045
Acute "tolerance" to the central respiratory effects of midazolam in the dogQ51859723
Somatostatin in the control of respirationQ69932394
Adaptation to reflex effects of prolonged lung inflationQ69943018
Projections from the ventral respiratory group to phrenic and intercostal motoneurons in cat: an autoradiographic studyQ69955600
Respiratory effects of the N-methyl-D-aspartate (NMDA) antagonist, MK-801, in intact and vagotomized chronic catsQ70249495
Reversal of respiratory responses to dopamine after dopamine antagonistsQ70322146
Quantitation and characterization of thyrotropin-releasing hormone in vagal nuclei and other regions of the medulla oblongata of the ratQ70428649
Facilitation of inspiration by intracerebroventricular injection of thyrotropin-releasing hormone in rabbitsQ70481583
Cardiorespiratory effects produced by blockade of excitatory amino acid receptors in catsQ70493755
Effects of CO2 and bronchoconstriction on costal and crural diaphragm electromyogramsQ70513704
Respiratory depression produced by glycine injected into the cisterna magna of catsQ70612051
Evidence for a monosynaptic connection between slowly adapting pulmonary stretch receptor afferents and inspiratory beta neuronesQ70759409
NMDA receptor-mediated transmission of carotid body chemoreceptor input to expiratory bulbospinal neurones in dogsQ70845787
5-HT2 receptor-controlled modulation of medullary respiratory neurones in the catQ70845792
Respiratory effects produced by microinjection of L-glutamate and an uptake inhibitor of L-glutamate into the caudal subretrofacial area of the medullaQ70911272
Prolonged stimulation of respiration by brain stem metabotropic glutamate receptorsQ70984063
Centrally and peripherally administered 5-HTP have opposite effects on respirationQ70986411
Effect of catecholamine depletion on ventilatory control in unanesthetized normoxic and hypoxic ratsQ71041805
Long-lasting hyperventilation induced by almitrine: evidence for a specific effect on carotid and thoracic chemoreceptorsQ71132541
Respiratory effects of beta-endorphin, D-Ala2-met-enkephalinamide, and Met-enkephalin injected into the lateral ventricle and the pontomedullary subarachnoid spaceQ71291876
Different mechanisms are involved in the respiratory depression and analgesia induced by neurotensin in ratsQ71324330
Post-synaptic inhibition of bulbar inspiratory neurones in the catQ71329793
Interaction of dopamine and haloperidol with O2 and CO2 chemoreception in carotid bodyQ71512025
Substance P-induced respiratory excitation is blunted by delta-receptor specific opioids in the rat medulla oblongataQ71518671
Pharmacological properties of peripherally induced postsynaptic potentials in bulbar respiratory neurons of decerebrate catsQ71538976
Protein kinase C pathways modulate respiratory pattern generation in the catQ71549870
NMDA receptors are involved at the ventrolateral nucleus tractus solitarii for termination of inspirationQ71572748
Effect of almitrine on ventilation and on diaphragm and geniohyoid muscle activity in the ratQ71681957
Membrane potentials of respiratory neurones during dizocilpine-induced apneusis in adult catsQ71718817
Pre-Botzinger complex in the catQ71978612
Combined blockade of NMDA and non-NMDA receptors produces respiratory arrest in the adult catQ71995126
Effects of serotonin and substance P on bulbar respiratory neurons in vivoQ72106155
Calcium-dependent conductances control neurones involved in termination of inspiration in catsQ72174139
Endogenous benzodiazepine system and regulation of respiration in the catQ72201528
Adenosinergic modulation of respiratory neurones and hypoxic responses in the anaesthetized catQ72300635
Adrenergic cell group in rostral ventrolateral medulla of cat: its correlation with central chemoreceptorsQ72480369
Modulation of the respiratory responses to hypoxia and hypercapnia by synaptic input onto caudal hypothalamic neuronsQ72641533
Late expiratory inhibition of stage 2 expiratory neurons in the cat--a correlate of expiratory terminationQ72712414
Evidence that substance P is a neurotransmitter of baro- and chemoreceptor afferents in nucleus tractus solitariusQ72842287
Excitability of bulbar respiratory neurones: A study using microiontophoretic applications of depolarizing agentsQ72852462
The roles of K+ conductance in expiratory pattern generation in anaesthetized catsQ72880340
Respiratory depression produced by activation of GABA receptors in hindbrain of catQ72912208
The central respiratory effects of acetylcholine vary with CSF pHQ73042423
Nucleus raphe obscurus evokes 5-HT-1A receptor-mediated modulation of respiratory neuronsQ73093928
Synaptic interactions between respiratory neurons during inspiratory on-switching evoked by vagal stimulation in decerebrate catsQ73315537
Modulation of the synaptic drive to respiratory premotor and motor neuronsQ73961290
Synaptic potentials in respiratory neurones during evoked phase switching after NMDA receptor blockade in the catQ74331921
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectneuropharmacologyQ3026765
P304page(s)277-304
P577publication date2000-06-01
P1433published inPharmacology & TherapeuticsQ3378596
P1476titleNeuropharmacology of control of respiratory rhythm and pattern in mature mammals
P478volume86

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Q44112596Group I and II metabotropic glutamate receptors modulate respiratory activity in the lamprey
Q44200037Hypercapnic and hypoxic ventilatory responses in long-term streptozotocin-diabetic rats during conscious and pentobarbital-induced anesthetic states
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