Early life exposure to maternal insulin resistance has persistent effects on hepatic NAFLD in juvenile nonhuman primates

scientific article

Early life exposure to maternal insulin resistance has persistent effects on hepatic NAFLD in juvenile nonhuman primates is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2337/DB14-0276
P932PMC publication ID4113070
P698PubMed publication ID24705404
P5875ResearchGate publication ID261408515

P50authorGerald I. ShulmanQ52509909
P2093author name stringKarim C El Kasmi
Stephanie R Thorn
Kevin L Grove
Jacob E Friedman
Bryan C Bergman
Karalee C Baquero
Sean A Newsom
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Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in miceQ43088513
Kupffer cell activation is a causal factor for hepatic insulin resistanceQ43252189
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Nonalcoholic fatty liver disease/nonalcoholic steatohepatitis in obese adolescents: a looming marker of cardiac dysfunctionQ44741522
Liver transplantation for nonalcoholic steatohepatitis: the new epidemicQ44777597
Long-term maternal high-fat feeding from weaning through pregnancy and lactation predisposes offspring to hypertension, raised plasma lipids and fatty liver in mice.Q46128368
Maternal obesity at conception programs obesity in the offspring.Q50140946
Maternal obesity programs offspring nonalcoholic fatty liver disease by innate immune dysfunction in mice.Q51280945
Maternal high-fat feeding primes steatohepatitis in adult mice offspring, involving mitochondrial dysfunction and altered lipogenesis gene expression.Q51610482
Hepatocellular carcinomas in patients with metabolic syndrome often develop without significant liver fibrosis: a pathological analysis.Q51665999
Genes involved in fatty acid partitioning and binding, lipolysis, monocyte/macrophage recruitment, and inflammation are overexpressed in the human fatty liver of insulin-resistant subjects.Q53533679
The influence of maternal body mass index on infant adiposity and hepatic lipid contentQ84237518
Perinatal exposure to a high-fat diet is associated with reduced hepatic sympathetic innervation in one-year old male Japanese macaquesQ27312641
Macrophages, inflammation, and insulin resistanceQ29614351
Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaBQ29619314
Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver diseaseQ29619334
Mechanisms for insulin resistance: common threads and missing linksQ29620447
C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosisQ33750735
A maternal "junk food" diet in pregnancy and lactation promotes nonalcoholic Fatty liver disease in rat offspringQ33772350
Maternal high fat diet is associated with decreased plasma n-3 fatty acids and fetal hepatic apoptosis in nonhuman primatesQ33833752
Increased intramuscular lipid synthesis and low saturation relate to insulin sensitivity in endurance-trained athletesQ33841171
Enzymes of triacylglycerol synthesis and their regulationQ33974340
Accumulation of natural killer T cells in progressive nonalcoholic fatty liver disease.Q34060210
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From NAFLD to NASH to cirrhosis-new insights into disease mechanisms.Q34365079
Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasisQ34646876
Transgenic increase in N-3/n-6 Fatty Acid ratio reduces maternal obesity-associated inflammation and limits adverse developmental programming in miceQ34795140
Obesity in pregnancy stimulates macrophage accumulation and inflammation in the placentaQ34824188
Maternal high-fat diet disturbs uteroplacental hemodynamics and increases the frequency of stillbirth in a nonhuman primate model of excess nutritionQ35001389
Endothelial NO/cGMP/VASP signaling attenuates Kupffer cell activation and hepatic insulin resistance induced by high-fat feedingQ35405243
Human fatty liver disease: old questions and new insightsQ35588477
Current topic: comparative physiology of placental oxygen transportQ35691406
Increased hepatic glucose production in fetal sheep with intrauterine growth restriction is not suppressed by insulinQ36477267
Intrahepatic fat is increased in the neonatal offspring of obese women with gestational diabetesQ36724415
Increasing prevalence of nonalcoholic fatty liver disease among United States adolescents, 1988-1994 to 2007-2010.Q36831414
Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primatesQ37073698
High-fat diet consumption during pregnancy and the early post-natal period leads to decreased α cell plasticity in the nonhuman primateQ37133444
Kupffer cells in non-alcoholic fatty liver disease: the emerging view.Q37222183
Intramuscular lipid metabolism in the insulin resistance of smokingQ37360416
Developmental programming by maternal insulin resistance: hyperinsulinemia, glucose intolerance, and dysregulated lipid metabolism in male offspring of insulin-resistant mice.Q37510162
Alternative Macrophage Activation and MetabolismQ37804862
Inflammation and lipid signaling in the etiology of insulin resistanceQ38007632
Maternal adiposity--a determinant of perinatal and offspring outcomes?Q38046084
Dissociating fatty liver and diabetesQ38050214
CELL BIOLOGY SYMPOSIUM: Impacts of maternal obesity on placental and gut inflammation and healthQ38163518
Salmonella choleraesuis and Salmonella typhimurium associated with liver cells after intravenous inoculation of rats are localized mainly in Kupffer cells and multiply intracellularlyQ40147215
P433issue8
P407language of work or nameEnglishQ1860
P921main subjectinsulin resistanceQ1053470
preproinsulinQ7240673
P1104number of pages12
P304page(s)2702-2713
P577publication date2014-04-04
P1433published inDiabetesQ895262
P1476titleEarly life exposure to maternal insulin resistance has persistent effects on hepatic NAFLD in juvenile nonhuman primates
P478volume63

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