Epidemiology and pathogenesis of Neisseria meningitidis

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Epidemiology and pathogenesis of Neisseria meningitidis is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S1286-4579(00)00356-7
P698PubMed publication ID10884620

P50authorDavid S. StephensQ114922232
P2093author name stringY L Tzeng
P2860cites workMultilocus sequence typing: a portable approach to the identification of clones within populations of pathogenic microorganismsQ24685491
Crystallographic structure reveals phosphorylated pilin from Neisseria: phosphoserine sites modify type IV pilus surface chemistry and fibre morphologyQ27639839
Structure of the fibre-forming protein pilin at 2.6 A resolutionQ27729288
Killing of Neisseria meningitidis by human neutrophils: implications for normal and complement-deficient individualsQ28290497
Lipooligosaccharides (LOS) of Neisseria gonorrhoeae and Neisseria meningitidis have components that are immunochemically similar to precursors of human blood group antigens. Carbohydrate sequence specificity of the mouse monoclonal antibodies that rQ28339099
N-Propionylated group B meningococcal polysaccharide mimics a unique bactericidal capsular epitope in group B Neisseria meningitidisQ28378942
A single bifunctional enzyme, PilD, catalyzes cleavage and N-methylation of proteins belonging to the type IV pilin familyQ28492973
Structural characterization of the lipid A component of pathogenic Neisseria meningitidisQ31120578
Iron acquisition systems in the pathogenic NeisseriaQ33670869
Mechanisms of neisserial serum resistanceQ33670874
The (alpha2-->8)-linked polysialic acid capsule and lipooligosaccharide structure both contribute to the ability of serogroup B Neisseria meningitidis to resist the bactericidal activity of normal human serumQ33769638
Molecular characterization and expression in Escherichia coli of the gene complex encoding the polysaccharide capsule of Neisseria meningitidis group BQ33841587
Human opsonins induced during meningococcal disease recognize outer membrane proteins PorA and PorBQ33867635
The fate of circulating haemoglobinQ34064709
Lipooligosaccharides: the principal glycolipids of the neisserial outer membraneQ34409045
Evidence for a common molecular origin of the capsule gene loci in gram-negative bacteria expressing group II capsular polysaccharidesQ34510802
Fate of the major outer membrane protein P.IA in early and late events of gonococcal infection of epithelial cellsQ67712206
Blocking of bactericidal killing of Neisseria meningitidis by antibodies directed against class 4 outer membrane proteinQ67865762
Interaction of Neisseria meningitidis with human nasopharyngeal mucosa: attachment and entry into columnar epithelial cellsQ70448879
Meningococcal Carriage in a Population of "Normal" FamiliesQ70551269
Capsule phase variation in Neisseria meningitidis serogroup B by slipped-strand mispairing in the polysialyltransferase gene (siaD): correlation with bacterial invasion and the outbreak of meningococcal diseaseQ71538870
Distinct mechanisms of interactions of Opc-expressing meningococci at apical and basolateral surfaces of human endothelial cells; the role of integrins in apical interactionsQ71669928
Production, characterization and control of a Neisseria meningitidis hexavalent class 1 outer membrane protein containing vesicle vaccineQ71690934
Prevalence of congenital or acquired complement deficiency in patients with sporadic meningococcal diseaseQ71693315
Killing of meningococci by neutrophils: effect of vaccination on patients with complement deficiencyQ72069438
A trial of a group A plus group C meningococcal polysaccharide-protein conjugate vaccine in African infantsQ72592778
Demonstration of lipooligosaccharide immunotype and capsule as virulence factors for Neisseria meningitidis using an infant mouse intranasal infection modelQ72682674
Fc gamma receptor IIa (CD32) polymorphism in fulminant meningococcal septic shock in childrenQ72727754
Identification of two major families of transferrin receptors among Neisseria meningitidis strains based on antigenic and genomic featuresQ72802204
Distribution of a lipooligosaccharide-specific sialyltransferase in pathogenic and non-pathogenic NeisseriaQ72820303
Effect of the (alpha 2-->8)-linked polysialic acid capsule on adherence of Neisseria meningitidis to human mucosal cellsQ72940983
Outer membrane vesicle vaccines made from short-chain lipopolysaccharide mutants of serogroup B Neisseria meningitidis: effect of the carbohydrate chain length on the immune responseQ73671203
New Zealand epidemic of meningococcal disease identified by a strain with phenotype B:4:P1.4.Q74184869
The lipooligosaccharide (LOS) of Neisseria meningitidis serogroup B strain NMB contains L2, L3, and novel oligosaccharides, and lacks the lipid-A 4'-phosphate substituentQ74802090
Discrimination between apo and iron-loaded forms of transferrin by transferrin binding protein B and its N-terminal subfragmentQ77564335
Genetic basis for biosynthesis, structure, and function of meningococcal lipooligosaccharide (endotoxin)Q77790093
Variation in plasminogen-activator-inhibitor-1 gene and risk of meningococcal septic shockQ78201109
The N-domain of the human CD66a adhesion molecule is a target for Opa proteins of Neisseria meningitidis and Neisseria gonorrhoeaeQ41148166
Carriage of Neisseria meningitidis and Neisseria lactamica in Infants and ChildrenQ41367652
The opcA and (psi)opcB regions in Neisseria: genes, pseudogenes, deletions, insertion elements and DNA islandsQ41482254
Pilus-mediated adhesion of Neisseria meningitidis: the essential role of cell contact-dependent transcriptional upregulation of the PilC1 proteinQ42458745
Molecular characterization of LbpB, the second lactoferrin-binding protein of Neisseria meningitidis.Q42673499
Identification and characterization of pilG, a highly conserved pilus-assembly gene in pathogenic NeisseriaQ42676806
Sialic acids of both the capsule and the sialylated lipooligosaccharide of Neisseria meningitis serogroup B are prerequisites for virulence of meningococci in the infant rat.Q43641259
Intercontinental spread of an epidemic group A Neisseria meningitidis strainQ44510020
Molecular epidemiology of sporadic (endemic) serogroup C meningococcal diseaseQ44540899
Variation in the tumor necrosis factor-alpha gene promoter region may be associated with death from meningococcal diseaseQ44660229
Epidemic meningococcal disease in Nairobi, Kenya, 1989. The Kenya/Centers for Disease Control (CDC) Meningitis Study GroupQ44771375
The porA gene in serogroup A meningococci: evolutionary stability and mechanism of genetic variationQ44983292
Variable expression of the Opc outer membrane protein in Neisseria meningitidis is caused by size variation of a promoter containing poly-cytidineQ47372926
Cell signaling by the type IV pili of pathogenic Neisseria.Q47682136
Structure and function of repetitive sequence elements associated with a highly polymorphic domain of the Neisseria meningitidis PilQ proteinQ47694549
Dynamics of carriage of Neisseria meningitidis in a group of military recruits: subtype stability and specificity of the immune response following colonizationQ47713825
Phase variation of HpuAB and HmbR, two distinct haemoglobin receptors of Neisseria meningitidis DNM2.Q47957751
A gonococcal porA pseudogene: implications for understanding the evolution and pathogenicity of Neisseria gonorrhoeaeQ48007023
PilC of Neisseria meningitidis is involved in class II pilus formation and restores pilus assembly, natural transformation competence and adherence to epithelial cells in PilC-deficient gonococci.Q48053210
Cloning of the lipooligosaccharide alpha-2,3-sialyltransferase from the bacterial pathogens Neisseria meningitidis and Neisseria gonorrhoeae.Q48057985
Modulation of Neisseria porin (PorB) by cytosolic ATP/GTP of target cells: parallels between pathogen accommodation and mitochondrial endosymbiosisQ48064228
Meningococcal pilin: a glycoprotein substituted with digalactosyl 2,4-diacetamido-2,4,6-trideoxyhexoseQ48070795
Functional implications of the expression of PilC proteins in meningococci.Q51039916
Variation in class 5 protein expression by serogroup A meningococci during a meningitis epidemic.Q53029070
Antibacterial and anti-inflammatory agents that target endotoxin.Q54138508
Promoter strength influences phase variation of neisserial opa genes.Q54449026
Immunologic response of man to group B meningococcal polysaccharide vaccines.Q54484873
Membrane cofactor protein (MCP or CD46) is a cellular pilus receptor for pathogenic Neisseria.Q54560552
Meningococcal Opa and Opc proteins: their role in colonization and invasion of human epithelial and endothelial cells.Q55065744
Maternal cigarette smoking and invasive meningococcal disease: a cohort study among young children in metropolitan Atlanta, 1989-1996Q56895103
Reassortment of pilin genes in Neisseria gonorrhoeae occurs by two distinct mechanismsQ56984407
Respiratory viruses and mycoplasma as cofactors for epidemic group A meningococcal meningitisQ58481192
Neisseria PilC protein identified as type-4 pilus tip-located adhesinQ59097833
Antigenic variation of pilin regulates adhesion of Neisseria meningitidis to human epithelial cellsQ59632147
Naturally occurring insertional inactivation of theporAgene ofNeisseria meningitidisby integration of IS1301Q63371254
Tobacco smoke as a risk factor for meningococcal diseaseQ64133556
Consequences of the loss of O-linked glycosylation of meningococcal type IV pilin on piliation and pilus-mediated adhesionQ64449937
Experimental human gonococcal urethritis: 250 Neisseria gonorrhoeae MS11mkC are infectiveQ64450131
Analysis in Neisseria meningitidis and other Neisseria species of genes homologous to the FKBP immunophilin familyQ64450326
The lipooligosaccharide immunotype as a virulence determinant in Neisseria meningitidisQ67468255
Structural determination of the polysaccharide antigens of Neisseria meningitidis serogroups Y, W-135, and BO1Q67517989
Safety and immunogenicity of meningococcal A and C polysaccharide conjugate vaccine in adults.Q34533811
Roles of pilin and PilC in adhesion of Neisseria meningitidis to human epithelial and endothelial cellsQ35196315
Molecular mechanisms in the compartmentalized inflammatory response presenting as meningococcal meningitis or septic shockQ35221980
Invasion of primary nasopharyngeal epithelial cells by Neisseria meningitidis is controlled by phase variation of multiple surface antigens.Q35509909
Evaluation of recombinant transferrin-binding protein B variants from Neisseria meningitidis for their ability to induce cross-reactive and bactericidal antibodies against a genetically diverse collection of serogroup B strainsQ35533300
Intercontinental spread of a genetically distinctive complex of clones of Neisseria meningitidis causing epidemic diseaseQ35615516
Capsule switching of Neisseria meningitidisQ35910306
Shuttle mutagenesis of Neisseria gonorrhoeae: pilin null mutations lower DNA transformation competenceQ36155856
Human immunity to the meningococcus. 3. Preparation and immunochemical properties of the group A, group B, and group C meningococcal polysaccharidesQ36269711
Release of endotoxin in the form of cell wall blebs during in vitro growth of Neisseria meningitidisQ36272616
Pili of Neisseria meningitidis. Analysis of structure and investigation of structural and antigenic relationships to gonococcal piliQ36350140
Local production of tumor necrosis factor alpha, interleukin 1, and interleukin 6 in meningococcal meningitis. Relation to the inflammatory responseQ36357094
The meningococcal PilT protein is required for induction of intimate attachment to epithelial cells following pilus-mediated adhesion.Q36456158
The Stonehouse survey: nasopharyngeal carriage of meningococci and Neisseria lactamicaQ36472571
Secretor status, smoking and carriage of Neisseria meningitidisQ36504864
Neisseria meningitidis with decreased susceptibility to penicillin in Saskatchewan, CanadaQ36523218
Natural genetic exchange between Haemophilus and Neisseria: intergeneric transfer of chromosomal genes between major human pathogensQ36524212
Gonococcal and meningococcal pathogenesis as defined by human cell, cell culture, and organ culture assaysQ36634342
Tn916-generated, lipooligosaccharide mutants of Neisseria meningitidis and Neisseria gonorrhoeaeQ36675071
Suppression of an absolute defect in type IV pilus biogenesis by loss-of-function mutations in pilT, a twitching motility gene in Neisseria gonorrhoeaeQ36758783
Analysis of the genetic differences between Neisseria meningitidis and Neisseria gonorrhoeae: two closely related bacteria expressing two different pathogenicitiesQ36825332
Eight lipooligosaccharides of Neisseria meningitidis react with a monoclonal antibody which binds lacto-N-neotetraose (Gal beta 1-4GlcNAc beta 1-3Gal beta 1-4Glc).Q36988022
Clonal diversity of Neisseria meningitidis from a population of asymptomatic carriersQ36998242
Molecular characterization of hpuAB, the haemoglobin-haptoglobin-utilization operon of Neisseria meningitidisQ38348677
HmbR outer membrane receptors of pathogenic Neisseria spp.: iron-regulated, hemoglobin-binding proteins with a high level of primary structure conservationQ38354804
"Love's labours lost": failure to implement mass vaccination against group A meningococcal meningitis in sub-Saharan AfricaQ38556070
Meningococcal disease and season in sub-Saharan AfricaQ39032797
Deletion of porA by recombination between clusters of repetitive extragenic palindromic sequences in Neisseria meningitidisQ39510841
Expression of sialic acid and polysialic acid in serogroup B Neisseria meningitidis: divergent transcription of biosynthesis and transport operons through a common promoter region.Q39841939
Meningococcal Disease: Still with UsQ40145726
Sporadic meningococcal disease in adults: results of a 5-year population-based studyQ40374333
Clonal spread of serogroup A meningococci: a paradigm for the analysis of microevolution in bacteriaQ40734532
Complement deficiency states and meningococcal diseaseQ40804745
Neisserial porin (PorB) causes rapid calcium influx in target cells and induces apoptosis by the activation of cysteine proteasesQ40980664
Neisseria meningitidis producing the Opc adhesin binds epithelial cell proteoglycan receptorsQ41046627
Bacterial transferrin and lactoferrin receptorsQ41051437
Modulation of cell surface sialic acid expression in Neisseria meningitidis via a transposable genetic element.Q41063588
Phase variation of gonococcal pili by frameshift mutation in pilC, a novel gene for pilus assemblyQ41079923
P433issue6
P921main subjectNeisseria meningitidisQ154625
pathogenesisQ372016
P304page(s)687-700
P577publication date2000-05-01
P1433published inMicrobes and InfectionQ15760242
P1476titleEpidemiology and pathogenesis of Neisseria meningitidis
P478volume2

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cites work (P2860)
Q44655589A Neisserial autotransporter NalP modulating the processing of other autotransporters
Q30543327A network of enzymes involved in repair of oxidative DNA damage in Neisseria meningitidis
Q44814588A novel "clip-and-link" activity of repeat in toxin (RTX) proteins from gram-negative pathogens. Covalent protein cross-linking by an Asp-Lys isopeptide bond upon calcium-dependent processing at an Asp-Pro bond
Q36202090Acute meningoencephalitis in hospitalised children in southern Bangladesh
Q33555516Alternative substrates selective for S-adenosylmethionine synthetases from pathogenic bacteria
Q40094213An epitope-imprinted piezoelectric diagnostic tool for Neisseria meningitidis detection
Q33399118Application of atmospheric pressure matrix-assisted laser desorption/ionization mass spectrometry for rapid identification of Neisseria species
Q37590858Association between population prevalence of smoking and incidence of meningococcal disease in Norway, Sweden, Denmark and the Netherlands between 1975 and 2009: a population-based time series analysis
Q96231550Asymptomatic carriers of Neisseria meningitidis and Moraxella catarrhalis in healthy children
Q34976489Autoregulation of the MisR/MisS two-component signal transduction system in Neisseria meningitidis
Q40131360Biochemical and biophysical characterization of the sialyl-/hexosyltransferase synthesizing the meningococcal serogroup W135 heteropolysaccharide capsule
Q34939544Characterization of DsbD in Neisseria meningitidis.
Q50857953Characterization of ST-4821 complex, a unique Neisseria meningitidis clone.
Q33685515Clinical and laboratory evidence for Neisseria meningitidis biofilms
Q35784362Clonal distribution of invasive Neisseria meningitidis serogroup C strains circulating from 1976 to 2005 in greater Sao Paulo, Brazil
Q36434366Comparison of Phenotypic and Genotypic Approaches to Capsule Typing of Neisseria meningitidis by Use of Invasive and Carriage Isolate Collections
Q97644970Construction and assessment of the immunogenicity and bactericidal activity of fusion protein porin A from Neisseria meningitidis serogroups A and B admixed with OMV adjuvant as a novel vaccine candidate
Q42124015Crystallization and preliminary crystallographic characterization of the iron-regulated outer membrane lipoprotein FrpD from Neisseria meningitidis
Q58554891Development and Assessment of a Diagnostic DNA Oligonucleotide Microarray for Detection and Typing of Meningitis-Associated Bacterial Species
Q37597599Distribution of serogroups and genotypes among disease-associated and carried isolates of Neisseria meningitidis from the Czech Republic, Greece, and Norway
Q35972042Diversity in pathogenicity can cause outbreaks of meningococcal disease
Q35390370Effectiveness of meningococcal C conjugate vaccine in Salvador, Brazil: a case-control study
Q34644525Epidemic meningitis, meningococcaemia, and Neisseria meningitidis
Q90494296Evaluation of Neisseria meningitidis Carriage with the Analysis of Serogroups, Genogroups and Clonal Complexes among Polish Soldiers
Q43801521Evaluation of serogroup C and ACWY meningococcal vaccine programs: projected impact on disease burden according to a stochastic two-strain dynamic model
Q37862579Genetic variation of innate immune response genes in invasive pneumococcal and meningococcal disease applied to the pathogenesis of meningitis
Q35757635Genome-Based Characterization of Emergent Invasive Neisseria meningitidis Serogroup Y Isolates in Sweden from 1995 to 2012.
Q24796555Geographic correlation between deprivation and risk of meningococcal disease: an ecological study
Q35737256Hyperinvasive Meningococci Induce Intra-nuclear Cleavage of the NF-κB Protein p65/RelA by Meningococcal IgA Protease
Q64072199Immunogenicity profiling of protein antigens from capsular group B Neisseria meningitidis
Q28972389Infections of People with Complement Deficiencies and Patients Who Have Undergone Splenectomy
Q91738418Insights on Population Structure and Within-Host Genetic Changes among Meningococcal Carriage Isolates from U.S. Universities
Q39655777Interaction of Neisseria meningitidis with human meningeal cells induces the secretion of a distinct group of chemotactic, proinflammatory, and growth-factor cytokines.
Q38921081Interactions of meningococcal virulence factors with endothelial cells at the human blood-cerebrospinal fluid barrier and their role in pathogenicity
Q55246888Interplay Between Virulence and Variability Factors as a Potential Driver of Invasive Meningococcal Disease.
Q24600500Mapping of theNeisseria meningitidisNadA Cell-Binding Site: Relevance of Predicted α-Helices in the NH2-Terminal and Dimeric Coiled-Coil Regions
Q37784891Meningitis in Neonates: Bench to Bedside
Q40602522Meningococcal carriage among local inhabitants during the pilgrimage 2000-2001.
Q33274203Meningococcal genetic variation mechanisms viewed through comparative analysis of serogroup C strain FAM18.
Q36949981Meningococcal outer membrane protein NhhA is essential for colonization and disease by preventing phagocytosis and complement attack
Q27028161Meningococcal serogroups A, C, W-135, and Y tetanus toxoid conjugate vaccine: a new conjugate vaccine against invasive meningococcal disease
Q36421536MisR/MisS two-component regulon in Neisseria meningitidis.
Q33372688Modification of lipooligosaccharide with phosphoethanolamine by LptA in Neisseria meningitidis enhances meningococcal adhesion to human endothelial and epithelial cells
Q42088370Molecular characterization of Neisseria meningitidis isolates recovered from 11-19-year-old meningococcal carriers in Salvador, Brazil.
Q35947434Multiple Functions of Glutamate Uptake via Meningococcal GltT-GltM L-Glutamate ABC Transporter in Neisseria meningitidis Internalization into Human Brain Microvascular Endothelial Cells
Q34008919Neisseria meningitidis RTX protein FrpC induces high levels of serum antibodies during invasive disease: polymorphism of frpC alleles and purification of recombinant FrpC.
Q34856191Neisseria meningitidis RTX proteins are not required for virulence in infant rats
Q34632986Neisseria meningitidis: biology, microbiology, and epidemiology.
Q91199458Neisseria meningitidis: using genomics to understand diversity, evolution and pathogenesis
Q37683101Pathogenesis and pathophysiology of bacterial CNS infections
Q35017740Pathogenesis and pathophysiology of pneumococcal meningitis
Q34428829Persistence of hyperinvasive meningococcal strain types during global spread as recorded in the PubMLST database
Q36728528Phenotypic and molecular characterization of serogroup C Neisseria meningitidis associated with an outbreak in Bahia, Brazil
Q37455163Postgenomics of Neisseria meningitidis: an update.
Q41816416Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulence
Q51853249Rapid identification of herd effects with the introduction of serogroup C meningococcal conjugate vaccine in Ontario, Canada, 2000-2006.
Q35191828Recognition of Neisseria meningitidis by the long pentraxin PTX3 and its role as an endogenous adjuvant
Q33928835Regulation of the type I protein secretion system by the MisR/MisS two-component system in Neisseria meningitidis
Q33355824Reverse transcriptase-PCR differential display analysis of meningococcal transcripts during infection of human cells: up-regulation of priA and its role in intracellular replication
Q28828692Review of meningococcal vaccines with updates on immunization in adults
Q48004357Role of lipopolysaccharide in the induction of type I interferon-dependent cross-priming and IL-10 production in mice by meningococcal outer membrane vesicles
Q33650066Spatio-temporal factors associated with meningococcal meningitis annual incidence at the health centre level in Niger, 2004-2010.
Q34075291Structural alterations in a component of cytochrome c oxidase and molecular evolution of pathogenic Neisseria in humans
Q48030042Synthesis of Neisseria meningitidis serogroup W135 capsular oligosaccharides for immunogenicity comparison and vaccine development
Q43126225System specificity of the TpsB transporters of coexpressed two-partner secretion systems of Neisseria meningitidis
Q33592154Temporal analysis of the incidence of meningitis in the Tehran metropolitan area, 1999-2005.
Q45138614The Neisseria meningitidis outer membrane lipoprotein FrpD binds the RTX protein FrpC.
Q40025165The acute-phase reactant C-reactive protein binds to phosphorylcholine-expressing Neisseria meningitidis and increases uptake by human phagocytes
Q35724206The impact of aggregating serogroups in dynamic models of Neisseria meningitidis transmission.
Q45572517The pathogenesis of infection and immune response
Q40580834The use of dexamethasone in bacterial meningitis in children and adults: a retrospective analysis
Q34042132Variable-number tandem repeat analysis of meningococcal isolates belonging to the sequence type 162 complex
Q34746786Variation and molecular evolution of HmbR, the Neisseria meningitidis haemoglobin receptor
Q33348906Virulence determinants involved in differential host niche adaptation of Neisseria meningitidis and Neisseria gonorrhoeae
Q33730806Whole genome sequencing reveals within-host genetic changes in paired meningococcal carriage isolates from Ethiopia

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